𝕏

Task 56004654

Name HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1
Workunit 26596812
Created 3 Jul 2024, 23:45:58 UTC
Sent 4 Jul 2024, 1:01:06 UTC
Report deadline 7 Jul 2024, 10:37:06 UTC
Received 8 Jul 2024, 1:55:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217799
Run time 1 hours 39 min 26 sec
CPU time 56 min 43 sec
Validate state Valid
Credit 72.26
Device peak FLOPS 5.48 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.50 MB
Peak swap size 391.83 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 60599483, states[0] = -18.907890, states[40]= 0.001060
Saving checkpoint... 
Iteration: 120336265, states[0] = -94.970164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181951499, states[0] = -95.006283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235778493, states[0] = -94.924901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293194891, states[0] = -94.798814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347265752, states[0] = -94.911504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409426429, states[0] = -95.000481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455238995, states[0] = -94.877344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479432670, states[0] = -95.001852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531035360, states[0] = 17.278912, states[40]= 0.005547
Saving checkpoint... 
Iteration: 559587925, states[0] = -7.766394, states[40]= 0.002815


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 559587925
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -7.766394 (After loading)
 - states[40]: 0.002815 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 614101846, states[0] = -20.244019, states[40]= 0.000964
Saving checkpoint... 
Iteration: 662225615, states[0] = -94.856433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713963877, states[0] = -95.007672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755779032, states[0] = -94.924996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757244579, states[0] = -94.885042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761894619, states[0] = -94.991599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783163185, states[0] = -91.235207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802684635, states[0] = -94.772523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820781991, states[0] = -94.927774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831697311, states[0] = -94.803517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849270573, states[0] = -94.916386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865142234, states[0] = -60.953020, states[40]= 0.000005
Saving checkpoint... 
Iteration: 882159980, states[0] = -87.316213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933352420, states[0] = -94.975197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958168890, states[0] = -94.076649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959243952, states[0] = -94.884045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960539345, states[0] = 15.905588, states[40]= 0.005305
Saving checkpoint... 
Iteration: 961836399, states[0] = -94.967063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973770918, states[0] = -94.916668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990287509, states[0] = -94.932703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002564904, states[0] = 5.782788, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1013726858, states[0] = -94.858248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025532418, states[0] = 18.236828, states[40]= 0.005807
Saving checkpoint... 
Iteration: 1040655700, states[0] = -80.084656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050600947, states[0] = -19.404829, states[40]= 0.001020
Saving checkpoint... 
Iteration: 1060213298, states[0] = -94.834638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069891785, states[0] = -94.990497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076559167, states[0] = 8.268794, states[40]= 0.004891
Saving checkpoint... 
Iteration: 1084815616, states[0] = -94.954383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097519524, states[0] = 21.600286, states[40]= 0.010143
Saving checkpoint... 
Iteration: 1110251336, states[0] = -94.893791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117271696, states[0] = -94.917390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127823807, states[0] = -94.959629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137305877, states[0] = -94.947496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144451168, states[0] = -95.005168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153997992, states[0] = -95.012193, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1153997992
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.012193 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1207674063, states[0] = -94.622400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257076603, states[0] = -0.086743, states[40]= 0.004256


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1257076603
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -0.086743 (After loading)
 - states[40]: 0.004256 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1319477034, states[0] = -95.009319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368218038, states[0] = -94.842999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428809523, states[0] = -94.949950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493635255, states[0] = -53.082307, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1561456540, states[0] = -95.243152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564294158, states[0] = -30.023044, states[40]= 0.000469
Saving checkpoint... 
Iteration: 1565232205, states[0] = -78.494685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566309416, states[0] = 24.543183, states[40]= 0.060225
Saving checkpoint... 
Iteration: 1580783102, states[0] = -18.335197, states[40]= 0.001216
Saving checkpoint... 
Iteration: 1597030186, states[0] = -75.524377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625127145, states[0] = 18.558974, states[40]= 0.007667
Saving checkpoint... 
Iteration: 1632857391, states[0] = -95.253314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636093956, states[0] = -95.161085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650902184, states[0] = 44.171102, states[40]= 0.081401
Saving checkpoint... 
Iteration: 1663841038, states[0] = 12.371004, states[40]= 0.006051
Saving checkpoint... 
Iteration: 1674132482, states[0] = -80.007377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686923784, states[0] = 19.803810, states[40]= 0.008711
Saving checkpoint... 
Iteration: 1698596740, states[0] = -95.286366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711395218, states[0] = -95.164407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757346575, states[0] = -95.242682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789190324, states[0] = -95.282029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790356751, states[0] = -95.253554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791431400, states[0] = -78.040398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792505444, states[0] = 28.943312, states[40]= 0.125532
Saving checkpoint... 
Iteration: 1795750104, states[0] = -95.246578, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_781_1_r333802083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1795750104
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.246578 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1851837915, states[0] = -94.982283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914515345, states[0] = 22.328299, states[40]= 0.017453
Saving checkpoint... 
Iteration: 1972560748, states[0] = 7.592553, states[40]= 0.004867
Saving checkpoint... 
Iteration: 2028157949, states[0] = -84.020122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080185254, states[0] = -94.773777, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.887646
 - CaMKt in component CaMK (millimolar): 0.007069
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.621566
 - nass in component intracellular_ions (millimolar): 6.621626
 - ki in component intracellular_ions (millimolar): 145.354467
 - kss in component intracellular_ions (millimolar): 145.354448
 - cansr in component intracellular_ions (millimolar): 1.318735
 - cajsr in component intracellular_ions (millimolar): 1.280585
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003624
 - hf in component INa (dimensionless): 0.879754
 - hs in component INa (dimensionless): 0.879749
 - j in component INa (dimensionless): 0.879720
 - hsp in component INa (dimensionless): 0.725365
 - jp in component INa (dimensionless): 0.879701
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709260
 - hLp in component INaL (dimensionless): 0.450747
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619805
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694320
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933977
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334805
 - xs1 in component IKs (dimensionless): 0.243846
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:55:27 (74832): called boinc_finish(0)

</stderr_txt>
]]>


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