𝕏

Task 56004582

Name HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_377_1
Workunit 26596776
Created 3 Jul 2024, 23:45:53 UTC
Sent 4 Jul 2024, 1:04:41 UTC
Report deadline 7 Jul 2024, 10:40:41 UTC
Received 4 Jul 2024, 12:08:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241135
Run time 1 hours 39 min 42 sec
CPU time 1 hours 36 min 24 sec
Validate state Valid
Credit 62.71
Device peak FLOPS 6.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.22 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_377_1_r1853534192_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_377_1_r1853534192_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4810550, states[0] = -95.076282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16934209, states[0] = -95.076974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30109448, states[0] = -31.719095, states[40]= 0.000381
Saving checkpoint... 
Iteration: 43037557, states[0] = 15.663751, states[40]= 0.005406
Saving checkpoint... 
Iteration: 56159883, states[0] = -91.231349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65379623, states[0] = -95.006280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78075985, states[0] = -0.940667, states[40]= 0.004142
Saving checkpoint... 
Iteration: 91082300, states[0] = -4.990396, states[40]= 0.003413
Saving checkpoint... 
Iteration: 103791240, states[0] = -94.946031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116962424, states[0] = -95.015455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130132111, states[0] = -52.139197, states[40]= 0.000019
Saving checkpoint... 
Iteration: 142691399, states[0] = -94.797859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155456101, states[0] = -95.012170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168317690, states[0] = -94.961691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181597022, states[0] = -17.438043, states[40]= 0.001182
Saving checkpoint... 
Iteration: 194870747, states[0] = -94.988386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208316384, states[0] = -94.960310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221020651, states[0] = 21.040077, states[40]= 0.009219
Saving checkpoint... 
Iteration: 233165382, states[0] = -93.613492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245804971, states[0] = -94.952137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259007364, states[0] = 24.729805, states[40]= 0.096865
Saving checkpoint... 
Iteration: 272404851, states[0] = -94.999478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285297844, states[0] = -94.946584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298524595, states[0] = 20.102555, states[40]= 0.007271
Saving checkpoint... 
Iteration: 311720390, states[0] = -94.852886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324026752, states[0] = 19.522888, states[40]= 0.006693
Saving checkpoint... 
Iteration: 337459339, states[0] = -95.011580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349089503, states[0] = -10.481072, states[40]= 0.002245
Saving checkpoint... 
Iteration: 361815771, states[0] = -94.959584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374698718, states[0] = -94.811714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382967694, states[0] = -95.012926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395927487, states[0] = -95.005178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404934323, states[0] = -95.006700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416902618, states[0] = -94.998710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430063614, states[0] = 5.679974, states[40]= 0.004775
Saving checkpoint... 
Iteration: 443513278, states[0] = 22.431558, states[40]= 0.025579
Saving checkpoint... 
Iteration: 453695255, states[0] = -94.804445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467156173, states[0] = -84.194875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480402501, states[0] = -94.998635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493178481, states[0] = -94.749280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505556665, states[0] = 8.689283, states[40]= 0.004904
Saving checkpoint... 
Iteration: 518334677, states[0] = -94.970975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531537237, states[0] = 16.173913, states[40]= 0.005429
Saving checkpoint... 
Iteration: 540165720, states[0] = -93.719240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553498591, states[0] = -95.017066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566854663, states[0] = -94.981007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579811326, states[0] = -94.956415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592628753, states[0] = -48.378017, states[40]= 0.000036
Saving checkpoint... 
Iteration: 606169194, states[0] = -94.394188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619111068, states[0] = -30.744743, states[40]= 0.000431
Saving checkpoint... 
Iteration: 632324071, states[0] = -94.964717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644751937, states[0] = -94.899776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657321618, states[0] = -94.963177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670680654, states[0] = -94.763464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683512491, states[0] = 22.583440, states[40]= 0.030091
Saving checkpoint... 
Iteration: 696645501, states[0] = -67.489887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709842311, states[0] = -94.974927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722888477, states[0] = -94.994119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736285301, states[0] = -94.935627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749260663, states[0] = -94.910314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762423416, states[0] = -95.003986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775688702, states[0] = -94.789725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789014961, states[0] = 22.131382, states[40]= 0.018663
Saving checkpoint... 
Iteration: 802653731, states[0] = -79.983457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814992704, states[0] = -95.016183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827921173, states[0] = -95.003402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840559039, states[0] = 7.689092, states[40]= 0.004867
Saving checkpoint... 
Iteration: 854019382, states[0] = 21.309124, states[40]= 0.010316
Saving checkpoint... 
Iteration: 866776860, states[0] = -94.927580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879274666, states[0] = -94.925388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892373688, states[0] = -94.988747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905358811, states[0] = -94.982648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918239099, states[0] = -94.882182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929855571, states[0] = -94.981188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943041269, states[0] = 14.717553, states[40]= 0.005225
Saving checkpoint... 
Iteration: 955864801, states[0] = -94.985172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969195193, states[0] = -94.803982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981986847, states[0] = -95.015323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995480103, states[0] = -95.014392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008731592, states[0] = -94.870849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022090587, states[0] = -11.440495, states[40]= 0.002058
Saving checkpoint... 
Iteration: 1034186159, states[0] = -94.783159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047427246, states[0] = -95.004706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060168130, states[0] = -94.253971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073217483, states[0] = -94.847284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086169214, states[0] = -94.396025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099739927, states[0] = -94.883258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111448523, states[0] = -95.009130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123299496, states[0] = -94.947329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132197539, states[0] = -94.808790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144537838, states[0] = 15.961471, states[40]= 0.005393
Saving checkpoint... 
Iteration: 1157621014, states[0] = -40.402376, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1170588530, states[0] = -9.636326, states[40]= 0.002418
Saving checkpoint... 
Iteration: 1183343940, states[0] = -94.975455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196441763, states[0] = -95.007751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208395255, states[0] = -94.995988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221762171, states[0] = -94.911750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234025914, states[0] = 19.753666, states[40]= 0.006893
Saving checkpoint... 
Iteration: 1247471476, states[0] = -95.012963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259966104, states[0] = -95.012112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273339022, states[0] = -94.972848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285831199, states[0] = -94.968526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299068562, states[0] = 3.347678, states[40]= 0.004619
Saving checkpoint... 
Iteration: 1311947689, states[0] = -95.008843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325152721, states[0] = -78.259150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338513189, states[0] = 22.448312, states[40]= 0.026042
Saving checkpoint... 
Iteration: 1351839862, states[0] = -94.973242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364497375, states[0] = -95.016405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375498618, states[0] = -95.016545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383945082, states[0] = -95.008292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396299654, states[0] = -94.947278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409375196, states[0] = -94.988988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417669869, states[0] = -94.461862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430980128, states[0] = -95.014118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443591949, states[0] = -12.671412, states[40]= 0.001834
Saving checkpoint... 
Iteration: 1456227483, states[0] = -94.864030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469248846, states[0] = -94.895258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482770875, states[0] = -94.921110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495192250, states[0] = -94.797318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508045730, states[0] = -95.199652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520767812, states[0] = -3.255255, states[40]= 0.004181
Saving checkpoint... 
Iteration: 1533917759, states[0] = 21.702306, states[40]= 0.013959
Saving checkpoint... 
Iteration: 1546615322, states[0] = -55.761742, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1556671642, states[0] = -95.263615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569430892, states[0] = -79.127192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581263282, states[0] = -95.262824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593398418, states[0] = -36.767907, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1601668338, states[0] = -95.270135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610334190, states[0] = -95.234042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622788269, states[0] = -25.757069, states[40]= 0.000668
Saving checkpoint... 
Iteration: 1636171755, states[0] = -95.275034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649235440, states[0] = -87.977461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661986144, states[0] = -95.286974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675047306, states[0] = -94.833675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687978645, states[0] = -95.137020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699695775, states[0] = -95.174125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712606542, states[0] = -95.194234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725699535, states[0] = -38.218930, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1739088265, states[0] = -95.288824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747492112, states[0] = -95.291534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760548410, states[0] = -94.903565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773219864, states[0] = -95.216018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786091377, states[0] = -95.165272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799371315, states[0] = -95.275457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811741108, states[0] = -94.929911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825107040, states[0] = -28.917017, states[40]= 0.000517
Saving checkpoint... 
Iteration: 1837988334, states[0] = -95.037915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850599919, states[0] = -21.063233, states[40]= 0.000902
Saving checkpoint... 
Iteration: 1863799664, states[0] = -94.957772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877330956, states[0] = -94.975199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890422824, states[0] = -95.007974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899878064, states[0] = -94.993404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912355869, states[0] = -94.983223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925167611, states[0] = -94.192336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937687603, states[0] = -94.787518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950717043, states[0] = -94.846741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963164737, states[0] = -93.388423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972531695, states[0] = 18.035096, states[40]= 0.005902
Saving checkpoint... 
Iteration: 1985674857, states[0] = -94.699981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998709666, states[0] = -94.832474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012065838, states[0] = 4.652738, states[40]= 0.004714
Saving checkpoint... 
Iteration: 2024938364, states[0] = -95.006565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033557047, states[0] = 8.528931, states[40]= 0.004898
Saving checkpoint... 
Iteration: 2047013366, states[0] = 22.415178, states[40]= 0.025133
Saving checkpoint... 
Iteration: 2060182874, states[0] = -94.772264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073404698, states[0] = -94.998219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086780193, states[0] = -94.929986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098848441, states[0] = -94.977056, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892077
 - CaMKt in component CaMK (millimolar): 0.006963
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.592156
 - nass in component intracellular_ions (millimolar): 6.592216
 - ki in component intracellular_ions (millimolar): 145.385265
 - kss in component intracellular_ions (millimolar): 145.385246
 - cansr in component intracellular_ions (millimolar): 1.312657
 - cajsr in component intracellular_ions (millimolar): 1.274801
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879831
 - hs in component INa (dimensionless): 0.879826
 - j in component INa (dimensionless): 0.879797
 - hsp in component INa (dimensionless): 0.725510
 - jp in component INa (dimensionless): 0.879778
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709816
 - hLp in component INaL (dimensionless): 0.452179
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622017
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697050
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936066
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330145
 - xs1 in component IKs (dimensionless): 0.239624
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:07:04 (465930): called boinc_finish(0)

</stderr_txt>
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