𝕏

Task 56004540

Name HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1
Workunit 26596755
Created 3 Jul 2024, 23:45:53 UTC
Sent 4 Jul 2024, 1:01:06 UTC
Report deadline 7 Jul 2024, 10:37:06 UTC
Received 8 Jul 2024, 2:01:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217799
Run time 1 hours 41 min 41 sec
CPU time 56 min 52 sec
Validate state Valid
Credit 72.30
Device peak FLOPS 5.48 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.59 MB
Peak swap size 391.84 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.264020
     * GNaL_b in INaL: 0.005451
     * Gto_b in Ito: 0.086428
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032044
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.159430
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.937847
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034032
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 53452645, states[0] = -95.015186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114755372, states[0] = -94.887889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173828577, states[0] = -94.948973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221630836, states[0] = -50.984141, states[40]= 0.000023
Saving checkpoint... 
Iteration: 276028874, states[0] = 18.732331, states[40]= 0.006182
Saving checkpoint... 
Iteration: 327118233, states[0] = -37.981698, states[40]= 0.000170
Saving checkpoint... 
Iteration: 383774813, states[0] = -94.905841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435076836, states[0] = -1.202238, states[40]= 0.004070
Saving checkpoint... 
Iteration: 458243875, states[0] = -94.868623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513583752, states[0] = -5.887130, states[40]= 0.003205
Saving checkpoint... 
Iteration: 543810218, states[0] = -94.936089, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.264020
     * GNaL_b in INaL: 0.005451
     * Gto_b in Ito: 0.086428
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032044
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.159430
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.937847
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034032
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 543810218
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.936089 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 599375032, states[0] = -94.970305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647507490, states[0] = 24.101859, states[40]= 0.094861
Saving checkpoint... 
Iteration: 697458263, states[0] = -94.992231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737026735, states[0] = 19.333468, states[40]= 0.006582
Saving checkpoint... 
Iteration: 738438976, states[0] = -94.988515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743727331, states[0] = -94.843227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763855490, states[0] = -94.962021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784987589, states[0] = -94.996645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800352489, states[0] = -94.960601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810968398, states[0] = -94.993845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828342491, states[0] = -94.955629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843985582, states[0] = -94.996339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866602750, states[0] = -23.078086, states[40]= 0.000787
Saving checkpoint... 
Iteration: 915884596, states[0] = -94.973581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936167504, states[0] = -94.084038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937055507, states[0] = 9.101493, states[40]= 0.004871
Saving checkpoint... 
Iteration: 938395480, states[0] = -94.977165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939703382, states[0] = -94.799048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950040401, states[0] = 14.921424, states[40]= 0.005188
Saving checkpoint... 
Iteration: 966636167, states[0] = -56.770906, states[40]= 0.000009
Saving checkpoint... 
Iteration: 979094493, states[0] = -15.208875, states[40]= 0.001435
Saving checkpoint... 
Iteration: 987575086, states[0] = -0.169563, states[40]= 0.004217
Saving checkpoint... 
Iteration: 998813887, states[0] = -94.938364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012978035, states[0] = -94.995174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024070399, states[0] = 2.369979, states[40]= 0.004503
Saving checkpoint... 
Iteration: 1032562325, states[0] = 6.201766, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1042218550, states[0] = -94.827926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050039224, states[0] = 15.344543, states[40]= 0.005242
Saving checkpoint... 
Iteration: 1059044855, states[0] = 13.274546, states[40]= 0.005042
Saving checkpoint... 
Iteration: 1069206069, states[0] = -94.804345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082820562, states[0] = -94.942753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090292372, states[0] = -94.921788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100266351, states[0] = -94.896348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111354194, states[0] = -94.961197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119470347, states[0] = -94.993950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128783487, states[0] = -94.913826, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.264020
     * GNaL_b in INaL: 0.005451
     * Gto_b in Ito: 0.086428
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032044
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.159430
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.937847
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034032
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1128783487
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.913826 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1179780155, states[0] = -94.910626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228232034, states[0] = -94.850499, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.264020
     * GNaL_b in INaL: 0.005451
     * Gto_b in Ito: 0.086428
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032044
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.159430
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.937847
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034032
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1228232034
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.850499 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1283977609, states[0] = -94.994936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330132523, states[0] = -52.789604, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1387510373, states[0] = 22.672527, states[40]= 0.048308
Saving checkpoint... 
Iteration: 1454813319, states[0] = -94.937674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528085309, states[0] = -95.108401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531765270, states[0] = -95.231555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532663051, states[0] = -95.230219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533696541, states[0] = -33.924131, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1547898783, states[0] = -95.151045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564700735, states[0] = -95.161960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596929260, states[0] = 17.218767, states[40]= 0.007140
Saving checkpoint... 
Iteration: 1603816064, states[0] = 21.716131, states[40]= 0.017025
Saving checkpoint... 
Iteration: 1606857932, states[0] = 2.537352, states[40]= 0.005111
Saving checkpoint... 
Iteration: 1620453805, states[0] = -95.027104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631512257, states[0] = -53.595940, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1643173150, states[0] = -9.685210, states[40]= 0.002712
Saving checkpoint... 
Iteration: 1657218767, states[0] = 20.929050, states[40]= 0.012254
Saving checkpoint... 
Iteration: 1667692917, states[0] = -95.281502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680434299, states[0] = -86.423795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726665976, states[0] = -95.091705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757153721, states[0] = 5.028822, states[40]= 0.005358
Saving checkpoint... 
Iteration: 1758153096, states[0] = -95.020079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759122647, states[0] = -95.208817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760311902, states[0] = -95.191784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763419772, states[0] = 20.620116, states[40]= 0.011155


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704014542593216_ORdGradInc_k_26-Pueyo_APDR-conf_973_1_r1505148483_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.264020
     * GNaL_b in INaL: 0.005451
     * Gto_b in Ito: 0.086428
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032044
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.159430
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.937847
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034032
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1763419772
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 20.620116 (After loading)
 - states[40]: 0.011155 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1812889354, states[0] = -95.022693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869989993, states[0] = -95.005473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927875058, states[0] = -94.971071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983694640, states[0] = -94.780368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038119919, states[0] = -39.653853, states[40]= 0.000134
Saving checkpoint... 
Iteration: 2084346566, states[0] = -94.956847, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.873165
 - CaMKt in component CaMK (millimolar): 0.006970
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.564267
 - nass in component intracellular_ions (millimolar): 6.564327
 - ki in component intracellular_ions (millimolar): 145.413194
 - kss in component intracellular_ions (millimolar): 145.413175
 - cansr in component intracellular_ions (millimolar): 1.311827
 - cajsr in component intracellular_ions (millimolar): 1.273951
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003629
 - hf in component INa (dimensionless): 0.879502
 - hs in component INa (dimensionless): 0.879497
 - j in component INa (dimensionless): 0.879468
 - hsp in component INa (dimensionless): 0.724891
 - jp in component INa (dimensionless): 0.879448
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709327
 - hLp in component INaL (dimensionless): 0.451629
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622144
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697234
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936678
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001600
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327996
 - xs1 in component IKs (dimensionless): 0.239040
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:01:28 (74831): called boinc_finish(0)

</stderr_txt>
]]>