𝕏

Task 56004107

Name HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_274_1
Workunit 26596545
Created 3 Jul 2024, 23:36:09 UTC
Sent 4 Jul 2024, 0:57:07 UTC
Report deadline 7 Jul 2024, 10:33:07 UTC
Received 5 Jul 2024, 7:07:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214641
Run time 2 hours 45 min 43 sec
CPU time 2 hours 45 min 43 sec
Validate state Valid
Credit 61.48
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.13 MB
Peak swap size 6.19 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_274.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_274_1_r493675278_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_274_1_r493675278_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.761355
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083290
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167794
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.328552
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035194
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12663057, states[0] = -94.416306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24787219, states[0] = -95.043067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37398407, states[0] = -95.081406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49207886, states[0] = -94.910554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61625028, states[0] = -43.798709, states[40]= 0.000074
Saving checkpoint... 
Iteration: 74170206, states[0] = -94.577986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86661655, states[0] = -91.205415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99030023, states[0] = 18.804596, states[40]= 0.006131
Saving checkpoint... 
Iteration: 111750204, states[0] = -94.954708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125432937, states[0] = -95.057742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138814748, states[0] = -95.011336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152228122, states[0] = -94.921343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165751686, states[0] = -94.953501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179528222, states[0] = 19.393089, states[40]= 0.006428
Saving checkpoint... 
Iteration: 192944233, states[0] = -95.057827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206792547, states[0] = -94.993795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220610361, states[0] = -28.429131, states[40]= 0.000547
Saving checkpoint... 
Iteration: 234122686, states[0] = -40.267684, states[40]= 0.000125
Saving checkpoint... 
Iteration: 247773833, states[0] = -94.976993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261415329, states[0] = -95.051206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275289247, states[0] = -94.990848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289148824, states[0] = -70.016609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302818821, states[0] = -95.012146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316139952, states[0] = -58.789182, states[40]= 0.000006
Saving checkpoint... 
Iteration: 329976853, states[0] = -95.062740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343827134, states[0] = -95.017063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357260866, states[0] = -94.963333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370786483, states[0] = -94.988423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384591076, states[0] = -10.531578, states[40]= 0.002221
Saving checkpoint... 
Iteration: 397975023, states[0] = -95.062435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411694770, states[0] = -94.860185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425524449, states[0] = 20.409763, states[40]= 0.007369
Saving checkpoint... 
Iteration: 438969492, states[0] = -95.061601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452832676, states[0] = -95.020077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466333394, states[0] = -95.020456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480016890, states[0] = 22.003244, states[40]= 0.013961
Saving checkpoint... 
Iteration: 493881678, states[0] = -95.041221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507752123, states[0] = -94.953049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521611048, states[0] = -29.066450, states[40]= 0.000516
Saving checkpoint... 
Iteration: 535453768, states[0] = -95.059004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547161759, states[0] = -90.670290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559686084, states[0] = -94.840626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572946229, states[0] = -95.057626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586444980, states[0] = -95.057384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600274991, states[0] = -94.977827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614102854, states[0] = -21.377070, states[40]= 0.000886
Saving checkpoint... 
Iteration: 627602623, states[0] = -21.160513, states[40]= 0.000898
Saving checkpoint... 
Iteration: 641472691, states[0] = -95.061948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655262477, states[0] = -94.964925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668738040, states[0] = -94.934505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682508566, states[0] = 24.020494, states[40]= 0.073809
Saving checkpoint... 
Iteration: 695954590, states[0] = -95.059047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709477880, states[0] = -95.062642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723010084, states[0] = 23.363620, states[40]= 0.051872
Saving checkpoint... 
Iteration: 736876805, states[0] = -95.039379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750717630, states[0] = -94.902747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764311073, states[0] = -95.006850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778104021, states[0] = -22.470672, states[40]= 0.000829
Saving checkpoint... 
Iteration: 791861151, states[0] = -95.033353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805266424, states[0] = -94.969070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818814469, states[0] = -95.009054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832326247, states[0] = -95.016247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845740526, states[0] = -94.937844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859580057, states[0] = -2.256863, states[40]= 0.003902
Saving checkpoint... 
Iteration: 873192321, states[0] = -94.854825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886552891, states[0] = 10.700889, states[40]= 0.004953
Saving checkpoint... 
Iteration: 900416741, states[0] = -95.051113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914272836, states[0] = -94.975532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928059872, states[0] = 7.861694, states[40]= 0.004857
Saving checkpoint... 
Iteration: 941863406, states[0] = -95.034179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955450006, states[0] = -95.058080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969252217, states[0] = -94.952877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983109632, states[0] = -27.733161, states[40]= 0.000581
Saving checkpoint... 
Iteration: 996973035, states[0] = -95.061778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010726676, states[0] = -94.917400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024363774, states[0] = -95.034276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038133923, states[0] = -52.033265, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1051919243, states[0] = -95.051624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065731997, states[0] = -94.925509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079551117, states[0] = 11.395954, states[40]= 0.004978
Saving checkpoint... 
Iteration: 1093391163, states[0] = -95.043930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106345144, states[0] = -95.026034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120171504, states[0] = -94.597145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134039939, states[0] = 15.582614, states[40]= 0.005283
Saving checkpoint... 
Iteration: 1147812031, states[0] = -95.007252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161490931, states[0] = -95.064063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174940202, states[0] = -95.056101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188412443, states[0] = -95.049862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201995625, states[0] = -95.064600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215734256, states[0] = -94.928747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229187673, states[0] = -94.844239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242866828, states[0] = -95.035350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256334937, states[0] = -95.020790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270060028, states[0] = 7.796042, states[40]= 0.004854
Saving checkpoint... 
Iteration: 1283813157, states[0] = -95.007910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296741930, states[0] = -94.939474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309608177, states[0] = -26.366054, states[40]= 0.000646
Saving checkpoint... 
Iteration: 1323059127, states[0] = 8.174103, states[40]= 0.004868
Saving checkpoint... 
Iteration: 1336870621, states[0] = -95.036746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350725143, states[0] = -94.914764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364588633, states[0] = -8.466248, states[40]= 0.002649
Saving checkpoint... 
Iteration: 1378188742, states[0] = -94.846670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391607938, states[0] = -26.141703, states[40]= 0.000657
Saving checkpoint... 
Iteration: 1405084008, states[0] = -4.910809, states[40]= 0.003404
Saving checkpoint... 
Iteration: 1418581642, states[0] = -3.281305, states[40]= 0.003721
Saving checkpoint... 
Iteration: 1431988479, states[0] = -95.063593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445542071, states[0] = 14.812183, states[40]= 0.005193
Saving checkpoint... 
Iteration: 1459396696, states[0] = -95.045377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472843579, states[0] = -95.025050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486269623, states[0] = -94.971959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499789115, states[0] = -94.989948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513092914, states[0] = -95.169162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526770771, states[0] = -5.025673, states[40]= 0.003791
Saving checkpoint... 
Iteration: 1540282205, states[0] = -16.798360, states[40]= 0.001386
Saving checkpoint... 
Iteration: 1554030173, states[0] = 17.398485, states[40]= 0.007123
Saving checkpoint... 
Iteration: 1567529756, states[0] = 17.514462, states[40]= 0.007188
Saving checkpoint... 
Iteration: 1581040585, states[0] = 12.576205, states[40]= 0.006066
Saving checkpoint... 
Iteration: 1594642050, states[0] = -93.558796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608152345, states[0] = -95.062496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620152392, states[0] = -95.064869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633389103, states[0] = -95.203063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646719326, states[0] = 21.222120, states[40]= 0.011870
Saving checkpoint... 
Iteration: 1660224373, states[0] = 19.518061, states[40]= 0.008547
Saving checkpoint... 
Iteration: 1673485458, states[0] = -21.360366, states[40]= 0.000940
Saving checkpoint... 
Iteration: 1686961318, states[0] = 1.023280, states[40]= 0.004941
Saving checkpoint... 
Iteration: 1700732221, states[0] = 16.364514, states[40]= 0.006817
Saving checkpoint... 
Iteration: 1714347786, states[0] = -94.882853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727705460, states[0] = 28.853287, states[40]= 0.122618
Saving checkpoint... 
Iteration: 1741113402, states[0] = -95.247571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754518493, states[0] = -59.256794, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1767929711, states[0] = 17.430030, states[40]= 0.007188
Saving checkpoint... 
Iteration: 1781739679, states[0] = 12.932406, states[40]= 0.006124
Saving checkpoint... 
Iteration: 1794863073, states[0] = -95.307336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807780806, states[0] = -95.029663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821177430, states[0] = -94.844211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834008490, states[0] = 23.910275, states[40]= 0.075377
Saving checkpoint... 
Iteration: 1847724521, states[0] = -94.930142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861549871, states[0] = 11.684579, states[40]= 0.005001
Saving checkpoint... 
Iteration: 1875366673, states[0] = -95.042078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889179793, states[0] = -94.820517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902600006, states[0] = -18.900537, states[40]= 0.001049
Saving checkpoint... 
Iteration: 1916021608, states[0] = 21.055534, states[40]= 0.008653
Saving checkpoint... 
Iteration: 1929474475, states[0] = -95.062823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943007543, states[0] = 24.724021, states[40]= 0.093034
Saving checkpoint... 
Iteration: 1956789582, states[0] = -94.990665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970612988, states[0] = -30.925765, states[40]= 0.000427
Saving checkpoint... 
Iteration: 1984081425, states[0] = -3.149075, states[40]= 0.003746
Saving checkpoint... 
Iteration: 1997837478, states[0] = -95.021806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011604320, states[0] = -22.758252, states[40]= 0.000815
Saving checkpoint... 
Iteration: 2025353330, states[0] = -95.029279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039181190, states[0] = -94.822208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052248319, states[0] = -94.947351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065942542, states[0] = -95.055978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079425561, states[0] = -95.052420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092869472, states[0] = -95.035801, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.940378
 - CaMKt in component CaMK (millimolar): 0.006941
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573522
 - nass in component intracellular_ions (millimolar): 6.573581
 - ki in component intracellular_ions (millimolar): 145.404947
 - kss in component intracellular_ions (millimolar): 145.404928
 - cansr in component intracellular_ions (millimolar): 1.308728
 - cajsr in component intracellular_ions (millimolar): 1.270700
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003604
 - hf in component INa (dimensionless): 0.880668
 - hs in component INa (dimensionless): 0.880663
 - j in component INa (dimensionless): 0.880635
 - hsp in component INa (dimensionless): 0.727089
 - jp in component INa (dimensionless): 0.880617
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710809
 - hLp in component INaL (dimensionless): 0.452785
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.620627
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.695377
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934371
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333176
 - xs1 in component IKs (dimensionless): 0.243284
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:25:31 (9252): called boinc_finish(0)

</stderr_txt>
]]>


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