𝕏

Task 56004104

Name HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174_0
Workunit 26596544
Created 3 Jul 2024, 23:36:09 UTC
Sent 4 Jul 2024, 0:57:07 UTC
Report deadline 7 Jul 2024, 10:33:07 UTC
Received 5 Jul 2024, 4:36:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214641
Run time 2 hours 45 min 5 sec
CPU time 2 hours 45 min 5 sec
Validate state Valid
Credit 62.48
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174_0_r1795320039_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174_0_r1795320039_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.158882
     * GNaL_b in INaL: 0.005794
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031557
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.163258
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.291260
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029131
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13835817, states[0] = -95.030516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27369430, states[0] = -95.014348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40973709, states[0] = -95.023715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54791606, states[0] = -94.939195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68541925, states[0] = 14.625905, states[40]= 0.005128
Saving checkpoint... 
Iteration: 82305430, states[0] = -94.938888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96164018, states[0] = -92.017541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110029605, states[0] = 18.880624, states[40]= 0.006027
Saving checkpoint... 
Iteration: 123920056, states[0] = -94.984754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137488882, states[0] = -94.996698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151337571, states[0] = -94.951915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164782243, states[0] = -94.911060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178350395, states[0] = -94.957900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192236150, states[0] = -94.854513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206055995, states[0] = 9.423663, states[40]= 0.004888
Saving checkpoint... 
Iteration: 219906002, states[0] = -94.978497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233589723, states[0] = -9.484302, states[40]= 0.002440
Saving checkpoint... 
Iteration: 247266086, states[0] = -94.893551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260810341, states[0] = -94.933583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274685241, states[0] = -94.753334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287852962, states[0] = -94.958562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300955102, states[0] = -94.989626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313614683, states[0] = -32.525638, states[40]= 0.000363
Saving checkpoint... 
Iteration: 327112393, states[0] = -30.371436, states[40]= 0.000461
Saving checkpoint... 
Iteration: 340578100, states[0] = -1.126885, states[40]= 0.004089
Saving checkpoint... 
Iteration: 354143802, states[0] = -62.787578, states[40]= 0.000003
Saving checkpoint... 
Iteration: 367704967, states[0] = -94.799070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381587824, states[0] = -7.911046, states[40]= 0.002774
Saving checkpoint... 
Iteration: 395452927, states[0] = -94.989150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409153899, states[0] = -76.693210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423050606, states[0] = 11.559213, states[40]= 0.004947
Saving checkpoint... 
Iteration: 436897616, states[0] = -94.975693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450399182, states[0] = -94.976167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463783201, states[0] = -94.910990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477657175, states[0] = -82.263511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491083672, states[0] = -4.759707, states[40]= 0.003441
Saving checkpoint... 
Iteration: 504734809, states[0] = -94.851895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518423865, states[0] = -94.982872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532255893, states[0] = -94.881209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545680634, states[0] = -94.728482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559568095, states[0] = 4.163650, states[40]= 0.004658
Saving checkpoint... 
Iteration: 573317231, states[0] = -94.938111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585269098, states[0] = -94.896588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598615941, states[0] = -33.713439, states[40]= 0.000314
Saving checkpoint... 
Iteration: 611521077, states[0] = 21.085229, states[40]= 0.008663
Saving checkpoint... 
Iteration: 625104340, states[0] = -22.848716, states[40]= 0.000818
Saving checkpoint... 
Iteration: 638725771, states[0] = -94.837234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651870441, states[0] = -94.965928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664748840, states[0] = -94.871993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677327616, states[0] = -94.944666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689354575, states[0] = -94.959030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702867099, states[0] = -94.964531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715279767, states[0] = -94.907520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729170756, states[0] = -94.305227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742763402, states[0] = -94.890087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756652863, states[0] = -75.028378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770541688, states[0] = 14.906034, states[40]= 0.005135
Saving checkpoint... 
Iteration: 784111159, states[0] = -29.213955, states[40]= 0.000517
Saving checkpoint... 
Iteration: 797639531, states[0] = -57.893191, states[40]= 0.000008
Saving checkpoint... 
Iteration: 809657523, states[0] = -82.863130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822562393, states[0] = 6.748886, states[40]= 0.004799
Saving checkpoint... 
Iteration: 834638640, states[0] = -56.904566, states[40]= 0.000009
Saving checkpoint... 
Iteration: 848174419, states[0] = -94.599206, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174_0_r1795320039_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_174_0_r1795320039_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.158882
     * GNaL_b in INaL: 0.005794
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031557
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.163258
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.291260
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029131
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 848174419
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.599206 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 862022435, states[0] = 20.791986, states[40]= 0.007906
Saving checkpoint... 
Iteration: 875936076, states[0] = -94.985440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889632693, states[0] = -50.467767, states[40]= 0.000026
Saving checkpoint... 
Iteration: 903412178, states[0] = -94.979609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917274182, states[0] = -94.901765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931034930, states[0] = 17.257343, states[40]= 0.005485
Saving checkpoint... 
Iteration: 944402755, states[0] = -94.976910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958285757, states[0] = -94.913037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971231199, states[0] = -94.845910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985069704, states[0] = 3.389013, states[40]= 0.004600
Saving checkpoint... 
Iteration: 998707235, states[0] = -94.803136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011154224, states[0] = -77.226198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024639164, states[0] = -57.484761, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1038520534, states[0] = 21.196796, states[40]= 0.009038
Saving checkpoint... 
Iteration: 1052320052, states[0] = -94.939655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065780077, states[0] = -94.907586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079632754, states[0] = -50.532481, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1092764668, states[0] = -94.891304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106295706, states[0] = -94.921644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119985416, states[0] = -94.993857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133543668, states[0] = 14.181796, states[40]= 0.005075
Saving checkpoint... 
Iteration: 1147436325, states[0] = -94.985311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161230968, states[0] = -94.845412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175050865, states[0] = 11.459027, states[40]= 0.004944
Saving checkpoint... 
Iteration: 1188874344, states[0] = -94.967103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202726321, states[0] = -94.837774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216597715, states[0] = -16.664595, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1228854145, states[0] = -94.958465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241340263, states[0] = -94.951495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254445905, states[0] = -94.987224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268213730, states[0] = -94.815415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282100020, states[0] = -18.815315, states[40]= 0.001061
Saving checkpoint... 
Iteration: 1295540799, states[0] = 15.226855, states[40]= 0.005167
Saving checkpoint... 
Iteration: 1309410757, states[0] = -94.978948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321534152, states[0] = 17.513088, states[40]= 0.005546
Saving checkpoint... 
Iteration: 1335093471, states[0] = -12.762262, states[40]= 0.001811
Saving checkpoint... 
Iteration: 1347877916, states[0] = -94.968355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361782013, states[0] = -94.909254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374065256, states[0] = 5.479213, states[40]= 0.004738
Saving checkpoint... 
Iteration: 1387745333, states[0] = -94.866716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401605495, states[0] = -23.925037, states[40]= 0.000768
Saving checkpoint... 
Iteration: 1414818818, states[0] = -94.938600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428604982, states[0] = -23.446798, states[40]= 0.000790
Saving checkpoint... 
Iteration: 1442389951, states[0] = -94.972546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456252057, states[0] = -94.875702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470017462, states[0] = 21.766684, states[40]= 0.012450
Saving checkpoint... 
Iteration: 1483842742, states[0] = -94.952644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497748860, states[0] = -94.871456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511177372, states[0] = -10.376953, states[40]= 0.002513
Saving checkpoint... 
Iteration: 1524869062, states[0] = -95.218102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537556390, states[0] = 4.529270, states[40]= 0.005306
Saving checkpoint... 
Iteration: 1551274627, states[0] = -95.241316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565074940, states[0] = -95.246751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578586049, states[0] = -95.258882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592431879, states[0] = 16.506601, states[40]= 0.006733
Saving checkpoint... 
Iteration: 1605964091, states[0] = -0.848526, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1617970198, states[0] = -5.694688, states[40]= 0.003669
Saving checkpoint... 
Iteration: 1631494028, states[0] = -30.641472, states[40]= 0.000437
Saving checkpoint... 
Iteration: 1645204928, states[0] = 29.648199, states[40]= 0.133539
Saving checkpoint... 
Iteration: 1658729504, states[0] = 17.461728, states[40]= 0.007065
Saving checkpoint... 
Iteration: 1672223993, states[0] = 19.571432, states[40]= 0.008437
Saving checkpoint... 
Iteration: 1686077902, states[0] = -13.289835, states[40]= 0.001952
Saving checkpoint... 
Iteration: 1698665329, states[0] = -1.814259, states[40]= 0.004494
Saving checkpoint... 
Iteration: 1711509260, states[0] = 24.206702, states[40]= 0.061775
Saving checkpoint... 
Iteration: 1725330867, states[0] = 16.890956, states[40]= 0.006862
Saving checkpoint... 
Iteration: 1738696609, states[0] = -95.150913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752221622, states[0] = -95.194693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765850585, states[0] = 7.341117, states[40]= 0.005554
Saving checkpoint... 
Iteration: 1778849532, states[0] = -94.850682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791231541, states[0] = -95.208937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804079505, states[0] = -4.309382, states[40]= 0.003661
Saving checkpoint... 
Iteration: 1816781006, states[0] = -94.948766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829117153, states[0] = -36.678960, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1841982808, states[0] = -95.013192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854655178, states[0] = -80.589728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867270095, states[0] = -94.906436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880048130, states[0] = 12.403547, states[40]= 0.004984
Saving checkpoint... 
Iteration: 1892381116, states[0] = -94.973654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905995509, states[0] = -94.997619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919187454, states[0] = -94.761316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932712095, states[0] = -94.813241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945562291, states[0] = 6.773779, states[40]= 0.004801
Saving checkpoint... 
Iteration: 1958680408, states[0] = -94.726493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971536133, states[0] = 16.849478, states[40]= 0.005402
Saving checkpoint... 
Iteration: 1984182771, states[0] = -94.741813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996601263, states[0] = -19.987979, states[40]= 0.000976
Saving checkpoint... 
Iteration: 2008987317, states[0] = -94.993602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021073503, states[0] = 1.454979, states[40]= 0.004421
Saving checkpoint... 
Iteration: 2033500114, states[0] = -80.980937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045847715, states[0] = -94.954795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057788604, states[0] = -94.914851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069978461, states[0] = -94.992199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082485624, states[0] = -94.993194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096290778, states[0] = -94.916723, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.870883
 - CaMKt in component CaMK (millimolar): 0.007098
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.593076
 - nass in component intracellular_ions (millimolar): 6.593136
 - ki in component intracellular_ions (millimolar): 145.382510
 - kss in component intracellular_ions (millimolar): 145.382491
 - cansr in component intracellular_ions (millimolar): 1.319529
 - cajsr in component intracellular_ions (millimolar): 1.281337
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879462
 - hs in component INa (dimensionless): 0.879458
 - j in component INa (dimensionless): 0.879428
 - hsp in component INa (dimensionless): 0.724816
 - jp in component INa (dimensionless): 0.879408
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708763
 - hLp in component INaL (dimensionless): 0.450082
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619762
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694343
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934648
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330931
 - xs1 in component IKs (dimensionless): 0.242965
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:46:32 (2392): called boinc_finish(0)

</stderr_txt>
]]>


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