𝕏

Task 56003985

Name HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_151_1
Workunit 26596484
Created 3 Jul 2024, 23:36:04 UTC
Sent 4 Jul 2024, 0:57:07 UTC
Report deadline 7 Jul 2024, 10:33:07 UTC
Received 5 Jul 2024, 1:44:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214641
Run time 2 hours 46 min
CPU time 2 hours 45 min 35 sec
Validate state Valid
Credit 62.40
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.21 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_151.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_151_1_r2021501735_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013558363453_ORdGradInc_k_26-Pueyo_APDR-conf_151_1_r2021501735_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.852969
     * GNaL_b in INaL: 0.005578
     * Gto_b in Ito: 0.084042
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032071
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.160331
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.298009
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034453
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13816421, states[0] = -95.037561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27542960, states[0] = 13.397812, states[40]= 0.005128
Saving checkpoint... 
Iteration: 41299212, states[0] = -94.968440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53678472, states[0] = -94.763792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67249510, states[0] = -94.897988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80777114, states[0] = -94.924054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94245804, states[0] = -94.884095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107833579, states[0] = -94.960642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121684000, states[0] = -94.764401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135093167, states[0] = -13.736839, states[40]= 0.001651
Saving checkpoint... 
Iteration: 148913580, states[0] = -94.988682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162392976, states[0] = -94.982247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176220283, states[0] = -94.837961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189653877, states[0] = -80.109100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203197814, states[0] = -94.794536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217070460, states[0] = 2.525571, states[40]= 0.004525
Saving checkpoint... 
Iteration: 230958144, states[0] = -94.996933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244825114, states[0] = -94.950958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258403030, states[0] = -94.984359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272285213, states[0] = -94.920998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286084024, states[0] = -5.822518, states[40]= 0.003220
Saving checkpoint... 
Iteration: 298549350, states[0] = 11.738681, states[40]= 0.004977
Saving checkpoint... 
Iteration: 311958965, states[0] = -94.996909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325509994, states[0] = 23.118453, states[40]= 0.052422
Saving checkpoint... 
Iteration: 339393428, states[0] = -94.981343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352796181, states[0] = -94.930356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366243975, states[0] = -94.874227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380134331, states[0] = -54.422640, states[40]= 0.000013
Saving checkpoint... 
Iteration: 394022116, states[0] = 20.731134, states[40]= 0.008221
Saving checkpoint... 
Iteration: 407544436, states[0] = 13.623466, states[40]= 0.005080
Saving checkpoint... 
Iteration: 421307078, states[0] = -94.938712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435005774, states[0] = 26.606458, states[40]= 0.132229
Saving checkpoint... 
Iteration: 448783705, states[0] = -94.919465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462602298, states[0] = -22.298043, states[40]= 0.000827
Saving checkpoint... 
Iteration: 476470528, states[0] = -94.998675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490174620, states[0] = -94.670351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502746016, states[0] = -94.876939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516128585, states[0] = -48.217905, states[40]= 0.000036
Saving checkpoint... 
Iteration: 529997768, states[0] = -95.002338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543699061, states[0] = -94.796613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557299547, states[0] = -94.932916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571023208, states[0] = 20.476764, states[40]= 0.007708
Saving checkpoint... 
Iteration: 584466658, states[0] = -94.997999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598042298, states[0] = 14.423467, states[40]= 0.005146
Saving checkpoint... 
Iteration: 611626548, states[0] = -46.066728, states[40]= 0.000051
Saving checkpoint... 
Iteration: 625434097, states[0] = -94.991885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639079558, states[0] = -2.684846, states[40]= 0.003832
Saving checkpoint... 
Iteration: 652480000, states[0] = -94.999959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665962402, states[0] = -94.997253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679737477, states[0] = -94.864707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693235182, states[0] = -94.861261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707017044, states[0] = 21.744355, states[40]= 0.013409
Saving checkpoint... 
Iteration: 720411530, states[0] = -94.986376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732827368, states[0] = -94.951923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746595802, states[0] = -16.103805, states[40]= 0.001322
Saving checkpoint... 
Iteration: 760112970, states[0] = -32.508024, states[40]= 0.000350
Saving checkpoint... 
Iteration: 773661031, states[0] = -90.708323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786992462, states[0] = -95.001527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800621910, states[0] = -41.291041, states[40]= 0.000106
Saving checkpoint... 
Iteration: 814480436, states[0] = -94.999916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828126226, states[0] = -45.729329, states[40]= 0.000054
Saving checkpoint... 
Iteration: 841970379, states[0] = -94.998419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855806518, states[0] = -94.938023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869655217, states[0] = -82.343778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883180816, states[0] = -94.746783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896783687, states[0] = -94.919161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910109969, states[0] = -29.624323, states[40]= 0.000479
Saving checkpoint... 
Iteration: 923796026, states[0] = -94.929860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937213479, states[0] = -94.824592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951032087, states[0] = 17.976512, states[40]= 0.005804
Saving checkpoint... 
Iteration: 964848479, states[0] = -94.963166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978722394, states[0] = -94.840453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992583360, states[0] = -5.325229, states[40]= 0.003324
Saving checkpoint... 
Iteration: 1006446770, states[0] = -94.994234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020189938, states[0] = -94.776586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033622148, states[0] = -41.531586, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1046884240, states[0] = -94.977841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060150036, states[0] = -73.836214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073860291, states[0] = -94.968526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087172642, states[0] = -94.603335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100962517, states[0] = -94.996994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114654296, states[0] = -80.769612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128425475, states[0] = -94.989616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142291428, states[0] = -94.925882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155919462, states[0] = -94.988145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169550637, states[0] = 11.234844, states[40]= 0.004957
Saving checkpoint... 
Iteration: 1183144912, states[0] = -66.715899, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1196736434, states[0] = -94.862821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210460209, states[0] = -94.996536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224052209, states[0] = 10.612269, states[40]= 0.004935
Saving checkpoint... 
Iteration: 1237800719, states[0] = -94.933396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251259206, states[0] = -94.893226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264806289, states[0] = -94.937592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278423781, states[0] = -94.989119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291948025, states[0] = -94.994291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305786898, states[0] = -94.921817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319644588, states[0] = -66.303257, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1333164876, states[0] = -93.305419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347017979, states[0] = 21.577450, states[40]= 0.011899
Saving checkpoint... 
Iteration: 1360923027, states[0] = -94.988885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374675021, states[0] = -94.679254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388519920, states[0] = 21.203429, states[40]= 0.009718
Saving checkpoint... 
Iteration: 1402385481, states[0] = -94.978040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415818569, states[0] = -94.945998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429455085, states[0] = -94.995504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442859494, states[0] = -94.967942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456258763, states[0] = -94.892567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469938338, states[0] = -94.992247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483570115, states[0] = 2.705885, states[40]= 0.004541
Saving checkpoint... 
Iteration: 1497024641, states[0] = 20.123790, states[40]= 0.007187
Saving checkpoint... 
Iteration: 1510720728, states[0] = -95.159363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524514363, states[0] = -95.163947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538331643, states[0] = -95.201342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552046234, states[0] = -94.584110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564656221, states[0] = -95.042484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578326395, states[0] = 18.597945, states[40]= 0.007799
Saving checkpoint... 
Iteration: 1591711232, states[0] = -95.189191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605507118, states[0] = -95.183572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619163583, states[0] = -1.058955, states[40]= 0.004617
Saving checkpoint... 
Iteration: 1632929949, states[0] = 17.108826, states[40]= 0.007064
Saving checkpoint... 
Iteration: 1646637293, states[0] = -95.230595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660013149, states[0] = -54.269877, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1673649306, states[0] = -95.245117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687343694, states[0] = -94.283990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700699315, states[0] = -95.287763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714179696, states[0] = -95.273770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727627301, states[0] = -95.217852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741349499, states[0] = -94.929973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754812357, states[0] = -53.322581, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1768317194, states[0] = -59.352306, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1781758737, states[0] = 2.192163, states[40]= 0.005082
Saving checkpoint... 
Iteration: 1795388663, states[0] = -95.150024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809171506, states[0] = -94.720745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822754355, states[0] = -94.923430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836227330, states[0] = -94.873336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849627047, states[0] = -47.721886, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1863106564, states[0] = -27.000947, states[40]= 0.000603
Saving checkpoint... 
Iteration: 1876904388, states[0] = -94.991024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890455662, states[0] = -95.000217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903944481, states[0] = -94.996486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917670733, states[0] = -94.503847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931066395, states[0] = 4.488156, states[40]= 0.004680
Saving checkpoint... 
Iteration: 1944806353, states[0] = -94.938150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958308749, states[0] = -94.939552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972041808, states[0] = 14.598683, states[40]= 0.005163
Saving checkpoint... 
Iteration: 1985442767, states[0] = -94.993066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998887698, states[0] = -94.978554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012532340, states[0] = 17.894225, states[40]= 0.005777
Saving checkpoint... 
Iteration: 2025865888, states[0] = -94.970317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039610743, states[0] = -30.369412, states[40]= 0.000444
Saving checkpoint... 
Iteration: 2053403828, states[0] = -94.983369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067101898, states[0] = -21.916913, states[40]= 0.000847
Saving checkpoint... 
Iteration: 2080736596, states[0] = -94.862456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094534067, states[0] = 17.332013, states[40]= 0.005613
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.877426
 - CaMKt in component CaMK (millimolar): 0.006944
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.552469
 - nass in component intracellular_ions (millimolar): 6.552529
 - ki in component intracellular_ions (millimolar): 145.425531
 - kss in component intracellular_ions (millimolar): 145.425511
 - cansr in component intracellular_ions (millimolar): 1.309838
 - cajsr in component intracellular_ions (millimolar): 1.271955
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003627
 - hf in component INa (dimensionless): 0.879576
 - hs in component INa (dimensionless): 0.879572
 - j in component INa (dimensionless): 0.879543
 - hsp in component INa (dimensionless): 0.725031
 - jp in component INa (dimensionless): 0.879523
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709406
 - hLp in component INaL (dimensionless): 0.451658
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621857
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696811
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935903
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329061
 - xs1 in component IKs (dimensionless): 0.240113
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:42:53 (8620): called boinc_finish(0)

</stderr_txt>
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