𝕏

Task 56003656

Name HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773_0
Workunit 26596320
Created 3 Jul 2024, 23:35:53 UTC
Sent 4 Jul 2024, 0:55:27 UTC
Report deadline 7 Jul 2024, 10:31:27 UTC
Received 5 Jul 2024, 1:15:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232696
Run time 2 hours 53 min 58 sec
CPU time 1 hours 7 min 19 sec
Validate state Valid
Credit 60.58
Device peak FLOPS 3.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.32 MB
Peak swap size 6.30 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773_0_r301880723_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773_0_r301880723_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.259655
     * GNaL_b in INaL: 0.005505
     * Gto_b in Ito: 0.086746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031984
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.164612
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.604201
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032850
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12704749, states[0] = -94.929760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22958562, states[0] = -95.076612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31587123, states[0] = -10.287419, states[40]= 0.002285
Saving checkpoint... 
Iteration: 47065715, states[0] = 4.157800, states[40]= 0.004647
Saving checkpoint... 
Iteration: 64120780, states[0] = -40.898297, states[40]= 0.000112
Saving checkpoint... 
Iteration: 77007918, states[0] = 23.579287, states[40]= 0.085794
Saving checkpoint... 
Iteration: 86768703, states[0] = -94.932546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95676207, states[0] = -94.740991, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773_0_r301880723_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704013542849181_ORdGradInc_k_26-Pueyo_APDR-conf_773_0_r301880723_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.259655
     * GNaL_b in INaL: 0.005505
     * Gto_b in Ito: 0.086746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031984
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.164612
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.604201
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032850
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 95676207
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.740991 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 108799323, states[0] = -94.956354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120949176, states[0] = -95.016441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133537980, states[0] = 15.788616, states[40]= 0.005265
Saving checkpoint... 
Iteration: 150726851, states[0] = -94.869888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167489196, states[0] = -95.020384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184717770, states[0] = -94.853698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198649441, states[0] = -72.570232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210126347, states[0] = -45.507523, states[40]= 0.000056
Saving checkpoint... 
Iteration: 232916457, states[0] = -95.006346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245971428, states[0] = -95.017177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259868487, states[0] = -94.990965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275787881, states[0] = -94.942493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286598863, states[0] = -18.877342, states[40]= 0.001044
Saving checkpoint... 
Iteration: 298385346, states[0] = -94.997084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305202442, states[0] = -94.824354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318608600, states[0] = -28.098089, states[40]= 0.000552
Saving checkpoint... 
Iteration: 333521035, states[0] = 20.698870, states[40]= 0.008700
Saving checkpoint... 
Iteration: 342428468, states[0] = -95.009042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353514379, states[0] = 21.846540, states[40]= 0.020315
Saving checkpoint... 
Iteration: 366945076, states[0] = -95.012502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382980479, states[0] = -95.018328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391210725, states[0] = -94.840294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414936964, states[0] = -95.010837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426933926, states[0] = -95.010185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436492648, states[0] = -95.019888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441834616, states[0] = -94.974940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452128176, states[0] = -47.405727, states[40]= 0.000041
Saving checkpoint... 
Iteration: 465706660, states[0] = -94.832512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480870051, states[0] = -94.991386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492334980, states[0] = -94.975106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503458130, states[0] = -95.014791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514200617, states[0] = -94.820543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532905503, states[0] = -95.003124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547006726, states[0] = 24.699479, states[40]= 0.111600
Saving checkpoint... 
Iteration: 561520761, states[0] = 20.755203, states[40]= 0.008887
Saving checkpoint... 
Iteration: 578332795, states[0] = -94.973842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585555792, states[0] = 9.070784, states[40]= 0.004846
Saving checkpoint... 
Iteration: 601125763, states[0] = -44.887260, states[40]= 0.000061
Saving checkpoint... 
Iteration: 616203981, states[0] = -94.827184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636275562, states[0] = -94.930766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652884508, states[0] = -94.996551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671349778, states[0] = -94.982526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682095248, states[0] = -15.463217, states[40]= 0.001397
Saving checkpoint... 
Iteration: 699204764, states[0] = -94.828668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710368836, states[0] = -94.990758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719070909, states[0] = 2.270262, states[40]= 0.004476
Saving checkpoint... 
Iteration: 728818251, states[0] = -94.965012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747375843, states[0] = -94.993412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763244687, states[0] = -94.894729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776203610, states[0] = -94.826346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785151426, states[0] = -75.623810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795741644, states[0] = -94.890510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806017970, states[0] = 21.279298, states[40]= 0.011716
Saving checkpoint... 
Iteration: 820663316, states[0] = -92.566295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835073671, states[0] = 0.813409, states[40]= 0.004323
Saving checkpoint... 
Iteration: 850030976, states[0] = 18.120035, states[40]= 0.005836
Saving checkpoint... 
Iteration: 864788553, states[0] = -94.942658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878910840, states[0] = -95.004354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898624891, states[0] = -43.988625, states[40]= 0.000070
Saving checkpoint... 
Iteration: 908485484, states[0] = -95.018660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916481988, states[0] = -95.018183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928841506, states[0] = -94.978276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946457658, states[0] = -95.014418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951601764, states[0] = -21.623990, states[40]= 0.000863
Saving checkpoint... 
Iteration: 961466469, states[0] = -95.015864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983848701, states[0] = -94.981807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994700815, states[0] = -94.820623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000646988, states[0] = -69.030409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012271575, states[0] = -94.926489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028280311, states[0] = -94.935095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050894789, states[0] = -94.999628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062449179, states[0] = -95.012822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071376266, states[0] = -94.993354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080772037, states[0] = -94.926919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094167760, states[0] = -94.173743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105796941, states[0] = -94.949473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121069332, states[0] = 3.062451, states[40]= 0.004546
Saving checkpoint... 
Iteration: 1139437618, states[0] = -95.010496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154184568, states[0] = -94.783736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171927187, states[0] = -95.008200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183681117, states[0] = -94.770645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198572767, states[0] = 1.300988, states[40]= 0.004378
Saving checkpoint... 
Iteration: 1215159758, states[0] = -89.252965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233183195, states[0] = -94.779185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247682949, states[0] = -94.778290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261886889, states[0] = -94.996952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276151669, states[0] = -76.016980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289865585, states[0] = -94.989071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308329390, states[0] = -94.971426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320570528, states[0] = 2.464246, states[40]= 0.004494
Saving checkpoint... 
Iteration: 1328831838, states[0] = -94.972809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337321091, states[0] = -94.966414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350974834, states[0] = -95.016884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359585256, states[0] = -6.727054, states[40]= 0.003015
Saving checkpoint... 
Iteration: 1371339944, states[0] = -94.977176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386666074, states[0] = -93.780150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400213073, states[0] = -94.843975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411848116, states[0] = -94.981244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424368798, states[0] = -94.990272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440459117, states[0] = -95.014342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446854040, states[0] = -94.983994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459275905, states[0] = -94.930561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475195247, states[0] = -94.808848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488969757, states[0] = -95.016031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508785620, states[0] = -19.955770, states[40]= 0.001024
Saving checkpoint... 
Iteration: 1521062596, states[0] = 0.520884, states[40]= 0.004803
Saving checkpoint... 
Iteration: 1536960750, states[0] = 1.350613, states[40]= 0.004935
Saving checkpoint... 
Iteration: 1544021571, states[0] = -95.202054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556284561, states[0] = -95.140413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581964114, states[0] = -1.428696, states[40]= 0.004530
Saving checkpoint... 
Iteration: 1594368343, states[0] = -95.110192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604479508, states[0] = -16.015706, states[40]= 0.001493
Saving checkpoint... 
Iteration: 1621251238, states[0] = 6.549458, states[40]= 0.005459
Saving checkpoint... 
Iteration: 1634777338, states[0] = -13.738816, states[40]= 0.001861
Saving checkpoint... 
Iteration: 1647233875, states[0] = -95.236570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659334877, states[0] = 14.757260, states[40]= 0.006373
Saving checkpoint... 
Iteration: 1669979468, states[0] = -95.140868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679651685, states[0] = -95.257742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693937682, states[0] = -91.003782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703507493, states[0] = -47.303458, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1719412144, states[0] = -52.915674, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1735722408, states[0] = -95.221340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749216950, states[0] = -95.213109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760876049, states[0] = -95.132981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768423436, states[0] = -95.222829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783810711, states[0] = 23.156498, states[40]= 0.045095
Saving checkpoint... 
Iteration: 1796365809, states[0] = -95.271672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814923307, states[0] = -95.050172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830012694, states[0] = 21.912353, states[40]= 0.028190
Saving checkpoint... 
Iteration: 1838667541, states[0] = -94.403202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854109879, states[0] = -30.140637, states[40]= 0.000454
Saving checkpoint... 
Iteration: 1868561997, states[0] = 6.268004, states[40]= 0.004753
Saving checkpoint... 
Iteration: 1880893541, states[0] = -95.004917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891424585, states[0] = -95.011652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913018483, states[0] = 21.168691, states[40]= 0.011024
Saving checkpoint... 
Iteration: 1932656664, states[0] = -84.748731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947796758, states[0] = -94.949580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963333043, states[0] = -94.973553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972086336, states[0] = -7.599668, states[40]= 0.002829
Saving checkpoint... 
Iteration: 1985736054, states[0] = -94.881895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000369061, states[0] = -94.990119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011168728, states[0] = -94.326019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023552237, states[0] = 10.492484, states[40]= 0.004888
Saving checkpoint... 
Iteration: 2031836923, states[0] = -94.975156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043180220, states[0] = -94.765341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058080465, states[0] = -3.272022, states[40]= 0.003709
Saving checkpoint... 
Iteration: 2076555201, states[0] = 9.310535, states[40]= 0.004853
Saving checkpoint... 
Iteration: 2083532012, states[0] = 17.799713, states[40]= 0.005720
Saving checkpoint... 
Iteration: 2095677364, states[0] = -94.742421, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.895498
 - CaMKt in component CaMK (millimolar): 0.006986
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.553373
 - nass in component intracellular_ions (millimolar): 6.553433
 - ki in component intracellular_ions (millimolar): 145.424008
 - kss in component intracellular_ions (millimolar): 145.423989
 - cansr in component intracellular_ions (millimolar): 1.311743
 - cajsr in component intracellular_ions (millimolar): 1.273774
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879890
 - hs in component INa (dimensionless): 0.879886
 - j in component INa (dimensionless): 0.879857
 - hsp in component INa (dimensionless): 0.725623
 - jp in component INa (dimensionless): 0.879838
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709851
 - hLp in component INaL (dimensionless): 0.452115
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621727
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696821
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936393
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001598
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326121
 - xs1 in component IKs (dimensionless): 0.239968
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:05:49 (15340): called boinc_finish(0)

</stderr_txt>
]]>


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