𝕏

Task 56003080

Name HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_258_1
Workunit 26596047
Created 3 Jul 2024, 23:26:09 UTC
Sent 4 Jul 2024, 0:50:02 UTC
Report deadline 7 Jul 2024, 10:26:02 UTC
Received 4 Jul 2024, 9:45:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236853
Run time 2 hours 50 min 12 sec
CPU time 2 hours 50 min 5 sec
Validate state Valid
Credit 61.22
Device peak FLOPS 3.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.23 MB
Peak swap size 2.52 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_258.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_258_1_r1626765063_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_258_1_r1626765063_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.733107
     * GNaL_b in INaL: 0.005728
     * Gto_b in Ito: 0.085533
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031738
     * GKs_b in IKs: 0.001953
     * GK1_b in IK1: 0.165066
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.611200
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030760
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13172888, states[0] = -94.836137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26350379, states[0] = -95.044092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39529335, states[0] = 18.515781, states[40]= 0.006062
Saving checkpoint... 
Iteration: 52707585, states[0] = -94.867505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65886683, states[0] = -95.024665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79033062, states[0] = 17.618165, states[40]= 0.005647
Saving checkpoint... 
Iteration: 92192362, states[0] = -94.821640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105353503, states[0] = -95.002037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118510764, states[0] = 22.773483, states[40]= 0.043929
Saving checkpoint... 
Iteration: 131427448, states[0] = -95.024308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144556348, states[0] = 9.115022, states[40]= 0.004877
Saving checkpoint... 
Iteration: 157665785, states[0] = -93.502864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170833873, states[0] = -94.988371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184005372, states[0] = 27.261639, states[40]= 0.143410
Saving checkpoint... 
Iteration: 197204506, states[0] = -94.840615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210389653, states[0] = -95.012022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225040424, states[0] = 15.229441, states[40]= 0.005186
Saving checkpoint... 
Iteration: 226192376, states[0] = -94.815296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239299988, states[0] = -94.965348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252482416, states[0] = -95.032233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265667726, states[0] = -94.051674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278850841, states[0] = -94.996430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292033553, states[0] = 17.579596, states[40]= 0.005608
Saving checkpoint... 
Iteration: 305218527, states[0] = -94.866506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318402975, states[0] = -95.015871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331585132, states[0] = -6.126574, states[40]= 0.003156
Saving checkpoint... 
Iteration: 344767110, states[0] = -94.934784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357950197, states[0] = -95.026912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371135006, states[0] = -53.865272, states[40]= 0.000015
Saving checkpoint... 
Iteration: 384326188, states[0] = -94.983150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385557042, states[0] = 8.857252, states[40]= 0.004869
Saving checkpoint... 
Iteration: 398684303, states[0] = -94.794371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411862817, states[0] = -95.001677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425041508, states[0] = 14.840840, states[40]= 0.005144
Saving checkpoint... 
Iteration: 438215662, states[0] = -94.861287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451390668, states[0] = -95.011997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464562115, states[0] = 6.715272, states[40]= 0.004793
Saving checkpoint... 
Iteration: 477732039, states[0] = -94.888782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490907433, states[0] = -95.017013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504083347, states[0] = -4.810856, states[40]= 0.003429
Saving checkpoint... 
Iteration: 517261018, states[0] = -94.927821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530437046, states[0] = -95.024182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543612517, states[0] = -31.068921, states[40]= 0.000423
Saving checkpoint... 
Iteration: 556785748, states[0] = -94.953114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569955825, states[0] = -95.027793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583135941, states[0] = -54.892459, states[40]= 0.000013
Saving checkpoint... 
Iteration: 596321236, states[0] = -94.979956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609494679, states[0] = -95.033538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622666980, states[0] = -93.866031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635890832, states[0] = -95.011927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642872235, states[0] = -95.005330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655875645, states[0] = -95.006618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668841344, states[0] = -94.991434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681895280, states[0] = -95.013310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694859740, states[0] = -95.000169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707824288, states[0] = -94.981780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720786667, states[0] = -94.953828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733893932, states[0] = -95.012854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747021823, states[0] = 20.797913, states[40]= 0.008268
Saving checkpoint... 
Iteration: 760139384, states[0] = -58.743864, states[40]= 0.000006
Saving checkpoint... 
Iteration: 773100674, states[0] = -19.903351, states[40]= 0.000977
Saving checkpoint... 
Iteration: 786061910, states[0] = 6.804494, states[40]= 0.004797
Saving checkpoint... 
Iteration: 799020990, states[0] = 20.974364, states[40]= 0.008776
Saving checkpoint... 
Iteration: 811980802, states[0] = -95.031580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825051105, states[0] = 11.228605, states[40]= 0.004938
Saving checkpoint... 
Iteration: 837924764, states[0] = -95.021232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851031406, states[0] = 18.256881, states[40]= 0.005822
Saving checkpoint... 
Iteration: 864140142, states[0] = -59.610562, states[40]= 0.000006
Saving checkpoint... 
Iteration: 877104808, states[0] = -23.794481, states[40]= 0.000767
Saving checkpoint... 
Iteration: 890186064, states[0] = -94.799427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903357298, states[0] = -94.998955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916532254, states[0] = 17.993382, states[40]= 0.005731
Saving checkpoint... 
Iteration: 929701857, states[0] = -94.834543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942840517, states[0] = -94.990821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956007910, states[0] = 23.993284, states[40]= 0.086243
Saving checkpoint... 
Iteration: 969149742, states[0] = -71.897735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982250123, states[0] = -94.914153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995347240, states[0] = -94.994192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008462094, states[0] = -95.028582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021605571, states[0] = -24.512163, states[40]= 0.000734
Saving checkpoint... 
Iteration: 1034751404, states[0] = -94.915767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047896179, states[0] = -95.013346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061037271, states[0] = 16.339172, states[40]= 0.005341
Saving checkpoint... 
Iteration: 1074186466, states[0] = -94.800423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087369122, states[0] = -95.003814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102083242, states[0] = -4.735540, states[40]= 0.003444
Saving checkpoint... 
Iteration: 1116832877, states[0] = -94.986557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131573420, states[0] = 1.306701, states[40]= 0.004401
Saving checkpoint... 
Iteration: 1146314071, states[0] = -94.974903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161069197, states[0] = 3.460692, states[40]= 0.004602
Saving checkpoint... 
Iteration: 1175820032, states[0] = -94.978806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190560291, states[0] = 7.500408, states[40]= 0.004824
Saving checkpoint... 
Iteration: 1205297891, states[0] = -94.962968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220013729, states[0] = 22.229960, states[40]= 0.023114
Saving checkpoint... 
Iteration: 1234716741, states[0] = -94.862697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249404349, states[0] = -95.015641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264082522, states[0] = -4.227655, states[40]= 0.003545
Saving checkpoint... 
Iteration: 1278250107, states[0] = -94.913935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292925796, states[0] = -95.021173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307558474, states[0] = 8.265364, states[40]= 0.004850
Saving checkpoint... 
Iteration: 1322189735, states[0] = -94.808459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336845531, states[0] = -94.993121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351514745, states[0] = 22.071883, states[40]= 0.019096
Saving checkpoint... 
Iteration: 1366196764, states[0] = -94.823799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379803903, states[0] = -94.967498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394280505, states[0] = -94.947709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408918072, states[0] = -95.019220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423528994, states[0] = 18.976302, states[40]= 0.006141
Saving checkpoint... 
Iteration: 1437009821, states[0] = 23.065265, states[40]= 0.054864
Saving checkpoint... 
Iteration: 1450104806, states[0] = -23.792263, states[40]= 0.000767
Saving checkpoint... 
Iteration: 1463223149, states[0] = -94.873704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476352680, states[0] = -94.996472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489480921, states[0] = -95.031148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502661165, states[0] = -95.220469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515722270, states[0] = -61.509876, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1528799573, states[0] = -95.279971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541878038, states[0] = -95.128318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554948695, states[0] = 8.431066, states[40]= 0.005622
Saving checkpoint... 
Iteration: 1568027080, states[0] = -95.230504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581595328, states[0] = -95.300742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594657459, states[0] = -95.081079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609007114, states[0] = -45.820998, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1623446050, states[0] = -94.667469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636381826, states[0] = -95.155850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649212651, states[0] = -52.575053, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1662036843, states[0] = 14.115781, states[40]= 0.006254
Saving checkpoint... 
Iteration: 1675471516, states[0] = -95.287784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688385725, states[0] = -95.299173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701203780, states[0] = -95.201545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714038630, states[0] = -91.323790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726873831, states[0] = -9.511206, states[40]= 0.002757
Saving checkpoint... 
Iteration: 1741338525, states[0] = -91.219367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755828973, states[0] = -95.241460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770362850, states[0] = -0.272089, states[40]= 0.004752
Saving checkpoint... 
Iteration: 1784847731, states[0] = -94.845415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797793886, states[0] = -95.182614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799999073, states[0] = -95.308420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812955430, states[0] = -95.072069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827493300, states[0] = -95.063178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842022487, states[0] = 20.450725, states[40]= 0.007862
Saving checkpoint... 
Iteration: 1856553230, states[0] = 10.155310, states[40]= 0.004915
Saving checkpoint... 
Iteration: 1870644479, states[0] = -65.579470, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1876007299, states[0] = 24.435872, states[40]= 0.099275
Saving checkpoint... 
Iteration: 1888885744, states[0] = -95.014393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901895626, states[0] = -95.015991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914904546, states[0] = -95.017544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927911484, states[0] = -95.018709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940939447, states[0] = -95.024783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953966721, states[0] = -95.029399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967992451, states[0] = -95.032797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982036226, states[0] = 16.691473, states[40]= 0.005405
Saving checkpoint... 
Iteration: 1996066088, states[0] = 4.930683, states[40]= 0.004703
Saving checkpoint... 
Iteration: 2010126102, states[0] = -44.392209, states[40]= 0.000068
Saving checkpoint... 
Iteration: 2024200460, states[0] = -94.831020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038277163, states[0] = -94.944057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052336735, states[0] = -94.988051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066376853, states[0] = -95.006100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080411804, states[0] = -95.017108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094462129, states[0] = -95.027820, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909015
 - CaMKt in component CaMK (millimolar): 0.007060
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.602696
 - nass in component intracellular_ions (millimolar): 6.602756
 - ki in component intracellular_ions (millimolar): 145.373503
 - kss in component intracellular_ions (millimolar): 145.373484
 - cansr in component intracellular_ions (millimolar): 1.317079
 - cajsr in component intracellular_ions (millimolar): 1.278980
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880125
 - hs in component INa (dimensionless): 0.880120
 - j in component INa (dimensionless): 0.880091
 - hsp in component INa (dimensionless): 0.726064
 - jp in component INa (dimensionless): 0.880072
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710029
 - hLp in component INaL (dimensionless): 0.451994
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620954
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695823
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935258
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001621
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329872
 - xs1 in component IKs (dimensionless): 0.241837
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:50:14 (2544): called boinc_finish(0)

</stderr_txt>
]]>


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