𝕏

Task 56002987

Name HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_634_0
Workunit 26596001
Created 3 Jul 2024, 23:26:04 UTC
Sent 4 Jul 2024, 0:55:06 UTC
Report deadline 7 Jul 2024, 10:31:06 UTC
Received 4 Jul 2024, 11:48:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241498
Run time 1 hours 36 min 32 sec
CPU time 1 hours 34 min 51 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.41 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_634.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_634_0_r1407684298_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012557406683_ORdGradInc_k_26-Pueyo_APDR-conf_634_0_r1407684298_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.479567
     * GNaL_b in INaL: 0.005582
     * Gto_b in Ito: 0.081837
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032133
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.165830
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.559543
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036799
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8720040, states[0] = -94.987804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22187635, states[0] = -94.879519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35371467, states[0] = -95.045100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48670873, states[0] = -94.743374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62541930, states[0] = 14.167086, states[40]= 0.005231
Saving checkpoint... 
Iteration: 75701370, states[0] = -94.855055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89339724, states[0] = -95.000542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102608373, states[0] = -29.231036, states[40]= 0.000491
Saving checkpoint... 
Iteration: 111184962, states[0] = -94.813308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124661490, states[0] = -92.755953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137826994, states[0] = -94.988087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148641929, states[0] = -64.724801, states[40]= 0.000002
Saving checkpoint... 
Iteration: 161847240, states[0] = -94.997603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174751166, states[0] = -94.922455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188439101, states[0] = -95.025726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201954043, states[0] = -95.028330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215335360, states[0] = -94.991009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228657028, states[0] = -88.108243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242286796, states[0] = -94.958307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250933032, states[0] = -95.024126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264072996, states[0] = 0.833520, states[40]= 0.004369
Saving checkpoint... 
Iteration: 277237979, states[0] = -94.904592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290889980, states[0] = -95.013040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304574404, states[0] = 0.043090, states[40]= 0.004270
Saving checkpoint... 
Iteration: 317916392, states[0] = -95.020286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331345717, states[0] = -94.995917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344889733, states[0] = -95.012914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358407611, states[0] = -95.018033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371862041, states[0] = -95.003038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385128123, states[0] = -48.833857, states[40]= 0.000033
Saving checkpoint... 
Iteration: 396473976, states[0] = -95.031053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405079541, states[0] = -3.132016, states[40]= 0.003767
Saving checkpoint... 
Iteration: 418846435, states[0] = -94.996196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432190120, states[0] = -94.820787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445805872, states[0] = -94.972801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459181010, states[0] = -94.797606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472843435, states[0] = -94.994733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485979311, states[0] = -95.031735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499422530, states[0] = -95.021616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512868140, states[0] = -95.005348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525400335, states[0] = -95.015944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538901869, states[0] = -95.016365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552295250, states[0] = -94.964899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565751890, states[0] = -94.922488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578725970, states[0] = -94.886583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592311946, states[0] = -94.976833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600655350, states[0] = -85.469842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609285933, states[0] = -94.957265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621761339, states[0] = -94.933361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634981574, states[0] = -95.031946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644143124, states[0] = -66.131402, states[40]= 0.000002
Saving checkpoint... 
Iteration: 657126923, states[0] = -47.542824, states[40]= 0.000040
Saving checkpoint... 
Iteration: 670574487, states[0] = -0.003970, states[40]= 0.004263
Saving checkpoint... 
Iteration: 684013416, states[0] = 22.513392, states[40]= 0.025059
Saving checkpoint... 
Iteration: 697617862, states[0] = -38.184957, states[40]= 0.000163
Saving checkpoint... 
Iteration: 710699021, states[0] = -94.838729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723776259, states[0] = -94.948505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737415043, states[0] = -95.019691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750488967, states[0] = -95.032818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763970440, states[0] = -95.030318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777333691, states[0] = -94.989603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790612194, states[0] = -32.620242, states[40]= 0.000341
Saving checkpoint... 
Iteration: 804069932, states[0] = 2.464821, states[40]= 0.004542
Saving checkpoint... 
Iteration: 817678936, states[0] = -94.788783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831035578, states[0] = 16.727714, states[40]= 0.005588
Saving checkpoint... 
Iteration: 844800509, states[0] = -94.968704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858577675, states[0] = -1.920007, states[40]= 0.003978
Saving checkpoint... 
Iteration: 872395865, states[0] = -95.014444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885812358, states[0] = -94.976924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899089524, states[0] = -10.981289, states[40]= 0.002146
Saving checkpoint... 
Iteration: 907703996, states[0] = -94.848223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920882067, states[0] = -95.010081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934296696, states[0] = -94.965781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948012271, states[0] = 22.746364, states[40]= 0.031675
Saving checkpoint... 
Iteration: 960909649, states[0] = -95.018194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973648818, states[0] = -74.270855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987121755, states[0] = -42.119032, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1000882519, states[0] = -95.010183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014172888, states[0] = -94.723815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027647492, states[0] = -72.220097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041184196, states[0] = -94.806780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054418866, states[0] = -95.020421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067736977, states[0] = -94.902671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081128854, states[0] = -49.624541, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1094741068, states[0] = -94.908303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108514808, states[0] = 22.253689, states[40]= 0.019357
Saving checkpoint... 
Iteration: 1121224299, states[0] = -94.883604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134510221, states[0] = 23.290524, states[40]= 0.049963
Saving checkpoint... 
Iteration: 1148169428, states[0] = -94.593385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161512784, states[0] = 22.638569, states[40]= 0.028456
Saving checkpoint... 
Iteration: 1174932437, states[0] = -95.023373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188180032, states[0] = -94.793446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201839670, states[0] = -94.992431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215086385, states[0] = -8.265042, states[40]= 0.002708
Saving checkpoint... 
Iteration: 1228714825, states[0] = -94.867738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241666282, states[0] = -94.272885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250041879, states[0] = 14.437926, states[40]= 0.005231
Saving checkpoint... 
Iteration: 1263550760, states[0] = 10.988302, states[40]= 0.005001
Saving checkpoint... 
Iteration: 1276707001, states[0] = -94.853638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289881519, states[0] = -95.009671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302806398, states[0] = -94.972643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315290586, states[0] = -94.960716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328827521, states[0] = -94.985885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342189959, states[0] = -94.819881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355817302, states[0] = -94.979799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369068539, states[0] = 3.170150, states[40]= 0.004605
Saving checkpoint... 
Iteration: 1382078962, states[0] = -2.747781, states[40]= 0.003837
Saving checkpoint... 
Iteration: 1395529509, states[0] = 18.726955, states[40]= 0.006259
Saving checkpoint... 
Iteration: 1409195048, states[0] = -94.830377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422599929, states[0] = -20.803377, states[40]= 0.000909
Saving checkpoint... 
Iteration: 1436039107, states[0] = 15.466660, states[40]= 0.005359
Saving checkpoint... 
Iteration: 1449800558, states[0] = -94.968369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463300317, states[0] = -94.968183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474181671, states[0] = -94.799219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487517511, states[0] = 21.749883, states[40]= 0.012896
Saving checkpoint... 
Iteration: 1500847955, states[0] = -95.196487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514266306, states[0] = -95.085048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527610925, states[0] = 23.902045, states[40]= 0.043498
Saving checkpoint... 
Iteration: 1540376473, states[0] = -95.131095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548635807, states[0] = 14.606948, states[40]= 0.006452
Saving checkpoint... 
Iteration: 1562009669, states[0] = -95.205892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574983404, states[0] = -95.291174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588484907, states[0] = -95.294563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601973010, states[0] = -95.287032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610758526, states[0] = 2.102271, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1624161740, states[0] = -95.278745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637399209, states[0] = -95.307323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650650715, states[0] = 6.733913, states[40]= 0.005545
Saving checkpoint... 
Iteration: 1663581859, states[0] = -19.270287, states[40]= 0.001111
Saving checkpoint... 
Iteration: 1676357985, states[0] = -95.276292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689784128, states[0] = -95.167963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703047397, states[0] = -95.265752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716733024, states[0] = -86.070663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729992738, states[0] = -95.185634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743418074, states[0] = -61.608773, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1756898348, states[0] = -37.613831, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1770341773, states[0] = 11.476729, states[40]= 0.006000
Saving checkpoint... 
Iteration: 1783681971, states[0] = -95.163383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796110520, states[0] = 23.854256, states[40]= 0.047259
Saving checkpoint... 
Iteration: 1808483743, states[0] = -95.080904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821807560, states[0] = -95.008191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835472732, states[0] = -95.053774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843872854, states[0] = -95.024871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857001010, states[0] = 47.889000, states[40]= 0.027814
Saving checkpoint... 
Iteration: 1870483138, states[0] = -95.039793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883787415, states[0] = -94.963451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892701107, states[0] = -94.846508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905697015, states[0] = -94.837020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919214594, states[0] = -94.868918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932517116, states[0] = 21.814221, states[40]= 0.013568
Saving checkpoint... 
Iteration: 1941158837, states[0] = -90.480839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954231733, states[0] = -94.895219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962117542, states[0] = -37.903281, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1976015485, states[0] = 22.126896, states[40]= 0.017272
Saving checkpoint... 
Iteration: 1989155177, states[0] = -85.209686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998008519, states[0] = 24.044776, states[40]= 0.074044
Saving checkpoint... 
Iteration: 2012218657, states[0] = -94.873892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025929664, states[0] = -95.022300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039333631, states[0] = -94.988805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048439861, states[0] = -95.024332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062564697, states[0] = 5.020771, states[40]= 0.004740
Saving checkpoint... 
Iteration: 2076860225, states[0] = -95.001217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090536732, states[0] = 16.322108, states[40]= 0.005504
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909114
 - CaMKt in component CaMK (millimolar): 0.006851
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573340
 - nass in component intracellular_ions (millimolar): 6.573400
 - ki in component intracellular_ions (millimolar): 145.405925
 - kss in component intracellular_ions (millimolar): 145.405906
 - cansr in component intracellular_ions (millimolar): 1.305281
 - cajsr in component intracellular_ions (millimolar): 1.267611
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880127
 - hs in component INa (dimensionless): 0.880122
 - j in component INa (dimensionless): 0.880095
 - hsp in component INa (dimensionless): 0.726069
 - jp in component INa (dimensionless): 0.880076
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710645
 - hLp in component INaL (dimensionless): 0.453829
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623399
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698681
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936426
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329088
 - xs1 in component IKs (dimensionless): 0.238433
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:48:07 (225835): called boinc_finish(0)

</stderr_txt>
]]>


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