𝕏

Task 56002542

Name HuVeMOp_20240704012543219507_ORdGradInc_k_26-Pueyo_APDR-conf_441_1
Workunit 26595778
Created 3 Jul 2024, 23:25:49 UTC
Sent 4 Jul 2024, 0:46:51 UTC
Report deadline 7 Jul 2024, 10:22:51 UTC
Received 4 Jul 2024, 10:43:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 41 min 25 sec
CPU time 1 hours 26 min 40 sec
Validate state Valid
Credit 62.51
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 4.10 GB
Peak disk usage 0.21 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012543219507_ORdGradInc_k_26-Pueyo_APDR-conf_441.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012543219507_ORdGradInc_k_26-Pueyo_APDR-conf_441_1_r2093611995_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012543219507_ORdGradInc_k_26-Pueyo_APDR-conf_441_1_r2093611995_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.154773
     * GNaL_b in INaL: 0.005469
     * Gto_b in Ito: 0.087418
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032135
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.160629
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.228244
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029335
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12321815, states[0] = -95.060079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26115828, states[0] = -38.923078, states[40]= 0.000147
Saving checkpoint... 
Iteration: 39533012, states[0] = 17.018269, states[40]= 0.005658
Saving checkpoint... 
Iteration: 52036260, states[0] = 16.053874, states[40]= 0.005409
Saving checkpoint... 
Iteration: 64390026, states[0] = -95.017939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77986208, states[0] = -95.033845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90112708, states[0] = -33.258662, states[40]= 0.000320
Saving checkpoint... 
Iteration: 103721368, states[0] = -94.863479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116954880, states[0] = -95.021640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130727600, states[0] = -94.871336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141765868, states[0] = -94.923445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155118401, states[0] = -38.456990, states[40]= 0.000160
Saving checkpoint... 
Iteration: 168306106, states[0] = -94.959753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179626473, states[0] = -46.684293, states[40]= 0.000047
Saving checkpoint... 
Iteration: 190900589, states[0] = -95.005727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204067139, states[0] = 3.941400, states[40]= 0.004642
Saving checkpoint... 
Iteration: 216429973, states[0] = -95.013297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228201659, states[0] = -94.820656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241102810, states[0] = -23.315555, states[40]= 0.000778
Saving checkpoint... 
Iteration: 253779630, states[0] = -94.936268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265212251, states[0] = -94.841628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278446728, states[0] = -95.016681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292432373, states[0] = -95.013633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304825253, states[0] = -94.972011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316809260, states[0] = -94.961248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329712565, states[0] = -94.842146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341385383, states[0] = -95.000302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352976541, states[0] = -95.021737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365005044, states[0] = 27.903002, states[40]= 0.149994
Saving checkpoint... 
Iteration: 378099006, states[0] = -19.667044, states[40]= 0.000988
Saving checkpoint... 
Iteration: 390777042, states[0] = -94.933549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403574139, states[0] = 0.314336, states[40]= 0.004290
Saving checkpoint... 
Iteration: 417155205, states[0] = -83.498368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429716872, states[0] = -94.850120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441205404, states[0] = -94.828035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453985953, states[0] = -95.023011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466831284, states[0] = -94.975526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480698920, states[0] = -94.814628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494229979, states[0] = -94.872713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506243504, states[0] = -94.893234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519069091, states[0] = 2.989832, states[40]= 0.004568
Saving checkpoint... 
Iteration: 533028239, states[0] = 18.878934, states[40]= 0.006288
Saving checkpoint... 
Iteration: 543887565, states[0] = -95.000918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556739562, states[0] = -94.887501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570243324, states[0] = -94.892936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582697079, states[0] = -94.810644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595682828, states[0] = -94.774865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606737030, states[0] = -94.883686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619280886, states[0] = -94.937188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632947894, states[0] = -95.016647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645389346, states[0] = -95.001456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658964220, states[0] = -95.019584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671239614, states[0] = -94.887502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683523344, states[0] = 20.150962, states[40]= 0.007595
Saving checkpoint... 
Iteration: 696712571, states[0] = -94.841908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710625792, states[0] = -45.930632, states[40]= 0.000053
Saving checkpoint... 
Iteration: 722954241, states[0] = -95.017790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735236612, states[0] = -94.882967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748066867, states[0] = 4.078256, states[40]= 0.004651
Saving checkpoint... 
Iteration: 759794876, states[0] = -94.949705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773211996, states[0] = -94.840760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786934520, states[0] = -95.013767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798434522, states[0] = -95.013760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811709284, states[0] = -94.835491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824570844, states[0] = 2.096384, states[40]= 0.004488
Saving checkpoint... 
Iteration: 836671453, states[0] = -94.596773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850653641, states[0] = -80.823463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864038663, states[0] = 15.519106, states[40]= 0.005274
Saving checkpoint... 
Iteration: 877330140, states[0] = -94.974582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890248776, states[0] = -94.900255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903413146, states[0] = -95.008467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915777114, states[0] = -94.933274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928262620, states[0] = -94.917567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941003078, states[0] = 36.450153, states[40]= 0.139927
Saving checkpoint... 
Iteration: 952878669, states[0] = -94.997475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965244716, states[0] = -94.894637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977595633, states[0] = -16.440188, states[40]= 0.001286
Saving checkpoint... 
Iteration: 989908435, states[0] = -95.007112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003003722, states[0] = 32.759137, states[40]= 0.154961
Saving checkpoint... 
Iteration: 1016552919, states[0] = 10.127189, states[40]= 0.004911
Saving checkpoint... 
Iteration: 1029271573, states[0] = -94.927471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041199799, states[0] = -94.816107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054171315, states[0] = -94.589476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067013103, states[0] = 22.045364, states[40]= 0.026550
Saving checkpoint... 
Iteration: 1080730690, states[0] = -94.873474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093632419, states[0] = -53.032811, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1106498868, states[0] = -95.024239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118908596, states[0] = -95.007073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132051734, states[0] = 10.599127, states[40]= 0.004926
Saving checkpoint... 
Iteration: 1145477010, states[0] = -95.021283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158610682, states[0] = -30.862404, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1172016278, states[0] = 21.538219, states[40]= 0.014978
Saving checkpoint... 
Iteration: 1185170093, states[0] = -94.511839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197467509, states[0] = -95.019773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211365122, states[0] = -94.991929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225298198, states[0] = -94.952140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237541295, states[0] = 14.573200, states[40]= 0.005158
Saving checkpoint... 
Iteration: 1249906298, states[0] = -95.006333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263006107, states[0] = 25.707305, states[40]= 0.127784
Saving checkpoint... 
Iteration: 1275718941, states[0] = -94.853317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289926835, states[0] = -95.011677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302202181, states[0] = -94.820891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314754535, states[0] = -94.907486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327734521, states[0] = -94.879366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341802921, states[0] = -94.955807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354766314, states[0] = -94.921510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367253292, states[0] = -94.905867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379355689, states[0] = -94.987646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392591521, states[0] = -12.578112, states[40]= 0.001848
Saving checkpoint... 
Iteration: 1405612288, states[0] = -32.412566, states[40]= 0.000355
Saving checkpoint... 
Iteration: 1418897824, states[0] = -95.003689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431393461, states[0] = -95.002297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444249347, states[0] = -94.900653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457745249, states[0] = -94.895055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470040063, states[0] = 15.019738, states[40]= 0.005208
Saving checkpoint... 
Iteration: 1483531185, states[0] = 18.006906, states[40]= 0.005866
Saving checkpoint... 
Iteration: 1496627486, states[0] = -47.719582, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1510614643, states[0] = -53.378157, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1524730437, states[0] = -76.714610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537920288, states[0] = -62.567498, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1549948980, states[0] = -94.900358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563122631, states[0] = -66.739143, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1576417706, states[0] = -95.217295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589492736, states[0] = -31.095601, states[40]= 0.000405
Saving checkpoint... 
Iteration: 1602556554, states[0] = -95.271287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614453257, states[0] = -95.047158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626665240, states[0] = -2.647074, states[40]= 0.004332
Saving checkpoint... 
Iteration: 1638899871, states[0] = -95.308992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650729818, states[0] = -79.197030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661578728, states[0] = -95.146493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674075992, states[0] = -12.801421, states[40]= 0.002049
Saving checkpoint... 
Iteration: 1687039894, states[0] = -93.152441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700505732, states[0] = -46.092027, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1714172898, states[0] = -95.289469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726855120, states[0] = 4.169521, states[40]= 0.005294
Saving checkpoint... 
Iteration: 1740225833, states[0] = -95.236318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753299635, states[0] = -39.026976, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1765205533, states[0] = 28.045234, states[40]= 0.125889
Saving checkpoint... 
Iteration: 1777053872, states[0] = -95.056865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789747760, states[0] = -95.264502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802069376, states[0] = 0.939652, states[40]= 0.004528
Saving checkpoint... 
Iteration: 1813949956, states[0] = -95.063250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825831579, states[0] = -95.008882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840258577, states[0] = -94.934881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853979401, states[0] = -95.036083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866815766, states[0] = -94.975044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877655607, states[0] = -85.063963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890082542, states[0] = -5.278631, states[40]= 0.003345
Saving checkpoint... 
Iteration: 1904154871, states[0] = -83.347331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915733489, states[0] = -94.879789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928902459, states[0] = -95.006349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941585702, states[0] = -7.564453, states[40]= 0.002856
Saving checkpoint... 
Iteration: 1955108468, states[0] = -28.776096, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1967834512, states[0] = -94.976865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979197363, states[0] = -94.810651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992423949, states[0] = -95.010717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005591628, states[0] = -12.685150, states[40]= 0.001829
Saving checkpoint... 
Iteration: 2019613222, states[0] = -33.323235, states[40]= 0.000318
Saving checkpoint... 
Iteration: 2032845281, states[0] = -94.982173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045696645, states[0] = -94.808737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058864488, states[0] = -94.991080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071645859, states[0] = -68.827197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2085556922, states[0] = 8.494414, states[40]= 0.004861
Saving checkpoint... 
Iteration: 2097663001, states[0] = -92.760580, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.899551
 - CaMKt in component CaMK (millimolar): 0.007015
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.582548
 - nass in component intracellular_ions (millimolar): 6.582608
 - ki in component intracellular_ions (millimolar): 145.394056
 - kss in component intracellular_ions (millimolar): 145.394037
 - cansr in component intracellular_ions (millimolar): 1.315450
 - cajsr in component intracellular_ions (millimolar): 1.277547
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879961
 - hs in component INa (dimensionless): 0.879956
 - j in component INa (dimensionless): 0.879926
 - hsp in component INa (dimensionless): 0.725754
 - jp in component INa (dimensionless): 0.879906
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710120
 - hLp in component INaL (dimensionless): 0.452721
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622683
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697903
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936837
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328804
 - xs1 in component IKs (dimensionless): 0.238712
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:43:03 (56267): called boinc_finish(0)

</stderr_txt>
]]>


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