𝕏

Task 56001724

Name HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_476_0
Workunit 26595375
Created 3 Jul 2024, 23:20:56 UTC
Sent 4 Jul 2024, 0:45:30 UTC
Report deadline 7 Jul 2024, 10:21:30 UTC
Received 6 Jul 2024, 16:56:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224565
Run time 1 hours 17 min 33 sec
CPU time 1 hours 14 min 23 sec
Validate state Valid
Credit 60.05
Device peak FLOPS 6.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_476_0_r1691401612_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_476_0_r1691401612_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.733543
     * GNaL_b in INaL: 0.005647
     * Gto_b in Ito: 0.087343
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032072
     * GKs_b in IKs: 0.001895
     * GK1_b in IK1: 0.166402
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.324268
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030646
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14834789, states[0] = -95.107632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29253096, states[0] = -95.005916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42451800, states[0] = -95.094889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56616146, states[0] = -36.371041, states[40]= 0.000216
Saving checkpoint... 
Iteration: 69307431, states[0] = -95.021437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83042241, states[0] = 14.271007, states[40]= 0.005089
Saving checkpoint... 
Iteration: 97137512, states[0] = -57.975396, states[40]= 0.000007
Saving checkpoint... 
Iteration: 110660173, states[0] = -90.525315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125347509, states[0] = -95.033777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139065215, states[0] = 5.131422, states[40]= 0.004700
Saving checkpoint... 
Iteration: 153149780, states[0] = -73.429301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166785791, states[0] = -94.990909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180698730, states[0] = -94.867068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194910069, states[0] = -95.054285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208666929, states[0] = -94.147765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222291458, states[0] = -94.995146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235436139, states[0] = -95.060241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249141903, states[0] = -62.621433, states[40]= 0.000003
Saving checkpoint... 
Iteration: 263169318, states[0] = -94.495985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276908913, states[0] = -95.053613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290835553, states[0] = -95.024940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303623238, states[0] = -42.110273, states[40]= 0.000095
Saving checkpoint... 
Iteration: 317176625, states[0] = -94.789771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331233147, states[0] = -94.928004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345786546, states[0] = -94.990687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360452432, states[0] = -95.063247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374462502, states[0] = -95.064979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388035155, states[0] = 16.884955, states[40]= 0.005443
Saving checkpoint... 
Iteration: 401938752, states[0] = -95.060574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416664147, states[0] = -93.257898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430877867, states[0] = -95.043711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445074882, states[0] = 0.314270, states[40]= 0.004274
Saving checkpoint... 
Iteration: 459631097, states[0] = -50.384377, states[40]= 0.000026
Saving checkpoint... 
Iteration: 474278989, states[0] = -94.983663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488408362, states[0] = -95.053293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501524779, states[0] = 19.917618, states[40]= 0.007003
Saving checkpoint... 
Iteration: 515388950, states[0] = -95.047472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529989248, states[0] = -95.068778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544787586, states[0] = -94.991463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559411065, states[0] = -95.053973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573071677, states[0] = 2.038151, states[40]= 0.004465
Saving checkpoint... 
Iteration: 587149194, states[0] = -72.394923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601773172, states[0] = -94.977864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615841863, states[0] = -95.028027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629386360, states[0] = -95.046539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643922292, states[0] = -95.056753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657834943, states[0] = -95.024343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671404826, states[0] = -95.052190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685722062, states[0] = -94.909952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699065972, states[0] = 4.823939, states[40]= 0.004681
Saving checkpoint... 
Iteration: 712654293, states[0] = -80.885819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726729629, states[0] = -94.922287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739882840, states[0] = -95.045267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753476084, states[0] = -95.066830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768143491, states[0] = -64.571816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 781387612, states[0] = -95.046854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796105203, states[0] = -24.629214, states[40]= 0.000721
Saving checkpoint... 
Iteration: 810736116, states[0] = -94.932127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823455532, states[0] = -95.063490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837065796, states[0] = 4.905320, states[40]= 0.004686
Saving checkpoint... 
Iteration: 851665028, states[0] = -93.616849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866251051, states[0] = -94.952566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880426358, states[0] = -95.057552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894495735, states[0] = -95.069343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908080116, states[0] = -2.848087, states[40]= 0.003795
Saving checkpoint... 
Iteration: 921599922, states[0] = -19.623233, states[40]= 0.000992
Saving checkpoint... 
Iteration: 935296734, states[0] = -94.998835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949400756, states[0] = -95.050835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963522433, states[0] = 20.463631, states[40]= 0.007899
Saving checkpoint... 
Iteration: 977605048, states[0] = -24.482204, states[40]= 0.000728
Saving checkpoint... 
Iteration: 991860239, states[0] = -95.036382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005779103, states[0] = -94.983416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019400644, states[0] = -95.050756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032564575, states[0] = 5.463315, states[40]= 0.004717
Saving checkpoint... 
Iteration: 1046650324, states[0] = -74.146676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059761934, states[0] = -94.965508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074402448, states[0] = -95.051244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088029187, states[0] = 18.739478, states[40]= 0.006069
Saving checkpoint... 
Iteration: 1102634142, states[0] = -53.714752, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1116770454, states[0] = -94.974731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130965350, states[0] = -95.064937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144526005, states[0] = 19.609068, states[40]= 0.006672
Saving checkpoint... 
Iteration: 1158229669, states[0] = -94.922060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172401513, states[0] = -95.050908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186725843, states[0] = -94.915905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201418063, states[0] = -95.055347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215165527, states[0] = -93.783876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228065386, states[0] = 5.094003, states[40]= 0.004696
Saving checkpoint... 
Iteration: 1241961626, states[0] = -95.064254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256030710, states[0] = 18.291549, states[40]= 0.005864
Saving checkpoint... 
Iteration: 1270544138, states[0] = 13.715920, states[40]= 0.005034
Saving checkpoint... 
Iteration: 1284522223, states[0] = 20.509581, states[40]= 0.008003
Saving checkpoint... 
Iteration: 1298575900, states[0] = -0.263355, states[40]= 0.004199
Saving checkpoint... 
Iteration: 1313067886, states[0] = 3.923326, states[40]= 0.004622
Saving checkpoint... 
Iteration: 1326900930, states[0] = -95.050635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341076930, states[0] = -0.865004, states[40]= 0.004115
Saving checkpoint... 
Iteration: 1355642084, states[0] = -62.833823, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1369273291, states[0] = -94.977471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383893229, states[0] = -95.048263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398543803, states[0] = 13.839714, states[40]= 0.005042
Saving checkpoint... 
Iteration: 1412822721, states[0] = -95.016750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426981978, states[0] = -95.067214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441001154, states[0] = 48.702796, states[40]= 0.038963
Saving checkpoint... 
Iteration: 1454528947, states[0] = 18.808365, states[40]= 0.006105
Saving checkpoint... 
Iteration: 1469119254, states[0] = -38.118555, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1482569011, states[0] = 3.379014, states[40]= 0.004582
Saving checkpoint... 
Iteration: 1496053911, states[0] = 9.968332, states[40]= 0.004879
Saving checkpoint... 
Iteration: 1510600257, states[0] = -35.743245, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1525199712, states[0] = -95.310729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539902371, states[0] = 42.223128, states[40]= 0.088131
Saving checkpoint... 
Iteration: 1554490541, states[0] = -95.198231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569141425, states[0] = -93.653700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583293512, states[0] = -95.212253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595940156, states[0] = -95.287190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610500737, states[0] = -39.202513, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1624905704, states[0] = -44.975428, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1638948543, states[0] = 8.118147, states[40]= 0.005593
Saving checkpoint... 
Iteration: 1652922322, states[0] = -95.266392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667691310, states[0] = -95.337019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681237748, states[0] = 13.517835, states[40]= 0.006149
Saving checkpoint... 
Iteration: 1695730985, states[0] = -80.567720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708849759, states[0] = 7.451459, states[40]= 0.005543
Saving checkpoint... 
Iteration: 1723317721, states[0] = -59.891687, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1737878046, states[0] = -95.327459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750958715, states[0] = -95.129609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765600547, states[0] = -39.108626, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1779803550, states[0] = -95.236316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793725072, states[0] = 18.875675, states[40]= 0.008042
Saving checkpoint... 
Iteration: 1808407328, states[0] = -95.102180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822947399, states[0] = -95.096048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836914038, states[0] = -95.077080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850990831, states[0] = -95.083338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864632011, states[0] = -52.154845, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1878226126, states[0] = -94.922821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892363537, states[0] = -95.041590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906397313, states[0] = -95.052064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919559515, states[0] = 7.631076, states[40]= 0.004811
Saving checkpoint... 
Iteration: 1933638485, states[0] = -58.702398, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1948242811, states[0] = -94.941743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962356510, states[0] = -95.034614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976568820, states[0] = 3.462975, states[40]= 0.004588
Saving checkpoint... 
Iteration: 1989832237, states[0] = -95.022149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002965219, states[0] = -95.064446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017286393, states[0] = -94.989483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030837903, states[0] = -95.025036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043898808, states[0] = -95.049521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057456733, states[0] = -95.062852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072031991, states[0] = 17.900404, states[40]= 0.005719
Saving checkpoint... 
Iteration: 2086551869, states[0] = 10.774790, states[40]= 0.004902
Saving checkpoint... 
Iteration: 2098782118, states[0] = -94.985462, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944870
 - CaMKt in component CaMK (millimolar): 0.007048
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.548240
 - nass in component intracellular_ions (millimolar): 6.548301
 - ki in component intracellular_ions (millimolar): 145.428097
 - kss in component intracellular_ions (millimolar): 145.428077
 - cansr in component intracellular_ions (millimolar): 1.316158
 - cajsr in component intracellular_ions (millimolar): 1.278098
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880745
 - hs in component INa (dimensionless): 0.880741
 - j in component INa (dimensionless): 0.880712
 - hsp in component INa (dimensionless): 0.727235
 - jp in component INa (dimensionless): 0.880693
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711178
 - hLp in component INaL (dimensionless): 0.453678
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621986
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697150
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936001
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327168
 - xs1 in component IKs (dimensionless): 0.240706
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:55:55 (30426): called boinc_finish(0)

</stderr_txt>
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