𝕏

Task 56001709

Name HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_674_1
Workunit 26595367
Created 3 Jul 2024, 23:20:56 UTC
Sent 4 Jul 2024, 0:39:25 UTC
Report deadline 7 Jul 2024, 10:15:25 UTC
Received 4 Jul 2024, 23:05:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241826
Run time 2 hours 43 min 16 sec
CPU time 2 hours 18 min 54 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 4.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_674.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_674_1_r83142055_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_674_1_r83142055_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.455627
     * GNaL_b in INaL: 0.006040
     * Gto_b in Ito: 0.087449
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031691
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.161241
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.417253
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031455
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15085784, states[0] = -9.028368, states[40]= 0.002531
Saving checkpoint... 
Iteration: 29822480, states[0] = -95.037631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44845886, states[0] = -95.031128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59552476, states[0] = 10.630230, states[40]= 0.004897
Saving checkpoint... 
Iteration: 74928708, states[0] = -95.041483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90535531, states[0] = 16.975643, states[40]= 0.005408
Saving checkpoint... 
Iteration: 105979738, states[0] = -95.043445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120156901, states[0] = -81.261449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135094315, states[0] = -13.032492, states[40]= 0.001756
Saving checkpoint... 
Iteration: 150671964, states[0] = -94.428427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166047038, states[0] = 13.011554, states[40]= 0.004965
Saving checkpoint... 
Iteration: 181198396, states[0] = -94.829888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195959011, states[0] = -95.035489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211157848, states[0] = -82.511761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226004405, states[0] = 29.750691, states[40]= 0.157674
Saving checkpoint... 
Iteration: 241541475, states[0] = 15.045297, states[40]= 0.005107
Saving checkpoint... 
Iteration: 256189886, states[0] = -94.810021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271503676, states[0] = 32.805632, states[40]= 0.155414
Saving checkpoint... 
Iteration: 286912661, states[0] = -95.024891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302252894, states[0] = -94.921756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316636605, states[0] = -54.030270, states[40]= 0.000015
Saving checkpoint... 
Iteration: 331532637, states[0] = 17.995294, states[40]= 0.005650
Saving checkpoint... 
Iteration: 346939511, states[0] = -95.031280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362433617, states[0] = -95.029987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377718067, states[0] = -94.867843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392000299, states[0] = -58.215216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407292862, states[0] = -94.964128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422092652, states[0] = -11.442968, states[40]= 0.002036
Saving checkpoint... 
Iteration: 437694896, states[0] = -94.821621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452474040, states[0] = -95.037446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467635375, states[0] = -52.691071, states[40]= 0.000018
Saving checkpoint... 
Iteration: 483239724, states[0] = -94.903385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498814020, states[0] = -94.980470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513813904, states[0] = -94.980379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528370287, states[0] = -95.010596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543978049, states[0] = -95.037987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559381922, states[0] = -95.015025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574920521, states[0] = -95.026734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590054493, states[0] = 10.182560, states[40]= 0.004872
Saving checkpoint... 
Iteration: 605182637, states[0] = -94.782411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619924735, states[0] = -95.027747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635512852, states[0] = 22.276348, states[40]= 0.027683
Saving checkpoint... 
Iteration: 650811987, states[0] = -94.978939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665731579, states[0] = -94.890723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681502008, states[0] = 44.361215, states[40]= 0.092288
Saving checkpoint... 
Iteration: 697008352, states[0] = 23.537706, states[40]= 0.078094
Saving checkpoint... 
Iteration: 711914537, states[0] = -95.025092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726478626, states[0] = -95.037951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742198415, states[0] = -94.829011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757516115, states[0] = 21.809442, states[40]= 0.015187
Saving checkpoint... 
Iteration: 772928454, states[0] = -95.028532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787852829, states[0] = -95.002754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802887319, states[0] = -95.016768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817570404, states[0] = 3.312176, states[40]= 0.004565
Saving checkpoint... 
Iteration: 832846410, states[0] = -94.999566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848621050, states[0] = -37.935787, states[40]= 0.000178
Saving checkpoint... 
Iteration: 863110653, states[0] = -28.085202, states[40]= 0.000570
Saving checkpoint... 
Iteration: 878603781, states[0] = -21.683683, states[40]= 0.000872
Saving checkpoint... 
Iteration: 894214079, states[0] = -94.860138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908969032, states[0] = -95.036359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923595914, states[0] = -14.378125, states[40]= 0.001545
Saving checkpoint... 
Iteration: 939116462, states[0] = -33.544006, states[40]= 0.000319
Saving checkpoint... 
Iteration: 954587600, states[0] = -7.222731, states[40]= 0.002904
Saving checkpoint... 
Iteration: 969927056, states[0] = -95.028072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984966066, states[0] = -95.035826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999679922, states[0] = -94.758999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014230493, states[0] = -94.888743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029662007, states[0] = -88.976412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044859733, states[0] = -95.005771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059559336, states[0] = 8.236339, states[40]= 0.004819
Saving checkpoint... 
Iteration: 1074895267, states[0] = -95.019222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090206227, states[0] = -94.844809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105123655, states[0] = -40.488071, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1120257479, states[0] = -94.926994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135317778, states[0] = -94.982617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150798581, states[0] = -94.968417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166427928, states[0] = -95.028149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182063563, states[0] = 6.449282, states[40]= 0.004754
Saving checkpoint... 
Iteration: 1196810764, states[0] = -94.977703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211712065, states[0] = -94.856116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227191138, states[0] = -94.812441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242865825, states[0] = -95.008282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257935970, states[0] = -95.029913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273211288, states[0] = -94.854589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288679334, states[0] = -94.751453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303414637, states[0] = -95.024727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318365298, states[0] = -95.008010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331742334, states[0] = -94.906629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347274913, states[0] = -94.946560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362497452, states[0] = -95.040058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377848891, states[0] = -95.000449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392253248, states[0] = -94.921474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406966937, states[0] = -95.035691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422353472, states[0] = -95.002640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437748328, states[0] = -94.914937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452919016, states[0] = -95.025772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468048174, states[0] = 12.601846, states[40]= 0.004946
Saving checkpoint... 
Iteration: 1483592653, states[0] = -11.443265, states[40]= 0.002036
Saving checkpoint... 
Iteration: 1498369302, states[0] = -95.009554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512955873, states[0] = 5.485614, states[40]= 0.005300
Saving checkpoint... 
Iteration: 1527277701, states[0] = -95.276226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542448541, states[0] = -94.649942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557543312, states[0] = -95.261454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571587330, states[0] = -95.172924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585900914, states[0] = -37.541128, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1586857486, states[0] = -95.082625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592846851, states[0] = -94.556809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600767558, states[0] = -95.296231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609303610, states[0] = -40.680835, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1618172491, states[0] = -95.301929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627029383, states[0] = -73.942517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1635770085, states[0] = -95.137894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644214833, states[0] = -95.232853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653125115, states[0] = -67.425300, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1662408936, states[0] = -46.928532, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1671641939, states[0] = 11.834536, states[40]= 0.005898
Saving checkpoint... 
Iteration: 1681614278, states[0] = -53.368954, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1690682897, states[0] = -95.170517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699570847, states[0] = -6.073025, states[40]= 0.003564
Saving checkpoint... 
Iteration: 1708455369, states[0] = -95.287083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717514138, states[0] = 22.354175, states[40]= 0.023020
Saving checkpoint... 
Iteration: 1726030790, states[0] = -76.460308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734921084, states[0] = 20.439107, states[40]= 0.009971
Saving checkpoint... 
Iteration: 1744229956, states[0] = 17.229066, states[40]= 0.006971
Saving checkpoint... 
Iteration: 1754258871, states[0] = -95.098305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763192836, states[0] = -29.041732, states[40]= 0.000509
Saving checkpoint... 
Iteration: 1772065866, states[0] = -95.297500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781270325, states[0] = -95.139373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790210925, states[0] = -49.319649, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1799058106, states[0] = -95.289915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808231379, states[0] = -94.939247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817095380, states[0] = -16.295166, states[40]= 0.001317
Saving checkpoint... 
Iteration: 1826194951, states[0] = -94.853749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835739717, states[0] = -94.928089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844184640, states[0] = -94.813979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852761659, states[0] = -94.947011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861418724, states[0] = -95.037169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870295223, states[0] = -94.974249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879186831, states[0] = -94.807543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888044601, states[0] = 13.840701, states[40]= 0.005017
Saving checkpoint... 
Iteration: 1898638458, states[0] = -56.359722, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1907843754, states[0] = -95.000413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916987081, states[0] = -95.040564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926598052, states[0] = -16.441415, states[40]= 0.001280
Saving checkpoint... 
Iteration: 1936504248, states[0] = 30.315813, states[40]= 0.158524
Saving checkpoint... 
Iteration: 1946082764, states[0] = -3.734552, states[40]= 0.003621
Saving checkpoint... 
Iteration: 1955194585, states[0] = -94.820608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964091237, states[0] = -10.239461, states[40]= 0.002271
Saving checkpoint... 
Iteration: 1973654846, states[0] = -77.418181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983022248, states[0] = 20.726966, states[40]= 0.008003
Saving checkpoint... 
Iteration: 1992642454, states[0] = -60.587748, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2001817878, states[0] = -94.982238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011260993, states[0] = -94.930749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020339308, states[0] = -94.995099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029773075, states[0] = -94.944214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039301192, states[0] = -94.969924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049346260, states[0] = -94.998672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059199632, states[0] = -94.830669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068938868, states[0] = -95.029968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078252611, states[0] = -94.920155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087615839, states[0] = -32.954811, states[40]= 0.000343
Saving checkpoint... 
Iteration: 2097199531, states[0] = -94.830409, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.915706
 - CaMKt in component CaMK (millimolar): 0.007068
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.544632
 - nass in component intracellular_ions (millimolar): 6.544692
 - ki in component intracellular_ions (millimolar): 145.431847
 - kss in component intracellular_ions (millimolar): 145.431828
 - cansr in component intracellular_ions (millimolar): 1.315905
 - cajsr in component intracellular_ions (millimolar): 1.277638
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880241
 - hs in component INa (dimensionless): 0.880236
 - j in component INa (dimensionless): 0.880206
 - hsp in component INa (dimensionless): 0.726282
 - jp in component INa (dimensionless): 0.880187
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709778
 - hLp in component INaL (dimensionless): 0.450912
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619361
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693915
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934342
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331565
 - xs1 in component IKs (dimensionless): 0.244324
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:41:32 (11841): called boinc_finish(0)

</stderr_txt>
]]>


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