𝕏

Task 56001514

Name HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733_0
Workunit 26595270
Created 3 Jul 2024, 23:20:46 UTC
Sent 4 Jul 2024, 0:39:25 UTC
Report deadline 7 Jul 2024, 10:15:25 UTC
Received 4 Jul 2024, 12:20:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241826
Run time 2 hours 27 min 19 sec
CPU time 2 hours 20 min 5 sec
Validate state Valid
Credit 69.62
Device peak FLOPS 4.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.59 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733_0_r410986587_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733_0_r410986587_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.088280
     * GNaL_b in INaL: 0.005494
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032216
     * GKs_b in IKs: 0.001910
     * GK1_b in IK1: 0.161662
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.837272
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16314301, states[0] = -95.062310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33423440, states[0] = -95.072841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50583115, states[0] = -6.262982, states[40]= 0.003138
Saving checkpoint... 
Iteration: 67827422, states[0] = -95.008918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84498560, states[0] = -95.053204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100929674, states[0] = -95.038445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117967415, states[0] = -95.043465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135520994, states[0] = 20.740514, states[40]= 0.008803
Saving checkpoint... 
Iteration: 152411496, states[0] = -95.029783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168963192, states[0] = -95.040227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186042918, states[0] = 14.053266, states[40]= 0.005087
Saving checkpoint... 
Iteration: 202795868, states[0] = -94.972840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219212612, states[0] = -94.866941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235313022, states[0] = -94.985393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252728117, states[0] = -94.893661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270078942, states[0] = -2.417598, states[40]= 0.003869
Saving checkpoint... 
Iteration: 287062957, states[0] = 5.996660, states[40]= 0.004746
Saving checkpoint... 
Iteration: 302845887, states[0] = -95.004390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319069258, states[0] = 3.031211, states[40]= 0.004554
Saving checkpoint... 
Iteration: 336192333, states[0] = -94.825930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353260120, states[0] = -94.937607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369753362, states[0] = -94.929444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385803285, states[0] = -94.978225, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733_0_r410986587_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_733_0_r410986587_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.088280
     * GNaL_b in INaL: 0.005494
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032216
     * GKs_b in IKs: 0.001910
     * GK1_b in IK1: 0.161662
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.837272
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 385803285
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.978225 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 396757623, states[0] = -94.934630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410273529, states[0] = -94.952155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422913127, states[0] = -95.028847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437009168, states[0] = 23.098066, states[40]= 0.063998
Saving checkpoint... 
Iteration: 450255082, states[0] = -94.931518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463652249, states[0] = -78.355872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476311277, states[0] = -94.983931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489972113, states[0] = -95.040690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504007939, states[0] = 23.758900, states[40]= 0.085389
Saving checkpoint... 
Iteration: 518468853, states[0] = -95.040171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532311174, states[0] = -94.983823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544861342, states[0] = -95.011314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559591293, states[0] = -12.106955, states[40]= 0.001923
Saving checkpoint... 
Iteration: 573975798, states[0] = -95.041183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588488355, states[0] = -95.042901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601983747, states[0] = -95.042282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616456089, states[0] = -95.037995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630293828, states[0] = -94.970619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644662875, states[0] = -92.731444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658471031, states[0] = -95.040416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671765989, states[0] = -94.944029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686117653, states[0] = -37.381656, states[40]= 0.000185
Saving checkpoint... 
Iteration: 700601294, states[0] = -21.581886, states[40]= 0.000862
Saving checkpoint... 
Iteration: 715150701, states[0] = -75.800460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728463456, states[0] = -95.039173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742986140, states[0] = -95.042511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757561069, states[0] = 6.829717, states[40]= 0.004784
Saving checkpoint... 
Iteration: 772056746, states[0] = 8.662770, states[40]= 0.004849
Saving checkpoint... 
Iteration: 785951576, states[0] = -95.037076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800337313, states[0] = -94.999636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814393409, states[0] = -95.022923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828300772, states[0] = -94.976026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842588676, states[0] = -9.774651, states[40]= 0.002376
Saving checkpoint... 
Iteration: 856396263, states[0] = -95.023783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870762710, states[0] = -94.940243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885381724, states[0] = -95.018989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900009742, states[0] = 22.881034, states[40]= 0.055860
Saving checkpoint... 
Iteration: 912596504, states[0] = -16.994931, states[40]= 0.001219
Saving checkpoint... 
Iteration: 927081332, states[0] = -4.016312, states[40]= 0.003578
Saving checkpoint... 
Iteration: 941514491, states[0] = 21.902145, states[40]= 0.020064
Saving checkpoint... 
Iteration: 955915821, states[0] = -95.029197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970180630, states[0] = -94.791789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984501839, states[0] = 45.532650, states[40]= 0.081926
Saving checkpoint... 
Iteration: 998394193, states[0] = -95.023050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012645183, states[0] = -67.756024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027107995, states[0] = -28.004614, states[40]= 0.000553
Saving checkpoint... 
Iteration: 1040702368, states[0] = -94.846428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055254410, states[0] = -94.930296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069899675, states[0] = -95.024673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084310278, states[0] = -94.982839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097787812, states[0] = -94.965194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112073536, states[0] = 0.794929, states[40]= 0.004331
Saving checkpoint... 
Iteration: 1126678001, states[0] = -94.774875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141146398, states[0] = -69.394572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155529652, states[0] = 18.554862, states[40]= 0.006052
Saving checkpoint... 
Iteration: 1169390956, states[0] = -95.021912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183299704, states[0] = -94.974968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197597702, states[0] = -18.139962, states[40]= 0.001106
Saving checkpoint... 
Iteration: 1212262078, states[0] = -94.939301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226297480, states[0] = -94.973191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240952897, states[0] = -95.037022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255455904, states[0] = -95.037549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269885631, states[0] = -95.020088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283599370, states[0] = -19.737761, states[40]= 0.000978
Saving checkpoint... 
Iteration: 1297797549, states[0] = -94.973199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312123269, states[0] = -43.042687, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1326750326, states[0] = -94.924968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341097138, states[0] = -17.600337, states[40]= 0.001157
Saving checkpoint... 
Iteration: 1354955361, states[0] = -95.037388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369000738, states[0] = 43.053644, states[40]= 0.009168
Saving checkpoint... 
Iteration: 1383266451, states[0] = -94.944071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397627396, states[0] = -47.367212, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1411523878, states[0] = 20.111034, states[40]= 0.007373
Saving checkpoint... 
Iteration: 1425709914, states[0] = -94.860917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440224481, states[0] = -94.886865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454631344, states[0] = -51.619002, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1468464334, states[0] = -95.038836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482787006, states[0] = -94.964234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497187758, states[0] = -94.814665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511586548, states[0] = -95.138453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526100741, states[0] = 42.984565, states[40]= 0.006962
Saving checkpoint... 
Iteration: 1539950608, states[0] = 7.236173, states[40]= 0.005508
Saving checkpoint... 
Iteration: 1553963858, states[0] = -95.285483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568380569, states[0] = -95.304837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582843985, states[0] = 10.442892, states[40]= 0.005796
Saving checkpoint... 
Iteration: 1596830642, states[0] = -95.258564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610763434, states[0] = -1.131433, states[40]= 0.004594
Saving checkpoint... 
Iteration: 1625133451, states[0] = 15.430071, states[40]= 0.006549
Saving checkpoint... 
Iteration: 1639227704, states[0] = 17.848172, states[40]= 0.007416
Saving checkpoint... 
Iteration: 1653252632, states[0] = -95.287617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666752399, states[0] = -95.287559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680927746, states[0] = 17.824232, states[40]= 0.007406
Saving checkpoint... 
Iteration: 1695460330, states[0] = -95.117832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710020981, states[0] = 20.260579, states[40]= 0.010101
Saving checkpoint... 
Iteration: 1723917910, states[0] = -60.984034, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1737053338, states[0] = 5.297570, states[40]= 0.005375
Saving checkpoint... 
Iteration: 1751288601, states[0] = -95.190043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765859709, states[0] = 1.389612, states[40]= 0.004971
Saving checkpoint... 
Iteration: 1780029079, states[0] = -77.871150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793259274, states[0] = -95.113855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807980169, states[0] = -95.094212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822119927, states[0] = -42.109308, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1835869189, states[0] = -95.038863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849662753, states[0] = -93.301495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864325237, states[0] = -95.002973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878979140, states[0] = -95.047840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893270707, states[0] = -94.952950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907563134, states[0] = 5.852283, states[40]= 0.004741
Saving checkpoint... 
Iteration: 1921388338, states[0] = -95.022558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935958436, states[0] = -95.038824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949895313, states[0] = -95.023612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964115810, states[0] = -35.604584, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1978163429, states[0] = -93.040924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990418656, states[0] = -95.029456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003788695, states[0] = -94.965504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015758813, states[0] = -94.935061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030118504, states[0] = -38.229394, states[40]= 0.000164
Saving checkpoint... 
Iteration: 2044629429, states[0] = -49.548052, states[40]= 0.000029
Saving checkpoint... 
Iteration: 2058797958, states[0] = -94.973008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072486883, states[0] = -95.041714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086038940, states[0] = 15.504354, states[40]= 0.005245
Saving checkpoint... 
Iteration: 2099597827, states[0] = -18.259666, states[40]= 0.001096
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.919178
 - CaMKt in component CaMK (millimolar): 0.006962
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.578941
 - nass in component intracellular_ions (millimolar): 6.579001
 - ki in component intracellular_ions (millimolar): 145.398734
 - kss in component intracellular_ions (millimolar): 145.398715
 - cansr in component intracellular_ions (millimolar): 1.310817
 - cajsr in component intracellular_ions (millimolar): 1.272938
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880301
 - hs in component INa (dimensionless): 0.880296
 - j in component INa (dimensionless): 0.880268
 - hsp in component INa (dimensionless): 0.726396
 - jp in component INa (dimensionless): 0.880248
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710635
 - hLp in component INaL (dimensionless): 0.453293
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622616
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697833
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936506
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001595
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326631
 - xs1 in component IKs (dimensionless): 0.239385
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:49:50 (2578): called boinc_finish(0)

</stderr_txt>
]]>


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