𝕏

Task 56001512

Name HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33_0
Workunit 26595269
Created 3 Jul 2024, 23:20:46 UTC
Sent 4 Jul 2024, 0:39:25 UTC
Report deadline 7 Jul 2024, 10:15:25 UTC
Received 4 Jul 2024, 11:08:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241826
Run time 2 hours 20 min 53 sec
CPU time 2 hours 14 min 28 sec
Validate state Valid
Credit 63.95
Device peak FLOPS 4.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.51 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33_0_r172464213_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33_0_r172464213_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.620949
     * GNaL_b in INaL: 0.005506
     * Gto_b in Ito: 0.086338
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032323
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.161312
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.518157
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031367
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16307669, states[0] = -95.024610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32796687, states[0] = -94.979454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49283684, states[0] = -94.949355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66451012, states[0] = -95.014502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83612707, states[0] = -33.557700, states[40]= 0.000308
Saving checkpoint... 
Iteration: 99979236, states[0] = -95.009128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116999704, states[0] = -95.009490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133794934, states[0] = -94.934300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150234158, states[0] = -94.863682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166321432, states[0] = -94.952262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183300366, states[0] = -94.937016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200036432, states[0] = 16.281866, states[40]= 0.005402
Saving checkpoint... 
Iteration: 217017558, states[0] = 21.367601, states[40]= 0.012453
Saving checkpoint... 
Iteration: 233431157, states[0] = -94.994706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249107720, states[0] = -28.203635, states[40]= 0.000545
Saving checkpoint... 
Iteration: 265267457, states[0] = -94.905851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281851178, states[0] = -94.967844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298774606, states[0] = -94.913364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315158278, states[0] = -88.597077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332062130, states[0] = 6.193996, states[40]= 0.004774
Saving checkpoint... 
Iteration: 349166354, states[0] = -94.039075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365489779, states[0] = -95.004641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381862184, states[0] = -94.972734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398941288, states[0] = -94.996659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416135728, states[0] = -56.895117, states[40]= 0.000009
Saving checkpoint... 
Iteration: 433175742, states[0] = -94.709763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449825991, states[0] = -94.954106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466547287, states[0] = 12.295109, states[40]= 0.004996
Saving checkpoint... 
Iteration: 483311845, states[0] = -94.944842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500483017, states[0] = -95.003646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516912399, states[0] = -94.989805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533391221, states[0] = -94.983528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550517909, states[0] = 21.307105, states[40]= 0.011918
Saving checkpoint... 
Iteration: 567556887, states[0] = 8.454201, states[40]= 0.004861
Saving checkpoint... 
Iteration: 583917810, states[0] = -94.991173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600187508, states[0] = -94.772733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617529332, states[0] = 18.573633, states[40]= 0.006107
Saving checkpoint... 
Iteration: 634512283, states[0] = 22.246568, states[40]= 0.031342
Saving checkpoint... 
Iteration: 651560929, states[0] = 6.725194, states[40]= 0.004798
Saving checkpoint... 
Iteration: 667813024, states[0] = -94.945541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684581411, states[0] = -4.388526, states[40]= 0.003521
Saving checkpoint... 
Iteration: 701660000, states[0] = -90.616188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718928743, states[0] = -94.993728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735553713, states[0] = 9.759750, states[40]= 0.004902
Saving checkpoint... 
Iteration: 752416440, states[0] = -94.990711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769446090, states[0] = -94.997373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786266780, states[0] = -94.904718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803052675, states[0] = 10.178349, states[40]= 0.004915
Saving checkpoint... 
Iteration: 819624570, states[0] = -44.852610, states[40]= 0.000062
Saving checkpoint... 
Iteration: 836810598, states[0] = -94.943730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853801220, states[0] = -94.936750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870757380, states[0] = -94.893760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886909059, states[0] = -94.988653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903465322, states[0] = -95.000723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920502313, states[0] = 41.906336, states[40]= 0.108665
Saving checkpoint... 
Iteration: 937865951, states[0] = -94.973954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954272652, states[0] = -94.910901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970610120, states[0] = -30.507032, states[40]= 0.000437


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33_0_r172464213_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704012042104244_ORdGradInc_k_26-Pueyo_APDR-conf_33_0_r172464213_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.620949
     * GNaL_b in INaL: 0.005506
     * Gto_b in Ito: 0.086338
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032323
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.161312
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.518157
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031367
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 970610120
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -30.507032 (After loading)
 - states[40]: 0.000437 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 981797527, states[0] = -94.933737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995352442, states[0] = -94.967946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007928889, states[0] = -94.993571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021549143, states[0] = 11.575945, states[40]= 0.004964
Saving checkpoint... 
Iteration: 1034768121, states[0] = -94.906024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048116713, states[0] = -36.910866, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1061292249, states[0] = -94.929305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075266505, states[0] = -94.904222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089161888, states[0] = -92.210500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103640118, states[0] = -61.906918, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1117193767, states[0] = -94.786744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129667667, states[0] = -94.267039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144283123, states[0] = -94.921104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158634936, states[0] = -56.013584, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1172753166, states[0] = -94.888320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186119684, states[0] = -39.859144, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1200344861, states[0] = -94.964105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214137241, states[0] = -58.593459, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1228250937, states[0] = -94.885419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242014720, states[0] = 21.837602, states[40]= 0.019278
Saving checkpoint... 
Iteration: 1255493197, states[0] = -95.004487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270130217, states[0] = -50.852579, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1284703936, states[0] = -94.807879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299235056, states[0] = -94.862973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311655029, states[0] = -83.572127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326309821, states[0] = -94.942854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341034111, states[0] = 17.071068, states[40]= 0.005573
Saving checkpoint... 
Iteration: 1355769695, states[0] = -94.907513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369277428, states[0] = -94.915475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383771204, states[0] = -94.909100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397649199, states[0] = -73.908551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411561097, states[0] = 6.651628, states[40]= 0.004795
Saving checkpoint... 
Iteration: 1425561380, states[0] = 6.527012, states[40]= 0.004789
Saving checkpoint... 
Iteration: 1439495949, states[0] = -95.004706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454037939, states[0] = 15.760305, states[40]= 0.005312
Saving checkpoint... 
Iteration: 1468398325, states[0] = -94.985154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482975346, states[0] = -95.001902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495376557, states[0] = -94.977765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509849395, states[0] = -95.196748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524284516, states[0] = -95.245022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538720956, states[0] = 20.435011, states[40]= 0.010219
Saving checkpoint... 
Iteration: 1552777931, states[0] = -95.260282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566698510, states[0] = -37.394798, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1580453133, states[0] = 5.393867, states[40]= 0.005396
Saving checkpoint... 
Iteration: 1594695644, states[0] = -95.162497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609196645, states[0] = -95.285904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622672806, states[0] = -95.268680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636984997, states[0] = -95.142644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651519131, states[0] = 20.803993, states[40]= 0.011810
Saving checkpoint... 
Iteration: 1665970197, states[0] = -7.032446, states[40]= 0.003349
Saving checkpoint... 
Iteration: 1679077877, states[0] = -95.274066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693341140, states[0] = -93.786517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707644345, states[0] = 10.072483, states[40]= 0.005793
Saving checkpoint... 
Iteration: 1722009710, states[0] = 23.685150, states[40]= 0.056534
Saving checkpoint... 
Iteration: 1736202687, states[0] = -42.653659, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1750026297, states[0] = -73.373075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1763995232, states[0] = -95.287044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778095632, states[0] = -95.287306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792464488, states[0] = -95.262522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806248404, states[0] = -94.933513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820490734, states[0] = -95.042791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834925782, states[0] = -95.018017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849159395, states[0] = -91.209715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863025439, states[0] = 19.542892, states[40]= 0.006867
Saving checkpoint... 
Iteration: 1876887996, states[0] = -94.988897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891437168, states[0] = -94.999538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905924976, states[0] = -94.995114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920462721, states[0] = -95.001584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934095076, states[0] = -16.160231, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1947908726, states[0] = -94.988700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962223177, states[0] = -94.843853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976560693, states[0] = 6.821152, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1990455280, states[0] = -94.998486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004502860, states[0] = 37.745272, states[40]= 0.133467
Saving checkpoint... 
Iteration: 2018940981, states[0] = -94.995580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033150983, states[0] = -76.731295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046772853, states[0] = -94.910379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060779863, states[0] = -94.917374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075102532, states[0] = -23.227799, states[40]= 0.000780
Saving checkpoint... 
Iteration: 2089371642, states[0] = -94.975445, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.880583
 - CaMKt in component CaMK (millimolar): 0.006998
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.557381
 - nass in component intracellular_ions (millimolar): 6.557441
 - ki in component intracellular_ions (millimolar): 145.419395
 - kss in component intracellular_ions (millimolar): 145.419375
 - cansr in component intracellular_ions (millimolar): 1.314606
 - cajsr in component intracellular_ions (millimolar): 1.276737
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003626
 - hf in component INa (dimensionless): 0.879631
 - hs in component INa (dimensionless): 0.879627
 - j in component INa (dimensionless): 0.879597
 - hsp in component INa (dimensionless): 0.725134
 - jp in component INa (dimensionless): 0.879578
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709692
 - hLp in component INaL (dimensionless): 0.452373
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622801
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.698037
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936936
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327461
 - xs1 in component IKs (dimensionless): 0.238314
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997343
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:07:50 (2573): called boinc_finish(0)

</stderr_txt>
]]>


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