𝕏

Task 56001323

Name HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281_0
Workunit 26595186
Created 3 Jul 2024, 23:16:38 UTC
Sent 4 Jul 2024, 0:39:25 UTC
Report deadline 7 Jul 2024, 10:15:25 UTC
Received 4 Jul 2024, 12:20:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241826
Run time 2 hours 23 min 21 sec
CPU time 2 hours 16 min 12 sec
Validate state Valid
Credit 61.79
Device peak FLOPS 4.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.55 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r933377774_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r933377774_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.778766
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.087385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.167507
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.112738
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029368
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16447269, states[0] = -95.098909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33368344, states[0] = -95.044503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50395395, states[0] = -95.037219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67182395, states[0] = -94.805489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82827277, states[0] = -94.993257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98433207, states[0] = -95.029320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114980233, states[0] = -95.035469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131636242, states[0] = -54.999752, states[40]= 0.000012
Saving checkpoint... 
Iteration: 148058799, states[0] = 8.076693, states[40]= 0.004831
Saving checkpoint... 
Iteration: 165067547, states[0] = 4.230243, states[40]= 0.004649
Saving checkpoint... 
Iteration: 182295804, states[0] = -94.963190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199139337, states[0] = -58.312565, states[40]= 0.000007
Saving checkpoint... 
Iteration: 215471008, states[0] = -95.030920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232238570, states[0] = -94.900155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249382241, states[0] = -95.009727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266369775, states[0] = -95.005077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283331600, states[0] = -94.986977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299814104, states[0] = -94.976157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316553911, states[0] = 10.082048, states[40]= 0.004886
Saving checkpoint... 
Iteration: 333557117, states[0] = 8.794448, states[40]= 0.004851
Saving checkpoint... 
Iteration: 350441747, states[0] = -95.025529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366246437, states[0] = -94.910886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382920079, states[0] = -95.020695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399855907, states[0] = -94.999134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416345750, states[0] = -94.994347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432982677, states[0] = -95.032290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449660393, states[0] = -88.938933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466982757, states[0] = -95.032278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484014544, states[0] = 21.894625, states[40]= 0.019762
Saving checkpoint... 
Iteration: 500722580, states[0] = -94.874863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516424357, states[0] = -95.021631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532496442, states[0] = -95.033986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549301130, states[0] = -94.966670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566262541, states[0] = -94.930562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582011364, states[0] = 22.419202, states[40]= 0.038372
Saving checkpoint... 
Iteration: 599133660, states[0] = -52.024494, states[40]= 0.000020
Saving checkpoint... 
Iteration: 616363075, states[0] = -95.002088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632474492, states[0] = -95.030992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648645136, states[0] = -65.172727, states[40]= 0.000002
Saving checkpoint... 
Iteration: 665577046, states[0] = -0.701759, states[40]= 0.004142
Saving checkpoint... 
Iteration: 682312758, states[0] = -94.974974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699391039, states[0] = -95.012307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715794229, states[0] = -94.961094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731750775, states[0] = -94.916298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748557139, states[0] = 8.785670, states[40]= 0.004851
Saving checkpoint... 
Iteration: 765740826, states[0] = -94.902910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782680684, states[0] = -94.780651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798499966, states[0] = -95.034222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815105994, states[0] = -24.728304, states[40]= 0.000727


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r933377774_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r933377774_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.778766
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.087385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.167507
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.112738
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029368
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 815105994
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -24.728304 (After loading)
 - states[40]: 0.000727 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 826559330, states[0] = 7.880932, states[40]= 0.004824
Saving checkpoint... 
Iteration: 840061124, states[0] = 7.122879, states[40]= 0.004797
Saving checkpoint... 
Iteration: 852650672, states[0] = -72.819095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866301563, states[0] = -94.966786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879887189, states[0] = -95.010926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893364254, states[0] = -95.002391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906350786, states[0] = -94.996441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920085784, states[0] = -6.564235, states[40]= 0.003059
Saving checkpoint... 
Iteration: 934048785, states[0] = 12.068521, states[40]= 0.004947
Saving checkpoint... 
Iteration: 948393846, states[0] = -95.013029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962037060, states[0] = 16.316413, states[40]= 0.005318
Saving checkpoint... 
Iteration: 974502640, states[0] = 39.251070, states[40]= 0.126828
Saving checkpoint... 
Iteration: 988925723, states[0] = -95.021632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003461650, states[0] = -95.028727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018110048, states[0] = -28.523642, states[40]= 0.000547
Saving checkpoint... 
Iteration: 1031644919, states[0] = -64.899317, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1046337835, states[0] = -94.989862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060211871, states[0] = -94.855532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074439754, states[0] = -95.024634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088149958, states[0] = -71.743330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101492614, states[0] = -95.033135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116001594, states[0] = 47.482911, states[40]= 0.068832
Saving checkpoint... 
Iteration: 1130541502, states[0] = 14.763354, states[40]= 0.005116
Saving checkpoint... 
Iteration: 1145031757, states[0] = 18.032974, states[40]= 0.005741
Saving checkpoint... 
Iteration: 1157888282, states[0] = -95.011101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172592060, states[0] = -11.797852, states[40]= 0.001980
Saving checkpoint... 
Iteration: 1187266359, states[0] = -94.934378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201742927, states[0] = -94.905549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215153253, states[0] = -76.969455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229622491, states[0] = -40.426864, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1243517475, states[0] = 21.447167, states[40]= 0.012458
Saving checkpoint... 
Iteration: 1257856990, states[0] = -94.999036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271905461, states[0] = -95.016255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285762326, states[0] = -94.929830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300273722, states[0] = -94.942020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314650864, states[0] = -73.112744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328971352, states[0] = -95.030052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341411405, states[0] = -95.017832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356002727, states[0] = 38.602523, states[40]= 0.130649
Saving checkpoint... 
Iteration: 1370488960, states[0] = -95.032491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384826647, states[0] = -94.983337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398596492, states[0] = -15.844849, states[40]= 0.001355
Saving checkpoint... 
Iteration: 1412604668, states[0] = -23.488631, states[40]= 0.000784
Saving checkpoint... 
Iteration: 1426244173, states[0] = -94.907109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440795233, states[0] = -94.961422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455266275, states[0] = -94.934105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468692419, states[0] = -94.816394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483140595, states[0] = -59.724312, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1497786272, states[0] = -94.953775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512074008, states[0] = -7.541570, states[40]= 0.003171
Saving checkpoint... 
Iteration: 1524741519, states[0] = -92.043452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538960450, states[0] = -95.253680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553216034, states[0] = -55.618540, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1567461675, states[0] = -95.267242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581502039, states[0] = -95.190342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595127072, states[0] = 18.229850, states[40]= 0.007512
Saving checkpoint... 
Iteration: 1608651016, states[0] = 6.944789, states[40]= 0.005507
Saving checkpoint... 
Iteration: 1622817418, states[0] = -58.199044, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1637122237, states[0] = 19.928134, states[40]= 0.009229
Saving checkpoint... 
Iteration: 1650620457, states[0] = 20.493707, states[40]= 0.010421
Saving checkpoint... 
Iteration: 1664636780, states[0] = -95.248016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679196213, states[0] = -33.513664, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1693375292, states[0] = -95.138762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705957065, states[0] = -95.081545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719341352, states[0] = 11.885764, states[40]= 0.005934
Saving checkpoint... 
Iteration: 1733639681, states[0] = -95.251814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747875625, states[0] = -11.303491, states[40]= 0.002350
Saving checkpoint... 
Iteration: 1762314339, states[0] = -54.447311, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1775652860, states[0] = -95.266573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789055474, states[0] = -95.070374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803346776, states[0] = -95.048387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817817520, states[0] = -95.016044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831447755, states[0] = -95.052244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845763780, states[0] = -94.948707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860263209, states[0] = -94.941869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874580114, states[0] = -2.844557, states[40]= 0.003806
Saving checkpoint... 
Iteration: 1887832299, states[0] = -94.991196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901302867, states[0] = -94.970370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915528009, states[0] = 19.099076, states[40]= 0.006250
Saving checkpoint... 
Iteration: 1929771167, states[0] = -94.940373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944002195, states[0] = 42.793872, states[40]= 0.104694
Saving checkpoint... 
Iteration: 1957458102, states[0] = -95.028053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970753370, states[0] = -94.919100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984976811, states[0] = -95.030638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999399728, states[0] = -95.014233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013481074, states[0] = -95.031063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027325096, states[0] = -94.981995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041591583, states[0] = -11.377166, states[40]= 0.002059
Saving checkpoint... 
Iteration: 2055981731, states[0] = -95.031039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069421987, states[0] = -95.019982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083319800, states[0] = -94.978614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097767244, states[0] = -94.934670, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909173
 - CaMKt in component CaMK (millimolar): 0.007100
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.572924
 - nass in component intracellular_ions (millimolar): 6.572985
 - ki in component intracellular_ions (millimolar): 145.402589
 - kss in component intracellular_ions (millimolar): 145.402570
 - cansr in component intracellular_ions (millimolar): 1.319724
 - cajsr in component intracellular_ions (millimolar): 1.281561
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880128
 - hs in component INa (dimensionless): 0.880123
 - j in component INa (dimensionless): 0.880094
 - hsp in component INa (dimensionless): 0.726070
 - jp in component INa (dimensionless): 0.880075
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709982
 - hLp in component INaL (dimensionless): 0.451852
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620677
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695576
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935484
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329346
 - xs1 in component IKs (dimensionless): 0.241894
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:19:26 (2575): called boinc_finish(0)

</stderr_txt>
]]>


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