𝕏

Task 56001049

Name HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_463_1
Workunit 26595049
Created 3 Jul 2024, 23:16:27 UTC
Sent 4 Jul 2024, 0:39:25 UTC
Report deadline 7 Jul 2024, 10:15:25 UTC
Received 4 Jul 2024, 14:41:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241826
Run time 2 hours 30 min 40 sec
CPU time 2 hours 23 min 47 sec
Validate state Valid
Credit 64.18
Device peak FLOPS 4.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.37 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_463.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_463_1_r65792974_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011608352755_ORdGradInc_k_26-Pueyo_APDR-conf_463_1_r65792974_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.689296
     * GNaL_b in INaL: 0.005515
     * Gto_b in Ito: 0.084581
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032338
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.161778
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.156215
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036386
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14347371, states[0] = -95.037102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28467199, states[0] = -95.039422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42088354, states[0] = -11.683675, states[40]= 0.002021
Saving checkpoint... 
Iteration: 56478694, states[0] = -95.013411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71113517, states[0] = -34.950736, states[40]= 0.000253
Saving checkpoint... 
Iteration: 85810334, states[0] = -94.944467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99931428, states[0] = -94.990894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113808446, states[0] = -94.938536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127565487, states[0] = 4.432208, states[40]= 0.004682
Saving checkpoint... 
Iteration: 141982312, states[0] = -94.995877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156576395, states[0] = -1.356130, states[40]= 0.004058
Saving checkpoint... 
Iteration: 170284961, states[0] = -94.916971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184733950, states[0] = -94.856985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199163908, states[0] = -93.518454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213107533, states[0] = -28.424043, states[40]= 0.000528
Saving checkpoint... 
Iteration: 226905553, states[0] = -94.979251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241264310, states[0] = -94.895824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255827378, states[0] = -94.947091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270204452, states[0] = -94.805556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284612913, states[0] = -33.613687, states[40]= 0.000301
Saving checkpoint... 
Iteration: 298365631, states[0] = -94.965680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312125846, states[0] = -46.656310, states[40]= 0.000046
Saving checkpoint... 
Iteration: 326570564, states[0] = 1.964300, states[40]= 0.004477
Saving checkpoint... 
Iteration: 341204723, states[0] = -94.806007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355036834, states[0] = 16.077514, states[40]= 0.005424
Saving checkpoint... 
Iteration: 369217289, states[0] = -94.829289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383693346, states[0] = -94.782882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397500773, states[0] = 44.106433, states[40]= 0.011334
Saving checkpoint... 
Iteration: 411454634, states[0] = -94.989906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425099738, states[0] = -20.925898, states[40]= 0.000899
Saving checkpoint... 
Iteration: 439578584, states[0] = -2.709405, states[40]= 0.003834
Saving checkpoint... 
Iteration: 453948167, states[0] = -94.988712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468202265, states[0] = -94.801090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481811774, states[0] = -94.937046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495116123, states[0] = -36.750060, states[40]= 0.000199
Saving checkpoint... 
Iteration: 509647481, states[0] = -72.086837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523930378, states[0] = -94.985070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537851532, states[0] = -94.959423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551662431, states[0] = -92.863711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566107330, states[0] = -28.217415, states[40]= 0.000538
Saving checkpoint... 
Iteration: 579862465, states[0] = -94.964189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594173421, states[0] = -94.674751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607110434, states[0] = -31.210154, states[40]= 0.000400
Saving checkpoint... 
Iteration: 621594465, states[0] = -15.869179, states[40]= 0.001352
Saving checkpoint... 
Iteration: 636136016, states[0] = -57.736356, states[40]= 0.000007
Saving checkpoint... 
Iteration: 650702455, states[0] = -94.801350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664510189, states[0] = 22.878177, states[40]= 0.050338
Saving checkpoint... 
Iteration: 678203129, states[0] = -94.802663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692706924, states[0] = -94.810030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707186475, states[0] = -94.767204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721309049, states[0] = -94.935013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734903150, states[0] = -94.978129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749395029, states[0] = -94.975730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762891435, states[0] = -94.974605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777029590, states[0] = 18.466532, states[40]= 0.006144
Saving checkpoint... 
Iteration: 790426363, states[0] = -94.984003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804818784, states[0] = -94.941453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819272743, states[0] = -94.904273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833670489, states[0] = -94.570665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847391640, states[0] = -94.974616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860522478, states[0] = 20.396521, states[40]= 0.008080
Saving checkpoint... 
Iteration: 874858816, states[0] = -94.962457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889449111, states[0] = -94.988610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903866087, states[0] = -94.965463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917260403, states[0] = -94.890915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931613376, states[0] = -34.062204, states[40]= 0.000285
Saving checkpoint... 
Iteration: 945438762, states[0] = -94.986573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959615834, states[0] = -36.465492, states[40]= 0.000207
Saving checkpoint... 
Iteration: 973051725, states[0] = 10.428981, states[40]= 0.004942
Saving checkpoint... 
Iteration: 987099797, states[0] = -20.982232, states[40]= 0.000896
Saving checkpoint... 
Iteration: 1001661727, states[0] = -92.457530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016031306, states[0] = 17.933299, states[40]= 0.005915
Saving checkpoint... 
Iteration: 1029916157, states[0] = -94.981410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042205406, states[0] = -94.806881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056834695, states[0] = -94.950650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071201095, states[0] = -94.798374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085449767, states[0] = -94.988607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098988431, states[0] = -94.994530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113290561, states[0] = -94.920549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127111271, states[0] = -32.019353, states[40]= 0.000365
Saving checkpoint... 
Iteration: 1141238858, states[0] = -94.863116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155037218, states[0] = 15.942207, states[40]= 0.005399
Saving checkpoint... 
Iteration: 1168991462, states[0] = -94.994865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183392961, states[0] = -94.974817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197885561, states[0] = -94.972420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212254789, states[0] = -94.884097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225030841, states[0] = 18.080099, states[40]= 0.005973
Saving checkpoint... 
Iteration: 1239833399, states[0] = -94.949825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254352961, states[0] = -94.959623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268866541, states[0] = -94.965413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282355914, states[0] = -94.960931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296813743, states[0] = -94.937856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310367778, states[0] = -94.965879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324577818, states[0] = -2.213514, states[40]= 0.003919
Saving checkpoint... 
Iteration: 1338854063, states[0] = -94.960068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352637137, states[0] = -59.004583, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1367273965, states[0] = -94.905151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381648698, states[0] = -73.909484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395902504, states[0] = -94.977526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408524632, states[0] = 19.864541, states[40]= 0.007225
Saving checkpoint... 
Iteration: 1422902271, states[0] = -94.977442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437455403, states[0] = -94.989388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452055820, states[0] = 8.755111, states[40]= 0.004884
Saving checkpoint... 
Iteration: 1465925532, states[0] = -94.983384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480501644, states[0] = 47.079647, states[40]= 0.069042
Saving checkpoint... 
Iteration: 1494127375, states[0] = -48.279791, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1508299630, states[0] = -95.116523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522590805, states[0] = -27.713707, states[40]= 0.000556
Saving checkpoint... 
Iteration: 1535243388, states[0] = -94.145217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549631934, states[0] = -82.387854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564017805, states[0] = -60.895867, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1578238006, states[0] = -95.218853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590912713, states[0] = 22.726833, states[40]= 0.030213
Saving checkpoint... 
Iteration: 1604978674, states[0] = -95.262495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619273654, states[0] = -95.109115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633600047, states[0] = -39.918247, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1647615270, states[0] = 21.965215, states[40]= 0.019293
Saving checkpoint... 
Iteration: 1661244690, states[0] = -94.669339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674635770, states[0] = 14.205887, states[40]= 0.006379
Saving checkpoint... 
Iteration: 1688867138, states[0] = -95.093967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703380273, states[0] = -95.266135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717098895, states[0] = -95.165073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731626637, states[0] = 18.168736, states[40]= 0.007758
Saving checkpoint... 
Iteration: 1746149752, states[0] = -94.975651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760054168, states[0] = -95.242972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772967016, states[0] = -95.255206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786869813, states[0] = -6.937113, states[40]= 0.003368
Saving checkpoint... 
Iteration: 1801380469, states[0] = -95.038178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815829639, states[0] = -94.990543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830190976, states[0] = -94.806008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843488523, states[0] = -95.013836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856967079, states[0] = -95.004269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871795030, states[0] = -94.932326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886803170, states[0] = -94.935506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901495972, states[0] = -94.998441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916412360, states[0] = -94.982111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931602976, states[0] = -24.116950, states[40]= 0.000732
Saving checkpoint... 
Iteration: 1946654451, states[0] = -83.587045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961307480, states[0] = -94.933677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976297541, states[0] = -94.926020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991452104, states[0] = -94.988651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006418069, states[0] = -94.981372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021340502, states[0] = -94.953155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035973532, states[0] = -94.991916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050443451, states[0] = -94.986792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065668494, states[0] = -94.426407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080715015, states[0] = -94.824117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095086058, states[0] = -8.257293, states[40]= 0.002704
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.871117
 - CaMKt in component CaMK (millimolar): 0.006901
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.595015
 - nass in component intracellular_ions (millimolar): 6.595075
 - ki in component intracellular_ions (millimolar): 145.383349
 - kss in component intracellular_ions (millimolar): 145.383330
 - cansr in component intracellular_ions (millimolar): 1.308374
 - cajsr in component intracellular_ions (millimolar): 1.270672
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879466
 - hs in component INa (dimensionless): 0.879462
 - j in component INa (dimensionless): 0.879433
 - hsp in component INa (dimensionless): 0.724825
 - jp in component INa (dimensionless): 0.879414
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709587
 - hLp in component INaL (dimensionless): 0.452518
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.623265
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.698578
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937218
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001588
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327071
 - xs1 in component IKs (dimensionless): 0.237443
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:38:01 (8361): called boinc_finish(0)

</stderr_txt>
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