𝕏

Task 56000370

Name HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0
Workunit 26594712
Created 3 Jul 2024, 23:15:56 UTC
Sent 4 Jul 2024, 0:31:13 UTC
Report deadline 7 Jul 2024, 10:07:13 UTC
Received 4 Jul 2024, 14:45:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215737
Run time 1 hours 13 min 57 sec
CPU time 56 min 21 sec
Validate state Valid
Credit 62.33
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.80 MB
Peak swap size 391.88 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.056231
     * GNaL_b in INaL: 0.005520
     * Gto_b in Ito: 0.086506
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031826
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.164813
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.512046
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029076
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 28101348, states[0] = -23.421538, states[40]= 0.000773
Saving checkpoint... 
Iteration: 62229734, states[0] = -94.876953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97140716, states[0] = -60.934892, states[40]= 0.000004
Saving checkpoint... 
Iteration: 122861426, states[0] = -94.980076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146583546, states[0] = -5.299830, states[40]= 0.003326
Saving checkpoint... 
Iteration: 171205972, states[0] = -94.818551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197022523, states[0] = 20.430961, states[40]= 0.007792
Saving checkpoint... 
Iteration: 220995980, states[0] = -95.010557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251040076, states[0] = 15.149073, states[40]= 0.005159


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.056231
     * GNaL_b in INaL: 0.005520
     * Gto_b in Ito: 0.086506
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031826
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.164813
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.512046
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029076
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 251040076
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 15.149073 (After loading)
 - states[40]: 0.005159 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 261573753, states[0] = 0.894100, states[40]= 0.004346
Saving checkpoint... 
Iteration: 285923763, states[0] = -94.997730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308256804, states[0] = -94.898400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326794975, states[0] = -94.936986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344499112, states[0] = -95.010709, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_56_0_r613233500_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.056231
     * GNaL_b in INaL: 0.005520
     * Gto_b in Ito: 0.086506
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031826
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.164813
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.512046
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029076
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 344499112
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.010709 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 347474911, states[0] = -95.007474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360880249, states[0] = -94.984732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378751994, states[0] = -94.892319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391313243, states[0] = -94.950755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419473395, states[0] = -95.007194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449074670, states[0] = 0.391772, states[40]= 0.004286
Saving checkpoint... 
Iteration: 470935228, states[0] = -95.000203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493909406, states[0] = -94.993866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521059427, states[0] = 7.660335, states[40]= 0.004812
Saving checkpoint... 
Iteration: 544959057, states[0] = -95.004781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569779203, states[0] = -94.922658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594502310, states[0] = 41.431353, states[40]= 0.113504
Saving checkpoint... 
Iteration: 622129679, states[0] = -48.414540, states[40]= 0.000036
Saving checkpoint... 
Iteration: 647191663, states[0] = -94.787736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682208809, states[0] = -94.823089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714774941, states[0] = -94.918328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745055228, states[0] = 9.391034, states[40]= 0.004864
Saving checkpoint... 
Iteration: 781474421, states[0] = -95.007102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815636870, states[0] = -56.152960, states[40]= 0.000010
Saving checkpoint... 
Iteration: 842138940, states[0] = -58.454522, states[40]= 0.000007
Saving checkpoint... 
Iteration: 871091741, states[0] = -11.963332, states[40]= 0.001950
Saving checkpoint... 
Iteration: 897402067, states[0] = -94.991500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924920429, states[0] = -94.996457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960273302, states[0] = -94.916484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993268185, states[0] = -94.911042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026324229, states[0] = -94.957501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062666243, states[0] = -93.615177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095475798, states[0] = -95.007093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129433951, states[0] = -94.999476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159622253, states[0] = -40.808197, states[40]= 0.000116
Saving checkpoint... 
Iteration: 1194307495, states[0] = -94.946126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224268655, states[0] = -94.911394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258450052, states[0] = -95.002665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293916290, states[0] = -94.995157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331563094, states[0] = 6.077948, states[40]= 0.004749
Saving checkpoint... 
Iteration: 1364777001, states[0] = -94.919952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403669702, states[0] = -94.353669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439495405, states[0] = -95.009511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474847103, states[0] = -94.969886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509466714, states[0] = -95.049301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544052562, states[0] = -95.228969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576874797, states[0] = -10.550239, states[40]= 0.002512
Saving checkpoint... 
Iteration: 1610077941, states[0] = -95.268484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641443962, states[0] = -94.288546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675871382, states[0] = -7.455205, states[40]= 0.003241
Saving checkpoint... 
Iteration: 1707470698, states[0] = -95.105477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742883081, states[0] = -95.135581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777796817, states[0] = -95.284256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807171656, states[0] = -94.725791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840584599, states[0] = -6.921462, states[40]= 0.002999
Saving checkpoint... 
Iteration: 1875398715, states[0] = -94.997197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909595347, states[0] = -15.412813, states[40]= 0.001410
Saving checkpoint... 
Iteration: 1943770955, states[0] = -94.914298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979391263, states[0] = -94.987695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017568335, states[0] = 3.659100, states[40]= 0.004606
Saving checkpoint... 
Iteration: 2057470231, states[0] = -95.005565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093613518, states[0] = -32.361033, states[40]= 0.000364
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.885440
 - CaMKt in component CaMK (millimolar): 0.007082
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.586913
 - nass in component intracellular_ions (millimolar): 6.586973
 - ki in component intracellular_ions (millimolar): 145.388740
 - kss in component intracellular_ions (millimolar): 145.388721
 - cansr in component intracellular_ions (millimolar): 1.318743
 - cajsr in component intracellular_ions (millimolar): 1.280650
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003624
 - hf in component INa (dimensionless): 0.879716
 - hs in component INa (dimensionless): 0.879711
 - j in component INa (dimensionless): 0.879682
 - hsp in component INa (dimensionless): 0.725293
 - jp in component INa (dimensionless): 0.879662
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709428
 - hLp in component INaL (dimensionless): 0.451355
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621060
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696021
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936028
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001627
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326942
 - xs1 in component IKs (dimensionless): 0.240682
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:43:17 (902): called boinc_finish(0)

</stderr_txt>
]]>


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