𝕏

Task 56000180

Name HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_708_1
Workunit 26594617
Created 3 Jul 2024, 23:15:46 UTC
Sent 4 Jul 2024, 0:30:16 UTC
Report deadline 7 Jul 2024, 10:06:16 UTC
Received 4 Jul 2024, 4:36:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224060
Run time 3 hours 1 min 58 sec
CPU time 58 min
Validate state Valid
Credit 64.61
Device peak FLOPS 6.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.19 MB
Peak swap size 5.59 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_708.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_708_1_r473697066_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011542154378_ORdGradInc_k_26-Pueyo_APDR-conf_708_1_r473697066_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.022773
     * GNaL_b in INaL: 0.005749
     * Gto_b in Ito: 0.082989
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031848
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.165062
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.396492
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033735
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11844925, states[0] = -95.130820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24499983, states[0] = -95.133279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37383390, states[0] = -95.088414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50078942, states[0] = -2.860484, states[40]= 0.003823
Saving checkpoint... 
Iteration: 62936808, states[0] = -95.081060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75578000, states[0] = -1.769595, states[40]= 0.003997
Saving checkpoint... 
Iteration: 88314440, states[0] = -95.024297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100846134, states[0] = -95.039560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113589206, states[0] = -9.735426, states[40]= 0.002388
Saving checkpoint... 
Iteration: 126221274, states[0] = -94.917045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138790189, states[0] = -94.999726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151367070, states[0] = -95.044200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163699368, states[0] = -94.874826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176438703, states[0] = -95.064132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189111921, states[0] = -30.890135, states[40]= 0.000420
Saving checkpoint... 
Iteration: 201486272, states[0] = -95.071582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213137278, states[0] = -57.171093, states[40]= 0.000008
Saving checkpoint... 
Iteration: 225576947, states[0] = -0.731946, states[40]= 0.004144
Saving checkpoint... 
Iteration: 238023824, states[0] = 20.494431, states[40]= 0.007614
Saving checkpoint... 
Iteration: 250537522, states[0] = 16.321473, states[40]= 0.005421
Saving checkpoint... 
Iteration: 259061128, states[0] = 7.121319, states[40]= 0.004828
Saving checkpoint... 
Iteration: 271729581, states[0] = -94.927578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284268130, states[0] = -94.977056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297181614, states[0] = -94.830695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309973582, states[0] = -95.069477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322768318, states[0] = -94.977211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335326610, states[0] = -95.023264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347957598, states[0] = -95.066920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360266808, states[0] = -94.975591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373051009, states[0] = 11.277638, states[40]= 0.004979
Saving checkpoint... 
Iteration: 385712610, states[0] = -94.898992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398642751, states[0] = -63.598131, states[40]= 0.000003
Saving checkpoint... 
Iteration: 410879651, states[0] = -95.047425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423455473, states[0] = -95.066505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436146220, states[0] = -68.075196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448707763, states[0] = -94.890011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461244925, states[0] = -94.949467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473563910, states[0] = 5.897249, states[40]= 0.004770
Saving checkpoint... 
Iteration: 486312291, states[0] = -95.014203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498710286, states[0] = -94.894678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511313650, states[0] = -95.015093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523795954, states[0] = -95.002273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536552288, states[0] = 10.772747, states[40]= 0.004960
Saving checkpoint... 
Iteration: 549338786, states[0] = -95.029821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561980586, states[0] = -95.070304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574449197, states[0] = -95.065292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586977507, states[0] = -95.069860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599472109, states[0] = -95.069071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612123645, states[0] = -42.407060, states[40]= 0.000089
Saving checkpoint... 
Iteration: 624800875, states[0] = -95.006004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637257666, states[0] = -94.965236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649949476, states[0] = -95.065297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658311090, states[0] = -95.013286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670967829, states[0] = -95.068379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683609375, states[0] = -28.424710, states[40]= 0.000537
Saving checkpoint... 
Iteration: 696304403, states[0] = -95.008567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708988595, states[0] = -95.071272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721642227, states[0] = -62.954615, states[40]= 0.000003
Saving checkpoint... 
Iteration: 734123069, states[0] = -41.817902, states[40]= 0.000098
Saving checkpoint... 
Iteration: 746698583, states[0] = -94.871966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759179587, states[0] = -94.820251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771504955, states[0] = 28.791420, states[40]= 0.145041
Saving checkpoint... 
Iteration: 783999729, states[0] = -95.072570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796761117, states[0] = -94.969095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809811949, states[0] = -95.013775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822114857, states[0] = -33.691202, states[40]= 0.000303
Saving checkpoint... 
Iteration: 834849197, states[0] = -95.034778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847383955, states[0] = -95.048639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860102911, states[0] = -22.267555, states[40]= 0.000830
Saving checkpoint... 
Iteration: 872751639, states[0] = -94.957838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885294213, states[0] = -95.000664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897421727, states[0] = -95.059342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910097046, states[0] = -16.691248, states[40]= 0.001254
Saving checkpoint... 
Iteration: 922615780, states[0] = -34.585704, states[40]= 0.000270
Saving checkpoint... 
Iteration: 935455283, states[0] = -95.066160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948077955, states[0] = -1.330277, states[40]= 0.004054
Saving checkpoint... 
Iteration: 960660753, states[0] = -90.710372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973246657, states[0] = -94.951434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985952671, states[0] = -95.065669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998542475, states[0] = 14.535626, states[40]= 0.005182
Saving checkpoint... 
Iteration: 1011034836, states[0] = 17.244546, states[40]= 0.005616
Saving checkpoint... 
Iteration: 1023783479, states[0] = -94.991465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036461499, states[0] = -95.067148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045149240, states[0] = -72.397349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057839810, states[0] = -95.030039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070539925, states[0] = 15.468097, states[40]= 0.005289
Saving checkpoint... 
Iteration: 1083219986, states[0] = -94.911483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091829198, states[0] = -95.024286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104353786, states[0] = -95.036717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116821481, states[0] = -95.019714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129180481, states[0] = -94.824961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141925380, states[0] = -95.060045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154471628, states[0] = -95.068661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166944490, states[0] = -95.064046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179823748, states[0] = -95.021050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192675582, states[0] = -94.779664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205343146, states[0] = -95.031632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218077822, states[0] = -1.249549, states[40]= 0.004067
Saving checkpoint... 
Iteration: 1230638318, states[0] = -58.340070, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1243612610, states[0] = -31.524310, states[40]= 0.000392
Saving checkpoint... 
Iteration: 1256308728, states[0] = -95.011298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269062908, states[0] = 6.344051, states[40]= 0.004792
Saving checkpoint... 
Iteration: 1281669310, states[0] = -94.485991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294254150, states[0] = -94.960656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305534435, states[0] = 17.378811, states[40]= 0.005650
Saving checkpoint... 
Iteration: 1317939093, states[0] = -95.062890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330535134, states[0] = 17.144261, states[40]= 0.005592
Saving checkpoint... 
Iteration: 1343107206, states[0] = -26.354719, states[40]= 0.000636
Saving checkpoint... 
Iteration: 1355977705, states[0] = -95.069419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368462016, states[0] = -95.067030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381117726, states[0] = -36.483234, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1393814512, states[0] = -95.015122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406668594, states[0] = -94.402305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419343050, states[0] = -95.031454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431956662, states[0] = -95.066095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444332671, states[0] = -95.026012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457042932, states[0] = 14.366167, states[40]= 0.005165
Saving checkpoint... 
Iteration: 1469482939, states[0] = -95.070070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482379858, states[0] = -95.046843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495385942, states[0] = -95.048907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507826598, states[0] = 19.196046, states[40]= 0.008020
Saving checkpoint... 
Iteration: 1520421105, states[0] = 20.958319, states[40]= 0.010460
Saving checkpoint... 
Iteration: 1532998706, states[0] = -95.321536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541714494, states[0] = 22.735369, states[40]= 0.022225
Saving checkpoint... 
Iteration: 1554310766, states[0] = 23.858232, states[40]= 0.045020
Saving checkpoint... 
Iteration: 1563634009, states[0] = 15.600237, states[40]= 0.006610
Saving checkpoint... 
Iteration: 1576058702, states[0] = -95.129941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588584726, states[0] = -21.092808, states[40]= 0.000954
Saving checkpoint... 
Iteration: 1601256253, states[0] = -95.120926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613872079, states[0] = -95.174513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626185202, states[0] = -95.205374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638840555, states[0] = -95.295419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648267124, states[0] = -3.496830, states[40]= 0.004151
Saving checkpoint... 
Iteration: 1660789796, states[0] = -95.340515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673617982, states[0] = -95.265862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686175196, states[0] = -95.183738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699065268, states[0] = -95.158564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711612131, states[0] = -52.484940, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1724315242, states[0] = -95.261844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736866690, states[0] = -95.162493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749502677, states[0] = -95.240891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762258359, states[0] = 2.656225, states[40]= 0.005138
Saving checkpoint... 
Iteration: 1774760832, states[0] = -95.317451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787416840, states[0] = 21.905744, states[40]= 0.015628
Saving checkpoint... 
Iteration: 1799940968, states[0] = -95.296605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812779600, states[0] = -95.031811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825537413, states[0] = 15.906041, states[40]= 0.005421
Saving checkpoint... 
Iteration: 1838152186, states[0] = -80.073613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850685829, states[0] = -94.859302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863144332, states[0] = -66.613196, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1875943831, states[0] = -95.070727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888412358, states[0] = -95.061411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901053892, states[0] = 10.067512, states[40]= 0.004939
Saving checkpoint... 
Iteration: 1913590777, states[0] = -11.029842, states[40]= 0.002127
Saving checkpoint... 
Iteration: 1926271661, states[0] = -94.981285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938846317, states[0] = -95.033830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951563096, states[0] = 6.243321, states[40]= 0.004788
Saving checkpoint... 
Iteration: 1964307858, states[0] = -95.010750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977211660, states[0] = -94.896615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989726801, states[0] = -94.922332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002182210, states[0] = -94.832139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014897954, states[0] = -95.052421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027490549, states[0] = -95.070747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040079504, states[0] = -2.295496, states[40]= 0.003898
Saving checkpoint... 
Iteration: 2052844647, states[0] = -95.031842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065423134, states[0] = -95.058936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077943867, states[0] = -95.063337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090392118, states[0] = -95.050491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099271043, states[0] = -94.978883, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.947632
 - CaMKt in component CaMK (millimolar): 0.006877
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.530436
 - nass in component intracellular_ions (millimolar): 6.530496
 - ki in component intracellular_ions (millimolar): 145.448826
 - kss in component intracellular_ions (millimolar): 145.448806
 - cansr in component intracellular_ions (millimolar): 1.305362
 - cajsr in component intracellular_ions (millimolar): 1.267481
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003602
 - hf in component INa (dimensionless): 0.880793
 - hs in component INa (dimensionless): 0.880788
 - j in component INa (dimensionless): 0.880760
 - hsp in component INa (dimensionless): 0.727325
 - jp in component INa (dimensionless): 0.880741
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711243
 - hLp in component INaL (dimensionless): 0.453724
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621871
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696843
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935097
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331120
 - xs1 in component IKs (dimensionless): 0.241598
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:36:18 (1856): called boinc_finish(0)

</stderr_txt>
]]>


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