𝕏

Task 55999618

Name HuVeMOp_20240704011124481931_ORdGradInc_k_26-Pueyo_APDR-conf_849_0
Workunit 26594367
Created 3 Jul 2024, 23:11:43 UTC
Sent 4 Jul 2024, 0:25:27 UTC
Report deadline 7 Jul 2024, 10:01:27 UTC
Received 4 Jul 2024, 10:30:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 59419
Run time 1 hours 39 min 17 sec
CPU time 1 hours 39 min 17 sec
Validate state Valid
Credit 61.59
Device peak FLOPS 4.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.38 MB
Peak swap size 4.58 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011124481931_ORdGradInc_k_26-Pueyo_APDR-conf_849.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011124481931_ORdGradInc_k_26-Pueyo_APDR-conf_849_0_r744376824_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011124481931_ORdGradInc_k_26-Pueyo_APDR-conf_849_0_r744376824_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.980262
     * GNaL_b in INaL: 0.005722
     * Gto_b in Ito: 0.083480
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031359
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167504
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.124472
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028974
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11736268, states[0] = -95.006185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27937269, states[0] = -95.087217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43833505, states[0] = -95.032684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59666055, states[0] = -94.110680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75619081, states[0] = -38.143689, states[40]= 0.000171
Saving checkpoint... 
Iteration: 92066430, states[0] = 4.527022, states[40]= 0.004717
Saving checkpoint... 
Iteration: 108184360, states[0] = -94.821264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124403520, states[0] = -95.035410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140884423, states[0] = -95.028531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154536761, states[0] = 16.493182, states[40]= 0.005482
Saving checkpoint... 
Iteration: 170618959, states[0] = -37.359707, states[40]= 0.000191
Saving checkpoint... 
Iteration: 187188131, states[0] = -94.827304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203406610, states[0] = -95.033975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219807525, states[0] = -94.988757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236703925, states[0] = -94.859853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253193152, states[0] = -94.838050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269666629, states[0] = -93.903060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286275358, states[0] = -94.961713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302797417, states[0] = -94.981037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318950866, states[0] = -95.043648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335396371, states[0] = -95.030696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352137237, states[0] = -56.407679, states[40]= 0.000010
Saving checkpoint... 
Iteration: 368091631, states[0] = -11.642264, states[40]= 0.002019
Saving checkpoint... 
Iteration: 384340359, states[0] = -95.008365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400517447, states[0] = 21.780799, states[40]= 0.012969
Saving checkpoint... 
Iteration: 416676964, states[0] = -94.771855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433228644, states[0] = -94.903067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449044487, states[0] = 13.711088, states[40]= 0.005134
Saving checkpoint... 
Iteration: 465133660, states[0] = -52.465113, states[40]= 0.000019
Saving checkpoint... 
Iteration: 481328450, states[0] = -95.001822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497576538, states[0] = -0.535708, states[40]= 0.004193
Saving checkpoint... 
Iteration: 513762017, states[0] = -94.947561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530439443, states[0] = -95.041307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546512117, states[0] = 22.752630, states[40]= 0.032994
Saving checkpoint... 
Iteration: 562760977, states[0] = -94.946358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578380346, states[0] = -95.025311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593908923, states[0] = -95.034111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602880343, states[0] = -95.025294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619471627, states[0] = -95.046896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635765596, states[0] = -94.951425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652216587, states[0] = -94.882901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668843377, states[0] = -95.009712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685173931, states[0] = -94.711675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701841926, states[0] = -95.008962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718254215, states[0] = -94.938323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734649368, states[0] = -71.579166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750996036, states[0] = -95.050094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767458748, states[0] = -95.044744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783166255, states[0] = -93.792906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793978419, states[0] = -95.047776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810196918, states[0] = -94.845451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826417847, states[0] = -95.036269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842928166, states[0] = -95.038698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859127822, states[0] = -46.232154, states[40]= 0.000051
Saving checkpoint... 
Iteration: 875230312, states[0] = -94.905381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891370581, states[0] = -95.021521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907545657, states[0] = 13.270464, states[40]= 0.005102
Saving checkpoint... 
Iteration: 923491623, states[0] = -95.049447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939938988, states[0] = -95.040956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956230684, states[0] = -94.905903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972530755, states[0] = 18.479104, states[40]= 0.006049
Saving checkpoint... 
Iteration: 989132460, states[0] = -51.163648, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1005316250, states[0] = -94.994024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021483283, states[0] = -95.048303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037640128, states[0] = -59.688946, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1053870000, states[0] = -95.021194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070329146, states[0] = -95.001849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086773909, states[0] = -94.959756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102979697, states[0] = -95.047760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119030796, states[0] = 18.466489, states[40]= 0.006043
Saving checkpoint... 
Iteration: 1135616623, states[0] = -35.062009, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1149785810, states[0] = -94.970848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166228287, states[0] = -94.902039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182556032, states[0] = 9.200353, states[40]= 0.004929
Saving checkpoint... 
Iteration: 1193942020, states[0] = -95.041405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210732938, states[0] = -94.909171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227144741, states[0] = -65.251354, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1243287402, states[0] = -94.972178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259758886, states[0] = -94.943520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276202321, states[0] = -94.855965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292312211, states[0] = -94.991166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308624646, states[0] = -42.957743, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1325021850, states[0] = 20.880763, states[40]= 0.008520
Saving checkpoint... 
Iteration: 1336257947, states[0] = -94.942379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352951647, states[0] = -95.043129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369213574, states[0] = -94.877092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385450274, states[0] = -95.042858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401876188, states[0] = -95.023301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418015939, states[0] = 22.051373, states[40]= 0.016077
Saving checkpoint... 
Iteration: 1434236984, states[0] = -94.914997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450782130, states[0] = -94.967357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466979752, states[0] = -95.047538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483232335, states[0] = -94.908088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499748910, states[0] = -94.931206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515982912, states[0] = -16.880503, states[40]= 0.001369
Saving checkpoint... 
Iteration: 1532211228, states[0] = -49.017116, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1548714599, states[0] = -53.826465, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1564945568, states[0] = -94.569732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581403248, states[0] = -41.077157, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1597644109, states[0] = -94.361494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614234302, states[0] = -95.259296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630914338, states[0] = -54.518482, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1647478819, states[0] = -95.163950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664203662, states[0] = -41.852530, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1680714860, states[0] = -55.226871, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1697396195, states[0] = -95.317711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714026971, states[0] = -71.938130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1730423635, states[0] = 19.661606, states[40]= 0.008863
Saving checkpoint... 
Iteration: 1746736803, states[0] = -89.304066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763471666, states[0] = -7.446576, states[40]= 0.003258
Saving checkpoint... 
Iteration: 1779560218, states[0] = -95.289431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796364876, states[0] = -95.293732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812842308, states[0] = -95.051686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829212982, states[0] = -94.904028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845843353, states[0] = -95.026273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861897526, states[0] = -95.040800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878438455, states[0] = -95.046807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894868209, states[0] = -95.023990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911037906, states[0] = 16.072181, states[40]= 0.005410
Saving checkpoint... 
Iteration: 1927576511, states[0] = -0.570524, states[40]= 0.004190
Saving checkpoint... 
Iteration: 1943891515, states[0] = -95.029086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960260335, states[0] = -94.945296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976970031, states[0] = -95.046110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993053732, states[0] = 10.126748, states[40]= 0.004960
Saving checkpoint... 
Iteration: 2009300087, states[0] = -94.982095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025389079, states[0] = -95.027377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041576651, states[0] = -0.602789, states[40]= 0.004184
Saving checkpoint... 
Iteration: 2058102031, states[0] = -21.290597, states[40]= 0.000895
Saving checkpoint... 
Iteration: 2074272763, states[0] = -94.957952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090709067, states[0] = -94.868328, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.925539
 - CaMKt in component CaMK (millimolar): 0.006992
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.584425
 - nass in component intracellular_ions (millimolar): 6.584485
 - ki in component intracellular_ions (millimolar): 145.392759
 - kss in component intracellular_ions (millimolar): 145.392739
 - cansr in component intracellular_ions (millimolar): 1.314139
 - cajsr in component intracellular_ions (millimolar): 1.276156
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880411
 - hs in component INa (dimensionless): 0.880407
 - j in component INa (dimensionless): 0.880378
 - hsp in component INa (dimensionless): 0.726604
 - jp in component INa (dimensionless): 0.880359
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710527
 - hLp in component INaL (dimensionless): 0.452677
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621207
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696102
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935173
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333196
 - xs1 in component IKs (dimensionless): 0.241568
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:28:14 (27076): called boinc_finish(0)

</stderr_txt>
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