𝕏

Task 55999346

Name HuVeMOp_20240704011045317359_ORdGradInc_k_26-Pueyo_APDR-conf_681_1
Workunit 26594231
Created 3 Jul 2024, 23:11:22 UTC
Sent 4 Jul 2024, 0:19:13 UTC
Report deadline 7 Jul 2024, 9:55:13 UTC
Received 5 Jul 2024, 16:35:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222620
Run time 1 hours 49 min 1 sec
CPU time 1 hours 43 min 14 sec
Validate state Valid
Credit 59.91
Device peak FLOPS 4.41 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 5.46 MB
Peak swap size 32.84 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011045317359_ORdGradInc_k_26-Pueyo_APDR-conf_681.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011045317359_ORdGradInc_k_26-Pueyo_APDR-conf_681_1_r1298675927_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704011045317359_ORdGradInc_k_26-Pueyo_APDR-conf_681_1_r1298675927_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.293222
     * GNaL_b in INaL: 0.005488
     * Gto_b in Ito: 0.085675
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031342
     * GKs_b in IKs: 0.001882
     * GK1_b in IK1: 0.163777
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.204642
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034355
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14639717, states[0] = -65.032118, states[40]= 0.000002
Saving checkpoint... 
Iteration: 34032045, states[0] = 17.513390, states[40]= 0.005709
Saving checkpoint... 
Iteration: 52876825, states[0] = -95.037579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72355743, states[0] = -95.018300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91375644, states[0] = -95.020720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110560418, states[0] = 7.395979, states[40]= 0.004807
Saving checkpoint... 
Iteration: 129418598, states[0] = -95.028828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143746735, states[0] = -94.918042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163976158, states[0] = -95.038389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183256282, states[0] = -94.929107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201743493, states[0] = -94.912238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221304432, states[0] = -94.975047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240037383, states[0] = 16.285512, states[40]= 0.005313
Saving checkpoint... 
Iteration: 259500726, states[0] = 42.397550, states[40]= 0.008640
Saving checkpoint... 
Iteration: 279079602, states[0] = -2.154868, states[40]= 0.003909
Saving checkpoint... 
Iteration: 297993889, states[0] = -95.039819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317455468, states[0] = -95.034076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336465723, states[0] = -95.035795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355811136, states[0] = -94.979633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375340340, states[0] = -94.997325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393732205, states[0] = -94.895227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412680838, states[0] = -94.781583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432355166, states[0] = -95.004522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451564987, states[0] = 5.492147, states[40]= 0.004719
Saving checkpoint... 
Iteration: 470610072, states[0] = -28.424789, states[40]= 0.000548
Saving checkpoint... 
Iteration: 490052955, states[0] = 10.518134, states[40]= 0.004898
Saving checkpoint... 
Iteration: 509976237, states[0] = -95.037288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529138761, states[0] = -57.386320, states[40]= 0.000008
Saving checkpoint... 
Iteration: 548626583, states[0] = -44.417684, states[40]= 0.000067
Saving checkpoint... 
Iteration: 567668745, states[0] = -94.091379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587015947, states[0] = 21.841048, states[40]= 0.015522
Saving checkpoint... 
Iteration: 607173707, states[0] = -94.636502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626552173, states[0] = 10.824392, states[40]= 0.004907
Saving checkpoint... 
Iteration: 646086116, states[0] = -6.694160, states[40]= 0.003024
Saving checkpoint... 
Iteration: 665746748, states[0] = -94.916075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684936505, states[0] = -95.030143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704263637, states[0] = -94.936878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724111348, states[0] = -29.625433, states[40]= 0.000490
Saving checkpoint... 
Iteration: 743907775, states[0] = -95.023132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762497284, states[0] = -95.039907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776902832, states[0] = -95.021711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796601353, states[0] = -20.249955, states[40]= 0.000952
Saving checkpoint... 
Iteration: 816217048, states[0] = -94.869628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836126358, states[0] = -44.187861, states[40]= 0.000070
Saving checkpoint... 
Iteration: 854362967, states[0] = -95.007656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872767497, states[0] = -94.941041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890997337, states[0] = -95.039828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910099476, states[0] = -18.489305, states[40]= 0.001081
Saving checkpoint... 
Iteration: 928999503, states[0] = -95.040059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948126877, states[0] = -44.718061, states[40]= 0.000064
Saving checkpoint... 
Iteration: 967387013, states[0] = -95.016647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986353614, states[0] = -95.003444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005402374, states[0] = -95.021426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025050544, states[0] = 11.456480, states[40]= 0.004927
Saving checkpoint... 
Iteration: 1044701232, states[0] = -94.839297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064176534, states[0] = -94.727692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083278811, states[0] = -94.952498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102877166, states[0] = -95.013092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121089572, states[0] = -9.493442, states[40]= 0.002429
Saving checkpoint... 
Iteration: 1140012573, states[0] = 22.365554, states[40]= 0.029153
Saving checkpoint... 
Iteration: 1159902134, states[0] = -95.021254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179581256, states[0] = -3.218024, states[40]= 0.003724
Saving checkpoint... 
Iteration: 1199257483, states[0] = -94.929373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218415220, states[0] = -95.024807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237407127, states[0] = -95.022625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256886755, states[0] = -95.016368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276020162, states[0] = 21.107444, states[40]= 0.009348
Saving checkpoint... 
Iteration: 1295505031, states[0] = 27.933096, states[40]= 0.149486
Saving checkpoint... 
Iteration: 1315038548, states[0] = 15.883983, states[40]= 0.005251
Saving checkpoint... 
Iteration: 1334260904, states[0] = -94.933328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353846245, states[0] = -94.999680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373146217, states[0] = -66.140810, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1392431610, states[0] = -95.028614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410229403, states[0] = -94.890136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429656257, states[0] = -81.339712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446039082, states[0] = 15.697174, states[40]= 0.005225
Saving checkpoint... 
Iteration: 1461243173, states[0] = -94.910656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483463259, states[0] = -95.034628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505433789, states[0] = 16.238903, states[40]= 0.006548
Saving checkpoint... 
Iteration: 1527461857, states[0] = -95.079790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548487145, states[0] = -95.161173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569339164, states[0] = 13.151203, states[40]= 0.006068
Saving checkpoint... 
Iteration: 1588851463, states[0] = 6.837668, states[40]= 0.005490
Saving checkpoint... 
Iteration: 1607758495, states[0] = 2.732980, states[40]= 0.005128
Saving checkpoint... 
Iteration: 1626851926, states[0] = -95.276751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646760471, states[0] = 1.446020, states[40]= 0.004979
Saving checkpoint... 
Iteration: 1665854697, states[0] = -95.280516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685729501, states[0] = 17.342072, states[40]= 0.007054
Saving checkpoint... 
Iteration: 1705283864, states[0] = -19.936910, states[40]= 0.001053
Saving checkpoint... 
Iteration: 1724493458, states[0] = -30.359466, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1743573279, states[0] = -95.298106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761812560, states[0] = -95.225375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781185341, states[0] = -21.550173, states[40]= 0.000925
Saving checkpoint... 
Iteration: 1800035871, states[0] = 15.560700, states[40]= 0.006269
Saving checkpoint... 
Iteration: 1819938685, states[0] = -95.067857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839682793, states[0] = -94.816554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858359606, states[0] = -95.017977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877244643, states[0] = -94.919623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896060941, states[0] = 7.177304, states[40]= 0.004799
Saving checkpoint... 
Iteration: 1914846862, states[0] = -95.001908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933922504, states[0] = -95.027430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953200396, states[0] = -94.837710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971865944, states[0] = -95.008534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990834671, states[0] = -94.993391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010517554, states[0] = 21.580738, states[40]= 0.012343
Saving checkpoint... 
Iteration: 2029802867, states[0] = -94.972525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049585049, states[0] = -5.885475, states[40]= 0.003196
Saving checkpoint... 
Iteration: 2068634523, states[0] = -52.760504, states[40]= 0.000018
Saving checkpoint... 
Iteration: 2087570556, states[0] = 2.865029, states[40]= 0.004538
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.915169
 - CaMKt in component CaMK (millimolar): 0.007046
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.542771
 - nass in component intracellular_ions (millimolar): 6.542831
 - ki in component intracellular_ions (millimolar): 145.433878
 - kss in component intracellular_ions (millimolar): 145.433858
 - cansr in component intracellular_ions (millimolar): 1.314991
 - cajsr in component intracellular_ions (millimolar): 1.276843
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880232
 - hs in component INa (dimensionless): 0.880227
 - j in component INa (dimensionless): 0.880198
 - hsp in component INa (dimensionless): 0.726265
 - jp in component INa (dimensionless): 0.880179
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710008
 - hLp in component INaL (dimensionless): 0.451619
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620384
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695169
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935164
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329122
 - xs1 in component IKs (dimensionless): 0.242340
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:35:09 (74671): called boinc_finish(0)

</stderr_txt>
]]>


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