𝕏

Task 55998699

Name HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1
Workunit 26593918
Created 3 Jul 2024, 23:07:03 UTC
Sent 4 Jul 2024, 0:15:28 UTC
Report deadline 7 Jul 2024, 0:15:28 UTC
Received 4 Jul 2024, 22:41:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 163832
Run time 2 hours 20 min 55 sec
CPU time 1 hours 58 min 16 sec
Validate state Valid
Credit 44.29
Device peak FLOPS 2.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.246990
     * GNaL_b in INaL: 0.005448
     * Gto_b in Ito: 0.082591
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031372
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.166840
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.628571
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029177
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12435769, states[0] = -94.429164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25048374, states[0] = 32.331341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37545422, states[0] = 32.504844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48554831, states[0] = 29.055166, states[40]= 0.000002
Saving checkpoint... 
Iteration: 56718104, states[0] = -61.626335, states[40]= 0.000484
Saving checkpoint... 
Iteration: 67308836, states[0] = -94.266120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79749468, states[0] = -93.854828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 92107953, states[0] = 4.802719, states[40]= 0.003238
Saving checkpoint... 
Iteration: 103065173, states[0] = 24.115411, states[40]= 0.000022
Saving checkpoint... 
Iteration: 115598325, states[0] = 9.304062, states[40]= 0.001594
Saving checkpoint... 
Iteration: 128132302, states[0] = -12.357210, states[40]= 0.005852
Saving checkpoint... 
Iteration: 140594171, states[0] = 11.152005, states[40]= 0.001117
Saving checkpoint... 
Iteration: 153087612, states[0] = 14.197508, states[40]= 0.000548
Saving checkpoint... 
Iteration: 165422720, states[0] = -94.555972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177704034, states[0] = -56.812609, states[40]= 0.001156
Saving checkpoint... 
Iteration: 190140831, states[0] = -19.091574, states[40]= 0.008975
Saving checkpoint... 
Iteration: 202520893, states[0] = 35.174453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214317113, states[0] = -94.337913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226042665, states[0] = 31.720960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237823188, states[0] = -94.358137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249551765, states[0] = 28.858508, states[40]= 0.000003
Saving checkpoint... 
Iteration: 261361736, states[0] = -94.461449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273369731, states[0] = -94.475912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285419176, states[0] = -94.541907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297469574, states[0] = -94.575225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309222566, states[0] = -78.858088, states[40]= 0.000050
Saving checkpoint... 
Iteration: 321381737, states[0] = -94.491325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333270365, states[0] = -94.067445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 345251338, states[0] = -93.896886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357159532, states[0] = -29.221575, states[40]= 0.019444
Saving checkpoint... 
Iteration: 369065620, states[0] = 23.669612, states[40]= 0.000029
Saving checkpoint... 
Iteration: 381074367, states[0] = 20.036721, states[40]= 0.000105
Saving checkpoint... 
Iteration: 393137203, states[0] = -16.603635, states[40]= 0.006683
Saving checkpoint... 
Iteration: 404908185, states[0] = -94.517393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416758121, states[0] = -93.955434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428692705, states[0] = -48.209870, states[40]= 0.003451
Saving checkpoint... 
Iteration: 440664783, states[0] = -31.681601, states[40]= 0.016890
Saving checkpoint... 
Iteration: 452775154, states[0] = -94.089243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464712328, states[0] = -64.626301, states[40]= 0.000382
Saving checkpoint... 
Iteration: 476656820, states[0] = -27.944575, states[40]= 0.020186
Saving checkpoint... 
Iteration: 486933405, states[0] = -94.532072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493647429, states[0] = -23.183447, states[40]= 0.016233
Saving checkpoint... 
Iteration: 504199106, states[0] = -53.007869, states[40]= 0.001917
Saving checkpoint... 
Iteration: 512885057, states[0] = -94.475324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523847073, states[0] = -94.398688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531542962, states[0] = 31.646477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540694482, states[0] = -49.533626, states[40]= 0.002945
Saving checkpoint... 
Iteration: 550133012, states[0] = -13.419054, states[40]= 0.005889
Saving checkpoint... 
Iteration: 559979266, states[0] = -94.550461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 569654549, states[0] = -26.853176, states[40]= 0.020261
Saving checkpoint... 
Iteration: 576732845, states[0] = -92.495349, states[40]= 0.000003
Saving checkpoint... 
Iteration: 580401366, states[0] = -94.489974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586691387, states[0] = -47.277958, states[40]= 0.003832
Saving checkpoint... 
Iteration: 595490732, states[0] = -94.550753, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.246990
     * GNaL_b in INaL: 0.005448
     * Gto_b in Ito: 0.082591
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031372
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.166840
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.628571
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029177
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 595490732
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.550753 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 607224832, states[0] = -82.939247, states[40]= 0.000028
Saving checkpoint... 
Iteration: 619256476, states[0] = -93.917425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631223139, states[0] = -79.807189, states[40]= 0.000044
Saving checkpoint... 
Iteration: 643281202, states[0] = -94.108994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655271471, states[0] = -94.039755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667172856, states[0] = -35.726352, states[40]= 0.012226
Saving checkpoint... 
Iteration: 679196406, states[0] = -50.948147, states[40]= 0.002476
Saving checkpoint... 
Iteration: 691111894, states[0] = 1.747609, states[40]= 0.005318
Saving checkpoint... 
Iteration: 703133350, states[0] = -13.658120, states[40]= 0.005882
Saving checkpoint... 
Iteration: 715556530, states[0] = 27.186349, states[40]= 0.000006
Saving checkpoint... 
Iteration: 728141172, states[0] = -19.327316, states[40]= 0.009230
Saving checkpoint... 
Iteration: 740734865, states[0] = -93.091550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 748656725, states[0] = -27.878936, states[40]= 0.020128
Saving checkpoint... 
Iteration: 758039547, states[0] = 32.581373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770588852, states[0] = 13.568619, states[40]= 0.000649
Saving checkpoint... 
Iteration: 783213463, states[0] = -65.840204, states[40]= 0.000318
Saving checkpoint... 
Iteration: 795885709, states[0] = -94.444791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 808477432, states[0] = -94.522218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821005272, states[0] = 26.962517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833721164, states[0] = -76.279590, states[40]= 0.000071
Saving checkpoint... 
Iteration: 846467550, states[0] = -94.513588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 859080250, states[0] = 17.493561, states[40]= 0.000226
Saving checkpoint... 
Iteration: 871637389, states[0] = -16.671269, states[40]= 0.006674
Saving checkpoint... 
Iteration: 884189075, states[0] = -45.626037, states[40]= 0.004600
Saving checkpoint... 
Iteration: 896829783, states[0] = -94.307350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909450760, states[0] = -94.497387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922121032, states[0] = -4.165165, states[40]= 0.007058
Saving checkpoint... 
Iteration: 934566086, states[0] = 23.509147, states[40]= 0.000030
Saving checkpoint... 
Iteration: 947067126, states[0] = 23.088710, states[40]= 0.000035
Saving checkpoint... 
Iteration: 959595191, states[0] = 10.568915, states[40]= 0.001291
Saving checkpoint... 
Iteration: 971982309, states[0] = -94.506062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984014390, states[0] = 34.101668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995976375, states[0] = -94.500986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008033775, states[0] = 33.912641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020089403, states[0] = 13.325336, states[40]= 0.000682
Saving checkpoint... 
Iteration: 1032031108, states[0] = 34.399718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043906781, states[0] = -94.444877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055940065, states[0] = -94.473943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067963942, states[0] = -94.487216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079984598, states[0] = -94.494986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091857223, states[0] = -94.359443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103855870, states[0] = -94.355055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115892689, states[0] = -94.419285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127894012, states[0] = -94.419748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139865159, states[0] = -94.370801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147869953, states[0] = -94.379167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159686508, states[0] = -43.875605, states[40]= 0.005540
Saving checkpoint... 
Iteration: 1169617189, states[0] = -1.500315, states[40]= 0.006580
Saving checkpoint... 
Iteration: 1181660824, states[0] = -29.773924, states[40]= 0.018765
Saving checkpoint... 
Iteration: 1193636042, states[0] = -15.629366, states[40]= 0.006166
Saving checkpoint... 
Iteration: 1205835824, states[0] = -94.291531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218056414, states[0] = 27.252549, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1230063866, states[0] = 24.409488, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1242100939, states[0] = 7.741055, states[40]= 0.002241


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704010622855007_ORdGradInc_k_26-Drouin_MID_1000-conf_283_1_r346275013_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.246990
     * GNaL_b in INaL: 0.005448
     * Gto_b in Ito: 0.082591
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031372
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.166840
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.628571
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029177
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1242100939
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 7.741055 (After loading)
 - states[40]: 0.002241 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1251370333, states[0] = -94.368427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262320664, states[0] = -94.234961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273771590, states[0] = -93.971315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284911166, states[0] = -94.423008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295804252, states[0] = -94.163128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306742725, states[0] = -93.664154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317740911, states[0] = -93.610381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328665585, states[0] = -32.025011, states[40]= 0.016317
Saving checkpoint... 
Iteration: 1339498138, states[0] = -94.470841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350098308, states[0] = 9.066963, states[40]= 0.001740
Saving checkpoint... 
Iteration: 1361036712, states[0] = 33.301432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372038984, states[0] = 32.755341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383421660, states[0] = -94.422527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394734069, states[0] = -92.795359, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1406017998, states[0] = 34.971721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417085550, states[0] = 15.131944, states[40]= 0.000425
Saving checkpoint... 
Iteration: 1428109526, states[0] = 3.182193, states[40]= 0.004464
Saving checkpoint... 
Iteration: 1439231340, states[0] = -91.518332, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1450032404, states[0] = 34.194584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461104863, states[0] = 5.727462, states[40]= 0.003145
Saving checkpoint... 
Iteration: 1465890635, states[0] = -94.377533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474380077, states[0] = -94.360535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484300151, states[0] = -94.122275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1493728701, states[0] = -88.979244, states[40]= 0.000010
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.329545
 - CaMKt in component CaMK (millimolar): 0.054701
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 8.553473
 - nass in component intracellular_ions (millimolar): 8.553674
 - ki in component intracellular_ions (millimolar): 142.258059
 - kss in component intracellular_ions (millimolar): 142.258022
 - cansr in component intracellular_ions (millimolar): 2.840008
 - cajsr in component intracellular_ions (millimolar): 2.790036
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.003834
 - hf in component INa (dimensionless): 0.869710
 - hs in component INa (dimensionless): 0.869698
 - j in component INa (dimensionless): 0.869608
 - hsp in component INa (dimensionless): 0.706677
 - jp in component INa (dimensionless): 0.869537
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.670708
 - hLp in component INaL (dimensionless): 0.381006
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.545607
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.606610
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.863124
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999476
 - jca in component ICaL (dimensionless): 0.999925
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006118
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.450858
 - xs1 in component IKs (dimensionless): 0.344849
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997484
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:46:08 (3644): called boinc_finish(0)

</stderr_txt>
]]>


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