𝕏

Task 55996418

Name HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682_0
Workunit 26592801
Created 3 Jul 2024, 22:46:11 UTC
Sent 4 Jul 2024, 0:00:33 UTC
Report deadline 7 Jul 2024, 0:00:33 UTC
Received 5 Jul 2024, 0:35:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220836
Run time 38 min 44 sec
CPU time 33 min 26 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 5.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.77 MB
Peak swap size 392.01 GB
Peak disk usage 0.73 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682_0_r1322185551_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682_0_r1322185551_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.019125
     * GNaL_b in INaL: 0.006007
     * Gto_b in Ito: 0.082391
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031344
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.162847
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.163128
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031157
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 4448815, states[0] = -86.848051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 8424212, states[0] = -86.829790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 12455780, states[0] = -86.857430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16355093, states[0] = -86.763323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 21331720, states[0] = -86.726640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25329283, states[0] = -86.728953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28680068, states[0] = -46.179752, states[40]= 0.000121
Saving checkpoint... 
Iteration: 31662654, states[0] = -31.629332, states[40]= 0.000443
Saving checkpoint... 
Iteration: 36030633, states[0] = 32.309206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39811987, states[0] = -86.714208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42852458, states[0] = -86.808841, states[40]= 0.000002
Saving checkpoint... 
Iteration: 46558620, states[0] = 25.010292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49154735, states[0] = -28.768853, states[40]= 0.000500
Saving checkpoint... 
Iteration: 52665773, states[0] = -38.507956, states[40]= 0.000313
Saving checkpoint... 
Iteration: 56356682, states[0] = -86.835998, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60873628, states[0] = -86.866522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 65048333, states[0] = 27.975264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68348716, states[0] = -86.835393, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72165940, states[0] = -41.037967, states[40]= 0.000261
Saving checkpoint... 
Iteration: 76469609, states[0] = -86.959460, states[40]= 0.000002
Saving checkpoint... 
Iteration: 80272209, states[0] = -86.621848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83697760, states[0] = -81.044580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88032719, states[0] = 31.346969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92269567, states[0] = -86.616658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95344730, states[0] = -86.845249, states[40]= 0.000002
Saving checkpoint... 
Iteration: 99612829, states[0] = -0.537544, states[40]= 0.000105
Saving checkpoint... 
Iteration: 103161498, states[0] = -38.778612, states[40]= 0.000330
Saving checkpoint... 
Iteration: 106836706, states[0] = -86.833450, states[40]= 0.000002
Saving checkpoint... 
Iteration: 110245857, states[0] = -86.496149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115059163, states[0] = 23.989895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119216925, states[0] = -86.282156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123380133, states[0] = -86.906624, states[40]= 0.000002
Saving checkpoint... 
Iteration: 127823579, states[0] = -86.808434, states[40]= 0.000002
Saving checkpoint... 
Iteration: 131358536, states[0] = -86.877261, states[40]= 0.000002
Saving checkpoint... 
Iteration: 136036352, states[0] = 30.566060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140258236, states[0] = -86.571492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144089302, states[0] = 11.256009, states[40]= 0.000013
Saving checkpoint... 
Iteration: 149205988, states[0] = -85.981391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153610581, states[0] = 0.339698, states[40]= 0.000097
Saving checkpoint... 
Iteration: 157343744, states[0] = -86.853114, states[40]= 0.000002
Saving checkpoint... 
Iteration: 162110574, states[0] = 0.319925, states[40]= 0.000097
Saving checkpoint... 
Iteration: 165713996, states[0] = -86.253230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169381367, states[0] = -86.910599, states[40]= 0.000002
Saving checkpoint... 
Iteration: 172277942, states[0] = -86.665011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175779842, states[0] = -86.672769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178632869, states[0] = -16.304684, states[40]= 0.000186
Saving checkpoint... 
Iteration: 182769392, states[0] = -86.627360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187322220, states[0] = -86.806797, states[40]= 0.000002
Saving checkpoint... 
Iteration: 191806711, states[0] = -86.765337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194578981, states[0] = 15.876948, states[40]= 0.000004
Saving checkpoint... 
Iteration: 199057216, states[0] = 24.575196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202194477, states[0] = -79.926950, states[40]= 0.000002
Saving checkpoint... 
Iteration: 205887107, states[0] = -86.916451, states[40]= 0.000002
Saving checkpoint... 
Iteration: 208783514, states[0] = -86.686385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212090858, states[0] = 10.453385, states[40]= 0.000016
Saving checkpoint... 
Iteration: 216369054, states[0] = -86.893095, states[40]= 0.000002
Saving checkpoint... 
Iteration: 220877513, states[0] = -86.904214, states[40]= 0.000002
Saving checkpoint... 
Iteration: 225265792, states[0] = -86.608799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228860863, states[0] = -86.880458, states[40]= 0.000002
Saving checkpoint... 
Iteration: 233343828, states[0] = -86.851195, states[40]= 0.000002
Saving checkpoint... 
Iteration: 237409123, states[0] = -86.937352, states[40]= 0.000002
Saving checkpoint... 
Iteration: 242608003, states[0] = 1.721282, states[40]= 0.000081
Saving checkpoint... 
Iteration: 247189729, states[0] = -72.664776, states[40]= 0.000005
Saving checkpoint... 
Iteration: 250840605, states[0] = -86.844125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 254249744, states[0] = -86.521722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259516959, states[0] = 31.144843, states[40]= -0.000000
Saving checkpoint... 
Iteration: 263287275, states[0] = -86.697980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268333129, states[0] = -86.827952, states[40]= 0.000002
Saving checkpoint... 
Iteration: 273299833, states[0] = -86.740564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277195425, states[0] = -81.186032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281222979, states[0] = -86.335505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284883368, states[0] = -86.908157, states[40]= 0.000002
Saving checkpoint... 
Iteration: 290045656, states[0] = 28.273723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295294753, states[0] = -86.722692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299807064, states[0] = -86.761088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304925015, states[0] = -86.946776, states[40]= 0.000002
Saving checkpoint... 
Iteration: 309406196, states[0] = -86.930842, states[40]= 0.000002
Saving checkpoint... 
Iteration: 312879446, states[0] = -86.901816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 317005999, states[0] = 23.245924, states[40]= -0.000000
Saving checkpoint... 
Iteration: 321131341, states[0] = -15.102916, states[40]= 0.000179
Saving checkpoint... 
Iteration: 325331290, states[0] = -86.820824, states[40]= 0.000002
Saving checkpoint... 
Iteration: 329245167, states[0] = -86.489876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334053579, states[0] = 25.822231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338802399, states[0] = -86.744910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343588673, states[0] = 11.473547, states[40]= 0.000013
Saving checkpoint... 
Iteration: 348576158, states[0] = 17.091934, states[40]= 0.000003
Saving checkpoint... 
Iteration: 353548194, states[0] = 27.535388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358178707, states[0] = -57.603444, states[40]= 0.000040
Saving checkpoint... 
Iteration: 361498793, states[0] = -86.981113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 366208097, states[0] = -86.110247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370978743, states[0] = -86.973284, states[40]= 0.000002
Saving checkpoint... 
Iteration: 374905997, states[0] = -86.926979, states[40]= 0.000002
Saving checkpoint... 
Iteration: 379392696, states[0] = -86.913437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 383699966, states[0] = -84.742335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387960018, states[0] = -86.963804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 391383017, states[0] = -86.901759, states[40]= 0.000002
Saving checkpoint... 
Iteration: 396026467, states[0] = 31.820634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399626427, states[0] = -10.973375, states[40]= 0.000175
Saving checkpoint... 
Iteration: 403234921, states[0] = -86.418050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406953792, states[0] = -86.959477, states[40]= 0.000002
Saving checkpoint... 
Iteration: 410304912, states[0] = -86.748462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413876533, states[0] = -86.892419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 417696521, states[0] = -82.348014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421349020, states[0] = -86.850251, states[40]= 0.000002
Saving checkpoint... 
Iteration: 424716939, states[0] = -86.273779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428720242, states[0] = -86.304005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431990100, states[0] = -86.974196, states[40]= 0.000002
Saving checkpoint... 
Iteration: 436661046, states[0] = -39.511120, states[40]= 0.000315
Saving checkpoint... 
Iteration: 441156360, states[0] = -35.303881, states[40]= 0.000433
Saving checkpoint... 
Iteration: 445778301, states[0] = -86.652441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449715819, states[0] = -86.260669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453645258, states[0] = -26.191884, states[40]= 0.000472
Saving checkpoint... 
Iteration: 458116430, states[0] = -3.412328, states[40]= 0.000140
Saving checkpoint... 
Iteration: 462600379, states[0] = 5.782920, states[40]= 0.000042
Saving checkpoint... 
Iteration: 466118566, states[0] = -4.883801, states[40]= 0.000154
Saving checkpoint... 
Iteration: 469898375, states[0] = -86.914258, states[40]= 0.000002
Saving checkpoint... 
Iteration: 474202039, states[0] = -85.421889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476732433, states[0] = -86.396149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480095532, states[0] = 8.201898, states[40]= 0.000026
Saving checkpoint... 
Iteration: 484066200, states[0] = 21.202077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487314441, states[0] = -86.771001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 492021605, states[0] = 31.819604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496180405, states[0] = -59.581024, states[40]= 0.000031
Saving checkpoint... 
Iteration: 500975336, states[0] = -86.964582, states[40]= 0.000002
Saving checkpoint... 
Iteration: 505178247, states[0] = -57.053979, states[40]= 0.000043
Saving checkpoint... 
Iteration: 509633702, states[0] = -17.063207, states[40]= 0.000193
Saving checkpoint... 
Iteration: 514787301, states[0] = -86.683791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519764674, states[0] = -86.586761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523712306, states[0] = -86.210131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527581328, states[0] = 14.831465, states[40]= 0.000006
Saving checkpoint... 
Iteration: 531822254, states[0] = -86.788331, states[40]= 0.000002
Saving checkpoint... 
Iteration: 536117795, states[0] = -4.338585, states[40]= 0.000149
Saving checkpoint... 
Iteration: 540771825, states[0] = -86.619084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544370123, states[0] = -86.876474, states[40]= 0.000002
Saving checkpoint... 
Iteration: 548035196, states[0] = 30.745538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552185755, states[0] = -66.552682, states[40]= 0.000012
Saving checkpoint... 
Iteration: 556043657, states[0] = 28.826850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560319989, states[0] = -86.781136, states[40]= 0.000002
Saving checkpoint... 
Iteration: 563826685, states[0] = -86.796982, states[40]= 0.000002
Saving checkpoint... 
Iteration: 568559423, states[0] = 23.779878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573242417, states[0] = -86.458390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577926446, states[0] = -86.932492, states[40]= 0.000002
Saving checkpoint... 
Iteration: 582640620, states[0] = -22.600867, states[40]= 0.000335
Saving checkpoint... 
Iteration: 586869303, states[0] = -86.872949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 590182148, states[0] = -61.709512, states[40]= 0.000023
Saving checkpoint... 
Iteration: 593682142, states[0] = -61.701285, states[40]= 0.000023
Saving checkpoint... 
Iteration: 598342799, states[0] = -86.828842, states[40]= 0.000002
Saving checkpoint... 
Iteration: 602135251, states[0] = -18.331977, states[40]= 0.000210
Saving checkpoint... 
Iteration: 606759226, states[0] = -86.554148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611095545, states[0] = 8.199841, states[40]= 0.000026
Saving checkpoint... 
Iteration: 615927693, states[0] = -86.931291, states[40]= 0.000002
Saving checkpoint... 
Iteration: 618424459, states[0] = -86.928757, states[40]= 0.000002
Saving checkpoint... 
Iteration: 621655788, states[0] = -34.788553, states[40]= 0.000445
Saving checkpoint... 
Iteration: 625502929, states[0] = 18.361197, states[40]= 1.324083
Saving checkpoint... 
Iteration: 629277688, states[0] = -86.639402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632611431, states[0] = -0.246606, states[40]= 0.000104
Saving checkpoint... 
Iteration: 635913283, states[0] = -86.918788, states[40]= 0.000002
Saving checkpoint... 
Iteration: 640372971, states[0] = -86.874961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 643128350, states[0] = -12.556885, states[40]= 0.000174
Saving checkpoint... 
Iteration: 647149503, states[0] = -29.528200, states[40]= 0.000524
Saving checkpoint... 
Iteration: 651063566, states[0] = 22.230258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655599831, states[0] = 6.068402, states[40]= 0.000039
Saving checkpoint... 
Iteration: 660010483, states[0] = 28.239461, states[40]= -0.000000
Saving checkpoint... 
Iteration: 663931069, states[0] = -86.930998, states[40]= 0.000002
Saving checkpoint... 
Iteration: 667572550, states[0] = 18.627820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 672508161, states[0] = 26.222506, states[40]= -0.000000
Saving checkpoint... 
Iteration: 677497245, states[0] = -86.962896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 682153915, states[0] = -33.175539, states[40]= 0.000484
Saving checkpoint... 
Iteration: 685733189, states[0] = -86.389397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690679924, states[0] = -58.974415, states[40]= 0.000033
Saving checkpoint... 
Iteration: 695663985, states[0] = -42.242936, states[40]= 0.000244
Saving checkpoint... 
Iteration: 700382702, states[0] = -86.883992, states[40]= 0.000002
Saving checkpoint... 
Iteration: 704183448, states[0] = -63.362178, states[40]= 0.000018
Saving checkpoint... 
Iteration: 707540259, states[0] = 29.684141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712300820, states[0] = -86.718745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 716331012, states[0] = -86.798084, states[40]= 0.000002
Saving checkpoint... 
Iteration: 720384921, states[0] = -86.885505, states[40]= 0.000002
Saving checkpoint... 
Iteration: 724712989, states[0] = -86.208774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728699455, states[0] = -84.451701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731840574, states[0] = -86.816994, states[40]= 0.000002
Saving checkpoint... 
Iteration: 736172146, states[0] = -50.391860, states[40]= 0.000100
Saving checkpoint... 
Iteration: 740254375, states[0] = -86.520255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743874271, states[0] = -86.870872, states[40]= 0.000002
Saving checkpoint... 
Iteration: 748436902, states[0] = -86.930219, states[40]= 0.000002
Saving checkpoint... 
Iteration: 753293861, states[0] = -86.693558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756689899, states[0] = -72.829155, states[40]= 0.000005
Saving checkpoint... 
Iteration: 760674645, states[0] = -53.033429, states[40]= 0.000072
Saving checkpoint... 
Iteration: 764790811, states[0] = -86.682261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768798348, states[0] = -86.707620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 772674239, states[0] = -52.595950, states[40]= 0.000076
Saving checkpoint... 
Iteration: 776941627, states[0] = -86.931636, states[40]= 0.000002
Saving checkpoint... 
Iteration: 780487215, states[0] = -86.953624, states[40]= 0.000002
Saving checkpoint... 
Iteration: 785587979, states[0] = 11.808960, states[40]= 0.000012
Saving checkpoint... 
Iteration: 789599938, states[0] = 6.018948, states[40]= 0.000040
Saving checkpoint... 
Iteration: 792920654, states[0] = -86.916008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 796534536, states[0] = 30.869425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800388146, states[0] = -86.884703, states[40]= 0.000002
Saving checkpoint... 
Iteration: 804564742, states[0] = 21.780097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 808667357, states[0] = -45.512324, states[40]= 0.000174
Saving checkpoint... 
Iteration: 811746436, states[0] = -86.469794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816199290, states[0] = -84.352311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819819020, states[0] = -86.764013, states[40]= 0.000002
Saving checkpoint... 
Iteration: 823425105, states[0] = -86.917738, states[40]= 0.000002
Saving checkpoint... 
Iteration: 826719158, states[0] = -86.271158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831013488, states[0] = 29.979511, states[40]= -0.000000
Saving checkpoint... 
Iteration: 835679860, states[0] = -58.875833, states[40]= 0.000034
Saving checkpoint... 
Iteration: 839883765, states[0] = -86.877411, states[40]= 0.000002
Saving checkpoint... 
Iteration: 844463066, states[0] = -86.939733, states[40]= 0.000002
Saving checkpoint... 
Iteration: 848712894, states[0] = -86.199897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853495352, states[0] = -86.952424, states[40]= 0.000002
Saving checkpoint... 
Iteration: 857919979, states[0] = -86.911837, states[40]= 0.000002
Saving checkpoint... 
Iteration: 862279420, states[0] = -86.633231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866489563, states[0] = -86.949672, states[40]= 0.000002
Saving checkpoint... 
Iteration: 870274062, states[0] = -86.610123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875091854, states[0] = 9.989257, states[40]= 0.000018
Saving checkpoint... 
Iteration: 879448250, states[0] = -86.929866, states[40]= 0.000002
Saving checkpoint... 
Iteration: 883475815, states[0] = -86.943346, states[40]= 0.000002
Saving checkpoint... 
Iteration: 887184116, states[0] = -64.213549, states[40]= 0.000016
Saving checkpoint... 
Iteration: 891052475, states[0] = 26.200553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895157024, states[0] = -35.841258, states[40]= 0.000416
Saving checkpoint... 
Iteration: 900343715, states[0] = -86.813492, states[40]= 0.000002
Saving checkpoint... 
Iteration: 904500255, states[0] = -55.583807, states[40]= 0.000004
Saving checkpoint... 
Iteration: 908135361, states[0] = -18.395367, states[40]= 0.000211
Saving checkpoint... 
Iteration: 912940639, states[0] = -86.923383, states[40]= 0.000002
Saving checkpoint... 
Iteration: 917825403, states[0] = -86.773972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 921808908, states[0] = -86.731072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925468244, states[0] = -86.937667, states[40]= 0.000002
Saving checkpoint... 
Iteration: 930388812, states[0] = -86.878172, states[40]= 0.000002
Saving checkpoint... 
Iteration: 935607719, states[0] = 1.904385, states[40]= 0.000078
Saving checkpoint... 
Iteration: 939701102, states[0] = -85.105545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943462440, states[0] = -86.933883, states[40]= 0.000002
Saving checkpoint... 
Iteration: 948555299, states[0] = 25.252248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952422824, states[0] = -86.908763, states[40]= 0.000002
Saving checkpoint... 
Iteration: 956628759, states[0] = -12.873578, states[40]= 0.000174
Saving checkpoint... 
Iteration: 960601708, states[0] = 5.119906, states[40]= 0.000047
Saving checkpoint... 
Iteration: 964443740, states[0] = -86.922435, states[40]= 0.000002
Saving checkpoint... 
Iteration: 969350393, states[0] = -86.821724, states[40]= 0.000002
Saving checkpoint... 
Iteration: 972854153, states[0] = -86.827948, states[40]= 0.000002
Saving checkpoint... 
Iteration: 977255800, states[0] = -86.514468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982349200, states[0] = -86.818891, states[40]= 0.000002
Saving checkpoint... 
Iteration: 985576784, states[0] = 16.837785, states[40]= 0.000003
Saving checkpoint... 
Iteration: 988952391, states[0] = -86.926071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 992513477, states[0] = 29.977834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997916677, states[0] = -86.901301, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1002456418, states[0] = -86.927487, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1006941590, states[0] = -86.918713, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1010266166, states[0] = -86.565822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013967442, states[0] = -86.932313, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1018209432, states[0] = -86.115565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021121961, states[0] = -7.349818, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1025082022, states[0] = 14.534099, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1028899400, states[0] = -86.883866, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1032610311, states[0] = 0.433224, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1036745034, states[0] = -86.448149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041201602, states[0] = -85.246894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046225858, states[0] = -86.313827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050667680, states[0] = -45.804720, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1054919301, states[0] = -86.900247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1059206673, states[0] = -85.990602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062108380, states[0] = 1.540098, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1065842242, states[0] = -86.801351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1070799765, states[0] = -86.695002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074301797, states[0] = -86.701202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078214542, states[0] = -86.208758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083267290, states[0] = -86.567037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087686803, states[0] = -67.954652, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1092627230, states[0] = -11.581780, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1096998814, states[0] = -86.939932, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1101594128, states[0] = 8.904835, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1106340863, states[0] = -86.796380, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1111699529, states[0] = -84.433081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115897547, states[0] = -86.877089, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1119053584, states[0] = 25.838204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123666245, states[0] = -44.380042, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1128744324, states[0] = -86.438366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132964875, states[0] = -86.924431, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1137532470, states[0] = 31.212937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142233463, states[0] = -86.364863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145987299, states[0] = -86.933220, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1150509573, states[0] = 27.544319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154662949, states[0] = -41.210041, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1159317149, states[0] = -86.739981, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1162951317, states[0] = -86.915742, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1167940062, states[0] = -86.908744, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1173009838, states[0] = 27.759767, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1177578940, states[0] = 15.904542, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1181823886, states[0] = -86.755436, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185609546, states[0] = 0.883166, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1190258437, states[0] = -86.516426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195314962, states[0] = -86.732201, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1199745392, states[0] = -86.440939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203401568, states[0] = -86.876199, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1207307345, states[0] = -86.710340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211019048, states[0] = 31.569360, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1215744509, states[0] = -86.434497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219932398, states[0] = -86.900735, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1224875108, states[0] = -86.844886, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1229553924, states[0] = 25.726584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233200780, states[0] = -84.958971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236908588, states[0] = -86.880902, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1242099660, states[0] = 6.175922, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1246630451, states[0] = -14.273926, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1250767242, states[0] = -86.557208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254641245, states[0] = -23.028826, states[40]= 0.000349
Saving checkpoint... 
Iteration: 1259676604, states[0] = -55.097476, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1263221139, states[0] = -86.262921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267373862, states[0] = -86.840863, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1271614085, states[0] = -1.839658, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1275640704, states[0] = -22.608266, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1280198604, states[0] = -83.873500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284434922, states[0] = -86.898853, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1289093018, states[0] = 9.445434, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1293974132, states[0] = -86.919652, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1298106487, states[0] = 2.599983, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1302659432, states[0] = -37.947580, states[40]= 0.000354
Saving checkpoint... 
Iteration: 1306196209, states[0] = -81.830115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310179041, states[0] = -57.842121, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1314110685, states[0] = 0.228729, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1318110608, states[0] = 0.274036, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1321871626, states[0] = -86.834755, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1326778791, states[0] = -86.604091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330909998, states[0] = -86.876895, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1335698243, states[0] = -83.619342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340175380, states[0] = -53.746470, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1345237903, states[0] = -86.383941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349635531, states[0] = -18.496225, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1353733308, states[0] = -86.351472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357898377, states[0] = -86.864337, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1360859667, states[0] = -86.815014, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1365054802, states[0] = 25.432029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367550170, states[0] = 26.951683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372283911, states[0] = -86.622003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375631531, states[0] = -15.172300, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1379899663, states[0] = -86.864423, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1382912136, states[0] = -86.875873, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1386210171, states[0] = -86.113276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389587848, states[0] = 11.886774, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1394345815, states[0] = -86.789537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1398536510, states[0] = 30.515182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402027915, states[0] = 31.747487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406197066, states[0] = -82.655141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409960566, states[0] = -86.906821, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1413553428, states[0] = 25.897056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418430567, states[0] = -86.888333, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1422151090, states[0] = -30.749467, states[40]= 0.000514
Saving checkpoint... 
Iteration: 1426722738, states[0] = -86.266720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430777353, states[0] = -86.592164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434666284, states[0] = -44.382270, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1438609745, states[0] = 0.780825, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1442065431, states[0] = 21.526028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446255041, states[0] = -86.483296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450987372, states[0] = -86.916163, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1455739439, states[0] = -86.387855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459085794, states[0] = 12.835562, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1463603509, states[0] = 4.201619, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1468416108, states[0] = -86.874425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1473097197, states[0] = 7.415543, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1477103552, states[0] = 4.179411, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1480862235, states[0] = -86.812244, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1484923942, states[0] = -86.879764, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1489321567, states[0] = -86.732426, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492558227, states[0] = 24.234124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495532891, states[0] = 31.157311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498735458, states[0] = -86.358259, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.793668
 - CaMKt in component CaMK (millimolar): 0.025031
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.029952
 - nass in component intracellular_ions (millimolar): 8.030104
 - ki in component intracellular_ions (millimolar): 143.360234
 - kss in component intracellular_ions (millimolar): 143.360196
 - cansr in component intracellular_ions (millimolar): 2.044276
 - cajsr in component intracellular_ions (millimolar): 1.978818
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008190
 - hf in component INa (dimensionless): 0.659298
 - hs in component INa (dimensionless): 0.659267
 - j in component INa (dimensionless): 0.659091
 - hsp in component INa (dimensionless): 0.411200
 - jp in component INa (dimensionless): 0.658964
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.455128
 - hLp in component INaL (dimensionless): 0.221027
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.531872
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.575212
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.875677
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999600
 - jca in component ICaL (dimensionless): 0.999938
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003816
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.511185
 - xs1 in component IKs (dimensionless): 0.336015
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997033
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
03:54:43 (82218): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682_0_r1322185551_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704004542165173_ORdGradInc_k_26-BASE_MID-conf_682_0_r1322185551_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.019125
     * GNaL_b in INaL: 0.006007
     * Gto_b in Ito: 0.082391
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031344
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.162847
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.163128
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031157
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498735458
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.358259 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.793668
 - CaMKt in component CaMK (millimolar): 0.025031
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.029952
 - nass in component intracellular_ions (millimolar): 8.030104
 - ki in component intracellular_ions (millimolar): 143.360234
 - kss in component intracellular_ions (millimolar): 143.360196
 - cansr in component intracellular_ions (millimolar): 2.044276
 - cajsr in component intracellular_ions (millimolar): 1.978818
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008190
 - hf in component INa (dimensionless): 0.659298
 - hs in component INa (dimensionless): 0.659267
 - j in component INa (dimensionless): 0.659091
 - hsp in component INa (dimensionless): 0.411200
 - jp in component INa (dimensionless): 0.658964
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.455128
 - hLp in component INaL (dimensionless): 0.221027
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.531872
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.575212
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.875677
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999600
 - jca in component ICaL (dimensionless): 0.999938
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003816
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.511185
 - xs1 in component IKs (dimensionless): 0.336015
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997033
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
03:57:50 (83320): called boinc_finish(0)

</stderr_txt>
]]>


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