𝕏

Task 55995593

Name HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_182_0
Workunit 26592407
Created 3 Jul 2024, 22:31:56 UTC
Sent 3 Jul 2024, 23:54:10 UTC
Report deadline 7 Jul 2024, 9:30:10 UTC
Received 4 Jul 2024, 3:47:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240274
Run time 2 hours 39 min 33 sec
CPU time 2 hours 37 min 59 sec
Validate state Valid
Credit 61.02
Device peak FLOPS 2.95 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.61 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_182.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_182_0_r1686441644_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_182_0_r1686441644_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.910646
     * GNaL_b in INaL: 0.006128
     * Gto_b in Ito: 0.081650
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032355
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.166224
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.127140
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031469
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13505521, states[0] = 27.227018, states[40]= 0.135093
Saving checkpoint... 
Iteration: 26474599, states[0] = -95.106841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39921610, states[0] = -95.079557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53379452, states[0] = -95.056576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66914422, states[0] = -95.060004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80337688, states[0] = -95.027046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93936510, states[0] = -95.057402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107370154, states[0] = -95.036460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120850707, states[0] = -95.026917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133928042, states[0] = -95.051282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147438165, states[0] = -95.052804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158338959, states[0] = -95.019297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169949016, states[0] = -95.054266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182915528, states[0] = -95.046841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195917925, states[0] = -95.047283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208891875, states[0] = -95.039959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221353867, states[0] = -95.025630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234313837, states[0] = -95.003747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247254221, states[0] = -94.949901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260327086, states[0] = -95.011861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273339219, states[0] = -95.018458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286322772, states[0] = -95.009271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299195132, states[0] = -94.854054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311518291, states[0] = 21.875290, states[40]= 0.011689
Saving checkpoint... 
Iteration: 321100880, states[0] = -20.469485, states[40]= 0.000937
Saving checkpoint... 
Iteration: 333923428, states[0] = -95.048208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346887364, states[0] = -95.038228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359800088, states[0] = -94.993866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372908579, states[0] = -95.044475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385772807, states[0] = -94.970126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398606248, states[0] = -25.587472, states[40]= 0.000677
Saving checkpoint... 
Iteration: 410857656, states[0] = -95.027028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423783396, states[0] = -94.980095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436679116, states[0] = -94.809468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449590956, states[0] = -11.163896, states[40]= 0.002110
Saving checkpoint... 
Iteration: 462454749, states[0] = -95.054448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475393464, states[0] = -95.040075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488299226, states[0] = -94.993129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500323499, states[0] = -95.009553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513248795, states[0] = -94.942947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526188060, states[0] = -94.838750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539131589, states[0] = -51.163947, states[40]= 0.000023
Saving checkpoint... 
Iteration: 551936125, states[0] = -95.050855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564782881, states[0] = -94.979545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578084898, states[0] = -6.115998, states[40]= 0.003172
Saving checkpoint... 
Iteration: 591052733, states[0] = 10.671825, states[40]= 0.004979
Saving checkpoint... 
Iteration: 604570127, states[0] = 2.970917, states[40]= 0.004591
Saving checkpoint... 
Iteration: 618167307, states[0] = -94.304153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631671108, states[0] = -94.657073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645194828, states[0] = -94.853197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658428202, states[0] = -95.049088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671609290, states[0] = -28.494856, states[40]= 0.000538
Saving checkpoint... 
Iteration: 684913678, states[0] = -95.045610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697819938, states[0] = -95.007260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711222179, states[0] = -94.904007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724704253, states[0] = -94.871891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738153400, states[0] = -80.209657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751565428, states[0] = 5.237716, states[40]= 0.004756
Saving checkpoint... 
Iteration: 765044797, states[0] = 13.768189, states[40]= 0.005131
Saving checkpoint... 
Iteration: 778662915, states[0] = -92.899603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791628186, states[0] = -47.440315, states[40]= 0.000042
Saving checkpoint... 
Iteration: 805052936, states[0] = 10.590324, states[40]= 0.004976
Saving checkpoint... 
Iteration: 818513770, states[0] = 22.690515, states[40]= 0.023337
Saving checkpoint... 
Iteration: 831735604, states[0] = -94.924785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845281835, states[0] = -94.978426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858775844, states[0] = -94.972808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872154368, states[0] = -81.938098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885482371, states[0] = -95.058422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898825673, states[0] = -95.010595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912289846, states[0] = -94.985371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925800157, states[0] = -94.993563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939337809, states[0] = -95.017283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952677959, states[0] = -94.801662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966100268, states[0] = -19.884885, states[40]= 0.000976
Saving checkpoint... 
Iteration: 979513161, states[0] = 22.802749, states[40]= 0.026303
Saving checkpoint... 
Iteration: 992479837, states[0] = -95.058011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006042658, states[0] = 14.574281, states[40]= 0.005197
Saving checkpoint... 
Iteration: 1019517463, states[0] = 22.032408, states[40]= 0.012918
Saving checkpoint... 
Iteration: 1033094385, states[0] = -14.305520, states[40]= 0.001569
Saving checkpoint... 
Iteration: 1046600962, states[0] = -20.546835, states[40]= 0.000932
Saving checkpoint... 
Iteration: 1060003850, states[0] = 32.894388, states[40]= 0.150786
Saving checkpoint... 
Iteration: 1073477139, states[0] = -95.057585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086470604, states[0] = -95.056626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099834317, states[0] = -95.015332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113379354, states[0] = -95.035041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126850439, states[0] = -95.023364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140284104, states[0] = -94.980279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153650171, states[0] = -74.690893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167098832, states[0] = -18.515292, states[40]= 0.001081
Saving checkpoint... 
Iteration: 1180565249, states[0] = 5.320629, states[40]= 0.004761
Saving checkpoint... 
Iteration: 1193495394, states[0] = -95.059876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207029640, states[0] = 19.041739, states[40]= 0.006216
Saving checkpoint... 
Iteration: 1220426116, states[0] = -95.048270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233878571, states[0] = -95.034691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247335021, states[0] = -95.015618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260840549, states[0] = -95.018492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274265208, states[0] = -94.961705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286943361, states[0] = -95.051847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300191755, states[0] = -94.846371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313664126, states[0] = -93.472204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327106188, states[0] = -25.529665, states[40]= 0.000679
Saving checkpoint... 
Iteration: 1340623552, states[0] = -42.536755, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1354144952, states[0] = -67.022539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1367643588, states[0] = -65.230342, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1380512795, states[0] = 22.873020, states[40]= 0.028338
Saving checkpoint... 
Iteration: 1393926583, states[0] = -95.048269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407447314, states[0] = -95.052523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420809706, states[0] = -95.000131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434247608, states[0] = -94.940852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447719601, states[0] = -94.899230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461274645, states[0] = -94.971269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474759096, states[0] = -94.954793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487458691, states[0] = -95.054486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500951128, states[0] = 8.320988, states[40]= 0.005474
Saving checkpoint... 
Iteration: 1514525298, states[0] = -66.624166, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1528102692, states[0] = -95.197864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541567356, states[0] = -95.131352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554859105, states[0] = -95.289446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568273683, states[0] = -95.158417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581440069, states[0] = -93.087276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594889230, states[0] = -26.167521, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1608320690, states[0] = 20.868362, states[40]= 0.010599
Saving checkpoint... 
Iteration: 1621674600, states[0] = -95.167460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635081160, states[0] = -17.422313, states[40]= 0.001318
Saving checkpoint... 
Iteration: 1648532063, states[0] = 16.431895, states[40]= 0.006860
Saving checkpoint... 
Iteration: 1661966183, states[0] = -95.308178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675137646, states[0] = -95.278684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688322386, states[0] = -95.258648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701705134, states[0] = -44.179504, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1715157678, states[0] = 3.094265, states[40]= 0.005214
Saving checkpoint... 
Iteration: 1728499268, states[0] = -95.220958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741949001, states[0] = -95.002208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755406142, states[0] = -45.382821, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1768695411, states[0] = -95.213667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781674245, states[0] = -95.315295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795026019, states[0] = -71.878948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1808553570, states[0] = 9.350983, states[40]= 0.005015
Saving checkpoint... 
Iteration: 1821953778, states[0] = -95.088729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835321857, states[0] = -95.031870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848907033, states[0] = -95.059264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862378021, states[0] = -95.044914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875194622, states[0] = -94.859502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888647331, states[0] = -70.884835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1902023479, states[0] = 20.703297, states[40]= 0.007738
Saving checkpoint... 
Iteration: 1915409427, states[0] = -95.045958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928920567, states[0] = -95.048010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942258431, states[0] = -94.954731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955618701, states[0] = -37.673541, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1969022390, states[0] = 20.995929, states[40]= 0.008239
Saving checkpoint... 
Iteration: 1981943422, states[0] = -95.051695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995339377, states[0] = -95.017601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008669187, states[0] = -94.528832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022059293, states[0] = 7.958946, states[40]= 0.004886
Saving checkpoint... 
Iteration: 2035496776, states[0] = -95.059529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048681870, states[0] = -94.820819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062137323, states[0] = -57.641054, states[40]= 0.000008
Saving checkpoint... 
Iteration: 2075090284, states[0] = -10.567584, states[40]= 0.002227
Saving checkpoint... 
Iteration: 2088616726, states[0] = -35.681682, states[40]= 0.000237
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.935680
 - CaMKt in component CaMK (millimolar): 0.006929
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583397
 - nass in component intracellular_ions (millimolar): 6.583457
 - ki in component intracellular_ions (millimolar): 145.394797
 - kss in component intracellular_ions (millimolar): 145.394777
 - cansr in component intracellular_ions (millimolar): 1.309869
 - cajsr in component intracellular_ions (millimolar): 1.271989
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003606
 - hf in component INa (dimensionless): 0.880586
 - hs in component INa (dimensionless): 0.880582
 - j in component INa (dimensionless): 0.880554
 - hsp in component INa (dimensionless): 0.726936
 - jp in component INa (dimensionless): 0.880535
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711072
 - hLp in component INaL (dimensionless): 0.453811
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622189
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697164
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934809
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001596
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331756
 - xs1 in component IKs (dimensionless): 0.241588
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997328
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:47:45 (15348): called boinc_finish(0)

</stderr_txt>
]]>


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