𝕏

Task 55995230

Name HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_369_1
Workunit 26592225
Created 3 Jul 2024, 22:31:40 UTC
Sent 3 Jul 2024, 23:50:56 UTC
Report deadline 7 Jul 2024, 9:26:56 UTC
Received 4 Jul 2024, 23:09:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238613
Run time 1 hours 36 min 53 sec
CPU time 1 hours 36 min 14 sec
Validate state Valid
Credit 61.74
Device peak FLOPS 4.06 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.14 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_369.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_369_1_r1433052511_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_369_1_r1433052511_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.557101
     * GNaL_b in INaL: 0.005756
     * Gto_b in Ito: 0.086747
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032144
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.164165
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.711097
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036838
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16557749, states[0] = 7.124830, states[40]= 0.004792
Saving checkpoint... 
Iteration: 33479861, states[0] = -95.087192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50123210, states[0] = -43.544250, states[40]= 0.000076
Saving checkpoint... 
Iteration: 66725280, states[0] = -94.910041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83428321, states[0] = -95.045469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100080201, states[0] = -2.972756, states[40]= 0.003768
Saving checkpoint... 
Iteration: 116717510, states[0] = -94.885079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133441940, states[0] = -95.041354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150184744, states[0] = -94.815567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166768489, states[0] = -94.952784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183302061, states[0] = -94.982431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199954753, states[0] = -95.041933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216574311, states[0] = 0.732232, states[40]= 0.004314
Saving checkpoint... 
Iteration: 233373368, states[0] = -95.020423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250006636, states[0] = 24.924329, states[40]= 0.113760
Saving checkpoint... 
Iteration: 266594298, states[0] = -14.145640, states[40]= 0.001581
Saving checkpoint... 
Iteration: 283598601, states[0] = -18.194984, states[40]= 0.001101
Saving checkpoint... 
Iteration: 300301689, states[0] = -94.981614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316787499, states[0] = -94.970126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333401929, states[0] = -95.029628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350281437, states[0] = -94.964671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366935313, states[0] = -95.037810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383389532, states[0] = -95.025830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400230097, states[0] = -94.902272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416695303, states[0] = -94.838834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433194103, states[0] = -94.836304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449741303, states[0] = -94.918757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466482002, states[0] = -95.045673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483766194, states[0] = -94.949349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500615441, states[0] = -34.232744, states[40]= 0.000285
Saving checkpoint... 
Iteration: 517253006, states[0] = -94.934081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534000715, states[0] = 42.258313, states[40]= 0.007754
Saving checkpoint... 
Iteration: 551204436, states[0] = -94.857143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567839491, states[0] = -95.005126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584481186, states[0] = -95.045485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601393024, states[0] = -95.026790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618126247, states[0] = -45.041439, states[40]= 0.000060
Saving checkpoint... 
Iteration: 634674703, states[0] = -94.729292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651103630, states[0] = -22.965203, states[40]= 0.000795
Saving checkpoint... 
Iteration: 667745925, states[0] = -94.924903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684563699, states[0] = 5.943017, states[40]= 0.004733
Saving checkpoint... 
Iteration: 701046278, states[0] = 12.994679, states[40]= 0.004985
Saving checkpoint... 
Iteration: 717449747, states[0] = -95.040410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734000701, states[0] = 41.792863, states[40]= 0.006906
Saving checkpoint... 
Iteration: 750811634, states[0] = -94.988423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767379567, states[0] = -95.022220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783972211, states[0] = -95.044078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801130066, states[0] = -49.093746, states[40]= 0.000032
Saving checkpoint... 
Iteration: 818108057, states[0] = -27.166556, states[40]= 0.000598
Saving checkpoint... 
Iteration: 834756108, states[0] = -94.937647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851235080, states[0] = -94.909548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868029503, states[0] = 18.725199, states[40]= 0.006042
Saving checkpoint... 
Iteration: 884630373, states[0] = -49.424266, states[40]= 0.000030
Saving checkpoint... 
Iteration: 901103161, states[0] = -22.520262, states[40]= 0.000817
Saving checkpoint... 
Iteration: 917616157, states[0] = -34.925265, states[40]= 0.000260
Saving checkpoint... 
Iteration: 934560264, states[0] = 7.437074, states[40]= 0.004795
Saving checkpoint... 
Iteration: 951187032, states[0] = -94.819966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967783724, states[0] = -94.966350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984422803, states[0] = -95.034624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001077790, states[0] = -1.264640, states[40]= 0.004045
Saving checkpoint... 
Iteration: 1017621971, states[0] = -40.655270, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1034273902, states[0] = -94.956987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050911600, states[0] = -95.031800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067758720, states[0] = -94.940580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084300100, states[0] = -94.979882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100744070, states[0] = -94.922130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117662503, states[0] = -92.001057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134274998, states[0] = -94.958009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150807114, states[0] = -94.985013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167324291, states[0] = -94.996250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184257317, states[0] = -94.938856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200886354, states[0] = -95.024258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217460158, states[0] = -95.041901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234121093, states[0] = -39.774665, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1250799540, states[0] = -94.979343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267483707, states[0] = -95.045380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284083480, states[0] = -5.032806, states[40]= 0.003369
Saving checkpoint... 
Iteration: 1300656626, states[0] = -84.432839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317442028, states[0] = -95.038552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333921420, states[0] = -95.034068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350460666, states[0] = -95.041899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367095910, states[0] = -15.649904, states[40]= 0.001373
Saving checkpoint... 
Iteration: 1383960270, states[0] = -95.041811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400526191, states[0] = 19.638359, states[40]= 0.006656
Saving checkpoint... 
Iteration: 1417126041, states[0] = -44.825758, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1434555217, states[0] = 9.523786, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1451627670, states[0] = -46.537012, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1468734008, states[0] = -94.907544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485723793, states[0] = -94.891437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502907679, states[0] = -95.170829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519917312, states[0] = -56.368565, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1536847639, states[0] = -95.259226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553880298, states[0] = -95.159094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570590622, states[0] = -27.571989, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1587438696, states[0] = -91.733668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604399851, states[0] = -95.323293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621621190, states[0] = -64.200131, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1638710813, states[0] = -50.979453, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1655556219, states[0] = -95.099167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672303046, states[0] = -41.779699, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1689208816, states[0] = -95.228900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706407118, states[0] = 25.488425, states[40]= 0.096908
Saving checkpoint... 
Iteration: 1723333545, states[0] = -84.847495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740093018, states[0] = -30.611370, states[40]= 0.000427
Saving checkpoint... 
Iteration: 1757148770, states[0] = 8.047912, states[40]= 0.005579
Saving checkpoint... 
Iteration: 1774006292, states[0] = -45.584959, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1790819440, states[0] = -61.948596, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1807627540, states[0] = -50.440228, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1824531107, states[0] = 17.837457, states[40]= 0.005790
Saving checkpoint... 
Iteration: 1841612882, states[0] = -33.029054, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1858285929, states[0] = -94.980380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875029803, states[0] = 18.547034, states[40]= 0.005992
Saving checkpoint... 
Iteration: 1891960344, states[0] = -95.046063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909022957, states[0] = 20.396628, states[40]= 0.007691
Saving checkpoint... 
Iteration: 1925972363, states[0] = -95.044994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942785529, states[0] = -94.968312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960074608, states[0] = 0.556165, states[40]= 0.004294
Saving checkpoint... 
Iteration: 1976875406, states[0] = -95.020254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994424708, states[0] = -95.034578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011378609, states[0] = -95.021147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028482890, states[0] = -95.044799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045867031, states[0] = -95.016678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063066561, states[0] = 4.639443, states[40]= 0.004660
Saving checkpoint... 
Iteration: 2080110058, states[0] = -29.071712, states[40]= 0.000507
Saving checkpoint... 
Iteration: 2097101999, states[0] = -21.417870, states[40]= 0.000875
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.922673
 - CaMKt in component CaMK (millimolar): 0.006991
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.565168
 - nass in component intracellular_ions (millimolar): 6.565228
 - ki in component intracellular_ions (millimolar): 145.412280
 - kss in component intracellular_ions (millimolar): 145.412261
 - cansr in component intracellular_ions (millimolar): 1.311698
 - cajsr in component intracellular_ions (millimolar): 1.273682
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880362
 - hs in component INa (dimensionless): 0.880357
 - j in component INa (dimensionless): 0.880329
 - hsp in component INa (dimensionless): 0.726511
 - jp in component INa (dimensionless): 0.880310
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710541
 - hLp in component INaL (dimensionless): 0.452842
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621616
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696645
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935713
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001599
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327527
 - xs1 in component IKs (dimensionless): 0.241221
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:50:48 (10540): called boinc_finish(0)

</stderr_txt>
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