𝕏

Task 55995139

Name HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359_0
Workunit 26592180
Created 3 Jul 2024, 22:31:35 UTC
Sent 3 Jul 2024, 23:47:49 UTC
Report deadline 7 Jul 2024, 9:23:49 UTC
Received 6 Jul 2024, 10:44:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228256
Run time 1 hours 30 min 17 sec
CPU time 56 min 19 sec
Validate state Valid
Credit 62.75
Device peak FLOPS 5.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.23 MB
Peak swap size 5.32 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r968294866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r968294866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.732678
     * GNaL_b in INaL: 0.005925
     * Gto_b in Ito: 0.085549
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031515
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.160626
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.336158
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9263148, states[0] = -95.003343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24833362, states[0] = -95.013707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40074757, states[0] = -0.071022, states[40]= 0.004251
Saving checkpoint... 
Iteration: 52799120, states[0] = -94.959630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66902091, states[0] = -95.004136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81948185, states[0] = -95.010274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96637120, states[0] = -55.558281, states[40]= 0.000011
Saving checkpoint... 
Iteration: 111435497, states[0] = -95.002537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126097000, states[0] = -16.051553, states[40]= 0.001329
Saving checkpoint... 
Iteration: 142089535, states[0] = -9.335275, states[40]= 0.002465
Saving checkpoint... 
Iteration: 157738975, states[0] = -94.872699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170578811, states[0] = -1.559523, states[40]= 0.004012
Saving checkpoint... 
Iteration: 184061155, states[0] = 7.246763, states[40]= 0.004811
Saving checkpoint... 
Iteration: 200164913, states[0] = -92.148075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205556328, states[0] = 9.251623, states[40]= 0.004877
Saving checkpoint... 
Iteration: 221747751, states[0] = -94.884252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236761608, states[0] = -94.901682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252561798, states[0] = 6.979516, states[40]= 0.004800
Saving checkpoint... 
Iteration: 265324803, states[0] = -94.956394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280624108, states[0] = -41.503149, states[40]= 0.000105
Saving checkpoint... 
Iteration: 290632153, states[0] = -49.789544, states[40]= 0.000029
Saving checkpoint... 
Iteration: 304981066, states[0] = -95.006794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315620053, states[0] = -37.531493, states[40]= 0.000187
Saving checkpoint... 
Iteration: 324465809, states[0] = -95.004448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335276030, states[0] = -94.917280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350006920, states[0] = 24.888744, states[40]= 0.107513
Saving checkpoint... 
Iteration: 364634211, states[0] = -51.984220, states[40]= 0.000020
Saving checkpoint... 
Iteration: 380623658, states[0] = -41.054399, states[40]= 0.000113
Saving checkpoint... 
Iteration: 396236375, states[0] = -94.867673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412669029, states[0] = -93.938241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428103359, states[0] = -21.844042, states[40]= 0.000865
Saving checkpoint... 
Iteration: 441830936, states[0] = -94.959936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456264878, states[0] = -94.905220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470861533, states[0] = -94.975409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484447327, states[0] = -95.001029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494435895, states[0] = -94.998673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508437976, states[0] = -94.999110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518585374, states[0] = -5.962809, states[40]= 0.003183
Saving checkpoint... 
Iteration: 536703771, states[0] = -94.809960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552055057, states[0] = 9.766556, states[40]= 0.004892
Saving checkpoint... 
Iteration: 564014137, states[0] = 22.191245, states[40]= 0.021473
Saving checkpoint... 
Iteration: 578900102, states[0] = -94.989409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592111254, states[0] = -29.202047, states[40]= 0.000514
Saving checkpoint... 
Iteration: 601674344, states[0] = -94.589252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616861775, states[0] = -94.975418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631796317, states[0] = -94.935661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648302873, states[0] = -94.940885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663171642, states[0] = -94.379147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677271556, states[0] = -94.912409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692803419, states[0] = -94.941276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703420207, states[0] = -94.994875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718812601, states[0] = -94.947999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735608170, states[0] = -26.323033, states[40]= 0.000653
Saving checkpoint... 
Iteration: 752093151, states[0] = -12.406288, states[40]= 0.001868
Saving checkpoint... 
Iteration: 769302667, states[0] = -94.940646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781654881, states[0] = -78.024217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790912129, states[0] = -94.992713, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r968294866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704003123300700_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r968294866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.732678
     * GNaL_b in INaL: 0.005925
     * Gto_b in Ito: 0.085549
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031515
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.160626
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.336158
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 790912129
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.992713 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 806038575, states[0] = 15.946474, states[40]= 0.005278
Saving checkpoint... 
Iteration: 819806113, states[0] = -94.943234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834486937, states[0] = -95.007245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849502528, states[0] = 40.291344, states[40]= 0.119047
Saving checkpoint... 
Iteration: 860695365, states[0] = -94.792255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876123491, states[0] = -40.888518, states[40]= 0.000115
Saving checkpoint... 
Iteration: 892403896, states[0] = -94.990332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909200090, states[0] = -94.802208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926131260, states[0] = -48.842946, states[40]= 0.000034
Saving checkpoint... 
Iteration: 938561023, states[0] = 7.311990, states[40]= 0.004813
Saving checkpoint... 
Iteration: 953041375, states[0] = 14.955233, states[40]= 0.005155
Saving checkpoint... 
Iteration: 968409191, states[0] = -94.991791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980954282, states[0] = -95.002016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992962748, states[0] = -95.003494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005081977, states[0] = -3.557736, states[40]= 0.003666
Saving checkpoint... 
Iteration: 1019356456, states[0] = -94.972784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032952706, states[0] = -95.001692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047290796, states[0] = -94.930704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061321826, states[0] = -94.953954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074867684, states[0] = -94.977615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090731490, states[0] = -94.859624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107369512, states[0] = -94.978338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121008078, states[0] = 23.913380, states[40]= 0.082972
Saving checkpoint... 
Iteration: 1135631294, states[0] = -48.878661, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1154255709, states[0] = -94.893836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170537847, states[0] = 16.198730, states[40]= 0.005317
Saving checkpoint... 
Iteration: 1182465201, states[0] = -95.003779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197358654, states[0] = -94.973662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210755875, states[0] = -94.894006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226072207, states[0] = 2.133057, states[40]= 0.004479
Saving checkpoint... 
Iteration: 1238050786, states[0] = 11.442213, states[40]= 0.004943
Saving checkpoint... 
Iteration: 1253457711, states[0] = -95.002454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265615320, states[0] = -33.020293, states[40]= 0.000339
Saving checkpoint... 
Iteration: 1275560090, states[0] = 7.706526, states[40]= 0.004828
Saving checkpoint... 
Iteration: 1289229668, states[0] = -94.856569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303622323, states[0] = -39.737417, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1317980890, states[0] = -95.006093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331171351, states[0] = -94.344342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345594366, states[0] = -13.502226, states[40]= 0.001684
Saving checkpoint... 
Iteration: 1359835642, states[0] = -94.962025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370879307, states[0] = -94.981941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387381489, states[0] = -94.982725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403196927, states[0] = -94.795252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419510992, states[0] = 22.764143, states[40]= 0.041817
Saving checkpoint... 
Iteration: 1436161600, states[0] = -88.841565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453086128, states[0] = -6.531978, states[40]= 0.003062
Saving checkpoint... 
Iteration: 1464049033, states[0] = 12.114285, states[40]= 0.004967
Saving checkpoint... 
Iteration: 1481466208, states[0] = -95.003749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496798862, states[0] = -94.937166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512539470, states[0] = -95.191170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523674384, states[0] = -95.239289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539951594, states[0] = 7.110187, states[40]= 0.005509
Saving checkpoint... 
Iteration: 1554534480, states[0] = -95.218505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564393515, states[0] = -95.153941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580797792, states[0] = -34.489185, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1597984843, states[0] = -95.141858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615148674, states[0] = -95.247505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634196620, states[0] = -33.475778, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1652110227, states[0] = 23.687425, states[40]= 0.050453
Saving checkpoint... 
Iteration: 1669382452, states[0] = -95.139409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685943455, states[0] = -95.243151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703514717, states[0] = -54.285235, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1719145715, states[0] = -94.381044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735625418, states[0] = -68.238033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1745878148, states[0] = -95.129470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761883379, states[0] = -95.281722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778807672, states[0] = -45.866956, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1796910350, states[0] = -95.195633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815654755, states[0] = -83.443857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832198932, states[0] = -94.827285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841580818, states[0] = -3.542234, states[40]= 0.003688
Saving checkpoint... 
Iteration: 1854666143, states[0] = -93.386107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870150964, states[0] = -72.906649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1887099411, states[0] = -18.468200, states[40]= 0.001086
Saving checkpoint... 
Iteration: 1902054126, states[0] = 10.073499, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1912760881, states[0] = -94.902244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928066471, states[0] = 4.870920, states[40]= 0.004695
Saving checkpoint... 
Iteration: 1944690375, states[0] = -94.781119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962885925, states[0] = -94.984464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978150597, states[0] = -71.443813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1988905211, states[0] = -94.990221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004778241, states[0] = -94.918516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018652637, states[0] = -74.441682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031465128, states[0] = -95.003235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048639843, states[0] = -58.136979, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2059525472, states[0] = 19.971812, states[40]= 0.006887
Saving checkpoint... 
Iteration: 2076783906, states[0] = -94.923766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087962287, states[0] = -95.002657, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883892
 - CaMKt in component CaMK (millimolar): 0.007046
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.608272
 - nass in component intracellular_ions (millimolar): 6.608332
 - ki in component intracellular_ions (millimolar): 145.368386
 - kss in component intracellular_ions (millimolar): 145.368367
 - cansr in component intracellular_ions (millimolar): 1.315440
 - cajsr in component intracellular_ions (millimolar): 1.277302
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879689
 - hs in component INa (dimensionless): 0.879684
 - j in component INa (dimensionless): 0.879654
 - hsp in component INa (dimensionless): 0.725242
 - jp in component INa (dimensionless): 0.879635
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709047
 - hLp in component INaL (dimensionless): 0.450279
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619694
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694279
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934791
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332053
 - xs1 in component IKs (dimensionless): 0.242998
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:53:20 (6076): called boinc_finish(0)

</stderr_txt>
]]>


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