𝕏

Task 55993421

Name HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_468_0
Workunit 26591355
Created 3 Jul 2024, 21:41:31 UTC
Sent 3 Jul 2024, 23:35:09 UTC
Report deadline 7 Jul 2024, 9:11:09 UTC
Received 6 Jul 2024, 11:42:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224565
Run time 1 hours 16 min 7 sec
CPU time 1 hours 14 min 14 sec
Validate state Valid
Credit 59.08
Device peak FLOPS 6.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.37 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_468.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_468_0_r51152198_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_468_0_r51152198_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.782806
     * GNaL_b in INaL: 0.005603
     * Gto_b in Ito: 0.086685
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.163518
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.549843
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036402
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13712721, states[0] = -94.965428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28476967, states[0] = -95.094176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42456980, states[0] = -95.073216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56282369, states[0] = -94.986375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70367611, states[0] = -95.031401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85002067, states[0] = 44.260240, states[40]= 0.091761
Saving checkpoint... 
Iteration: 99657923, states[0] = -87.668393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114365463, states[0] = -95.020746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128860538, states[0] = -95.017443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143792773, states[0] = -94.976114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158390123, states[0] = -95.026938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171818073, states[0] = -94.993563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185560970, states[0] = 6.867259, states[40]= 0.004793
Saving checkpoint... 
Iteration: 200190290, states[0] = -94.828757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214380483, states[0] = -95.022879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228494592, states[0] = -95.047326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243087130, states[0] = -8.288350, states[40]= 0.002686
Saving checkpoint... 
Iteration: 257190368, states[0] = -94.828652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270851280, states[0] = -95.010931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284003394, states[0] = 34.603034, states[40]= 0.144725
Saving checkpoint... 
Iteration: 297546404, states[0] = 12.725921, states[40]= 0.005020
Saving checkpoint... 
Iteration: 311972653, states[0] = -95.044230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325077607, states[0] = -1.494042, states[40]= 0.004019
Saving checkpoint... 
Iteration: 339700454, states[0] = -94.849654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354583327, states[0] = -5.321527, states[40]= 0.003316
Saving checkpoint... 
Iteration: 368669669, states[0] = -94.485541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382819573, states[0] = -94.993705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397594550, states[0] = -14.880729, states[40]= 0.001478
Saving checkpoint... 
Iteration: 411996630, states[0] = -95.047326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426784863, states[0] = -94.967634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440930430, states[0] = -95.036486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454635945, states[0] = -56.009620, states[40]= 0.000010
Saving checkpoint... 
Iteration: 469216456, states[0] = -94.879722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483795463, states[0] = -94.976533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498376823, states[0] = -95.021206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512394670, states[0] = -95.027140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526508405, states[0] = 23.523860, states[40]= 0.077363
Saving checkpoint... 
Iteration: 540154579, states[0] = -81.405578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554813635, states[0] = -94.989754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568023237, states[0] = 20.225325, states[40]= 0.007731
Saving checkpoint... 
Iteration: 582529218, states[0] = 18.642661, states[40]= 0.006183
Saving checkpoint... 
Iteration: 597115327, states[0] = -34.628431, states[40]= 0.000268
Saving checkpoint... 
Iteration: 611297312, states[0] = -94.977915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625423595, states[0] = -95.034822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640146722, states[0] = -69.006273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654795176, states[0] = -94.976195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669328537, states[0] = -94.998909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682957627, states[0] = -95.041599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696492199, states[0] = -95.046613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711012357, states[0] = 22.249902, states[40]= 0.031239
Saving checkpoint... 
Iteration: 725701788, states[0] = -94.852059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739179070, states[0] = -94.789240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753660010, states[0] = -89.867546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768325783, states[0] = -94.997241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782476755, states[0] = -95.044516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797089331, states[0] = -10.147679, states[40]= 0.002298
Saving checkpoint... 
Iteration: 811677022, states[0] = -94.770721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826123523, states[0] = -42.737710, states[40]= 0.000085
Saving checkpoint... 
Iteration: 840851953, states[0] = -95.010842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854962429, states[0] = -95.042289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868969924, states[0] = -95.043458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882440898, states[0] = -95.038393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896806267, states[0] = -94.984447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910856428, states[0] = -95.012805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925457324, states[0] = -95.041394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940111478, states[0] = -30.932993, states[40]= 0.000418
Saving checkpoint... 
Iteration: 954647964, states[0] = -70.742904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968755707, states[0] = -94.937086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982780017, states[0] = -94.962864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996936248, states[0] = -95.037375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011043432, states[0] = 13.839424, states[40]= 0.005098
Saving checkpoint... 
Iteration: 1025613686, states[0] = -33.047837, states[40]= 0.000327
Saving checkpoint... 
Iteration: 1039817710, states[0] = -94.992106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054334162, states[0] = -95.001812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068887529, states[0] = -95.024528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083512044, states[0] = 22.310237, states[40]= 0.033430
Saving checkpoint... 
Iteration: 1097183861, states[0] = -94.811317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111253637, states[0] = -94.934487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125090765, states[0] = -11.411016, states[40]= 0.002050
Saving checkpoint... 
Iteration: 1138664027, states[0] = -93.105347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153200875, states[0] = -94.849971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167277494, states[0] = -94.960360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181864882, states[0] = -95.016200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195943830, states[0] = -95.038769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210025878, states[0] = 19.569494, states[40]= 0.006855
Saving checkpoint... 
Iteration: 1224121491, states[0] = -40.681684, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1237814936, states[0] = -94.990182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251938457, states[0] = -95.037668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266591251, states[0] = -11.846680, states[40]= 0.001969
Saving checkpoint... 
Iteration: 1280697985, states[0] = -94.844062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294682339, states[0] = -94.805841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309217804, states[0] = -94.881550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323865721, states[0] = -95.016448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338437953, states[0] = -95.037510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352507464, states[0] = 24.197443, states[40]= 0.095776
Saving checkpoint... 
Iteration: 1367105919, states[0] = -25.643292, states[40]= 0.000668
Saving checkpoint... 
Iteration: 1380740509, states[0] = -94.917112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394284078, states[0] = -94.966319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408885722, states[0] = -95.023717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423565003, states[0] = 5.085794, states[40]= 0.004703
Saving checkpoint... 
Iteration: 1438132121, states[0] = -51.811204, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1452648196, states[0] = -71.075345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467187282, states[0] = -94.820598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481821162, states[0] = -94.993996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495938738, states[0] = -95.037571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509943528, states[0] = 11.405183, states[40]= 0.005816
Saving checkpoint... 
Iteration: 1523539573, states[0] = -90.892821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537485920, states[0] = -95.295042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551962070, states[0] = 0.226403, states[40]= 0.004801
Saving checkpoint... 
Iteration: 1566565195, states[0] = -95.292017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581184172, states[0] = -95.177351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595344417, states[0] = -95.276451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609879512, states[0] = -16.103362, states[40]= 0.001483
Saving checkpoint... 
Iteration: 1624286733, states[0] = -24.080777, states[40]= 0.000756
Saving checkpoint... 
Iteration: 1638470196, states[0] = -95.149152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652983710, states[0] = -95.315523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667462616, states[0] = -0.530357, states[40]= 0.004695
Saving checkpoint... 
Iteration: 1681519183, states[0] = 20.811721, states[40]= 0.011917
Saving checkpoint... 
Iteration: 1696091536, states[0] = -95.198380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710092782, states[0] = -30.781085, states[40]= 0.000417
Saving checkpoint... 
Iteration: 1724670286, states[0] = -95.305298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738844562, states[0] = 10.054077, states[40]= 0.005789
Saving checkpoint... 
Iteration: 1752944509, states[0] = 10.081021, states[40]= 0.005791
Saving checkpoint... 
Iteration: 1767107398, states[0] = -47.333786, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1780755241, states[0] = -95.291373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794368483, states[0] = -5.121290, states[40]= 0.003788
Saving checkpoint... 
Iteration: 1808936148, states[0] = -95.087814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823524851, states[0] = 19.466520, states[40]= 0.007043
Saving checkpoint... 
Iteration: 1837636698, states[0] = -58.711111, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1851760813, states[0] = -94.958083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866329573, states[0] = -95.008732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880440741, states[0] = -95.044253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894554983, states[0] = 9.294088, states[40]= 0.004884
Saving checkpoint... 
Iteration: 1908713368, states[0] = -94.876168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921868936, states[0] = -95.019231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936435883, states[0] = -95.037913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950549215, states[0] = 11.638149, states[40]= 0.004965
Saving checkpoint... 
Iteration: 1965124023, states[0] = -43.285664, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1979243055, states[0] = -94.920562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992925651, states[0] = -95.034618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006985041, states[0] = -95.044978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021493711, states[0] = -95.046007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034643978, states[0] = -65.413068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2049216780, states[0] = -94.879277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063825908, states[0] = -94.996468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077843862, states[0] = -95.006166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092449260, states[0] = -95.039184, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.922478
 - CaMKt in component CaMK (millimolar): 0.006939
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.567631
 - nass in component intracellular_ions (millimolar): 6.567690
 - ki in component intracellular_ions (millimolar): 145.410616
 - kss in component intracellular_ions (millimolar): 145.410596
 - cansr in component intracellular_ions (millimolar): 1.308997
 - cajsr in component intracellular_ions (millimolar): 1.271108
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880358
 - hs in component INa (dimensionless): 0.880354
 - j in component INa (dimensionless): 0.880325
 - hsp in component INa (dimensionless): 0.726505
 - jp in component INa (dimensionless): 0.880306
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710609
 - hLp in component INaL (dimensionless): 0.453048
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622083
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697223
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329517
 - xs1 in component IKs (dimensionless): 0.239836
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:42:21 (29917): called boinc_finish(0)

</stderr_txt>
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