𝕏

Task 55993417

Name HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_467_0
Workunit 26591353
Created 3 Jul 2024, 21:41:31 UTC
Sent 3 Jul 2024, 23:35:09 UTC
Report deadline 7 Jul 2024, 9:11:09 UTC
Received 6 Jul 2024, 14:21:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224565
Run time 1 hours 19 min 12 sec
CPU time 1 hours 16 min 16 sec
Validate state Valid
Credit 59.26
Device peak FLOPS 6.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.37 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_467.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_467_0_r1314106428_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234110836707_ORdGradInc_k_26-Pueyo_APDR-conf_467_0_r1314106428_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.835506
     * GNaL_b in INaL: 0.005913
     * Gto_b in Ito: 0.086777
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031575
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.166227
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.412405
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037296
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13810077, states[0] = -95.060366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27966396, states[0] = -95.079972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41310326, states[0] = -95.007624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55044777, states[0] = 13.326283, states[40]= 0.005046
Saving checkpoint... 
Iteration: 68800001, states[0] = -94.981541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83006439, states[0] = 25.300245, states[40]= 0.118669
Saving checkpoint... 
Iteration: 96943723, states[0] = -95.032109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111040093, states[0] = 15.295975, states[40]= 0.005205
Saving checkpoint... 
Iteration: 124266784, states[0] = -94.940332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136144830, states[0] = -64.589247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 149452629, states[0] = -95.029031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163583186, states[0] = -4.424511, states[40]= 0.003484
Saving checkpoint... 
Iteration: 177355517, states[0] = -95.000405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188650389, states[0] = -71.981482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200883334, states[0] = -95.010843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214632172, states[0] = -50.080423, states[40]= 0.000027
Saving checkpoint... 
Iteration: 227884920, states[0] = -95.011207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241613562, states[0] = -31.477618, states[40]= 0.000399
Saving checkpoint... 
Iteration: 255323363, states[0] = -94.983308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269604503, states[0] = -22.975908, states[40]= 0.000800
Saving checkpoint... 
Iteration: 283800763, states[0] = -94.968062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297927674, states[0] = -95.022753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311698511, states[0] = -94.834258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325485955, states[0] = -95.032730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338789189, states[0] = -94.958786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352506740, states[0] = 24.971847, states[40]= 0.111407
Saving checkpoint... 
Iteration: 365896423, states[0] = -95.014620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380250316, states[0] = -94.918450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393788847, states[0] = -94.958458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408026977, states[0] = 19.498415, states[40]= 0.006566
Saving checkpoint... 
Iteration: 422102478, states[0] = -21.079539, states[40]= 0.000898
Saving checkpoint... 
Iteration: 436378896, states[0] = -95.008896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450184267, states[0] = -94.800836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464431449, states[0] = -95.023458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478211356, states[0] = -94.858694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492430203, states[0] = -95.023171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506184934, states[0] = -94.803006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520805775, states[0] = -94.971560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534888159, states[0] = -95.011950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549301388, states[0] = -94.968338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563599992, states[0] = -18.751908, states[40]= 0.001055
Saving checkpoint... 
Iteration: 577892691, states[0] = -95.013352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591537302, states[0] = 16.322706, states[40]= 0.005351
Saving checkpoint... 
Iteration: 604883064, states[0] = -95.010225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618634379, states[0] = -52.451158, states[40]= 0.000019
Saving checkpoint... 
Iteration: 632658794, states[0] = -86.034874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645768223, states[0] = -94.938847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659985358, states[0] = -95.032434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673362918, states[0] = -95.002682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686613425, states[0] = -31.342928, states[40]= 0.000405
Saving checkpoint... 
Iteration: 699824901, states[0] = -94.983888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713573853, states[0] = 1.260650, states[40]= 0.004370
Saving checkpoint... 
Iteration: 726370768, states[0] = -95.005742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738640496, states[0] = -59.261984, states[40]= 0.000006
Saving checkpoint... 
Iteration: 752464220, states[0] = -95.029344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765672664, states[0] = -94.605133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778980029, states[0] = -95.031651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793389821, states[0] = -95.012318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807116162, states[0] = -33.937358, states[40]= 0.000297
Saving checkpoint... 
Iteration: 819944819, states[0] = -95.025934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834264777, states[0] = -94.935058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848518736, states[0] = 21.341309, states[40]= 0.010975
Saving checkpoint... 
Iteration: 862165780, states[0] = -93.264505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875818720, states[0] = -94.980010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889561440, states[0] = 7.103571, states[40]= 0.004787
Saving checkpoint... 
Iteration: 903305882, states[0] = -94.971394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917077022, states[0] = -0.489971, states[40]= 0.004152
Saving checkpoint... 
Iteration: 931264960, states[0] = -94.935195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945506347, states[0] = 25.477643, states[40]= 0.120361
Saving checkpoint... 
Iteration: 959723448, states[0] = -94.879314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972105620, states[0] = -24.017825, states[40]= 0.000751
Saving checkpoint... 
Iteration: 986322821, states[0] = -94.982465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000123438, states[0] = -41.006609, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1014345180, states[0] = -94.994559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027633711, states[0] = -51.725611, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1041371255, states[0] = -95.005728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054178484, states[0] = -94.765417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067504683, states[0] = 29.034146, states[40]= 0.151614
Saving checkpoint... 
Iteration: 1081683283, states[0] = -94.796802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094478649, states[0] = -95.031262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108618150, states[0] = -35.837868, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1122682729, states[0] = -94.794486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135949345, states[0] = -95.026576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149619060, states[0] = -36.714091, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1162976729, states[0] = -95.030951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176712358, states[0] = -94.860066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191004344, states[0] = 30.175288, states[40]= 0.153879
Saving checkpoint... 
Iteration: 1205280803, states[0] = -94.950840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219445485, states[0] = -95.025808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233189582, states[0] = -94.814826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246449675, states[0] = -95.026566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260223149, states[0] = -94.878632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273986539, states[0] = -95.032198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287770655, states[0] = -94.940953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300805272, states[0] = -94.970705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314654308, states[0] = -78.234410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328074609, states[0] = 0.856028, states[40]= 0.004324
Saving checkpoint... 
Iteration: 1342177943, states[0] = -94.758936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355635855, states[0] = -54.063874, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1369353331, states[0] = -94.998135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383582055, states[0] = -3.617856, states[40]= 0.003639
Saving checkpoint... 
Iteration: 1397830922, states[0] = -94.986901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411540720, states[0] = 15.131359, states[40]= 0.005177
Saving checkpoint... 
Iteration: 1425297180, states[0] = -94.964574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439556228, states[0] = 9.258391, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1453782871, states[0] = -94.952564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467560329, states[0] = 7.573651, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1480925526, states[0] = -95.021506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495085489, states[0] = -6.057478, states[40]= 0.003149
Saving checkpoint... 
Iteration: 1508820694, states[0] = -58.167369, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1522947827, states[0] = -94.553527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536590375, states[0] = -95.279827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550176860, states[0] = -11.615217, states[40]= 0.002267
Saving checkpoint... 
Iteration: 1563881539, states[0] = -95.286589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577576757, states[0] = -95.142769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591710579, states[0] = -95.211802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605449436, states[0] = -94.929061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619650997, states[0] = -95.267296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633423351, states[0] = -95.234089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647098803, states[0] = -35.989482, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1660873442, states[0] = -8.830162, states[40]= 0.002900
Saving checkpoint... 
Iteration: 1674822766, states[0] = -95.233940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688878549, states[0] = -95.152764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703012833, states[0] = -95.219068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716168773, states[0] = -95.129116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729411700, states[0] = -95.217284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743012414, states[0] = 22.839538, states[40]= 0.032225
Saving checkpoint... 
Iteration: 1756215740, states[0] = 21.937529, states[40]= 0.018023
Saving checkpoint... 
Iteration: 1767133955, states[0] = -83.726512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780823332, states[0] = 19.641531, states[40]= 0.008854
Saving checkpoint... 
Iteration: 1793773679, states[0] = -9.077132, states[40]= 0.002842
Saving checkpoint... 
Iteration: 1807181971, states[0] = -94.838743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820786220, states[0] = -94.991613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834848640, states[0] = -95.020051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848622131, states[0] = -40.792088, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1862810604, states[0] = -94.984680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877008274, states[0] = 23.623940, states[40]= 0.079574
Saving checkpoint... 
Iteration: 1890692735, states[0] = -94.826005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904466498, states[0] = -95.031969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918226017, states[0] = -94.884892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932420737, states[0] = -95.021385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945879921, states[0] = -95.009138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960088921, states[0] = -8.795043, states[40]= 0.002567
Saving checkpoint... 
Iteration: 1973856954, states[0] = -94.999685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987935289, states[0] = -95.023507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000386649, states[0] = -95.010656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013797716, states[0] = -94.964682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027864450, states[0] = -95.002471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040806738, states[0] = -94.971280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054563296, states[0] = 6.303019, states[40]= 0.004752
Saving checkpoint... 
Iteration: 2067984464, states[0] = -95.031397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082157993, states[0] = -84.693080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096244583, states[0] = -94.909890, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909125
 - CaMKt in component CaMK (millimolar): 0.006959
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.561988
 - nass in component intracellular_ions (millimolar): 6.562048
 - ki in component intracellular_ions (millimolar): 145.416375
 - kss in component intracellular_ions (millimolar): 145.416356
 - cansr in component intracellular_ions (millimolar): 1.308542
 - cajsr in component intracellular_ions (millimolar): 1.270461
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880127
 - hs in component INa (dimensionless): 0.880122
 - j in component INa (dimensionless): 0.880094
 - hsp in component INa (dimensionless): 0.726069
 - jp in component INa (dimensionless): 0.880076
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709919
 - hLp in component INaL (dimensionless): 0.451649
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620313
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695067
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935026
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001587
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331584
 - xs1 in component IKs (dimensionless): 0.242816
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:20:46 (30172): called boinc_finish(0)

</stderr_txt>
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