𝕏

Task 55992361

Name HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_755_1
Workunit 26590825
Created 3 Jul 2024, 21:40:54 UTC
Sent 3 Jul 2024, 23:22:27 UTC
Report deadline 7 Jul 2024, 8:58:27 UTC
Received 4 Jul 2024, 7:26:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240196
Run time 1 hours 34 min 19 sec
CPU time 1 hours 34 min 19 sec
Validate state Valid
Credit 58.53
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.00 MB
Peak swap size 1.59 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_755.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_755_1_r1759719817_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_755_1_r1759719817_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.618961
     * GNaL_b in INaL: 0.005431
     * Gto_b in Ito: 0.086075
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031863
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.162135
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.660502
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034062
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9321620, states[0] = -95.074565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21977114, states[0] = -95.086072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34410949, states[0] = -95.053033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47027072, states[0] = 18.979256, states[40]= 0.006512
Saving checkpoint... 
Iteration: 59678985, states[0] = -94.791014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72320362, states[0] = -94.988270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85187479, states[0] = -94.809387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97626489, states[0] = -46.704315, states[40]= 0.000046
Saving checkpoint... 
Iteration: 110114046, states[0] = -34.072487, states[40]= 0.000288
Saving checkpoint... 
Iteration: 122495575, states[0] = -95.032762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134756866, states[0] = -94.921718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147166672, states[0] = -94.068619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159287371, states[0] = -94.952228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170292306, states[0] = -94.956201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182842088, states[0] = -94.988884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195344142, states[0] = -94.989773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208036759, states[0] = 16.220307, states[40]= 0.005399
Saving checkpoint... 
Iteration: 220605440, states[0] = -25.583809, states[40]= 0.000669
Saving checkpoint... 
Iteration: 233032752, states[0] = 17.560242, states[40]= 0.005721
Saving checkpoint... 
Iteration: 245482399, states[0] = -95.028297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257892232, states[0] = -95.008842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270203386, states[0] = -94.834925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282385277, states[0] = -95.006510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294634559, states[0] = -54.983528, states[40]= 0.000012
Saving checkpoint... 
Iteration: 306924112, states[0] = -95.017552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319344417, states[0] = -94.989510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331638421, states[0] = -59.297206, states[40]= 0.000006
Saving checkpoint... 
Iteration: 343737329, states[0] = -94.893583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356022508, states[0] = 20.415020, states[40]= 0.008015
Saving checkpoint... 
Iteration: 368338529, states[0] = -94.986434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380555698, states[0] = 9.033498, states[40]= 0.004876
Saving checkpoint... 
Iteration: 392658268, states[0] = -87.943478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404847887, states[0] = -94.991157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417039445, states[0] = 15.277667, states[40]= 0.005249
Saving checkpoint... 
Iteration: 429350240, states[0] = -94.992269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441576729, states[0] = -1.109777, states[40]= 0.004085
Saving checkpoint... 
Iteration: 453917542, states[0] = -95.015842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466156932, states[0] = -85.917692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478524730, states[0] = 19.880758, states[40]= 0.007147
Saving checkpoint... 
Iteration: 490820837, states[0] = -94.976107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503190511, states[0] = -94.807709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511968070, states[0] = -95.025944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524343755, states[0] = -94.989036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536782347, states[0] = -94.946489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549018619, states[0] = 21.220629, states[40]= 0.011074
Saving checkpoint... 
Iteration: 561986226, states[0] = -95.028533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574671808, states[0] = -94.621520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587214523, states[0] = -94.855935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599674174, states[0] = -94.702878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612293353, states[0] = -94.956098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624901616, states[0] = -95.011414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637521839, states[0] = 20.565530, states[40]= 0.008365
Saving checkpoint... 
Iteration: 650086061, states[0] = -7.652437, states[40]= 0.002828
Saving checkpoint... 
Iteration: 662382522, states[0] = -95.005291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674616298, states[0] = -36.015441, states[40]= 0.000223
Saving checkpoint... 
Iteration: 687029278, states[0] = 18.633602, states[40]= 0.006151
Saving checkpoint... 
Iteration: 699226597, states[0] = -94.876718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711506046, states[0] = 25.910685, states[40]= 0.127459
Saving checkpoint... 
Iteration: 720294477, states[0] = -94.956955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732855704, states[0] = -94.994597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745280209, states[0] = -94.944350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757579378, states[0] = -2.770224, states[40]= 0.003814
Saving checkpoint... 
Iteration: 769812482, states[0] = -94.970434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782186183, states[0] = -94.797033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794554054, states[0] = 9.702488, states[40]= 0.004897
Saving checkpoint... 
Iteration: 806836853, states[0] = -94.985253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819176617, states[0] = -94.745338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831525045, states[0] = 19.800885, states[40]= 0.007051
Saving checkpoint... 
Iteration: 843561770, states[0] = 6.459658, states[40]= 0.004780
Saving checkpoint... 
Iteration: 855800842, states[0] = -94.961925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868146597, states[0] = -69.365384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880472189, states[0] = -95.026342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892669776, states[0] = -94.488414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905125230, states[0] = -44.988779, states[40]= 0.000060
Saving checkpoint... 
Iteration: 917524627, states[0] = 19.906764, states[40]= 0.007179
Saving checkpoint... 
Iteration: 929820713, states[0] = -94.975746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938330326, states[0] = -94.981534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950659205, states[0] = -89.199449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962891262, states[0] = -95.008025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975195113, states[0] = -94.817443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987477332, states[0] = -95.027032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999792426, states[0] = -94.955075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012153848, states[0] = -80.686559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024461505, states[0] = -95.024552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036706677, states[0] = -94.840866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049066097, states[0] = 4.494691, states[40]= 0.004672
Saving checkpoint... 
Iteration: 1061429918, states[0] = -95.018392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073835819, states[0] = -94.984521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086126224, states[0] = -46.025894, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1098269995, states[0] = -94.933917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110523825, states[0] = 20.104839, states[40]= 0.007455
Saving checkpoint... 
Iteration: 1119176135, states[0] = -94.738793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131453009, states[0] = -95.023006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143837849, states[0] = -94.985571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156200021, states[0] = -94.827529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168541561, states[0] = 14.510437, states[40]= 0.005159
Saving checkpoint... 
Iteration: 1180883717, states[0] = -95.005372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193207177, states[0] = -94.841734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204786403, states[0] = -94.949743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217357506, states[0] = -94.995089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229922854, states[0] = -95.016647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238578002, states[0] = -1.890346, states[40]= 0.003963
Saving checkpoint... 
Iteration: 1250865473, states[0] = -94.998460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263257886, states[0] = -94.920243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275453626, states[0] = -95.023025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284053226, states[0] = 10.035717, states[40]= 0.004908
Saving checkpoint... 
Iteration: 1296172638, states[0] = -94.656095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308710370, states[0] = -94.847763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321304699, states[0] = -94.964536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333893727, states[0] = -95.008570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346844623, states[0] = -94.988943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359550154, states[0] = 11.251850, states[40]= 0.004950
Saving checkpoint... 
Iteration: 1372445707, states[0] = -95.021485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384774683, states[0] = -94.938549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397067588, states[0] = 3.784690, states[40]= 0.004623
Saving checkpoint... 
Iteration: 1409304817, states[0] = -94.964566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421568657, states[0] = 3.263337, states[40]= 0.004583
Saving checkpoint... 
Iteration: 1434221425, states[0] = -94.867591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446698749, states[0] = -94.824733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459138063, states[0] = -58.888849, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1471634779, states[0] = -55.223290, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1484052091, states[0] = 10.488584, states[40]= 0.004923
Saving checkpoint... 
Iteration: 1496141921, states[0] = -63.385323, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1508468872, states[0] = -3.582817, states[40]= 0.004048
Saving checkpoint... 
Iteration: 1520580993, states[0] = -95.120153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532884237, states[0] = -95.138669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541696727, states[0] = -95.289727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553983278, states[0] = -95.286741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566261720, states[0] = -95.272859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578440569, states[0] = -93.227563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590789219, states[0] = -95.172091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603108724, states[0] = -95.210727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615305925, states[0] = -45.863536, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1627920467, states[0] = -64.016604, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1640836206, states[0] = -89.594602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653336502, states[0] = 14.006071, states[40]= 0.006294
Saving checkpoint... 
Iteration: 1662868698, states[0] = -95.288037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674953968, states[0] = 4.909515, states[40]= 0.005353
Saving checkpoint... 
Iteration: 1687416077, states[0] = -95.225410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703362372, states[0] = -95.282525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715635684, states[0] = -95.253268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728002764, states[0] = 39.559662, states[40]= 0.102373
Saving checkpoint... 
Iteration: 1740270431, states[0] = -95.289857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752572817, states[0] = -95.291897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764991422, states[0] = -29.608073, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1777231377, states[0] = 16.307964, states[40]= 0.006839
Saving checkpoint... 
Iteration: 1789546925, states[0] = 8.804525, states[40]= 0.005677
Saving checkpoint... 
Iteration: 1801754824, states[0] = -94.979215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813975627, states[0] = -95.072005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826564045, states[0] = 4.704811, states[40]= 0.004718
Saving checkpoint... 
Iteration: 1839154704, states[0] = -85.024335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851783223, states[0] = -94.962210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860498572, states[0] = -95.041273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872809236, states[0] = -94.975883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885077446, states[0] = -1.736405, states[40]= 0.003993
Saving checkpoint... 
Iteration: 1897252264, states[0] = -94.917064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909531440, states[0] = 17.942719, states[40]= 0.005861
Saving checkpoint... 
Iteration: 1921666681, states[0] = -94.079747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933920486, states[0] = -95.016967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946222045, states[0] = -94.869267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958259522, states[0] = -94.922371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970874391, states[0] = -95.001922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983524386, states[0] = 19.963804, states[40]= 0.007257
Saving checkpoint... 
Iteration: 1992684981, states[0] = -94.793115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005202657, states[0] = -94.832429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017675125, states[0] = -94.722146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030063658, states[0] = 5.616651, states[40]= 0.004738
Saving checkpoint... 
Iteration: 2042444731, states[0] = -95.020866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054831736, states[0] = -94.981604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067161002, states[0] = -91.161083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079504636, states[0] = 29.155741, states[40]= 0.153173
Saving checkpoint... 
Iteration: 2091901047, states[0] = -95.010262, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.905083
 - CaMKt in component CaMK (millimolar): 0.006956
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591589
 - nass in component intracellular_ions (millimolar): 6.591649
 - ki in component intracellular_ions (millimolar): 145.386196
 - kss in component intracellular_ions (millimolar): 145.386177
 - cansr in component intracellular_ions (millimolar): 1.310667
 - cajsr in component intracellular_ions (millimolar): 1.272806
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880057
 - hs in component INa (dimensionless): 0.880052
 - j in component INa (dimensionless): 0.880023
 - hsp in component INa (dimensionless): 0.725936
 - jp in component INa (dimensionless): 0.880004
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710220
 - hLp in component INaL (dimensionless): 0.452741
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622398
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697566
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936579
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001595
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328389
 - xs1 in component IKs (dimensionless): 0.239182
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:36:01 (33200): called boinc_finish(0)

</stderr_txt>
]]>