𝕏

Task 55992345

Name HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_352_1
Workunit 26590817
Created 3 Jul 2024, 21:40:54 UTC
Sent 3 Jul 2024, 23:22:26 UTC
Report deadline 7 Jul 2024, 8:58:26 UTC
Received 4 Jul 2024, 3:01:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240196
Run time 1 hours 34 min
CPU time 1 hours 34 min
Validate state Valid
Credit 62.06
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.00 MB
Peak swap size 1.56 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_352.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_352_1_r112710232_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_352_1_r112710232_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.286084
     * GNaL_b in INaL: 0.005450
     * Gto_b in Ito: 0.086778
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031887
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.161621
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.451199
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033044
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12849405, states[0] = -95.043919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25301303, states[0] = -94.982418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37697084, states[0] = -94.821756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50292566, states[0] = -94.944741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62762102, states[0] = -94.906753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75184505, states[0] = -94.766269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91252771, states[0] = -94.885782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103618913, states[0] = -38.473297, states[40]= 0.000161
Saving checkpoint... 
Iteration: 116707449, states[0] = -94.809053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129028866, states[0] = 18.742646, states[40]= 0.006121
Saving checkpoint... 
Iteration: 141420861, states[0] = -94.984055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153863148, states[0] = -94.964628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166278090, states[0] = -94.907856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178663641, states[0] = -92.572461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191057325, states[0] = 8.433951, states[40]= 0.004844
Saving checkpoint... 
Iteration: 203519532, states[0] = 21.021218, states[40]= 0.009878
Saving checkpoint... 
Iteration: 215797842, states[0] = -94.924862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227147659, states[0] = -69.943569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239404008, states[0] = -94.977975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251795488, states[0] = -94.922799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264059547, states[0] = 7.506352, states[40]= 0.004813
Saving checkpoint... 
Iteration: 276195666, states[0] = -94.781482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288491465, states[0] = -94.995159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301310571, states[0] = -94.934276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313957623, states[0] = -94.990052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326598687, states[0] = -18.862060, states[40]= 0.001050
Saving checkpoint... 
Iteration: 339257804, states[0] = -94.884745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351730004, states[0] = -94.845747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364045035, states[0] = 13.272713, states[40]= 0.005019
Saving checkpoint... 
Iteration: 376365842, states[0] = -94.964507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388739595, states[0] = -94.860420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401126137, states[0] = -45.445874, states[40]= 0.000057
Saving checkpoint... 
Iteration: 413451403, states[0] = -94.988853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425763223, states[0] = -94.891079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434370357, states[0] = -94.966300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446655486, states[0] = -82.271354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459068341, states[0] = 3.519657, states[40]= 0.004599
Saving checkpoint... 
Iteration: 471410581, states[0] = -94.979575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483829105, states[0] = -94.946160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496224302, states[0] = -94.836234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508559023, states[0] = 7.729608, states[40]= 0.004821
Saving checkpoint... 
Iteration: 521010276, states[0] = 22.662494, states[40]= 0.049226
Saving checkpoint... 
Iteration: 533428979, states[0] = -94.984134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545646393, states[0] = -68.224682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557977530, states[0] = -94.993061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570241539, states[0] = -94.863109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582539469, states[0] = 15.312027, states[40]= 0.005202
Saving checkpoint... 
Iteration: 594984599, states[0] = -94.994030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607358941, states[0] = -94.961391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620043822, states[0] = 13.725616, states[40]= 0.005050
Saving checkpoint... 
Iteration: 632740733, states[0] = -94.861907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645273267, states[0] = -94.901885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657776659, states[0] = -94.905329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670421059, states[0] = -94.982158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682972412, states[0] = -94.992215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695664380, states[0] = -92.955025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708343952, states[0] = -94.954181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720826383, states[0] = -94.944370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733372240, states[0] = -94.966840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746101018, states[0] = -21.073697, states[40]= 0.000898
Saving checkpoint... 
Iteration: 754535580, states[0] = 16.660258, states[40]= 0.005421
Saving checkpoint... 
Iteration: 766866235, states[0] = -94.964405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779276535, states[0] = -94.905123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791671102, states[0] = -94.493626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803998842, states[0] = -94.995698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816465226, states[0] = -94.990992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829139708, states[0] = -60.105438, states[40]= 0.000005
Saving checkpoint... 
Iteration: 841724793, states[0] = -94.836831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854008900, states[0] = 23.158823, states[40]= 0.068357
Saving checkpoint... 
Iteration: 866286001, states[0] = -94.914099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878513055, states[0] = 22.088438, states[40]= 0.026394
Saving checkpoint... 
Iteration: 887302792, states[0] = -94.928124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899813338, states[0] = -94.935796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912652285, states[0] = -76.867357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925292240, states[0] = -94.919556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937703846, states[0] = -94.797960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949993161, states[0] = -94.994908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962332700, states[0] = -94.947927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974675744, states[0] = -94.682315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987114061, states[0] = -33.473445, states[40]= 0.000315
Saving checkpoint... 
Iteration: 999456987, states[0] = -94.989470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011802132, states[0] = -94.927532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024194336, states[0] = -94.778076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036614977, states[0] = -34.353506, states[40]= 0.000282
Saving checkpoint... 
Iteration: 1049300556, states[0] = -94.926279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061869591, states[0] = -94.965572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074476038, states[0] = -94.992496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087009106, states[0] = 23.068003, states[40]= 0.065071
Saving checkpoint... 
Iteration: 1099640901, states[0] = -61.475258, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1111990321, states[0] = -94.994439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124300799, states[0] = -94.926419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136603064, states[0] = -23.013397, states[40]= 0.000796
Saving checkpoint... 
Iteration: 1148923373, states[0] = -94.982402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161193890, states[0] = -94.777012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173780934, states[0] = -94.909164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186308475, states[0] = -94.932162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198729832, states[0] = -94.844895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210918274, states[0] = -94.981099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223131136, states[0] = -50.706934, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1235572287, states[0] = 1.515407, states[40]= 0.004418
Saving checkpoint... 
Iteration: 1247938545, states[0] = -94.985752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260214839, states[0] = -94.818959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272552265, states[0] = 10.489874, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1284849969, states[0] = -94.956785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296949475, states[0] = -94.987897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309448405, states[0] = -94.987686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321929360, states[0] = -94.983692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334478431, states[0] = -94.992671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346920370, states[0] = -94.981533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359578332, states[0] = -1.962413, states[40]= 0.003952
Saving checkpoint... 
Iteration: 1372083970, states[0] = -5.839907, states[40]= 0.003216
Saving checkpoint... 
Iteration: 1384549843, states[0] = 11.439014, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1396923757, states[0] = -94.982328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409355516, states[0] = -94.959310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421970429, states[0] = -94.991414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434522787, states[0] = 20.343534, states[40]= 0.007734
Saving checkpoint... 
Iteration: 1443172274, states[0] = -94.566814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452886905, states[0] = -94.971701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465273829, states[0] = -94.901913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477656527, states[0] = -84.037087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490047216, states[0] = 12.448930, states[40]= 0.004975
Saving checkpoint... 
Iteration: 1502398501, states[0] = -95.216202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514586114, states[0] = -95.090738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526865255, states[0] = -95.050531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539235189, states[0] = -95.197350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551554146, states[0] = -95.226610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563945140, states[0] = 9.961073, states[40]= 0.005743
Saving checkpoint... 
Iteration: 1576420917, states[0] = -95.192516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588717699, states[0] = -95.189723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601520278, states[0] = -63.002024, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1614061325, states[0] = 0.444159, states[40]= 0.004849
Saving checkpoint... 
Iteration: 1626320233, states[0] = 20.504204, states[40]= 0.010608
Saving checkpoint... 
Iteration: 1638507264, states[0] = -95.175844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650804631, states[0] = -95.171400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663468636, states[0] = -95.254953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676235885, states[0] = -88.341466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688598951, states[0] = -95.161116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700824973, states[0] = -69.803788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1713174502, states[0] = -95.107189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725482697, states[0] = -95.126833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737760150, states[0] = -95.065417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750146771, states[0] = -95.233111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762392505, states[0] = -95.148277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771039674, states[0] = -92.482722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783314907, states[0] = -56.365761, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1795639524, states[0] = -92.373170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808010218, states[0] = 22.381329, states[40]= 0.049636
Saving checkpoint... 
Iteration: 1820354695, states[0] = -94.997228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832717966, states[0] = -94.851867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845056970, states[0] = 8.232717, states[40]= 0.004850
Saving checkpoint... 
Iteration: 1853757117, states[0] = -94.897743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866008585, states[0] = 23.254530, states[40]= 0.073748
Saving checkpoint... 
Iteration: 1878190084, states[0] = -94.775160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890423207, states[0] = -94.986748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902654507, states[0] = -81.017850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914958634, states[0] = -94.991479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927241691, states[0] = -94.864055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940017945, states[0] = 21.302789, states[40]= 0.011731
Saving checkpoint... 
Iteration: 1952520156, states[0] = 20.895674, states[40]= 0.009327
Saving checkpoint... 
Iteration: 1960959633, states[0] = -94.989844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973090263, states[0] = -11.049119, states[40]= 0.002125
Saving checkpoint... 
Iteration: 1985411747, states[0] = -94.979115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997761775, states[0] = -94.888497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010099483, states[0] = -19.624212, states[40]= 0.000992
Saving checkpoint... 
Iteration: 2022264438, states[0] = -94.891431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034522711, states[0] = 20.360236, states[40]= 0.007768
Saving checkpoint... 
Iteration: 2046805156, states[0] = -94.929126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059107305, states[0] = -27.034839, states[40]= 0.000608
Saving checkpoint... 
Iteration: 2071369637, states[0] = -94.964876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083591477, states[0] = -12.117431, states[40]= 0.001924
Saving checkpoint... 
Iteration: 2096054659, states[0] = 9.532709, states[40]= 0.004875
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.870792
 - CaMKt in component CaMK (millimolar): 0.007048
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.585244
 - nass in component intracellular_ions (millimolar): 6.585304
 - ki in component intracellular_ions (millimolar): 145.390941
 - kss in component intracellular_ions (millimolar): 145.390922
 - cansr in component intracellular_ions (millimolar): 1.316758
 - cajsr in component intracellular_ions (millimolar): 1.278759
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879461
 - hs in component INa (dimensionless): 0.879456
 - j in component INa (dimensionless): 0.879427
 - hsp in component INa (dimensionless): 0.724813
 - jp in component INa (dimensionless): 0.879407
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709161
 - hLp in component INaL (dimensionless): 0.451258
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621609
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696624
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936397
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001619
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327714
 - xs1 in component IKs (dimensionless): 0.239748
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:00:48 (29472): called boinc_finish(0)

</stderr_txt>
]]>


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