𝕏

Task 55992337

Name HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551_1
Workunit 26590813
Created 3 Jul 2024, 21:40:54 UTC
Sent 3 Jul 2024, 23:21:38 UTC
Report deadline 7 Jul 2024, 8:57:38 UTC
Received 5 Jul 2024, 23:45:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228256
Run time 1 hours 29 min 13 sec
CPU time 56 min 20 sec
Validate state Valid
Credit 58.55
Device peak FLOPS 5.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 5.30 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551_1_r848482053_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551_1_r848482053_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.265350
     * GNaL_b in INaL: 0.005612
     * Gto_b in Ito: 0.084818
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001906
     * GK1_b in IK1: 0.161974
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.041751
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031324
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13892541, states[0] = -95.103380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26432836, states[0] = -95.081760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42466241, states[0] = -95.065479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58008466, states[0] = 23.648392, states[40]= 0.076154
Saving checkpoint... 
Iteration: 73842402, states[0] = -95.007622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89110770, states[0] = -30.803625, states[40]= 0.000427
Saving checkpoint... 
Iteration: 102497566, states[0] = -95.042336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113029252, states[0] = 18.744494, states[40]= 0.006197
Saving checkpoint... 
Iteration: 129915913, states[0] = -95.024595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145703479, states[0] = -94.841788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160145370, states[0] = -67.379212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169847326, states[0] = -94.998107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184833321, states[0] = -94.990456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199726101, states[0] = -94.881910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214541898, states[0] = 14.521549, states[40]= 0.005180
Saving checkpoint... 
Iteration: 226336989, states[0] = -94.992121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240627219, states[0] = -46.680184, states[40]= 0.000047
Saving checkpoint... 
Iteration: 254370093, states[0] = -95.007436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270031608, states[0] = 18.070124, states[40]= 0.005886
Saving checkpoint... 
Iteration: 285467142, states[0] = -95.032629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298844607, states[0] = -94.995942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312057342, states[0] = 8.486180, states[40]= 0.004881
Saving checkpoint... 
Iteration: 327897012, states[0] = -95.016749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340635813, states[0] = -55.972451, states[40]= 0.000010
Saving checkpoint... 
Iteration: 355765769, states[0] = -94.935647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364711001, states[0] = -94.854745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379089597, states[0] = -10.393876, states[40]= 0.002259
Saving checkpoint... 
Iteration: 393983956, states[0] = -95.035024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407188459, states[0] = -94.807874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422990293, states[0] = -95.035844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439991439, states[0] = -95.035980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451353569, states[0] = -95.000164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466241972, states[0] = -94.905714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473704391, states[0] = -94.841852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483831512, states[0] = -94.988757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494312574, states[0] = -94.976821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509056405, states[0] = 8.875126, states[40]= 0.004894
Saving checkpoint... 
Iteration: 525691438, states[0] = -94.814716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539796746, states[0] = -94.964955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557049990, states[0] = 11.449355, states[40]= 0.004982
Saving checkpoint... 
Iteration: 571735047, states[0] = -94.895513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585799149, states[0] = -94.966845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601004553, states[0] = 29.741911, states[40]= 0.153504
Saving checkpoint... 
Iteration: 617512989, states[0] = 22.374225, states[40]= 0.027250
Saving checkpoint... 
Iteration: 632517283, states[0] = 21.639644, states[40]= 0.013109
Saving checkpoint... 
Iteration: 645414233, states[0] = -95.021431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657266847, states[0] = -94.936638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671705971, states[0] = -94.844848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683025676, states[0] = 19.792375, states[40]= 0.006928
Saving checkpoint... 
Iteration: 697040741, states[0] = 14.948530, states[40]= 0.005225
Saving checkpoint... 
Iteration: 711368474, states[0] = -95.006436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724509357, states[0] = 23.328300, states[40]= 0.061675
Saving checkpoint... 
Iteration: 737807384, states[0] = -94.972988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748724540, states[0] = -94.878643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757444439, states[0] = -95.028256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771638012, states[0] = -58.435763, states[40]= 0.000007
Saving checkpoint... 
Iteration: 787090570, states[0] = -11.254437, states[40]= 0.002090
Saving checkpoint... 
Iteration: 802114266, states[0] = -33.681683, states[40]= 0.000306
Saving checkpoint... 
Iteration: 818003155, states[0] = 36.228341, states[40]= 0.140062
Saving checkpoint... 
Iteration: 834950252, states[0] = -95.029326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851606489, states[0] = -26.242262, states[40]= 0.000645
Saving checkpoint... 
Iteration: 864590696, states[0] = -11.367011, states[40]= 0.002068
Saving checkpoint... 
Iteration: 881854112, states[0] = -95.000139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900438909, states[0] = -95.027042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917108810, states[0] = -28.452977, states[40]= 0.000539
Saving checkpoint... 
Iteration: 934271403, states[0] = -94.941339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946802467, states[0] = -94.969190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957195397, states[0] = -94.823058, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551_1_r848482053_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_551_1_r848482053_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.265350
     * GNaL_b in INaL: 0.005612
     * Gto_b in Ito: 0.084818
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001906
     * GK1_b in IK1: 0.161974
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.041751
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031324
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 957195397
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.823058 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 969868375, states[0] = -95.006230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984784523, states[0] = -94.954150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002183613, states[0] = -94.793857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017261510, states[0] = -94.930395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029853383, states[0] = -94.999707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047243494, states[0] = -94.907474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064283139, states[0] = -94.952823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080172700, states[0] = -94.651652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096841343, states[0] = -94.993740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111957770, states[0] = -95.030509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126413294, states[0] = -95.020876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142100414, states[0] = -20.466718, states[40]= 0.000936
Saving checkpoint... 
Iteration: 1157973858, states[0] = -95.033088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169361844, states[0] = -95.003391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180890007, states[0] = -95.013970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195363820, states[0] = -95.004213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209976848, states[0] = -95.033498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224655607, states[0] = -83.173966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240275130, states[0] = -94.944967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255775198, states[0] = -94.945026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271138700, states[0] = -59.217247, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1286080879, states[0] = -3.583721, states[40]= 0.003678
Saving checkpoint... 
Iteration: 1298738647, states[0] = -94.900400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311600123, states[0] = -20.189785, states[40]= 0.000954
Saving checkpoint... 
Iteration: 1326027613, states[0] = 19.263982, states[40]= 0.006486
Saving checkpoint... 
Iteration: 1342360263, states[0] = -95.002598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350317809, states[0] = -94.979795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362796046, states[0] = -94.963859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377504691, states[0] = 29.301382, states[40]= 0.152201
Saving checkpoint... 
Iteration: 1393390718, states[0] = -95.014067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409378852, states[0] = -95.009964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425243449, states[0] = -94.907168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435067318, states[0] = 4.054523, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1445945950, states[0] = -95.028113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458970064, states[0] = -95.032315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472885429, states[0] = -95.012248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486340340, states[0] = -94.992965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499892839, states[0] = -95.014684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515420352, states[0] = -60.083661, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1531399778, states[0] = -95.175573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542890539, states[0] = -95.293269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557590740, states[0] = -95.300655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575274548, states[0] = -95.293485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591276098, states[0] = -12.243058, states[40]= 0.002158
Saving checkpoint... 
Iteration: 1608915209, states[0] = 22.169408, states[40]= 0.019578
Saving checkpoint... 
Iteration: 1625945992, states[0] = -95.271036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635646383, states[0] = 9.237970, states[40]= 0.005736
Saving checkpoint... 
Iteration: 1652767501, states[0] = -4.175890, states[40]= 0.004016
Saving checkpoint... 
Iteration: 1669789126, states[0] = -95.311203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686354983, states[0] = 4.457892, states[40]= 0.005333
Saving checkpoint... 
Iteration: 1701508802, states[0] = -95.219728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718337608, states[0] = -95.262206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735414202, states[0] = -95.228803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749185198, states[0] = -95.173421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765268425, states[0] = -4.976596, states[40]= 0.003837
Saving checkpoint... 
Iteration: 1782491369, states[0] = -95.186681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799339601, states[0] = -95.264663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814723721, states[0] = -94.920112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831885471, states[0] = -95.039950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847520512, states[0] = 20.854728, states[40]= 0.009240
Saving checkpoint... 
Iteration: 1863328610, states[0] = -94.997227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880217215, states[0] = -94.872027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895897472, states[0] = -95.020037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912746006, states[0] = -94.912929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925171916, states[0] = -94.623605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943798324, states[0] = -94.966301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962327817, states[0] = -94.986196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980848284, states[0] = -94.996964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999805266, states[0] = -94.970766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016781104, states[0] = -94.950370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028078083, states[0] = -1.769058, states[40]= 0.003996
Saving checkpoint... 
Iteration: 2045045727, states[0] = 13.090756, states[40]= 0.005065
Saving checkpoint... 
Iteration: 2063636073, states[0] = -56.261732, states[40]= 0.000010
Saving checkpoint... 
Iteration: 2081185675, states[0] = -94.799512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098334979, states[0] = -94.989632, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.911794
 - CaMKt in component CaMK (millimolar): 0.006976
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.553236
 - nass in component intracellular_ions (millimolar): 6.553296
 - ki in component intracellular_ions (millimolar): 145.424184
 - kss in component intracellular_ions (millimolar): 145.424164
 - cansr in component intracellular_ions (millimolar): 1.312567
 - cajsr in component intracellular_ions (millimolar): 1.274655
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880173
 - hs in component INa (dimensionless): 0.880169
 - j in component INa (dimensionless): 0.880139
 - hsp in component INa (dimensionless): 0.726155
 - jp in component INa (dimensionless): 0.880120
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710312
 - hLp in component INaL (dimensionless): 0.452690
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622045
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697094
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935993
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330561
 - xs1 in component IKs (dimensionless): 0.240042
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:38:04 (23828): called boinc_finish(0)

</stderr_txt>
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