𝕏

Task 55992281

Name HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_141_1
Workunit 26590785
Created 3 Jul 2024, 21:40:54 UTC
Sent 3 Jul 2024, 23:22:26 UTC
Report deadline 7 Jul 2024, 8:58:26 UTC
Received 4 Jul 2024, 7:26:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240196
Run time 1 hours 34 min 20 sec
CPU time 1 hours 34 min 20 sec
Validate state Valid
Credit 62.19
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.00 MB
Peak swap size 1.59 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_141.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_141_1_r549273760_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703234041194824_ORdGradInc_k_26-Pueyo_APDR-conf_141_1_r549273760_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.509746
     * GNaL_b in INaL: 0.005465
     * Gto_b in Ito: 0.086167
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032214
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.164780
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.394258
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035608
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8249125, states[0] = -95.041741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20664029, states[0] = -94.557399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33106659, states[0] = -29.479681, states[40]= 0.000475
Saving checkpoint... 
Iteration: 45397979, states[0] = -95.062599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57690743, states[0] = -94.857616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69924631, states[0] = -95.055883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82208003, states[0] = -94.882833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94722493, states[0] = -94.905743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106879018, states[0] = -95.034578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115572399, states[0] = 1.056576, states[40]= 0.004374
Saving checkpoint... 
Iteration: 128594259, states[0] = -15.472250, states[40]= 0.001402
Saving checkpoint... 
Iteration: 141335702, states[0] = -95.013066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153989545, states[0] = -95.055665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166523458, states[0] = 20.109285, states[40]= 0.007593
Saving checkpoint... 
Iteration: 179130913, states[0] = -51.843021, states[40]= 0.000020
Saving checkpoint... 
Iteration: 191898346, states[0] = -95.036910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204308684, states[0] = -94.995297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216655209, states[0] = -84.995310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229089706, states[0] = -11.133772, states[40]= 0.002109
Saving checkpoint... 
Iteration: 241387759, states[0] = -95.033347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253809911, states[0] = -94.995924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265921811, states[0] = -95.042737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278293000, states[0] = -94.983260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287230203, states[0] = -94.911829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299807223, states[0] = -94.993986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312415893, states[0] = -95.041243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325179266, states[0] = -94.806138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337545957, states[0] = 12.755748, states[40]= 0.005028
Saving checkpoint... 
Iteration: 349987392, states[0] = -95.054219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362468032, states[0] = -95.051497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374919520, states[0] = -95.042082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387335755, states[0] = -95.011408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399773788, states[0] = -94.965942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412142564, states[0] = -65.281146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 424599504, states[0] = -20.366163, states[40]= 0.000936
Saving checkpoint... 
Iteration: 436963078, states[0] = -95.050669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449237678, states[0] = -94.922786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461676570, states[0] = -94.788445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473961327, states[0] = -95.050362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486108239, states[0] = -28.756505, states[40]= 0.000515
Saving checkpoint... 
Iteration: 498349425, states[0] = -95.018141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510518043, states[0] = 21.258518, states[40]= 0.011829
Saving checkpoint... 
Iteration: 522832538, states[0] = -95.009584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535146748, states[0] = -70.942171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547539381, states[0] = 15.199026, states[40]= 0.005252
Saving checkpoint... 
Iteration: 559908027, states[0] = -95.039040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572228793, states[0] = -94.909438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584517160, states[0] = 21.415616, states[40]= 0.013236
Saving checkpoint... 
Iteration: 596764295, states[0] = -94.955978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609126553, states[0] = -47.090123, states[40]= 0.000043
Saving checkpoint... 
Iteration: 617592305, states[0] = -13.507963, states[40]= 0.001688
Saving checkpoint... 
Iteration: 629988014, states[0] = -95.054115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642357057, states[0] = -95.021476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654761555, states[0] = -94.952918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666942796, states[0] = -95.046935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679453940, states[0] = -95.048981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692108010, states[0] = -28.535749, states[40]= 0.000526
Saving checkpoint... 
Iteration: 704595759, states[0] = -16.774788, states[40]= 0.001245
Saving checkpoint... 
Iteration: 717476875, states[0] = -95.052567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730042185, states[0] = 14.174416, states[40]= 0.005136
Saving checkpoint... 
Iteration: 742485479, states[0] = -95.053717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755180017, states[0] = -94.809309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767550100, states[0] = 11.152794, states[40]= 0.004950
Saving checkpoint... 
Iteration: 779952771, states[0] = -95.048711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792370055, states[0] = -95.026672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804654512, states[0] = -83.777200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817081509, states[0] = -4.487869, states[40]= 0.003494
Saving checkpoint... 
Iteration: 828616881, states[0] = -37.167423, states[40]= 0.000190
Saving checkpoint... 
Iteration: 841174312, states[0] = -94.761791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853611072, states[0] = -31.492238, states[40]= 0.000390
Saving checkpoint... 
Iteration: 865758942, states[0] = -94.949819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878053289, states[0] = 9.883827, states[40]= 0.004905
Saving checkpoint... 
Iteration: 890330423, states[0] = -95.008175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902656004, states[0] = -86.284215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914864685, states[0] = -95.024486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927143032, states[0] = -65.878284, states[40]= 0.000002
Saving checkpoint... 
Iteration: 939365166, states[0] = -95.024663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951685867, states[0] = -94.827486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964098222, states[0] = -19.134892, states[40]= 0.001024
Saving checkpoint... 
Iteration: 976344324, states[0] = -95.015398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988659680, states[0] = -91.088290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001026712, states[0] = 19.280120, states[40]= 0.006624
Saving checkpoint... 
Iteration: 1013234748, states[0] = -94.918175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025464624, states[0] = -95.050538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037746567, states[0] = -94.934544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046278464, states[0] = -94.970029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058590773, states[0] = -12.093255, states[40]= 0.001930
Saving checkpoint... 
Iteration: 1070863947, states[0] = -95.024087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083224548, states[0] = -94.902347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095506201, states[0] = 25.618577, states[40]= 0.123949
Saving checkpoint... 
Iteration: 1107843599, states[0] = -95.014958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120122043, states[0] = -42.366241, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1132478005, states[0] = -95.052460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144789243, states[0] = -94.979566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157051725, states[0] = 10.510363, states[40]= 0.004926
Saving checkpoint... 
Iteration: 1169406850, states[0] = -95.038332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181804100, states[0] = -94.991172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194126854, states[0] = -47.410904, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1206521153, states[0] = 20.642208, states[40]= 0.008781
Saving checkpoint... 
Iteration: 1218753922, states[0] = -94.943671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227626060, states[0] = -46.565050, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1239895662, states[0] = -95.035091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252313109, states[0] = -94.997380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264708278, states[0] = -94.873712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277128758, states[0] = -49.457890, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1289559706, states[0] = 7.213236, states[40]= 0.004813
Saving checkpoint... 
Iteration: 1301823579, states[0] = -95.003949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314278040, states[0] = -94.969456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322992752, states[0] = -95.054259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335518717, states[0] = 21.133768, states[40]= 0.010954
Saving checkpoint... 
Iteration: 1344023633, states[0] = 20.074873, states[40]= 0.007527
Saving checkpoint... 
Iteration: 1356435871, states[0] = -95.045104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368933505, states[0] = -95.044601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381349247, states[0] = -95.017490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392173726, states[0] = -94.751541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404106580, states[0] = -27.159024, states[40]= 0.000591
Saving checkpoint... 
Iteration: 1416566105, states[0] = 4.327830, states[40]= 0.004662
Saving checkpoint... 
Iteration: 1429221602, states[0] = -94.897267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441769084, states[0] = -94.960515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454316514, states[0] = -94.999472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466854423, states[0] = -95.019791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479646800, states[0] = -71.016279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492279812, states[0] = -94.971000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504679204, states[0] = -95.127956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516885892, states[0] = -21.640091, states[40]= 0.000903
Saving checkpoint... 
Iteration: 1529134467, states[0] = 15.228810, states[40]= 0.006489
Saving checkpoint... 
Iteration: 1541676340, states[0] = -95.295921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554086347, states[0] = -23.762886, states[40]= 0.000772
Saving checkpoint... 
Iteration: 1566531220, states[0] = -95.260490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578938697, states[0] = 12.928754, states[40]= 0.006124
Saving checkpoint... 
Iteration: 1591232137, states[0] = 15.927027, states[40]= 0.006739
Saving checkpoint... 
Iteration: 1603637310, states[0] = -91.831709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615998531, states[0] = -95.216405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628186004, states[0] = -24.032127, states[40]= 0.000756
Saving checkpoint... 
Iteration: 1640442014, states[0] = 11.218822, states[40]= 0.005915
Saving checkpoint... 
Iteration: 1649327890, states[0] = -95.264464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661504979, states[0] = -45.493153, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1673832932, states[0] = -86.149124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686159002, states[0] = -95.124072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698431646, states[0] = -83.855867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710744796, states[0] = -94.786381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723184847, states[0] = -95.321988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735536126, states[0] = 14.064418, states[40]= 0.006322
Saving checkpoint... 
Iteration: 1748189390, states[0] = -27.853311, states[40]= 0.000552
Saving checkpoint... 
Iteration: 1760810053, states[0] = -51.669800, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1772675078, states[0] = -95.314540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784834434, states[0] = -88.596817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797215507, states[0] = -95.247043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813410720, states[0] = -95.084156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825643332, states[0] = -69.516864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1837845812, states[0] = -95.038609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850109260, states[0] = -30.731486, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1862429572, states[0] = -95.054556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874871321, states[0] = -95.034163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887047773, states[0] = 11.968093, states[40]= 0.004991
Saving checkpoint... 
Iteration: 1899272023, states[0] = -94.967002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911576966, states[0] = -1.568839, states[40]= 0.004019
Saving checkpoint... 
Iteration: 1923920167, states[0] = -95.043024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936510663, states[0] = 22.594618, states[40]= 0.045301
Saving checkpoint... 
Iteration: 1949150914, states[0] = -77.605809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961676218, states[0] = -94.785159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970274890, states[0] = -94.966435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982635443, states[0] = -56.861344, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1994954271, states[0] = -95.048368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007349973, states[0] = -95.017530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019543716, states[0] = 13.601926, states[40]= 0.005086
Saving checkpoint... 
Iteration: 2031700460, states[0] = -94.858092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043927280, states[0] = -95.042810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056159524, states[0] = -90.936806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068687840, states[0] = -94.831421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081307011, states[0] = -94.992636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093791436, states[0] = -94.980738, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930440
 - CaMKt in component CaMK (millimolar): 0.006944
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.598272
 - nass in component intracellular_ions (millimolar): 6.598332
 - ki in component intracellular_ions (millimolar): 145.379562
 - kss in component intracellular_ions (millimolar): 145.379542
 - cansr in component intracellular_ions (millimolar): 1.310383
 - cajsr in component intracellular_ions (millimolar): 1.272589
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880496
 - hs in component INa (dimensionless): 0.880491
 - j in component INa (dimensionless): 0.880463
 - hsp in component INa (dimensionless): 0.726765
 - jp in component INa (dimensionless): 0.880444
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711145
 - hLp in component INaL (dimensionless): 0.454279
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623442
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698868
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937062
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001594
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326616
 - xs1 in component IKs (dimensionless): 0.238135
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:25:53 (21648): called boinc_finish(0)

</stderr_txt>
]]>


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