𝕏

Task 55991935

Name HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_581_1
Workunit 26590618
Created 3 Jul 2024, 21:31:45 UTC
Sent 3 Jul 2024, 23:21:54 UTC
Report deadline 7 Jul 2024, 8:57:54 UTC
Received 4 Jul 2024, 5:51:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 59419
Run time 1 hours 44 min 56 sec
CPU time 1 hours 44 min 25 sec
Validate state Valid
Credit 62.79
Device peak FLOPS 4.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.32 MB
Peak swap size 4.63 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_581_1_r102712153_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_581_1_r102712153_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.806211
     * GNaL_b in INaL: 0.005564
     * Gto_b in Ito: 0.083832
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032120
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.162418
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.376606
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036660
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10274836, states[0] = -95.056119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25405046, states[0] = -95.084122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40370523, states[0] = -95.052951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55593347, states[0] = -15.520763, states[40]= 0.001404
Saving checkpoint... 
Iteration: 70881537, states[0] = -95.037591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85764614, states[0] = -94.958418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100986978, states[0] = -95.053163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116007476, states[0] = 24.567312, states[40]= 0.094580
Saving checkpoint... 
Iteration: 131417488, states[0] = -95.037490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146277851, states[0] = -94.964913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161118224, states[0] = -38.535607, states[40]= 0.000155
Saving checkpoint... 
Iteration: 176050228, states[0] = 11.175058, states[40]= 0.004994
Saving checkpoint... 
Iteration: 186080585, states[0] = -3.800532, states[40]= 0.003637
Saving checkpoint... 
Iteration: 196485670, states[0] = -95.048026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206720806, states[0] = -94.890352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221881398, states[0] = -95.024889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236847359, states[0] = -95.010993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251903618, states[0] = -95.031688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266647304, states[0] = -71.688515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281586026, states[0] = -7.895521, states[40]= 0.002784
Saving checkpoint... 
Iteration: 296491074, states[0] = -95.048342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306555338, states[0] = 9.120197, states[40]= 0.004915
Saving checkpoint... 
Iteration: 321682830, states[0] = -94.812783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336486873, states[0] = -95.047777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351401148, states[0] = -95.030866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366412060, states[0] = -95.033825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381480621, states[0] = -95.046918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396154455, states[0] = -83.458164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411230555, states[0] = -94.905662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425978209, states[0] = -95.046557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440821693, states[0] = -94.996899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455872636, states[0] = -95.021445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470758141, states[0] = -94.942592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485676444, states[0] = -94.777938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500638578, states[0] = -60.430043, states[40]= 0.000005
Saving checkpoint... 
Iteration: 515748740, states[0] = -94.931111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530765166, states[0] = -94.950419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545996955, states[0] = -95.048878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561033152, states[0] = 17.479470, states[40]= 0.005782
Saving checkpoint... 
Iteration: 575919587, states[0] = -95.035574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590995069, states[0] = -95.048628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605913461, states[0] = -95.034036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621040019, states[0] = 15.082288, states[40]= 0.005294
Saving checkpoint... 
Iteration: 636081271, states[0] = -4.262585, states[40]= 0.003547
Saving checkpoint... 
Iteration: 651148905, states[0] = -74.104780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666385883, states[0] = -95.025973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676701335, states[0] = -94.854111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691689283, states[0] = -94.829052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706709934, states[0] = -94.870567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721956794, states[0] = -95.043067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736666976, states[0] = -94.311682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752088122, states[0] = -9.664782, states[40]= 0.002408
Saving checkpoint... 
Iteration: 767093668, states[0] = -14.722897, states[40]= 0.001506
Saving checkpoint... 
Iteration: 782128083, states[0] = -48.721511, states[40]= 0.000033
Saving checkpoint... 
Iteration: 797188398, states[0] = -94.826987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812228911, states[0] = -94.902871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827260319, states[0] = -94.944871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842148791, states[0] = -73.927162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857517113, states[0] = 21.663803, states[40]= 0.013613
Saving checkpoint... 
Iteration: 869829543, states[0] = -95.001251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884797108, states[0] = -94.979623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899934911, states[0] = -95.038819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910355960, states[0] = -95.014408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925315621, states[0] = -94.992780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940262398, states[0] = -94.947136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955255165, states[0] = -94.938786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969924242, states[0] = -95.036431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975296136, states[0] = -94.978806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990539493, states[0] = 15.274138, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1000886750, states[0] = -95.026053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016203561, states[0] = -94.858269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031281322, states[0] = -94.966185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046253312, states[0] = -94.936492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061377837, states[0] = -95.022972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076152349, states[0] = -79.795557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091112865, states[0] = -33.197333, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1106154416, states[0] = -83.389229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121304265, states[0] = -94.984864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136244769, states[0] = -94.925550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151468634, states[0] = -95.044715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165263800, states[0] = -94.948543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180183184, states[0] = -94.813339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195209536, states[0] = -94.869527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210501968, states[0] = 45.242536, states[40]= 0.084186
Saving checkpoint... 
Iteration: 1225505481, states[0] = 27.410402, states[40]= 0.137083
Saving checkpoint... 
Iteration: 1240566485, states[0] = 4.200799, states[40]= 0.004675
Saving checkpoint... 
Iteration: 1255547169, states[0] = 12.383376, states[40]= 0.005053
Saving checkpoint... 
Iteration: 1266029459, states[0] = 18.648837, states[40]= 0.006247
Saving checkpoint... 
Iteration: 1281549949, states[0] = 11.295835, states[40]= 0.004998
Saving checkpoint... 
Iteration: 1298058961, states[0] = 7.596548, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1314101460, states[0] = -22.189102, states[40]= 0.000829
Saving checkpoint... 
Iteration: 1330080664, states[0] = -3.838085, states[40]= 0.003629
Saving checkpoint... 
Iteration: 1346524775, states[0] = 19.970108, states[40]= 0.007297
Saving checkpoint... 
Iteration: 1362791938, states[0] = -94.975190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378754080, states[0] = -94.937220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394898613, states[0] = -95.029489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411256938, states[0] = -94.940607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427384140, states[0] = -95.024926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443362767, states[0] = -95.016969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459690589, states[0] = -94.831458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475816239, states[0] = -94.992841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492100878, states[0] = -21.629431, states[40]= 0.000859
Saving checkpoint... 
Iteration: 1508294586, states[0] = -95.158967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524270340, states[0] = -95.274748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540760532, states[0] = -95.279399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556866083, states[0] = -95.131037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572712883, states[0] = -54.520099, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1588626055, states[0] = -72.945352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1604860841, states[0] = -95.125573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620826204, states[0] = -95.259230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637005357, states[0] = -95.227559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653340382, states[0] = 12.130746, states[40]= 0.006073
Saving checkpoint... 
Iteration: 1669302979, states[0] = -42.989777, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1685319871, states[0] = -95.251552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701478680, states[0] = -95.174676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717664797, states[0] = -95.140063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733841233, states[0] = -94.015165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749840631, states[0] = -95.279052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766155741, states[0] = 3.766171, states[40]= 0.005267
Saving checkpoint... 
Iteration: 1782375674, states[0] = -12.531925, states[40]= 0.002100
Saving checkpoint... 
Iteration: 1798310554, states[0] = -52.136069, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1814037203, states[0] = 15.464309, states[40]= 0.005430
Saving checkpoint... 
Iteration: 1830438073, states[0] = -95.067908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846674264, states[0] = -94.783242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862839687, states[0] = -95.017360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879040313, states[0] = 14.872168, states[40]= 0.005280
Saving checkpoint... 
Iteration: 1895202223, states[0] = -94.859532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911201017, states[0] = -94.855469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927247914, states[0] = -94.930878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943562997, states[0] = 5.797555, states[40]= 0.004774
Saving checkpoint... 
Iteration: 1959610172, states[0] = -30.622940, states[40]= 0.000427
Saving checkpoint... 
Iteration: 1975657960, states[0] = -88.956935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991726798, states[0] = -94.899031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007798052, states[0] = -94.979778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024051685, states[0] = 10.603807, states[40]= 0.004969
Saving checkpoint... 
Iteration: 2040030865, states[0] = 18.214951, states[40]= 0.006045
Saving checkpoint... 
Iteration: 2056034993, states[0] = 16.861644, states[40]= 0.005615
Saving checkpoint... 
Iteration: 2072384037, states[0] = -95.024468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088616519, states[0] = -36.781509, states[40]= 0.000199
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.924109
 - CaMKt in component CaMK (millimolar): 0.006865
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.590110
 - nass in component intracellular_ions (millimolar): 6.590170
 - ki in component intracellular_ions (millimolar): 145.389007
 - kss in component intracellular_ions (millimolar): 145.388988
 - cansr in component intracellular_ions (millimolar): 1.305885
 - cajsr in component intracellular_ions (millimolar): 1.268192
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880386
 - hs in component INa (dimensionless): 0.880382
 - j in component INa (dimensionless): 0.880354
 - hsp in component INa (dimensionless): 0.726558
 - jp in component INa (dimensionless): 0.880335
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710951
 - hLp in component INaL (dimensionless): 0.453997
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623324
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698616
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936601
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001579
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329530
 - xs1 in component IKs (dimensionless): 0.238517
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:49:31 (6196): called boinc_finish(0)

</stderr_txt>
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