𝕏

Task 55991730

Name HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_477_0
Workunit 26590516
Created 3 Jul 2024, 21:31:40 UTC
Sent 3 Jul 2024, 23:14:24 UTC
Report deadline 7 Jul 2024, 8:50:24 UTC
Received 4 Jul 2024, 6:40:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236853
Run time 2 hours 53 min 58 sec
CPU time 2 hours 53 min 53 sec
Validate state Valid
Credit 61.67
Device peak FLOPS 3.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.39 MB
Peak swap size 2.53 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_477.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_477_0_r747834192_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_477_0_r747834192_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.773079
     * GNaL_b in INaL: 0.005700
     * Gto_b in Ito: 0.085695
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032091
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.164661
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.826227
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029212
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13191530, states[0] = -94.919216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26382260, states[0] = -95.070343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39574071, states[0] = -0.542993, states[40]= 0.004209
Saving checkpoint... 
Iteration: 52771312, states[0] = -94.971532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65963785, states[0] = -95.053027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79140018, states[0] = -62.150906, states[40]= 0.000004
Saving checkpoint... 
Iteration: 92336895, states[0] = -95.005218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105512402, states[0] = 22.331255, states[40]= 0.030895
Saving checkpoint... 
Iteration: 118700964, states[0] = -94.846821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131867842, states[0] = -95.014880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145056187, states[0] = 8.837181, states[40]= 0.004893
Saving checkpoint... 
Iteration: 158206022, states[0] = -94.854622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171334724, states[0] = -94.997849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184497133, states[0] = -95.043175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189421187, states[0] = -95.029896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202610962, states[0] = -30.837423, states[40]= 0.000425
Saving checkpoint... 
Iteration: 215762662, states[0] = -94.939619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228935677, states[0] = -95.032897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242106486, states[0] = -26.547089, states[40]= 0.000628
Saving checkpoint... 
Iteration: 255280920, states[0] = -94.958257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268454307, states[0] = -95.036419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281628345, states[0] = -48.279324, states[40]= 0.000036
Saving checkpoint... 
Iteration: 294802888, states[0] = -94.976636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307975056, states[0] = -95.039735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321148342, states[0] = -72.215363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334313049, states[0] = -94.983849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347454089, states[0] = -95.036296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360595421, states[0] = -16.008843, states[40]= 0.001339
Saving checkpoint... 
Iteration: 373737240, states[0] = -94.906589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386920636, states[0] = -95.029251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400133460, states[0] = -53.843412, states[40]= 0.000015
Saving checkpoint... 
Iteration: 413299729, states[0] = -94.974135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426467140, states[0] = -95.038439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439657699, states[0] = -87.725940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452846321, states[0] = -95.003028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466033346, states[0] = 17.418194, states[40]= 0.005698
Saving checkpoint... 
Iteration: 479220106, states[0] = -94.879259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492409452, states[0] = -95.026307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505599803, states[0] = -20.176578, states[40]= 0.000955
Saving checkpoint... 
Iteration: 518788645, states[0] = -94.964988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531978744, states[0] = -95.040112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545169186, states[0] = -94.501978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558359683, states[0] = -95.009112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571548522, states[0] = 11.925938, states[40]= 0.005003
Saving checkpoint... 
Iteration: 584735806, states[0] = -94.904340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597942299, states[0] = -95.033903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611130548, states[0] = -50.653697, states[40]= 0.000025
Saving checkpoint... 
Iteration: 624262212, states[0] = -94.938667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637392407, states[0] = -95.021215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650521262, states[0] = 20.748968, states[40]= 0.008774
Saving checkpoint... 
Iteration: 663650247, states[0] = -75.170649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676779674, states[0] = -94.956756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689893070, states[0] = -95.021391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703024188, states[0] = 20.070066, states[40]= 0.007375
Saving checkpoint... 
Iteration: 716155939, states[0] = -84.928605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729282023, states[0] = -94.958923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742413491, states[0] = -95.027220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755543116, states[0] = 13.979889, states[40]= 0.005133
Saving checkpoint... 
Iteration: 768658290, states[0] = -88.564936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781761955, states[0] = -94.938274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794865975, states[0] = -95.011598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807968335, states[0] = -95.038383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821132288, states[0] = -52.552800, states[40]= 0.000018
Saving checkpoint... 
Iteration: 834319861, states[0] = -94.987991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847507965, states[0] = 23.967490, states[40]= 0.085730
Saving checkpoint... 
Iteration: 860671287, states[0] = -94.638985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873859777, states[0] = -95.008950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887047584, states[0] = 12.288076, states[40]= 0.005020
Saving checkpoint... 
Iteration: 900235449, states[0] = -94.903607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913413564, states[0] = -95.027129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926604375, states[0] = -24.530699, states[40]= 0.000723
Saving checkpoint... 
Iteration: 939778528, states[0] = -94.955494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952979204, states[0] = -95.039907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966145822, states[0] = -68.615387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979309371, states[0] = -94.980889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980396852, states[0] = -95.022376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993527030, states[0] = 19.326205, states[40]= 0.006598
Saving checkpoint... 
Iteration: 1006686303, states[0] = -94.811229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019847569, states[0] = -95.003272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033017281, states[0] = 21.527003, states[40]= 0.013125
Saving checkpoint... 
Iteration: 1046207914, states[0] = -94.856704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059378638, states[0] = -95.016282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072546603, states[0] = 12.664193, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1085714309, states[0] = -94.868607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098916598, states[0] = -95.027790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112083881, states[0] = -5.937132, states[40]= 0.003206
Saving checkpoint... 
Iteration: 1125251321, states[0] = -94.925285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138411318, states[0] = -95.026394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139638020, states[0] = -58.969426, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1152636423, states[0] = -57.150514, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1165750378, states[0] = -94.924058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178863406, states[0] = -95.010293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191972633, states[0] = -95.038796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205081016, states[0] = -3.863577, states[40]= 0.003627
Saving checkpoint... 
Iteration: 1218169097, states[0] = -94.493486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231267918, states[0] = -94.944557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244382647, states[0] = -95.017583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257497180, states[0] = -95.042048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270608319, states[0] = -28.290859, states[40]= 0.000545
Saving checkpoint... 
Iteration: 1283721200, states[0] = -94.880616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296832396, states[0] = -94.995175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309941975, states[0] = -95.033382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323063558, states[0] = 5.687128, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1336172702, states[0] = -94.692677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349276317, states[0] = -94.953085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362400512, states[0] = -95.023226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375523372, states[0] = 20.268698, states[40]= 0.007683
Saving checkpoint... 
Iteration: 1388686397, states[0] = -94.811218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395776171, states[0] = -94.952912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408843433, states[0] = -95.000977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421965556, states[0] = -95.037548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435085745, states[0] = -7.391734, states[40]= 0.002895
Saving checkpoint... 
Iteration: 1448220708, states[0] = -94.879668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461353255, states[0] = -95.005671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474486858, states[0] = -95.040617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487619579, states[0] = -39.211330, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1500752521, states[0] = -94.860055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513838863, states[0] = 13.566985, states[40]= 0.006146
Saving checkpoint... 
Iteration: 1526924094, states[0] = -95.214783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540008232, states[0] = -47.365880, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1553087654, states[0] = -95.297779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566176120, states[0] = -95.146478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579279937, states[0] = -16.607055, states[40]= 0.001419
Saving checkpoint... 
Iteration: 1592392844, states[0] = -95.311198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605505487, states[0] = -95.213818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618619599, states[0] = -62.947999, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1631732690, states[0] = 15.772561, states[40]= 0.006715
Saving checkpoint... 
Iteration: 1644843515, states[0] = -95.270217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657938238, states[0] = -92.156815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671023358, states[0] = 19.503340, states[40]= 0.008889
Saving checkpoint... 
Iteration: 1684109238, states[0] = -95.222547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698707078, states[0] = -47.312459, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1711782273, states[0] = -95.307236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724852682, states[0] = -95.064917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737950373, states[0] = 6.952796, states[40]= 0.005548
Saving checkpoint... 
Iteration: 1751048311, states[0] = -95.276184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764127835, states[0] = -75.619329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777199961, states[0] = -95.319483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790270919, states[0] = -95.142568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803340896, states[0] = -95.056179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816417710, states[0] = -95.069518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829523458, states[0] = 19.950779, states[40]= 0.007557
Saving checkpoint... 
Iteration: 1842962233, states[0] = -95.056360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856067589, states[0] = 3.474485, states[40]= 0.004631
Saving checkpoint... 
Iteration: 1869174545, states[0] = -94.755013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882268645, states[0] = -94.951068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895376400, states[0] = -95.019027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908483993, states[0] = -95.042714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921588513, states[0] = -9.793958, states[40]= 0.002384
Saving checkpoint... 
Iteration: 1934699512, states[0] = -94.840802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947600096, states[0] = -20.506588, states[40]= 0.000933
Saving checkpoint... 
Iteration: 1960496393, states[0] = -95.042054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973377684, states[0] = -95.015710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986263505, states[0] = -94.939478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999220481, states[0] = -94.879065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013793062, states[0] = -94.967837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028331049, states[0] = -94.993972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041350131, states[0] = -95.003843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054877998, states[0] = -95.015393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069378116, states[0] = -95.015414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083575641, states[0] = -0.455356, states[40]= 0.004196
Saving checkpoint... 
Iteration: 2096715451, states[0] = -94.869971, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.917670
 - CaMKt in component CaMK (millimolar): 0.006977
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.570775
 - nass in component intracellular_ions (millimolar): 6.570836
 - ki in component intracellular_ions (millimolar): 145.406433
 - kss in component intracellular_ions (millimolar): 145.406414
 - cansr in component intracellular_ions (millimolar): 1.313455
 - cajsr in component intracellular_ions (millimolar): 1.275586
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880275
 - hs in component INa (dimensionless): 0.880270
 - j in component INa (dimensionless): 0.880241
 - hsp in component INa (dimensionless): 0.726347
 - jp in component INa (dimensionless): 0.880222
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710630
 - hLp in component INaL (dimensionless): 0.453369
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622618
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697831
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936404
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001609
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329782
 - xs1 in component IKs (dimensionless): 0.239297
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:36:39 (2516): called boinc_finish(0)

</stderr_txt>
]]>


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