𝕏

Task 55991516

Name HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_467_0
Workunit 26590409
Created 3 Jul 2024, 21:31:35 UTC
Sent 3 Jul 2024, 23:12:42 UTC
Report deadline 7 Jul 2024, 8:48:42 UTC
Received 6 Jul 2024, 4:27:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234951
Run time 2 hours 29 min 14 sec
CPU time 2 hours 28 min 52 sec
Validate state Valid
Credit 62.63
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_467.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_467_0_r1963323089_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_467_0_r1963323089_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.835506
     * GNaL_b in INaL: 0.005913
     * Gto_b in Ito: 0.086777
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031575
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.166227
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.412405
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037296
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14551235, states[0] = 9.885559, states[40]= 0.004904
Saving checkpoint... 
Iteration: 29116206, states[0] = -36.881826, states[40]= 0.000198
Saving checkpoint... 
Iteration: 44251460, states[0] = -94.950213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58557067, states[0] = 8.552725, states[40]= 0.004852
Saving checkpoint... 
Iteration: 73013961, states[0] = 22.012370, states[40]= 0.022376
Saving checkpoint... 
Iteration: 87503846, states[0] = 32.182381, states[40]= 0.153544
Saving checkpoint... 
Iteration: 102199685, states[0] = -94.841901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116571762, states[0] = 2.254526, states[40]= 0.004475
Saving checkpoint... 
Iteration: 130803512, states[0] = -94.972354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145498571, states[0] = -95.035766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160625059, states[0] = -42.698574, states[40]= 0.000086
Saving checkpoint... 
Iteration: 174975871, states[0] = -95.032038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189569007, states[0] = 3.688734, states[40]= 0.004594
Saving checkpoint... 
Iteration: 204970470, states[0] = -95.030890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219804214, states[0] = -94.970783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234066716, states[0] = 4.770065, states[40]= 0.004668
Saving checkpoint... 
Iteration: 248742206, states[0] = -94.907970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263121665, states[0] = -39.254135, states[40]= 0.000144
Saving checkpoint... 
Iteration: 277787651, states[0] = -94.957539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291870598, states[0] = -95.005971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306640499, states[0] = -59.266829, states[40]= 0.000006
Saving checkpoint... 
Iteration: 320979361, states[0] = -95.031857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336585645, states[0] = -6.175506, states[40]= 0.003125
Saving checkpoint... 
Iteration: 350937572, states[0] = -95.024812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365335007, states[0] = -94.989787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379845214, states[0] = -94.994978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394875394, states[0] = -95.007671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410753049, states[0] = -94.921818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425094224, states[0] = -13.400424, states[40]= 0.001693
Saving checkpoint... 
Iteration: 439263883, states[0] = -94.934336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454866444, states[0] = -95.004239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469235769, states[0] = -94.898685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484190856, states[0] = -94.818184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499109535, states[0] = -27.683051, states[40]= 0.000579
Saving checkpoint... 
Iteration: 513716276, states[0] = -94.867452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527997067, states[0] = -95.033953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542498944, states[0] = -95.034159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557146216, states[0] = -66.171315, states[40]= 0.000002
Saving checkpoint... 
Iteration: 571392590, states[0] = -95.013325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585790469, states[0] = -94.959698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600170627, states[0] = -94.441167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615019131, states[0] = 21.269909, states[40]= 0.010527
Saving checkpoint... 
Iteration: 629586137, states[0] = -6.548864, states[40]= 0.003046
Saving checkpoint... 
Iteration: 644729149, states[0] = -94.888614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659439005, states[0] = -95.024902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674015025, states[0] = 21.943344, states[40]= 0.018490
Saving checkpoint... 
Iteration: 689501789, states[0] = 46.458142, states[40]= 0.075483
Saving checkpoint... 
Iteration: 704197164, states[0] = -94.831287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719056280, states[0] = 9.237314, states[40]= 0.004860
Saving checkpoint... 
Iteration: 733921066, states[0] = -95.020944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748746627, states[0] = -94.913488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763397568, states[0] = -95.014706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778156870, states[0] = -82.738458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792404857, states[0] = -95.016765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807833779, states[0] = -94.988844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822027162, states[0] = 19.449011, states[40]= 0.006527
Saving checkpoint... 
Iteration: 837012702, states[0] = 22.305837, states[40]= 0.028932
Saving checkpoint... 
Iteration: 851602451, states[0] = -21.054010, states[40]= 0.000899
Saving checkpoint... 
Iteration: 866736764, states[0] = -94.899874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881648305, states[0] = -68.952663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896698095, states[0] = -94.833040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911957575, states[0] = -95.028158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926745485, states[0] = -94.911875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942195658, states[0] = -94.828068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956474727, states[0] = -95.030797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971096125, states[0] = -15.145883, states[40]= 0.001436
Saving checkpoint... 
Iteration: 985355946, states[0] = -94.999536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999965349, states[0] = -95.029365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015059285, states[0] = 8.009552, states[40]= 0.004821
Saving checkpoint... 
Iteration: 1029657655, states[0] = -84.112033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044306505, states[0] = -94.971747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059237473, states[0] = -94.900770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073797010, states[0] = -94.964664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088670332, states[0] = -94.407364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103597736, states[0] = -16.642691, states[40]= 0.001254
Saving checkpoint... 
Iteration: 1118653897, states[0] = -77.532149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133251182, states[0] = -94.919054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147931936, states[0] = -95.023130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163097316, states[0] = -16.251348, states[40]= 0.001299
Saving checkpoint... 
Iteration: 1177479801, states[0] = -95.031368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192189086, states[0] = -94.813696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206730695, states[0] = -94.890640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221627079, states[0] = -44.700856, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1236385214, states[0] = -95.010545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250885086, states[0] = -95.010493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266112745, states[0] = -30.700899, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1280697678, states[0] = -94.831957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295378544, states[0] = -95.008228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310145544, states[0] = -65.312122, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1325121515, states[0] = -39.103264, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1339862666, states[0] = -95.002157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354470567, states[0] = -95.029938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369185246, states[0] = -94.803429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383652342, states[0] = -74.958566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398290797, states[0] = -94.959456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412943400, states[0] = -95.025289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427486807, states[0] = -95.032136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442056193, states[0] = 9.272468, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1456493741, states[0] = -95.032975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471081958, states[0] = -3.552767, states[40]= 0.003651
Saving checkpoint... 
Iteration: 1485952527, states[0] = -95.026924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500534149, states[0] = -95.173456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515780533, states[0] = -95.116693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530617243, states[0] = 21.770888, states[40]= 0.014840
Saving checkpoint... 
Iteration: 1545352300, states[0] = 6.626996, states[40]= 0.005454
Saving checkpoint... 
Iteration: 1559713889, states[0] = 22.514512, states[40]= 0.024473
Saving checkpoint... 
Iteration: 1574074880, states[0] = -95.284052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588365876, states[0] = -95.117251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603145908, states[0] = -95.260762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617778546, states[0] = -95.151347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632471901, states[0] = -95.136142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646800430, states[0] = -37.779025, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1660922972, states[0] = -65.276956, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1675320900, states[0] = -62.460872, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1689926563, states[0] = 18.472307, states[40]= 0.007744
Saving checkpoint... 
Iteration: 1704043908, states[0] = 10.704996, states[40]= 0.005815
Saving checkpoint... 
Iteration: 1718905921, states[0] = -95.207635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733423527, states[0] = 19.574375, states[40]= 0.008767
Saving checkpoint... 
Iteration: 1747688350, states[0] = -95.174303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762745851, states[0] = -95.263151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776985087, states[0] = -21.152017, states[40]= 0.000950
Saving checkpoint... 
Iteration: 1791868991, states[0] = -95.285684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807243700, states[0] = -94.956786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822372534, states[0] = -95.040546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837826398, states[0] = -95.006392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852249854, states[0] = -94.931667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867503583, states[0] = 33.467538, states[40]= 0.150226
Saving checkpoint... 
Iteration: 1882749808, states[0] = -94.922748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898053653, states[0] = 10.214159, states[40]= 0.004893
Saving checkpoint... 
Iteration: 1912762642, states[0] = -94.934406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927286305, states[0] = -94.956816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941963048, states[0] = -95.029353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957082334, states[0] = -3.830381, states[40]= 0.003599
Saving checkpoint... 
Iteration: 1971638773, states[0] = -57.338183, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1985940441, states[0] = -95.024567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000779572, states[0] = -94.949318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015694676, states[0] = -94.825418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030244768, states[0] = -94.910242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044627492, states[0] = -45.130546, states[40]= 0.000060
Saving checkpoint... 
Iteration: 2059474601, states[0] = -95.030058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073901106, states[0] = -95.014868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088786570, states[0] = -94.955388, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909125
 - CaMKt in component CaMK (millimolar): 0.006959
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.561988
 - nass in component intracellular_ions (millimolar): 6.562048
 - ki in component intracellular_ions (millimolar): 145.416375
 - kss in component intracellular_ions (millimolar): 145.416356
 - cansr in component intracellular_ions (millimolar): 1.308542
 - cajsr in component intracellular_ions (millimolar): 1.270461
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880127
 - hs in component INa (dimensionless): 0.880122
 - j in component INa (dimensionless): 0.880094
 - hsp in component INa (dimensionless): 0.726069
 - jp in component INa (dimensionless): 0.880076
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709919
 - hLp in component INaL (dimensionless): 0.451649
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620313
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695067
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935026
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001587
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331584
 - xs1 in component IKs (dimensionless): 0.242816
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:27:20 (38091): called boinc_finish(0)

</stderr_txt>
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