𝕏

Task 55991475

Name HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_263_1
Workunit 26590388
Created 3 Jul 2024, 21:31:30 UTC
Sent 3 Jul 2024, 23:21:49 UTC
Report deadline 7 Jul 2024, 8:57:49 UTC
Received 4 Jul 2024, 4:29:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234919
Run time 2 hours 39 min 17 sec
CPU time 2 hours 28 min 7 sec
Validate state Valid
Credit 62.50
Device peak FLOPS 3.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.29 MB
Peak swap size 5.23 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_263.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_263_1_r1819925866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_263_1_r1819925866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.739379
     * GNaL_b in INaL: 0.005446
     * Gto_b in Ito: 0.081189
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032382
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.159665
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.597510
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037350
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10094007, states[0] = -21.059039, states[40]= 0.000865
Saving checkpoint... 
Iteration: 24713782, states[0] = -94.900368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39295451, states[0] = -94.975617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53881499, states[0] = -95.007738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68579422, states[0] = -4.325224, states[40]= 0.003564
Saving checkpoint... 
Iteration: 83151433, states[0] = -82.015102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97779747, states[0] = -94.931316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112474358, states[0] = -95.009636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127082178, states[0] = -5.900119, states[40]= 0.003229
Saving checkpoint... 
Iteration: 141787393, states[0] = -94.933476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156343902, states[0] = -94.969907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170902995, states[0] = -94.991665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185428348, states[0] = -94.997725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199849887, states[0] = -94.971920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201537979, states[0] = 15.632132, states[40]= 0.005498
Saving checkpoint... 
Iteration: 215260989, states[0] = -94.905893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229863127, states[0] = -94.977476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244455880, states[0] = -95.002663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259012413, states[0] = 22.729163, states[40]= 0.031320
Saving checkpoint... 
Iteration: 273529758, states[0] = 18.468097, states[40]= 0.006345
Saving checkpoint... 
Iteration: 288123953, states[0] = -46.104204, states[40]= 0.000049
Saving checkpoint... 
Iteration: 302540364, states[0] = 14.746944, states[40]= 0.005361
Saving checkpoint... 
Iteration: 308198420, states[0] = -94.808505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322477940, states[0] = -95.005944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337098317, states[0] = -20.510442, states[40]= 0.000922
Saving checkpoint... 
Iteration: 351780806, states[0] = -94.925767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366397986, states[0] = -94.989382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381075803, states[0] = -1.402127, states[40]= 0.004075
Saving checkpoint... 
Iteration: 395667198, states[0] = -94.441984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410347402, states[0] = -94.970318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424966741, states[0] = -95.004237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439492865, states[0] = -95.007798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454074469, states[0] = -0.592407, states[40]= 0.004197
Saving checkpoint... 
Iteration: 468715689, states[0] = -94.840999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483361431, states[0] = -94.976500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497994735, states[0] = -95.007986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508140073, states[0] = -64.223777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 522731626, states[0] = -94.867030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537316119, states[0] = -94.952906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551932225, states[0] = -94.997874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566545866, states[0] = 12.620860, states[40]= 0.005148
Saving checkpoint... 
Iteration: 581169989, states[0] = -94.620544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595765877, states[0] = -94.910825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610475570, states[0] = -95.005436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625083296, states[0] = -6.663394, states[40]= 0.003064
Saving checkpoint... 
Iteration: 639798254, states[0] = -94.940266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654395043, states[0] = -94.988336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669072033, states[0] = 0.808721, states[40]= 0.004381
Saving checkpoint... 
Iteration: 683703752, states[0] = -94.818799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698390873, states[0] = -94.987027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712967051, states[0] = -95.004117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727603022, states[0] = -25.099556, states[40]= 0.000676
Saving checkpoint... 
Iteration: 742276704, states[0] = -94.921692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756955799, states[0] = -95.002266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771591925, states[0] = -14.310386, states[40]= 0.001573
Saving checkpoint... 
Iteration: 786106075, states[0] = -28.080693, states[40]= 0.000534
Saving checkpoint... 
Iteration: 800784713, states[0] = -94.929015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815407547, states[0] = -94.991803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830101542, states[0] = -23.655939, states[40]= 0.000746
Saving checkpoint... 
Iteration: 844679789, states[0] = -94.763102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859325080, states[0] = -94.958237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874054418, states[0] = 9.146464, states[40]= 0.004965
Saving checkpoint... 
Iteration: 888708579, states[0] = -94.827862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903388842, states[0] = -94.986264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917989815, states[0] = -95.007147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932549361, states[0] = 11.227204, states[40]= 0.005061
Saving checkpoint... 
Iteration: 947113838, states[0] = -35.718131, states[40]= 0.000224
Saving checkpoint... 
Iteration: 961661828, states[0] = -93.243157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976093471, states[0] = -15.794846, states[40]= 0.001367
Saving checkpoint... 
Iteration: 990743037, states[0] = -94.883085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005362609, states[0] = -94.976682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019947157, states[0] = -95.000573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034476283, states[0] = -95.005290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049068029, states[0] = 2.933782, states[40]= 0.004603
Saving checkpoint... 
Iteration: 1063682271, states[0] = -94.771598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078352298, states[0] = -94.972197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092969466, states[0] = -95.004264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107407639, states[0] = -94.991658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122107648, states[0] = -29.619661, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1136693249, states[0] = -94.797410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151352926, states[0] = -94.972438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166021975, states[0] = 20.674099, states[40]= 0.008726
Saving checkpoint... 
Iteration: 1180601978, states[0] = -24.080970, states[40]= 0.000725
Saving checkpoint... 
Iteration: 1195285435, states[0] = -94.929419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209937711, states[0] = -94.998631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224532451, states[0] = 17.587809, states[40]= 0.005981
Saving checkpoint... 
Iteration: 1239078428, states[0] = -3.097217, states[40]= 0.003786
Saving checkpoint... 
Iteration: 1253753090, states[0] = -94.895836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268367096, states[0] = -94.978330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282996492, states[0] = -95.007736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297677965, states[0] = -94.754225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312308142, states[0] = -94.947112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326964708, states[0] = -95.003396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341608498, states[0] = -30.452460, states[40]= 0.000424
Saving checkpoint... 
Iteration: 1356291634, states[0] = -94.934584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370874350, states[0] = -94.981024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385481897, states[0] = -95.005857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400095394, states[0] = -17.659490, states[40]= 0.001156
Saving checkpoint... 
Iteration: 1414812467, states[0] = -94.950001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429446933, states[0] = -95.000294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443989141, states[0] = -95.006758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458624292, states[0] = -46.463457, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1473297125, states[0] = -94.938907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487966631, states[0] = -95.003602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502586884, states[0] = -95.101554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515423660, states[0] = -67.405765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1529888328, states[0] = -95.132771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544423498, states[0] = 19.676434, states[40]= 0.009195
Saving checkpoint... 
Iteration: 1558982326, states[0] = -95.137624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573510809, states[0] = 23.859421, states[40]= 0.045046
Saving checkpoint... 
Iteration: 1588079656, states[0] = -95.138909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602601531, states[0] = 48.892598, states[40]= 0.044823
Saving checkpoint... 
Iteration: 1617217138, states[0] = -95.212132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631675639, states[0] = -95.278300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646326096, states[0] = -95.226174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660851206, states[0] = 6.095798, states[40]= 0.005518
Saving checkpoint... 
Iteration: 1675384353, states[0] = -95.153658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689990638, states[0] = -30.251179, states[40]= 0.000430
Saving checkpoint... 
Iteration: 1704512279, states[0] = -95.206169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719015477, states[0] = 22.201697, states[40]= 0.019358
Saving checkpoint... 
Iteration: 1733373639, states[0] = -95.277673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747932413, states[0] = -86.486026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762445720, states[0] = -95.251029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771763381, states[0] = -95.268806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786259161, states[0] = 1.165112, states[40]= 0.004980
Saving checkpoint... 
Iteration: 1800910149, states[0] = -95.065397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815355268, states[0] = -95.017720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829816707, states[0] = -94.982647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844335933, states[0] = -94.983428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858900431, states[0] = -95.001966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873480207, states[0] = -95.013600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888026304, states[0] = 19.458051, states[40]= 0.007036
Saving checkpoint... 
Iteration: 1902590493, states[0] = -13.137231, states[40]= 0.001762
Saving checkpoint... 
Iteration: 1916955678, states[0] = -95.003829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931263844, states[0] = -94.909341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945737705, states[0] = -94.876094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960231033, states[0] = -94.865904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974807109, states[0] = -94.946380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989367988, states[0] = -94.978487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999517456, states[0] = 21.690652, states[40]= 0.013336
Saving checkpoint... 
Iteration: 2013969813, states[0] = -95.003866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028528159, states[0] = 18.964822, states[40]= 0.006627
Saving checkpoint... 
Iteration: 2043067547, states[0] = 3.176114, states[40]= 0.004624
Saving checkpoint... 
Iteration: 2057719637, states[0] = -94.846879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067822147, states[0] = -94.955759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082269787, states[0] = -94.914022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096835158, states[0] = -94.963134, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883499
 - CaMKt in component CaMK (millimolar): 0.006728
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.566250
 - nass in component intracellular_ions (millimolar): 6.566309
 - ki in component intracellular_ions (millimolar): 145.414738
 - kss in component intracellular_ions (millimolar): 145.414719
 - cansr in component intracellular_ions (millimolar): 1.298762
 - cajsr in component intracellular_ions (millimolar): 1.261384
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879682
 - hs in component INa (dimensionless): 0.879678
 - j in component INa (dimensionless): 0.879649
 - hsp in component INa (dimensionless): 0.725231
 - jp in component INa (dimensionless): 0.879631
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710243
 - hLp in component INaL (dimensionless): 0.453875
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.624781
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.700265
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937538
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001554
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330242
 - xs1 in component IKs (dimensionless): 0.235710
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:15:42 (10396): called boinc_finish(0)

</stderr_txt>
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