𝕏

Task 55991262

Name HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_436_0
Workunit 26590283
Created 3 Jul 2024, 21:31:24 UTC
Sent 3 Jul 2024, 23:22:26 UTC
Report deadline 7 Jul 2024, 8:58:26 UTC
Received 4 Jul 2024, 16:00:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240196
Run time 1 hours 34 min 3 sec
CPU time 1 hours 34 min 3 sec
Validate state Valid
Credit 61.29
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.00 MB
Peak swap size 1.49 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_436.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_436_0_r504209311_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233114138990_ORdGradInc_k_26-Pueyo_APDR-conf_436_0_r504209311_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.303146
     * GNaL_b in INaL: 0.005562
     * Gto_b in Ito: 0.084423
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031361
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.165331
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.345228
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034646
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8965031, states[0] = -95.172530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21390501, states[0] = -95.115628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33794904, states[0] = -95.043699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46326180, states[0] = -95.050249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58949604, states[0] = -95.083035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71510957, states[0] = 22.801627, states[40]= 0.042644
Saving checkpoint... 
Iteration: 84137691, states[0] = -58.055517, states[40]= 0.000007
Saving checkpoint... 
Iteration: 96654492, states[0] = -81.288279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105896343, states[0] = -95.055310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118482987, states[0] = -95.071632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131094530, states[0] = -14.498777, states[40]= 0.001534
Saving checkpoint... 
Iteration: 143654481, states[0] = -80.595804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156196403, states[0] = -94.866332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168929438, states[0] = -95.059654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181572395, states[0] = 1.699259, states[40]= 0.004443
Saving checkpoint... 
Iteration: 194167566, states[0] = -94.171449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206759743, states[0] = -94.965490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219449646, states[0] = -95.063093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231986917, states[0] = -95.068795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244467084, states[0] = -95.065934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255391209, states[0] = -95.048757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267611689, states[0] = -30.583505, states[40]= 0.000436
Saving checkpoint... 
Iteration: 280149907, states[0] = -72.801721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292787640, states[0] = -94.992921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305262865, states[0] = -94.968694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317695552, states[0] = -94.863342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330227593, states[0] = -94.921716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342673375, states[0] = -94.714937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351545757, states[0] = 13.174010, states[40]= 0.005075
Saving checkpoint... 
Iteration: 364115176, states[0] = -33.916394, states[40]= 0.000295
Saving checkpoint... 
Iteration: 377026229, states[0] = 19.714526, states[40]= 0.006868
Saving checkpoint... 
Iteration: 389584199, states[0] = -5.595281, states[40]= 0.003263
Saving checkpoint... 
Iteration: 402013988, states[0] = 22.277328, states[40]= 0.022607
Saving checkpoint... 
Iteration: 414667036, states[0] = -94.049784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427372224, states[0] = -95.042047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439838497, states[0] = -95.027075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452231595, states[0] = -94.927833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464469683, states[0] = -95.066114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476862952, states[0] = -95.038370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489255496, states[0] = -94.960097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501663836, states[0] = -92.824965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514097895, states[0] = -17.519613, states[40]= 0.001168
Saving checkpoint... 
Iteration: 526367578, states[0] = -95.040199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538644152, states[0] = -64.889501, states[40]= 0.000002
Saving checkpoint... 
Iteration: 550910960, states[0] = -95.054196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563727955, states[0] = -94.922136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576298122, states[0] = -95.001272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588771685, states[0] = -94.977836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601155808, states[0] = -82.716274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613513282, states[0] = 22.401690, states[40]= 0.025936
Saving checkpoint... 
Iteration: 625869886, states[0] = -95.041036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638165642, states[0] = -93.645752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650376582, states[0] = -95.043517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662557917, states[0] = 8.376145, states[40]= 0.004873
Saving checkpoint... 
Iteration: 674772476, states[0] = -94.978579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687017890, states[0] = 21.601039, states[40]= 0.012320
Saving checkpoint... 
Iteration: 699292653, states[0] = -94.996851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711175640, states[0] = -94.771951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723701893, states[0] = -94.875840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735958903, states[0] = -95.064225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744802086, states[0] = -95.004173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757302069, states[0] = -95.004152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769800913, states[0] = -95.003281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782257088, states[0] = -94.961800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794740397, states[0] = -94.940426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807083920, states[0] = -5.389353, states[40]= 0.003306
Saving checkpoint... 
Iteration: 819480453, states[0] = -95.067453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831821744, states[0] = -95.017385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844147392, states[0] = -69.148861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856529064, states[0] = 18.916857, states[40]= 0.006292
Saving checkpoint... 
Iteration: 869030954, states[0] = 18.347393, states[40]= 0.006016
Saving checkpoint... 
Iteration: 881375330, states[0] = -95.042921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893555780, states[0] = 9.254423, states[40]= 0.004903
Saving checkpoint... 
Iteration: 905737433, states[0] = -94.936171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917953674, states[0] = -95.063213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930155250, states[0] = -81.728820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942483592, states[0] = -95.067802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954857679, states[0] = -95.035855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967541777, states[0] = 14.656054, states[40]= 0.005202
Saving checkpoint... 
Iteration: 979912345, states[0] = -95.054294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990365832, states[0] = -95.039222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006329293, states[0] = -95.021727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018615270, states[0] = -34.006216, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1031355686, states[0] = -95.034939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043924297, states[0] = -95.057181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056910639, states[0] = -95.053802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064948149, states[0] = -95.062124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077341942, states[0] = -95.028443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089591695, states[0] = -11.774927, states[40]= 0.001983
Saving checkpoint... 
Iteration: 1101763969, states[0] = -94.969404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114178511, states[0] = -94.807494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126484232, states[0] = -95.067775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138661623, states[0] = -91.153827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151074630, states[0] = 0.513616, states[40]= 0.004307
Saving checkpoint... 
Iteration: 1163448157, states[0] = -95.062065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175852514, states[0] = -95.033432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188179492, states[0] = -94.814848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200508158, states[0] = 24.068857, states[40]= 0.081422
Saving checkpoint... 
Iteration: 1211959866, states[0] = -95.064094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220340897, states[0] = -95.027827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230689313, states[0] = -94.849348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242847756, states[0] = -95.031181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255207529, states[0] = -94.886365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267295823, states[0] = -94.999050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279370394, states[0] = -95.040830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291765688, states[0] = -94.971151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304150586, states[0] = -73.844009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316465824, states[0] = -95.064995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328959720, states[0] = -95.063998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338416899, states[0] = -95.055227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350942010, states[0] = -95.060776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359431271, states[0] = -95.058551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372011843, states[0] = 22.684024, states[40]= 0.035066
Saving checkpoint... 
Iteration: 1384379921, states[0] = -95.044254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396619289, states[0] = -37.904965, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1409121972, states[0] = -40.561237, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1417649951, states[0] = -72.863395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429980356, states[0] = -95.067066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442540825, states[0] = 15.003271, states[40]= 0.005242
Saving checkpoint... 
Iteration: 1455114453, states[0] = -33.221427, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1464070431, states[0] = 2.719876, states[40]= 0.004542
Saving checkpoint... 
Iteration: 1476511635, states[0] = 22.730213, states[40]= 0.036703
Saving checkpoint... 
Iteration: 1488996049, states[0] = -95.069034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501463738, states[0] = -95.252561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513983662, states[0] = -95.157457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523514184, states[0] = -52.395623, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1536021446, states[0] = 20.581275, states[40]= 0.010152
Saving checkpoint... 
Iteration: 1546219742, states[0] = 21.061914, states[40]= 0.011555
Saving checkpoint... 
Iteration: 1554689509, states[0] = -25.870613, states[40]= 0.000660
Saving checkpoint... 
Iteration: 1566789259, states[0] = -95.203421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579042004, states[0] = -93.694836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591317113, states[0] = -58.212406, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1603748438, states[0] = -95.299471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616471107, states[0] = -6.960112, states[40]= 0.003357
Saving checkpoint... 
Iteration: 1628762732, states[0] = -0.263205, states[40]= 0.004744
Saving checkpoint... 
Iteration: 1641091393, states[0] = -28.584011, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1653372917, states[0] = -8.727990, states[40]= 0.002934
Saving checkpoint... 
Iteration: 1665438323, states[0] = -91.375087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677779542, states[0] = -95.190819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689831841, states[0] = -95.282291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698391210, states[0] = -28.419696, states[40]= 0.000529
Saving checkpoint... 
Iteration: 1710600034, states[0] = -91.141136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722625721, states[0] = 18.821279, states[40]= 0.008109
Saving checkpoint... 
Iteration: 1734943634, states[0] = 10.753137, states[40]= 0.005877
Saving checkpoint... 
Iteration: 1747331780, states[0] = -81.000534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759518095, states[0] = 21.405504, states[40]= 0.013506
Saving checkpoint... 
Iteration: 1771711647, states[0] = -95.253128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784190575, states[0] = -27.732019, states[40]= 0.000563
Saving checkpoint... 
Iteration: 1796244013, states[0] = -94.441585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808531078, states[0] = 17.685194, states[40]= 0.005882
Saving checkpoint... 
Iteration: 1820902900, states[0] = -95.087716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833032570, states[0] = 17.506349, states[40]= 0.005807
Saving checkpoint... 
Iteration: 1845134223, states[0] = -54.873347, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1853863114, states[0] = -95.051587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866016926, states[0] = 21.690975, states[40]= 0.013908
Saving checkpoint... 
Iteration: 1877988601, states[0] = -95.074682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890174232, states[0] = -94.753722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902466880, states[0] = -95.068078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914472242, states[0] = -95.067895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926620221, states[0] = -38.932014, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1939014796, states[0] = 22.130758, states[40]= 0.019500
Saving checkpoint... 
Iteration: 1951290747, states[0] = -94.995258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963404374, states[0] = -95.052054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975724743, states[0] = -94.916476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988098120, states[0] = -17.747052, states[40]= 0.001146
Saving checkpoint... 
Iteration: 2000142336, states[0] = -62.675382, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2012463964, states[0] = -95.064353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024674996, states[0] = -94.758609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036923027, states[0] = -95.056288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049081895, states[0] = -3.952394, states[40]= 0.003594
Saving checkpoint... 
Iteration: 2061313641, states[0] = -95.011452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073553068, states[0] = 10.344390, states[40]= 0.004941
Saving checkpoint... 
Iteration: 2085879854, states[0] = -95.043763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097989319, states[0] = -95.067796, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944952
 - CaMKt in component CaMK (millimolar): 0.006897
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.533137
 - nass in component intracellular_ions (millimolar): 6.533196
 - ki in component intracellular_ions (millimolar): 145.445923
 - kss in component intracellular_ions (millimolar): 145.445904
 - cansr in component intracellular_ions (millimolar): 1.306194
 - cajsr in component intracellular_ions (millimolar): 1.268282
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880747
 - hs in component INa (dimensionless): 0.880742
 - j in component INa (dimensionless): 0.880714
 - hsp in component INa (dimensionless): 0.727238
 - jp in component INa (dimensionless): 0.880695
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711078
 - hLp in component INaL (dimensionless): 0.453360
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621595
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696576
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935472
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331857
 - xs1 in component IKs (dimensionless): 0.241253
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:00:13 (22488): called boinc_finish(0)

</stderr_txt>
]]>


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