𝕏

Task 55990930

Name HuVeMOp_20240703233044701546_ORdGradInc_k_26-Drouin_EPI_3000-conf_981_0
Workunit 26590117
Created 3 Jul 2024, 21:31:14 UTC
Sent 3 Jul 2024, 23:13:52 UTC
Report deadline 6 Jul 2024, 23:13:52 UTC
Received 5 Jul 2024, 6:04:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 53 sec
CPU time 1 hours 27 min 55 sec
Validate state Valid
Credit 42.88
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Drouin_EPI_3000-conf_981.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Drouin_EPI_3000-conf_981_0_r386325072_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Drouin_EPI_3000-conf_981_0_r386325072_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.584612
     * GNaL_b in INaL: 0.006105
     * Gto_b in Ito: 0.082682
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032254
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.163879
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.574919
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035673
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7683151, states[0] = -88.522728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15909642, states[0] = -94.363689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23944474, states[0] = -94.318688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31885558, states[0] = -94.255302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39139644, states[0] = -33.729622, states[40]= 0.000258
Saving checkpoint... 
Iteration: 46946459, states[0] = -94.291207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56222209, states[0] = -94.326631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64669928, states[0] = -72.132696, states[40]= 0.000004
Saving checkpoint... 
Iteration: 72960882, states[0] = -94.321706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80738558, states[0] = -94.312105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89959446, states[0] = -94.307275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98214019, states[0] = -94.339292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106607832, states[0] = -3.013803, states[40]= 0.000223
Saving checkpoint... 
Iteration: 114630162, states[0] = -94.342404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122132902, states[0] = -94.343402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131643742, states[0] = -94.325118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139704240, states[0] = -93.651428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148317941, states[0] = -94.319517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156213397, states[0] = -93.721729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164077169, states[0] = -94.343100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171820076, states[0] = -94.341901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180843722, states[0] = -94.340927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189152823, states[0] = -52.693804, states[40]= 0.000067
Saving checkpoint... 
Iteration: 197545080, states[0] = -94.331366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204726317, states[0] = -94.345584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213103334, states[0] = 0.161202, states[40]= 0.000168
Saving checkpoint... 
Iteration: 221735395, states[0] = -94.323245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229675692, states[0] = -84.417970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237941715, states[0] = -94.335971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246619988, states[0] = -94.345452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255026411, states[0] = 25.713906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263226308, states[0] = -94.344972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271926962, states[0] = -94.300767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280093356, states[0] = -94.328320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288142263, states[0] = -40.125463, states[40]= 0.000245
Saving checkpoint... 
Iteration: 297117844, states[0] = -13.088721, states[40]= 0.000250
Saving checkpoint... 
Iteration: 305186374, states[0] = -94.345144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314391450, states[0] = -94.337297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322956420, states[0] = -94.315056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330987899, states[0] = -94.332364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339472191, states[0] = -94.320969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346970844, states[0] = -94.320362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354925472, states[0] = -94.334986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362991436, states[0] = -94.312708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371424092, states[0] = -94.334780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379060821, states[0] = -94.328178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387740909, states[0] = -94.342556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396293436, states[0] = -94.106175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404511167, states[0] = -94.330049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413335975, states[0] = -94.338303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421938163, states[0] = -94.304686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430231989, states[0] = -94.320182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438455992, states[0] = -94.312965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447185425, states[0] = -92.872400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454826005, states[0] = -94.182574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463227149, states[0] = -94.319822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471741125, states[0] = -94.341163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479697720, states[0] = -94.320699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488694308, states[0] = -94.320684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497070259, states[0] = -94.338373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504773606, states[0] = -94.339464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512850745, states[0] = -94.314567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521647978, states[0] = -94.322020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529310984, states[0] = -94.315652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537548702, states[0] = -94.335269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545515493, states[0] = -94.327508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553659016, states[0] = -60.092859, states[40]= 0.000026
Saving checkpoint... 
Iteration: 562419428, states[0] = -94.311534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571065115, states[0] = -94.324800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579834511, states[0] = -94.335612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588732820, states[0] = -94.339476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597712312, states[0] = -94.339866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605952711, states[0] = -94.309807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615553923, states[0] = -94.334648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624687944, states[0] = -94.339858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633363468, states[0] = -94.238419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641372461, states[0] = -94.332811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649403652, states[0] = -94.310588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657885171, states[0] = -94.331925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665768166, states[0] = -94.314924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673585602, states[0] = 10.937674, states[40]= 0.000027
Saving checkpoint... 
Iteration: 681625909, states[0] = -94.338566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690724963, states[0] = -94.338013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699842210, states[0] = -94.333275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708928924, states[0] = -94.328959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717167846, states[0] = -71.512597, states[40]= 0.000005
Saving checkpoint... 
Iteration: 725716943, states[0] = -94.315866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734169642, states[0] = -94.338194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743484086, states[0] = -94.325719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752395978, states[0] = -94.329837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761256287, states[0] = -94.335861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770521032, states[0] = -94.323522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779229081, states[0] = -94.336431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787630497, states[0] = -26.844366, states[40]= 0.000372
Saving checkpoint... 
Iteration: 796532831, states[0] = 26.188470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804835415, states[0] = -94.331847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813398940, states[0] = -94.271880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821729990, states[0] = -94.313769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831064058, states[0] = 20.442760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838961015, states[0] = -94.308436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846399057, states[0] = -94.271430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854837937, states[0] = -94.309326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862868121, states[0] = -94.240269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871601520, states[0] = 1.447405, states[40]= 0.000145
Saving checkpoint... 
Iteration: 879916365, states[0] = -94.326731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888668689, states[0] = -94.335635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897344841, states[0] = -94.207980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906030249, states[0] = 26.078230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914431817, states[0] = -94.325406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924322936, states[0] = -94.168656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932908512, states[0] = -94.305729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941886357, states[0] = -94.306284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950065726, states[0] = -94.330429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958194063, states[0] = -94.312907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966204375, states[0] = -93.641300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974314247, states[0] = -94.329994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983682329, states[0] = -94.312949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992609551, states[0] = -94.315845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000865501, states[0] = -94.234813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009182383, states[0] = -94.312524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018281701, states[0] = -94.308579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026082465, states[0] = 12.539889, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1034773031, states[0] = -94.308620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043019191, states[0] = -94.322064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052625375, states[0] = -94.314169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060037627, states[0] = -94.317951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068575240, states[0] = -94.329363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077249099, states[0] = -93.925264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085582776, states[0] = -94.315485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094005854, states[0] = -94.318330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102140580, states[0] = -94.312708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110515916, states[0] = -94.320285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119063821, states[0] = 20.528381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127765012, states[0] = -94.307376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136642192, states[0] = -94.312066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145208408, states[0] = -94.330888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153604109, states[0] = -0.411670, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1161522308, states[0] = -94.320714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169537127, states[0] = -94.316164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177615513, states[0] = -10.602588, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1185680110, states[0] = -94.330658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194055586, states[0] = 23.112882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202326100, states[0] = -94.325691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210457526, states[0] = -94.299630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220362019, states[0] = -94.323717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228382555, states[0] = -94.301651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236823468, states[0] = -94.325236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244587553, states[0] = -94.312634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252380448, states[0] = -94.301320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260427026, states[0] = -94.284464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269331305, states[0] = -94.178945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277472068, states[0] = -94.317444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285342368, states[0] = -94.302033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293487538, states[0] = -94.310164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301397130, states[0] = -94.320687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309808523, states[0] = -94.130504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319225731, states[0] = -94.327585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328623466, states[0] = -94.309677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337244632, states[0] = -94.326717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345331190, states[0] = -94.301415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354049023, states[0] = -94.312553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363547116, states[0] = 25.033190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371823196, states[0] = -94.323009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379809379, states[0] = -94.301597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388404202, states[0] = -94.318897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396992349, states[0] = -94.309832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404652522, states[0] = -94.327059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413515789, states[0] = -94.315241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421449350, states[0] = -94.316157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429961991, states[0] = -94.299031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438310584, states[0] = -94.300586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447435668, states[0] = -94.296349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456589157, states[0] = 9.040918, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1464697211, states[0] = -94.325809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473227011, states[0] = -93.793810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481864793, states[0] = -94.298019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489407041, states[0] = -94.296535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498236272, states[0] = -94.302301, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.169547
 - CaMKt in component CaMK (millimolar): 0.003646
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.202170
 - nass in component intracellular_ions (millimolar): 7.202309
 - ki in component intracellular_ions (millimolar): 144.430796
 - kss in component intracellular_ions (millimolar): 144.430778
 - cansr in component intracellular_ions (millimolar): 2.452018
 - cajsr in component intracellular_ions (millimolar): 2.452625
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003896
 - hf in component INa (dimensionless): 0.866701
 - hs in component INa (dimensionless): 0.866702
 - j in component INa (dimensionless): 0.866709
 - hsp in component INa (dimensionless): 0.701280
 - jp in component INa (dimensionless): 0.866713
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709507
 - hLp in component INaL (dimensionless): 0.513535
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991120
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005207
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024935
 - xs1 in component IKs (dimensionless): 0.068918
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997523
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:03:43 (81941): called boinc_finish(0)

</stderr_txt>
]]>


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