𝕏

Task 55990238

Name HuVeMOp_20240703233044701546_ORdGradInc_k_26-Pueyo_APDR-conf_132_0
Workunit 26589772
Created 3 Jul 2024, 21:30:53 UTC
Sent 3 Jul 2024, 23:10:59 UTC
Report deadline 7 Jul 2024, 8:46:59 UTC
Received 4 Jul 2024, 9:59:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241135
Run time 1 hours 35 min 58 sec
CPU time 1 hours 35 min 2 sec
Validate state Valid
Credit 62.18
Device peak FLOPS 6.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.81 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Pueyo_APDR-conf_132.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Pueyo_APDR-conf_132_0_r640261593_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703233044701546_ORdGradInc_k_26-Pueyo_APDR-conf_132_0_r640261593_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.114106
     * GNaL_b in INaL: 0.005955
     * Gto_b in Ito: 0.086105
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031937
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.166287
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.212065
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029036
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8829026, states[0] = -95.076980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22101683, states[0] = -23.677414, states[40]= 0.000762
Saving checkpoint... 
Iteration: 35732563, states[0] = -94.922611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46561669, states[0] = 6.416145, states[40]= 0.004805
Saving checkpoint... 
Iteration: 58404124, states[0] = -95.029927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71824993, states[0] = -94.990640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85222410, states[0] = -94.877999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98571730, states[0] = 2.087229, states[40]= 0.004495
Saving checkpoint... 
Iteration: 112129865, states[0] = -48.427045, states[40]= 0.000037
Saving checkpoint... 
Iteration: 125742750, states[0] = -94.903889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139342779, states[0] = -94.990631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152372372, states[0] = -95.003296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166073873, states[0] = 1.078719, states[40]= 0.004385
Saving checkpoint... 
Iteration: 179531286, states[0] = 18.284628, states[40]= 0.005841
Saving checkpoint... 
Iteration: 193151892, states[0] = -75.255516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206529654, states[0] = 18.775707, states[40]= 0.006048
Saving checkpoint... 
Iteration: 220297798, states[0] = -94.960316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233730871, states[0] = -94.884004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247293211, states[0] = -94.956486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260680456, states[0] = -94.775183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274355561, states[0] = -94.995178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287690425, states[0] = -94.807825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301171134, states[0] = -94.532325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314611059, states[0] = -29.553747, states[40]= 0.000498
Saving checkpoint... 
Iteration: 328301055, states[0] = -94.962656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341294700, states[0] = -94.957594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354358879, states[0] = -94.996575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367925014, states[0] = -95.018113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381712515, states[0] = -94.852422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395067132, states[0] = 4.479773, states[40]= 0.004683
Saving checkpoint... 
Iteration: 407259660, states[0] = -94.923009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420594505, states[0] = -14.037274, states[40]= 0.001608
Saving checkpoint... 
Iteration: 429768778, states[0] = -94.933202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438680053, states[0] = -94.772502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452329924, states[0] = -94.981892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465728853, states[0] = -94.880556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479360802, states[0] = -94.997323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492567349, states[0] = 4.377785, states[40]= 0.004676
Saving checkpoint... 
Iteration: 501568772, states[0] = 3.698834, states[40]= 0.004628
Saving checkpoint... 
Iteration: 514907767, states[0] = -95.013608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528626706, states[0] = -44.852418, states[40]= 0.000064
Saving checkpoint... 
Iteration: 542262308, states[0] = -94.925981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555825630, states[0] = -94.979284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569181955, states[0] = -94.782670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582991831, states[0] = -95.029678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596377367, states[0] = -95.003834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610092642, states[0] = -12.340234, states[40]= 0.001888
Saving checkpoint... 
Iteration: 618951691, states[0] = -95.023508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632776104, states[0] = -94.940604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646198758, states[0] = -94.825369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654755047, states[0] = -94.917303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668078368, states[0] = -1.475212, states[40]= 0.004040
Saving checkpoint... 
Iteration: 681827072, states[0] = -94.980064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695482195, states[0] = -95.028333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708942992, states[0] = -95.021783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722162544, states[0] = -91.579678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735804088, states[0] = -94.964678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749119924, states[0] = -38.031243, states[40]= 0.000176
Saving checkpoint... 
Iteration: 762625764, states[0] = -43.879406, states[40]= 0.000074
Saving checkpoint... 
Iteration: 776025256, states[0] = 19.977944, states[40]= 0.006920
Saving checkpoint... 
Iteration: 789742148, states[0] = -94.900264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803066813, states[0] = 4.629203, states[40]= 0.004692
Saving checkpoint... 
Iteration: 816476651, states[0] = -95.027466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830008183, states[0] = 23.801928, states[40]= 0.081533
Saving checkpoint... 
Iteration: 843836267, states[0] = -94.985190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856375961, states[0] = -95.003140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869936305, states[0] = -95.020301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878300713, states[0] = -94.962018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891497724, states[0] = -95.030194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905215923, states[0] = -94.858293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918618728, states[0] = -36.867128, states[40]= 0.000207
Saving checkpoint... 
Iteration: 932156713, states[0] = -83.537286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945674919, states[0] = -94.704534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959269179, states[0] = -94.933274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972581167, states[0] = -3.256942, states[40]= 0.003736
Saving checkpoint... 
Iteration: 986009207, states[0] = 23.275336, states[40]= 0.063954
Saving checkpoint... 
Iteration: 999456266, states[0] = -95.024077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013011849, states[0] = 22.529020, states[40]= 0.034521
Saving checkpoint... 
Iteration: 1026323035, states[0] = -94.977383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035041590, states[0] = 14.822423, states[40]= 0.005148
Saving checkpoint... 
Iteration: 1048343003, states[0] = -94.988601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062197417, states[0] = -94.822323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071001262, states[0] = 49.106338, states[40]= 0.046455
Saving checkpoint... 
Iteration: 1084524616, states[0] = 20.137047, states[40]= 0.007109
Saving checkpoint... 
Iteration: 1097903545, states[0] = -95.012028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111270933, states[0] = -94.935021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124675758, states[0] = -94.722733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137688892, states[0] = -94.803672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150873180, states[0] = -95.001894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164517329, states[0] = 21.635991, states[40]= 0.012805
Saving checkpoint... 
Iteration: 1177837761, states[0] = -94.985773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191477096, states[0] = -95.027281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204807513, states[0] = -94.966878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218670502, states[0] = -94.477962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230692365, states[0] = -94.811488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244329454, states[0] = -94.981089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257711974, states[0] = -94.850827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271503620, states[0] = 33.368689, states[40]= 0.155576
Saving checkpoint... 
Iteration: 1284946566, states[0] = -95.022099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298813736, states[0] = -94.971171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311561420, states[0] = 7.044158, states[40]= 0.004815
Saving checkpoint... 
Iteration: 1325250100, states[0] = -94.910614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338565964, states[0] = 5.022819, states[40]= 0.004716
Saving checkpoint... 
Iteration: 1352109041, states[0] = -27.651663, states[40]= 0.000590
Saving checkpoint... 
Iteration: 1365653401, states[0] = -77.726263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379326927, states[0] = -94.979511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392599170, states[0] = -18.385870, states[40]= 0.001096
Saving checkpoint... 
Iteration: 1405658676, states[0] = -86.822850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419293755, states[0] = -94.956089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427997278, states[0] = -95.029783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436788098, states[0] = -94.951254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450101556, states[0] = -20.626736, states[40]= 0.000934
Saving checkpoint... 
Iteration: 1462203505, states[0] = -94.834399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475659537, states[0] = -88.118152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484620506, states[0] = -38.600719, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1498022419, states[0] = 20.650199, states[40]= 0.007968
Saving checkpoint... 
Iteration: 1511656323, states[0] = -95.222794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524102472, states[0] = -38.468034, states[40]= 0.000165
Saving checkpoint... 
Iteration: 1537490993, states[0] = -95.276065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546239216, states[0] = 13.231593, states[40]= 0.006099
Saving checkpoint... 
Iteration: 1555389825, states[0] = -95.156984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568770939, states[0] = -6.398167, states[40]= 0.003501
Saving checkpoint... 
Iteration: 1582199312, states[0] = -95.298333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595343066, states[0] = -95.250993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609035391, states[0] = -86.826389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617521008, states[0] = -95.223533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630972735, states[0] = -95.129268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644288321, states[0] = -95.295377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657830266, states[0] = 17.013551, states[40]= 0.006975
Saving checkpoint... 
Iteration: 1671008739, states[0] = 24.399233, states[40]= 0.070118
Saving checkpoint... 
Iteration: 1684557107, states[0] = 3.462344, states[40]= 0.005233
Saving checkpoint... 
Iteration: 1697898684, states[0] = -95.187173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711419000, states[0] = -95.222005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724302004, states[0] = -95.193453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737817142, states[0] = -95.219160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750969689, states[0] = -95.122448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764569363, states[0] = -95.280919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777833647, states[0] = 15.555370, states[40]= 0.006552
Saving checkpoint... 
Iteration: 1791217768, states[0] = -95.220113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804640664, states[0] = -65.272594, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1817860582, states[0] = -95.035711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831071935, states[0] = 1.354507, states[40]= 0.004445
Saving checkpoint... 
Iteration: 1844613868, states[0] = -33.353328, states[40]= 0.000326
Saving checkpoint... 
Iteration: 1858085157, states[0] = -6.624269, states[40]= 0.003065
Saving checkpoint... 
Iteration: 1871638028, states[0] = -57.773184, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1884854973, states[0] = -94.999318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898291931, states[0] = -94.957953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912024691, states[0] = 20.092017, states[40]= 0.007080
Saving checkpoint... 
Iteration: 1925566379, states[0] = 4.791761, states[40]= 0.004704
Saving checkpoint... 
Iteration: 1938906465, states[0] = -95.013360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947452501, states[0] = -95.023583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960828247, states[0] = -94.980436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969915736, states[0] = -95.015151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980363729, states[0] = -94.997833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993839128, states[0] = -94.986120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006998544, states[0] = -95.029638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017685045, states[0] = -94.792992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031141535, states[0] = -61.148105, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2044578467, states[0] = -1.536803, states[40]= 0.004030
Saving checkpoint... 
Iteration: 2057785214, states[0] = -94.948245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071161499, states[0] = -90.576961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084775948, states[0] = -94.939432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098076472, states[0] = -0.350473, states[40]= 0.004205
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.905482
 - CaMKt in component CaMK (millimolar): 0.007094
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.600370
 - nass in component intracellular_ions (millimolar): 6.600430
 - ki in component intracellular_ions (millimolar): 145.375190
 - kss in component intracellular_ions (millimolar): 145.375171
 - cansr in component intracellular_ions (millimolar): 1.319896
 - cajsr in component intracellular_ions (millimolar): 1.281759
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880064
 - hs in component INa (dimensionless): 0.880059
 - j in component INa (dimensionless): 0.880030
 - hsp in component INa (dimensionless): 0.725949
 - jp in component INa (dimensionless): 0.880011
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709947
 - hLp in component INaL (dimensionless): 0.451929
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620863
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695720
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935185
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001633
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330988
 - xs1 in component IKs (dimensionless): 0.242040
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:58:33 (464988): called boinc_finish(0)

</stderr_txt>
]]>


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