𝕏

Task 55986837

Name HuVeMOp_20240703230118663892_ORdGradInc_k_26-Pueyo_APDR-conf_229_1
Workunit 26588133
Created 3 Jul 2024, 21:01:27 UTC
Sent 3 Jul 2024, 22:53:27 UTC
Report deadline 7 Jul 2024, 8:29:27 UTC
Received 4 Jul 2024, 4:25:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233905
Run time 3 hours 0 min 1 sec
CPU time 2 hours 55 min 29 sec
Validate state Valid
Credit 67.83
Device peak FLOPS 2.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.04 MB
Peak swap size 6.23 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230118663892_ORdGradInc_k_26-Pueyo_APDR-conf_229.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230118663892_ORdGradInc_k_26-Pueyo_APDR-conf_229_1_r2112169811_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230118663892_ORdGradInc_k_26-Pueyo_APDR-conf_229_1_r2112169811_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.329073
     * GNaL_b in INaL: 0.005559
     * Gto_b in Ito: 0.082354
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032006
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.166117
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.481568
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029249
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10670533, states[0] = -94.861913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21861339, states[0] = -95.066988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32659196, states[0] = -92.726664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44321338, states[0] = -95.015154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54718815, states[0] = -94.896490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64628690, states[0] = -49.924937, states[40]= 0.000028
Saving checkpoint... 
Iteration: 75401622, states[0] = -95.032388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86512443, states[0] = 22.672292, states[40]= 0.030161
Saving checkpoint... 
Iteration: 96926717, states[0] = -95.033649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108026496, states[0] = 19.682293, states[40]= 0.006719
Saving checkpoint... 
Iteration: 118825265, states[0] = -94.992094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130372589, states[0] = -95.013885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142076261, states[0] = -0.835613, states[40]= 0.004162
Saving checkpoint... 
Iteration: 152476935, states[0] = -95.038131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161497011, states[0] = -95.040483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172809140, states[0] = -94.979194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184055956, states[0] = 9.059736, states[40]= 0.004926
Saving checkpoint... 
Iteration: 195845869, states[0] = -95.000454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206137030, states[0] = -58.025268, states[40]= 0.000007
Saving checkpoint... 
Iteration: 217091911, states[0] = -12.764934, states[40]= 0.001824
Saving checkpoint... 
Iteration: 227599816, states[0] = -20.252735, states[40]= 0.000953
Saving checkpoint... 
Iteration: 238141329, states[0] = -63.065457, states[40]= 0.000003
Saving checkpoint... 
Iteration: 248465852, states[0] = -95.035330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258751601, states[0] = -94.923969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269190153, states[0] = -94.819327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279299626, states[0] = -94.971540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291383639, states[0] = -95.015611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303047135, states[0] = 12.606910, states[40]= 0.005059
Saving checkpoint... 
Iteration: 313229198, states[0] = -94.892353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323640437, states[0] = -61.980094, states[40]= 0.000004
Saving checkpoint... 
Iteration: 334805154, states[0] = -94.975620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346858892, states[0] = -95.006031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358307237, states[0] = -94.977104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369613891, states[0] = -33.751719, states[40]= 0.000305
Saving checkpoint... 
Iteration: 382561490, states[0] = 6.695173, states[40]= 0.004837
Saving checkpoint... 
Iteration: 395985595, states[0] = -95.038034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409315201, states[0] = -94.982531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422674816, states[0] = -94.746130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436044612, states[0] = 13.577969, states[40]= 0.005118
Saving checkpoint... 
Iteration: 449190048, states[0] = -94.818939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462760234, states[0] = -94.934149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476099270, states[0] = -19.722603, states[40]= 0.000990
Saving checkpoint... 
Iteration: 489311527, states[0] = -94.980012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502539323, states[0] = 15.551442, states[40]= 0.005312
Saving checkpoint... 
Iteration: 515219346, states[0] = -94.875987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527471245, states[0] = -95.035918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540754443, states[0] = -94.927248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554250722, states[0] = -94.922618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567695889, states[0] = -94.831321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580959403, states[0] = -95.033989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594321122, states[0] = -94.986202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607465106, states[0] = -95.034910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620880406, states[0] = -95.014255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634150672, states[0] = -76.201752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647541343, states[0] = 14.809508, states[40]= 0.005224
Saving checkpoint... 
Iteration: 660899240, states[0] = -95.020315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674271294, states[0] = -94.946017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687511853, states[0] = 22.854238, states[40]= 0.034334
Saving checkpoint... 
Iteration: 700664110, states[0] = -93.571610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713757840, states[0] = -94.931203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726965932, states[0] = -95.034965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740262865, states[0] = -94.936949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753510635, states[0] = 23.159254, states[40]= 0.045213
Saving checkpoint... 
Iteration: 766770138, states[0] = -94.944765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779901815, states[0] = -95.020990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793371820, states[0] = -95.010992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806684648, states[0] = -94.805775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819859142, states[0] = -95.005828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833040044, states[0] = 15.288571, states[40]= 0.005278
Saving checkpoint... 
Iteration: 846478481, states[0] = -95.036770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859969296, states[0] = -95.035405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873366433, states[0] = -95.008829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886862701, states[0] = -95.007292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900012239, states[0] = 22.771696, states[40]= 0.031566
Saving checkpoint... 
Iteration: 913318476, states[0] = -94.984327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925566304, states[0] = 4.486370, states[40]= 0.004715
Saving checkpoint... 
Iteration: 939067174, states[0] = 4.068692, states[40]= 0.004686
Saving checkpoint... 
Iteration: 952454938, states[0] = -95.032978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965519745, states[0] = 21.372756, states[40]= 0.009907
Saving checkpoint... 
Iteration: 978946973, states[0] = -95.031504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992096714, states[0] = -17.278143, states[40]= 0.001201
Saving checkpoint... 
Iteration: 1005353624, states[0] = -95.003267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018758376, states[0] = -94.931633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032252176, states[0] = -94.924134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045636618, states[0] = -57.536356, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1059105978, states[0] = -26.138161, states[40]= 0.000651
Saving checkpoint... 
Iteration: 1072429356, states[0] = -95.027812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085632592, states[0] = -53.041556, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1098972566, states[0] = -95.035747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112251221, states[0] = -94.922885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125737288, states[0] = -94.904028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139053645, states[0] = 10.020418, states[40]= 0.004957
Saving checkpoint... 
Iteration: 1152315476, states[0] = -94.982229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165688817, states[0] = -94.815714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179134897, states[0] = -55.597760, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1192509708, states[0] = 23.463860, states[40]= 0.056143
Saving checkpoint... 
Iteration: 1205768308, states[0] = -94.942563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218880482, states[0] = -95.013895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232294537, states[0] = -94.966876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245736538, states[0] = -94.902858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258924798, states[0] = -95.026651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272090980, states[0] = -11.902798, states[40]= 0.001978
Saving checkpoint... 
Iteration: 1285423836, states[0] = -95.026409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298526912, states[0] = 19.613770, states[40]= 0.006634
Saving checkpoint... 
Iteration: 1311929171, states[0] = -95.027616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323820513, states[0] = -94.985348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337017089, states[0] = 21.891419, states[40]= 0.013358
Saving checkpoint... 
Iteration: 1350249282, states[0] = -94.920264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363596331, states[0] = -16.912613, states[40]= 0.001240
Saving checkpoint... 
Iteration: 1377018475, states[0] = 21.629029, states[40]= 0.011267
Saving checkpoint... 
Iteration: 1390474165, states[0] = -95.035795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403853214, states[0] = -95.002822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417373268, states[0] = -95.011137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430662830, states[0] = -93.013849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443993941, states[0] = -95.038415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457337881, states[0] = -94.995257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470482877, states[0] = -95.036974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483798764, states[0] = -94.970064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496985933, states[0] = -95.037366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510247284, states[0] = 9.669016, states[40]= 0.005691
Saving checkpoint... 
Iteration: 1523524972, states[0] = -67.662550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1536813898, states[0] = -95.201299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550042471, states[0] = -95.248056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563474300, states[0] = -95.135157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576664793, states[0] = -95.113944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590017482, states[0] = 21.725664, states[40]= 0.014211
Saving checkpoint... 
Iteration: 1603065737, states[0] = -95.120198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616173530, states[0] = -9.792158, states[40]= 0.002704
Saving checkpoint... 
Iteration: 1629366970, states[0] = -3.769154, states[40]= 0.004120
Saving checkpoint... 
Iteration: 1642330478, states[0] = -80.271695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655481667, states[0] = -18.620123, states[40]= 0.001184
Saving checkpoint... 
Iteration: 1668984283, states[0] = -21.527742, states[40]= 0.000928
Saving checkpoint... 
Iteration: 1682063757, states[0] = -95.284511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695183237, states[0] = -95.165370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708493675, states[0] = -95.308138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721809347, states[0] = -49.940916, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1734785453, states[0] = -95.170301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748119568, states[0] = 21.045835, states[40]= 0.011449
Saving checkpoint... 
Iteration: 1761168450, states[0] = -95.129967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774490287, states[0] = -95.305853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787831575, states[0] = -82.427010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801095212, states[0] = -20.306296, states[40]= 0.001000
Saving checkpoint... 
Iteration: 1814226122, states[0] = -94.927798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827363854, states[0] = -95.037179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840384958, states[0] = -95.035618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853501474, states[0] = 47.936164, states[40]= 0.062459
Saving checkpoint... 
Iteration: 1866501735, states[0] = 46.437602, states[40]= 0.078613
Saving checkpoint... 
Iteration: 1879948105, states[0] = -95.037477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893377032, states[0] = -95.016479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906556158, states[0] = 8.927389, states[40]= 0.004924
Saving checkpoint... 
Iteration: 1919736098, states[0] = -94.903748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932977661, states[0] = -95.037237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946148931, states[0] = -73.511964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1959331710, states[0] = -94.992138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972652697, states[0] = -79.720638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985876053, states[0] = -95.012034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999035536, states[0] = 16.890761, states[40]= 0.005539
Saving checkpoint... 
Iteration: 2012336225, states[0] = -94.994090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025655797, states[0] = -85.112922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038957911, states[0] = -95.032795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052306571, states[0] = -94.975509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065405983, states[0] = -95.021308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078722243, states[0] = -94.879857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092114854, states[0] = -34.687048, states[40]= 0.000271
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.914539
 - CaMKt in component CaMK (millimolar): 0.006997
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573945
 - nass in component intracellular_ions (millimolar): 6.574005
 - ki in component intracellular_ions (millimolar): 145.402745
 - kss in component intracellular_ions (millimolar): 145.402725
 - cansr in component intracellular_ions (millimolar): 1.315547
 - cajsr in component intracellular_ions (millimolar): 1.277674
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880221
 - hs in component INa (dimensionless): 0.880216
 - j in component INa (dimensionless): 0.880187
 - hsp in component INa (dimensionless): 0.726245
 - jp in component INa (dimensionless): 0.880168
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710610
 - hLp in component INaL (dimensionless): 0.453468
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622751
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697908
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935851
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001619
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329318
 - xs1 in component IKs (dimensionless): 0.239580
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:25:31 (4420): called boinc_finish(0)

</stderr_txt>
]]>


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