𝕏

Task 55985878

Name HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_53_0
Workunit 26587656
Created 3 Jul 2024, 21:00:56 UTC
Sent 3 Jul 2024, 22:39:40 UTC
Report deadline 7 Jul 2024, 8:15:40 UTC
Received 4 Jul 2024, 4:10:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233905
Run time 3 hours 2 min 29 sec
CPU time 2 hours 57 min 8 sec
Validate state Valid
Credit 63.31
Device peak FLOPS 2.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.04 MB
Peak swap size 6.21 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_53.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_53_0_r1477546547_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_53_0_r1477546547_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.896288
     * GNaL_b in INaL: 0.005864
     * Gto_b in Ito: 0.082071
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032307
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.165334
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.996559
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032084
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10122843, states[0] = -49.160010, states[40]= 0.000029
Saving checkpoint... 
Iteration: 19966662, states[0] = -95.107332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29898451, states[0] = -95.073614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40094579, states[0] = -17.409474, states[40]= 0.001192
Saving checkpoint... 
Iteration: 51524692, states[0] = 19.918999, states[40]= 0.007336
Saving checkpoint... 
Iteration: 63020943, states[0] = 20.928320, states[40]= 0.009149
Saving checkpoint... 
Iteration: 73348605, states[0] = -95.020430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85018438, states[0] = 21.546452, states[40]= 0.011592
Saving checkpoint... 
Iteration: 96027353, states[0] = 19.362696, states[40]= 0.006672
Saving checkpoint... 
Iteration: 107767271, states[0] = -94.954340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119746341, states[0] = -94.928508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130664781, states[0] = -94.023503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141419903, states[0] = -95.034179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153530375, states[0] = 18.508413, states[40]= 0.006160
Saving checkpoint... 
Iteration: 163825471, states[0] = -94.996960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175098946, states[0] = -19.774045, states[40]= 0.000983
Saving checkpoint... 
Iteration: 186199198, states[0] = -94.848233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197821308, states[0] = -94.993924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208576348, states[0] = -1.031408, states[40]= 0.004132
Saving checkpoint... 
Iteration: 219082257, states[0] = -4.954927, states[40]= 0.003425
Saving checkpoint... 
Iteration: 229607472, states[0] = -27.930855, states[40]= 0.000558
Saving checkpoint... 
Iteration: 240623781, states[0] = -44.097675, states[40]= 0.000069
Saving checkpoint... 
Iteration: 251886650, states[0] = -95.023234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263267671, states[0] = -94.950316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274464293, states[0] = -95.041245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285549487, states[0] = 11.571124, states[40]= 0.005044
Saving checkpoint... 
Iteration: 297546096, states[0] = 12.900909, states[40]= 0.005118
Saving checkpoint... 
Iteration: 309590607, states[0] = -11.855358, states[40]= 0.001986
Saving checkpoint... 
Iteration: 319849758, states[0] = -95.008722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331372889, states[0] = -95.018330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342330721, states[0] = -94.999024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350203956, states[0] = -94.857031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360525108, states[0] = 20.058223, states[40]= 0.007249
Saving checkpoint... 
Iteration: 371210097, states[0] = -94.868584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382652299, states[0] = -80.164548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393972969, states[0] = -95.042462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405517737, states[0] = 21.762571, states[40]= 0.012629
Saving checkpoint... 
Iteration: 417567549, states[0] = 3.732336, states[40]= 0.004667
Saving checkpoint... 
Iteration: 427897505, states[0] = -95.026437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439779023, states[0] = -94.961380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451763427, states[0] = -94.945616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462654461, states[0] = -83.979123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474423063, states[0] = -95.033122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486211894, states[0] = -94.871790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497622180, states[0] = -42.425250, states[40]= 0.000089
Saving checkpoint... 
Iteration: 508755890, states[0] = -94.937016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519575005, states[0] = -0.228174, states[40]= 0.004247
Saving checkpoint... 
Iteration: 531585044, states[0] = -7.078086, states[40]= 0.002974
Saving checkpoint... 
Iteration: 542626336, states[0] = -46.800339, states[40]= 0.000046
Saving checkpoint... 
Iteration: 554511652, states[0] = 22.957065, states[40]= 0.036547
Saving checkpoint... 
Iteration: 567302604, states[0] = -94.980851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580766478, states[0] = -94.948820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594176257, states[0] = -94.778856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607318881, states[0] = -94.991868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620505414, states[0] = 27.913074, states[40]= 0.138049
Saving checkpoint... 
Iteration: 633935691, states[0] = -95.035797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647173164, states[0] = -94.736990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660353166, states[0] = -95.010058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673841854, states[0] = -95.004692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687137727, states[0] = -59.504130, states[40]= 0.000006
Saving checkpoint... 
Iteration: 700406090, states[0] = -95.028705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712628534, states[0] = -49.175408, states[40]= 0.000031
Saving checkpoint... 
Iteration: 725861539, states[0] = -95.013627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739305462, states[0] = -94.982816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752686948, states[0] = -94.821623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766085221, states[0] = -7.219621, states[40]= 0.002943
Saving checkpoint... 
Iteration: 779239640, states[0] = -94.915977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792413419, states[0] = -95.030579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805696407, states[0] = -94.841794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819085784, states[0] = -7.675088, states[40]= 0.002844
Saving checkpoint... 
Iteration: 832364206, states[0] = -95.014652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845696589, states[0] = -94.842139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859068770, states[0] = 3.127517, states[40]= 0.004618
Saving checkpoint... 
Iteration: 872312714, states[0] = -94.987730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885879750, states[0] = -95.020455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899304299, states[0] = -94.981882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912470662, states[0] = -95.041803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925547620, states[0] = 12.307529, states[40]= 0.005082
Saving checkpoint... 
Iteration: 938903428, states[0] = -95.027825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952323076, states[0] = -94.994226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965682113, states[0] = -94.808748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978841668, states[0] = -95.004412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992355704, states[0] = -95.010979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005778409, states[0] = -94.960458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019112041, states[0] = -32.335242, states[40]= 0.000356
Saving checkpoint... 
Iteration: 1032608463, states[0] = -28.877236, states[40]= 0.000513
Saving checkpoint... 
Iteration: 1045879704, states[0] = -95.020341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059057614, states[0] = 8.240412, states[40]= 0.004914
Saving checkpoint... 
Iteration: 1072438581, states[0] = -95.036119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085699691, states[0] = -94.848223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098607393, states[0] = -27.847094, states[40]= 0.000562
Saving checkpoint... 
Iteration: 1109676394, states[0] = -94.779718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122942755, states[0] = -95.036912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136400982, states[0] = -95.027013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149796814, states[0] = -94.976115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163151444, states[0] = -78.665933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176549526, states[0] = 11.556226, states[40]= 0.005043
Saving checkpoint... 
Iteration: 1190022624, states[0] = 20.693567, states[40]= 0.008211
Saving checkpoint... 
Iteration: 1203271553, states[0] = -94.953677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216502725, states[0] = 39.575728, states[40]= 0.120509
Saving checkpoint... 
Iteration: 1229846328, states[0] = -95.006540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243013379, states[0] = 22.583572, states[40]= 0.025473
Saving checkpoint... 
Iteration: 1256475321, states[0] = -95.042273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269905992, states[0] = -95.028330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283400546, states[0] = -95.026798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296907555, states[0] = -95.028736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310334059, states[0] = -95.000255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323503522, states[0] = 34.610997, states[40]= 0.144360
Saving checkpoint... 
Iteration: 1336637728, states[0] = -59.504685, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1349860861, states[0] = -95.012963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363268290, states[0] = -94.950241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376646254, states[0] = -70.407550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390017403, states[0] = 21.827800, states[40]= 0.013172
Saving checkpoint... 
Iteration: 1403412815, states[0] = -95.030051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416679144, states[0] = -94.797075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429778132, states[0] = -94.959937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442914413, states[0] = -95.030433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456247646, states[0] = -94.926276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469629232, states[0] = -49.936753, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1482551249, states[0] = 10.868242, states[40]= 0.005013
Saving checkpoint... 
Iteration: 1496006831, states[0] = 25.583849, states[40]= 0.108084
Saving checkpoint... 
Iteration: 1508739162, states[0] = 13.587595, states[40]= 0.006187
Saving checkpoint... 
Iteration: 1522005910, states[0] = -43.998514, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1535351466, states[0] = -95.258806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548586274, states[0] = -95.296964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561699513, states[0] = -95.199464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574738739, states[0] = 13.123020, states[40]= 0.006234
Saving checkpoint... 
Iteration: 1587901966, states[0] = 46.039885, states[40]= 0.066819
Saving checkpoint... 
Iteration: 1601124182, states[0] = 19.424243, states[40]= 0.008726
Saving checkpoint... 
Iteration: 1614340665, states[0] = 12.101841, states[40]= 0.006098
Saving checkpoint... 
Iteration: 1627461152, states[0] = -95.290709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640434003, states[0] = 15.285081, states[40]= 0.006665
Saving checkpoint... 
Iteration: 1653485018, states[0] = -95.180377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666831347, states[0] = 16.473175, states[40]= 0.007002
Saving checkpoint... 
Iteration: 1680097598, states[0] = -36.657209, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1693324221, states[0] = -70.432827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1706634876, states[0] = -95.263408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720000976, states[0] = -40.498130, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1733367417, states[0] = -95.297416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746719436, states[0] = -63.447847, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1760000962, states[0] = -95.212266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773230680, states[0] = -95.258099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786477396, states[0] = -95.305636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799809133, states[0] = -50.220579, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1813059121, states[0] = 6.611324, states[40]= 0.004910
Saving checkpoint... 
Iteration: 1826156221, states[0] = -90.199838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839441589, states[0] = -95.057691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852463064, states[0] = -95.054599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865455957, states[0] = -95.048727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878743680, states[0] = -94.927585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892232181, states[0] = -94.909034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904820573, states[0] = -94.995171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917317375, states[0] = -94.992208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930560359, states[0] = 7.024520, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1944052254, states[0] = 10.445225, states[40]= 0.004997
Saving checkpoint... 
Iteration: 1957216156, states[0] = -94.879085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970403007, states[0] = -95.027468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983646954, states[0] = -71.462300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1997003720, states[0] = 33.609676, states[40]= 0.147564
Saving checkpoint... 
Iteration: 2010434776, states[0] = -95.034849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023763438, states[0] = -94.944703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036918485, states[0] = -95.031087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050167468, states[0] = -94.436720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063259263, states[0] = -94.939952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076372429, states[0] = -95.017051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089609736, states[0] = -30.105056, states[40]= 0.000455
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.920735
 - CaMKt in component CaMK (millimolar): 0.006883
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.565184
 - nass in component intracellular_ions (millimolar): 6.565244
 - ki in component intracellular_ions (millimolar): 145.413434
 - kss in component intracellular_ions (millimolar): 145.413414
 - cansr in component intracellular_ions (millimolar): 1.308313
 - cajsr in component intracellular_ions (millimolar): 1.270604
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880328
 - hs in component INa (dimensionless): 0.880324
 - j in component INa (dimensionless): 0.880295
 - hsp in component INa (dimensionless): 0.726448
 - jp in component INa (dimensionless): 0.880277
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710933
 - hLp in component INaL (dimensionless): 0.454130
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623385
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698643
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936163
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331139
 - xs1 in component IKs (dimensionless): 0.238810
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:10:02 (232): called boinc_finish(0)

</stderr_txt>
]]>