𝕏

Task 55985523

Name HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304_1
Workunit 26587478
Created 3 Jul 2024, 21:00:46 UTC
Sent 3 Jul 2024, 22:36:14 UTC
Report deadline 7 Jul 2024, 8:12:14 UTC
Received 6 Jul 2024, 13:03:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231095
Run time 1 hours 15 min 19 sec
CPU time 1 hours 7 min 22 sec
Validate state Valid
Credit 60.45
Device peak FLOPS 4.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.64 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304_1_r1866726359_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304_1_r1866726359_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.821517
     * GNaL_b in INaL: 0.005819
     * Gto_b in Ito: 0.084363
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031322
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.162754
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.899235
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033999
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5882315, states[0] = -95.118532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16427935, states[0] = -95.088849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26822608, states[0] = -95.023996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37069826, states[0] = 2.449896, states[40]= 0.004539
Saving checkpoint... 
Iteration: 51892870, states[0] = -95.025699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65771349, states[0] = -94.943883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80606738, states[0] = -25.453789, states[40]= 0.000693
Saving checkpoint... 
Iteration: 96076253, states[0] = -0.167155, states[40]= 0.004221
Saving checkpoint... 
Iteration: 110554422, states[0] = 9.994125, states[40]= 0.004909
Saving checkpoint... 
Iteration: 125125435, states[0] = -42.880694, states[40]= 0.000086
Saving checkpoint... 
Iteration: 139675511, states[0] = -94.671348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153931231, states[0] = -95.013065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168254185, states[0] = -94.908957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179663120, states[0] = -90.728895, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304_1_r1866726359_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703230042490724_ORdGradInc_k_26-Pueyo_APDR-conf_304_1_r1866726359_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.821517
     * GNaL_b in INaL: 0.005819
     * Gto_b in Ito: 0.084363
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031322
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.162754
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.899235
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033999
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 179663120
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.728895 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 193703769, states[0] = -94.827355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200218273, states[0] = -94.854549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203782855, states[0] = -94.939462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217540676, states[0] = 15.264681, states[40]= 0.005198
Saving checkpoint... 
Iteration: 222953032, states[0] = -95.016418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233168408, states[0] = -93.834795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247067395, states[0] = 4.530326, states[40]= 0.004676
Saving checkpoint... 
Iteration: 261138506, states[0] = -56.507754, states[40]= 0.000009
Saving checkpoint... 
Iteration: 275022854, states[0] = 20.696766, states[40]= 0.007835
Saving checkpoint... 
Iteration: 288505048, states[0] = 28.219814, states[40]= 0.147495
Saving checkpoint... 
Iteration: 297621810, states[0] = -39.113204, states[40]= 0.000149
Saving checkpoint... 
Iteration: 311874144, states[0] = -94.995000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324745505, states[0] = -94.896756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338758349, states[0] = -94.913171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350674377, states[0] = -94.619106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362222086, states[0] = -94.860783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376819826, states[0] = -94.967824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386446545, states[0] = -95.014944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400256621, states[0] = -94.911040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413403233, states[0] = -95.004608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427225103, states[0] = -94.865834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441582970, states[0] = -4.154382, states[40]= 0.003552
Saving checkpoint... 
Iteration: 456479179, states[0] = -95.020336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470868940, states[0] = -94.992856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480794253, states[0] = -94.949037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494991083, states[0] = -95.021913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505318061, states[0] = -94.966595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519606046, states[0] = -24.229492, states[40]= 0.000750
Saving checkpoint... 
Iteration: 533829482, states[0] = -94.973642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548154133, states[0] = -76.734626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562721940, states[0] = -94.860400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571073251, states[0] = 1.649849, states[40]= 0.004432
Saving checkpoint... 
Iteration: 575522250, states[0] = 20.833622, states[40]= 0.008124
Saving checkpoint... 
Iteration: 589332274, states[0] = -94.975216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603526796, states[0] = 19.712906, states[40]= 0.006597
Saving checkpoint... 
Iteration: 617614669, states[0] = -32.289345, states[40]= 0.000369
Saving checkpoint... 
Iteration: 627601685, states[0] = -20.168496, states[40]= 0.000961
Saving checkpoint... 
Iteration: 639874183, states[0] = -94.994792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653994764, states[0] = -95.022270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668091755, states[0] = -11.063298, states[40]= 0.002115
Saving checkpoint... 
Iteration: 677797764, states[0] = -94.951772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691783702, states[0] = -94.939661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705896034, states[0] = -95.002262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715583470, states[0] = -4.501447, states[40]= 0.003483
Saving checkpoint... 
Iteration: 720572278, states[0] = 2.152989, states[40]= 0.004483
Saving checkpoint... 
Iteration: 722259153, states[0] = -94.913875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729851260, states[0] = -94.984989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744611575, states[0] = -29.385730, states[40]= 0.000504
Saving checkpoint... 
Iteration: 760063918, states[0] = 6.107428, states[40]= 0.004765
Saving checkpoint... 
Iteration: 776096031, states[0] = -14.913824, states[40]= 0.001474
Saving checkpoint... 
Iteration: 791597088, states[0] = -15.889584, states[40]= 0.001348
Saving checkpoint... 
Iteration: 792808960, states[0] = -94.960179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795195227, states[0] = -94.809074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808707336, states[0] = -94.833575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823312237, states[0] = -94.962467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837897799, states[0] = -95.002718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847667164, states[0] = -93.417128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861573729, states[0] = 1.398677, states[40]= 0.004405
Saving checkpoint... 
Iteration: 867920752, states[0] = -95.008993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883177979, states[0] = -94.725372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898071833, states[0] = 2.379565, states[40]= 0.004505
Saving checkpoint... 
Iteration: 912696115, states[0] = -94.810884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919746483, states[0] = -94.897689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936399800, states[0] = -95.003259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952608010, states[0] = -26.057824, states[40]= 0.000666
Saving checkpoint... 
Iteration: 963214021, states[0] = -94.846079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980217683, states[0] = -94.852689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996831151, states[0] = -94.974310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009118029, states[0] = -35.470115, states[40]= 0.000248
Saving checkpoint... 
Iteration: 1025710589, states[0] = -94.839649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042378567, states[0] = -94.996165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059114527, states[0] = -32.155399, states[40]= 0.000375
Saving checkpoint... 
Iteration: 1075493731, states[0] = -95.021871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092076541, states[0] = -0.140317, states[40]= 0.004219
Saving checkpoint... 
Iteration: 1108734679, states[0] = -94.880637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125342642, states[0] = -94.980480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142076798, states[0] = -0.286631, states[40]= 0.004199
Saving checkpoint... 
Iteration: 1158569247, states[0] = 3.655838, states[40]= 0.004613
Saving checkpoint... 
Iteration: 1175203445, states[0] = -94.825705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191902058, states[0] = -95.003762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207975065, states[0] = -95.019253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224486941, states[0] = -95.020905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240841625, states[0] = -94.979879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257219745, states[0] = -94.856147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273451002, states[0] = -95.015214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289848934, states[0] = -94.983513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306169595, states[0] = -94.111606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322550305, states[0] = 11.679477, states[40]= 0.004960
Saving checkpoint... 
Iteration: 1333684860, states[0] = -94.781659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350030605, states[0] = 18.623574, states[40]= 0.005961
Saving checkpoint... 
Iteration: 1366522242, states[0] = 20.835554, states[40]= 0.008128
Saving checkpoint... 
Iteration: 1382991089, states[0] = -95.021340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399222884, states[0] = -94.861467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415560901, states[0] = 7.412769, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1432423948, states[0] = -95.009403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448887025, states[0] = -94.998870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465259908, states[0] = -94.914285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481654947, states[0] = -78.083702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498566045, states[0] = 5.154105, states[40]= 0.004714
Saving checkpoint... 
Iteration: 1515192123, states[0] = -95.129619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531903387, states[0] = -39.194196, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1543370523, states[0] = -95.103352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559897169, states[0] = -95.171222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576369416, states[0] = -95.112785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592751335, states[0] = 7.008367, states[40]= 0.005521
Saving checkpoint... 
Iteration: 1608756991, states[0] = -95.066131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625039671, states[0] = -95.247425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641520642, states[0] = -95.222071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657659928, states[0] = -95.087236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673710583, states[0] = 23.674578, states[40]= 0.046540
Saving checkpoint... 
Iteration: 1689955119, states[0] = 4.821393, states[40]= 0.005346
Saving checkpoint... 
Iteration: 1706026932, states[0] = -95.231877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722226058, states[0] = -95.230666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738315126, states[0] = -54.552890, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1754705418, states[0] = 28.590349, states[40]= 0.125395
Saving checkpoint... 
Iteration: 1770904909, states[0] = 29.845565, states[40]= 0.130833
Saving checkpoint... 
Iteration: 1787082723, states[0] = -95.290515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803063446, states[0] = 4.890657, states[40]= 0.004841
Saving checkpoint... 
Iteration: 1819486379, states[0] = -95.059269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835749992, states[0] = -94.926471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851794693, states[0] = -94.963823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868200489, states[0] = -94.828800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884639864, states[0] = -58.465042, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1901023778, states[0] = 20.445017, states[40]= 0.007449
Saving checkpoint... 
Iteration: 1917453899, states[0] = -95.017454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933465535, states[0] = -95.018614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950470766, states[0] = -95.018893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967088411, states[0] = -8.261390, states[40]= 0.002691
Saving checkpoint... 
Iteration: 1983975160, states[0] = -95.019018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000443065, states[0] = -95.013349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016881787, states[0] = -94.996753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033613068, states[0] = -30.788061, states[40]= 0.000437
Saving checkpoint... 
Iteration: 2049945325, states[0] = -95.013618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066526187, states[0] = 19.875107, states[40]= 0.006737
Saving checkpoint... 
Iteration: 2083223614, states[0] = -94.862218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099831528, states[0] = -94.973766, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.897792
 - CaMKt in component CaMK (millimolar): 0.007017
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559803
 - nass in component intracellular_ions (millimolar): 6.559863
 - ki in component intracellular_ions (millimolar): 145.417365
 - kss in component intracellular_ions (millimolar): 145.417346
 - cansr in component intracellular_ions (millimolar): 1.313450
 - cajsr in component intracellular_ions (millimolar): 1.275308
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879930
 - hs in component INa (dimensionless): 0.879926
 - j in component INa (dimensionless): 0.879897
 - hsp in component INa (dimensionless): 0.725697
 - jp in component INa (dimensionless): 0.879877
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709418
 - hLp in component INaL (dimensionless): 0.450707
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619686
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694263
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934524
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001608
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332056
 - xs1 in component IKs (dimensionless): 0.243341
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:03:45 (15860): called boinc_finish(0)

</stderr_txt>
]]>


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