𝕏

Task 55983519

Name HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_771_0
Workunit 26586513
Created 3 Jul 2024, 20:41:10 UTC
Sent 3 Jul 2024, 22:19:55 UTC
Report deadline 7 Jul 2024, 7:55:55 UTC
Received 5 Jul 2024, 23:56:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217971
Run time 1 hours 18 min 26 sec
CPU time 52 min 12 sec
Validate state Valid
Credit 60.40
Device peak FLOPS 5.38 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 5.27 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_771.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_771_0_r814095573_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_771_0_r814095573_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.266979
     * GNaL_b in INaL: 0.006033
     * Gto_b in Ito: 0.086571
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031993
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.159715
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.214195
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032828
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12105314, states[0] = -27.449678, states[40]= 0.000563
Saving checkpoint... 
Iteration: 24226804, states[0] = -94.914717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36152518, states[0] = -78.469471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48351279, states[0] = -95.003016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60522506, states[0] = 20.531775, states[40]= 0.007765
Saving checkpoint... 
Iteration: 73106699, states[0] = -25.509730, states[40]= 0.000690
Saving checkpoint... 
Iteration: 85160252, states[0] = -88.040983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97610824, states[0] = -29.057291, states[40]= 0.000521
Saving checkpoint... 
Iteration: 109569875, states[0] = 3.320221, states[40]= 0.004577
Saving checkpoint... 
Iteration: 121927272, states[0] = -95.007810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134017630, states[0] = 21.594921, states[40]= 0.012115
Saving checkpoint... 
Iteration: 146235608, states[0] = -94.874528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158045040, states[0] = 13.689155, states[40]= 0.005004
Saving checkpoint... 
Iteration: 170047132, states[0] = 12.915605, states[40]= 0.004963
Saving checkpoint... 
Iteration: 182112435, states[0] = -30.285350, states[40]= 0.000463
Saving checkpoint... 
Iteration: 194484177, states[0] = -95.015850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206674648, states[0] = -94.614785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219131786, states[0] = -49.494511, states[40]= 0.000031
Saving checkpoint... 
Iteration: 231289616, states[0] = -94.937631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243687088, states[0] = -94.777583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255653721, states[0] = -76.436956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268007935, states[0] = 23.829267, states[40]= 0.085673
Saving checkpoint... 
Iteration: 280226513, states[0] = -94.858374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292203614, states[0] = -94.815537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303544080, states[0] = 14.056216, states[40]= 0.005026
Saving checkpoint... 
Iteration: 315799169, states[0] = -94.945610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327774459, states[0] = -94.922810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339923528, states[0] = -95.004044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349506330, states[0] = 25.382627, states[40]= 0.121922
Saving checkpoint... 
Iteration: 360370078, states[0] = -94.986967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371302920, states[0] = -94.948552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382511160, states[0] = 22.619633, states[40]= 0.039849
Saving checkpoint... 
Iteration: 393440328, states[0] = -95.007829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404622271, states[0] = -39.694012, states[40]= 0.000138
Saving checkpoint... 
Iteration: 415319169, states[0] = -94.960245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426755581, states[0] = -94.901006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437578651, states[0] = -1.319520, states[40]= 0.004043
Saving checkpoint... 
Iteration: 448630089, states[0] = -47.681689, states[40]= 0.000041
Saving checkpoint... 
Iteration: 459289339, states[0] = -94.937115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470376708, states[0] = -94.989501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481571428, states[0] = 2.645010, states[40]= 0.004517
Saving checkpoint... 
Iteration: 492900584, states[0] = -94.997642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503650573, states[0] = -71.635882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514885387, states[0] = -94.992650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525607360, states[0] = -25.494913, states[40]= 0.000692
Saving checkpoint... 
Iteration: 536739988, states[0] = -94.879536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547503367, states[0] = 34.318325, states[40]= 0.153033
Saving checkpoint... 
Iteration: 558555509, states[0] = 9.690641, states[40]= 0.004864
Saving checkpoint... 
Iteration: 569640257, states[0] = -58.758229, states[40]= 0.000007
Saving checkpoint... 
Iteration: 580278956, states[0] = -94.927217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590811405, states[0] = -94.954760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601981599, states[0] = -95.014885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612503950, states[0] = 31.451823, states[40]= 0.160456
Saving checkpoint... 
Iteration: 623571192, states[0] = 2.763458, states[40]= 0.004528
Saving checkpoint... 
Iteration: 634386294, states[0] = -94.992886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645835066, states[0] = -94.969873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656572213, states[0] = 2.246922, states[40]= 0.004481
Saving checkpoint... 
Iteration: 667822504, states[0] = -94.962255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678738490, states[0] = -94.877201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689822856, states[0] = -94.962466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700888897, states[0] = -94.993737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712426288, states[0] = -95.004458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723313800, states[0] = -94.956370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734696500, states[0] = -94.800276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745710016, states[0] = -94.827989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757116103, states[0] = -33.729978, states[40]= 0.000312
Saving checkpoint... 
Iteration: 767964232, states[0] = -95.012080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779091081, states[0] = -10.451953, states[40]= 0.002234
Saving checkpoint... 
Iteration: 789757885, states[0] = -94.903642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801113605, states[0] = -31.362024, states[40]= 0.000413
Saving checkpoint... 
Iteration: 811606848, states[0] = -25.015677, states[40]= 0.000714
Saving checkpoint... 
Iteration: 822996180, states[0] = -95.016677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833805559, states[0] = -94.950272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845149505, states[0] = -70.128882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856151755, states[0] = -73.371522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867623830, states[0] = -41.242635, states[40]= 0.000110
Saving checkpoint... 
Iteration: 878330837, states[0] = -94.967259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889817424, states[0] = -94.958753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900192479, states[0] = -94.791172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911467912, states[0] = -95.012591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922057942, states[0] = 8.706376, states[40]= 0.004839
Saving checkpoint... 
Iteration: 933727576, states[0] = -94.859689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945563541, states[0] = 6.336177, states[40]= 0.004756
Saving checkpoint... 
Iteration: 957858867, states[0] = -94.981754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970022092, states[0] = 20.778711, states[40]= 0.008013
Saving checkpoint... 
Iteration: 982335257, states[0] = -94.969754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994742072, states[0] = -94.882283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007442466, states[0] = -95.007858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019456957, states[0] = -95.010644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031605970, states[0] = -24.194299, states[40]= 0.000752
Saving checkpoint... 
Iteration: 1043398204, states[0] = -94.996537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055810705, states[0] = -94.953940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067669160, states[0] = -94.002645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080198125, states[0] = -94.803533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092030589, states[0] = 18.598356, states[40]= 0.005851
Saving checkpoint... 
Iteration: 1104271093, states[0] = -94.918703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116084130, states[0] = -4.923428, states[40]= 0.003395
Saving checkpoint... 
Iteration: 1128741040, states[0] = -94.880685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140326274, states[0] = -94.964316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152331710, states[0] = -94.967589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164088177, states[0] = -8.014322, states[40]= 0.002742
Saving checkpoint... 
Iteration: 1175655219, states[0] = -78.893236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187703669, states[0] = -94.815019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200219249, states[0] = -94.845020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212056689, states[0] = 9.216362, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1224419547, states[0] = -95.002444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236208794, states[0] = -94.825261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248319601, states[0] = -94.959967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260519985, states[0] = 21.200059, states[40]= 0.009408
Saving checkpoint... 
Iteration: 1272904938, states[0] = -94.998415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284824616, states[0] = -94.963181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297035377, states[0] = 17.098893, states[40]= 0.005407
Saving checkpoint... 
Iteration: 1309049969, states[0] = 11.853705, states[40]= 0.004922
Saving checkpoint... 
Iteration: 1321738895, states[0] = -94.877372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333695463, states[0] = -94.797603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344508293, states[0] = 23.610083, states[40]= 0.078745
Saving checkpoint... 
Iteration: 1354974879, states[0] = -95.013386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366650207, states[0] = -71.111868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378055475, states[0] = 9.704415, states[40]= 0.004865
Saving checkpoint... 
Iteration: 1389996453, states[0] = -95.016328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401810136, states[0] = -94.953293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413670120, states[0] = -94.188723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425310416, states[0] = -94.953480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437216085, states[0] = -94.839066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448918386, states[0] = -95.001994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460653921, states[0] = -76.751149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472336822, states[0] = -94.970303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484099177, states[0] = -17.836024, states[40]= 0.001140
Saving checkpoint... 
Iteration: 1495633921, states[0] = -51.775594, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1507843357, states[0] = 11.930015, states[40]= 0.005792
Saving checkpoint... 
Iteration: 1519658632, states[0] = -95.023990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532137579, states[0] = 14.233787, states[40]= 0.006160
Saving checkpoint... 
Iteration: 1544196516, states[0] = -32.445370, states[40]= 0.000358
Saving checkpoint... 
Iteration: 1556615916, states[0] = -95.201285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568562648, states[0] = -95.084942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581019829, states[0] = 20.877852, states[40]= 0.010904
Saving checkpoint... 
Iteration: 1592776878, states[0] = -12.053825, states[40]= 0.002190
Saving checkpoint... 
Iteration: 1604985612, states[0] = -95.291155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616486858, states[0] = -22.902323, states[40]= 0.000838
Saving checkpoint... 
Iteration: 1628864038, states[0] = -95.097918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640073371, states[0] = -95.283019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652444712, states[0] = 10.403352, states[40]= 0.005765
Saving checkpoint... 
Iteration: 1664013239, states[0] = -95.209492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676481358, states[0] = -17.007123, states[40]= 0.001366
Saving checkpoint... 
Iteration: 1688350150, states[0] = -95.260740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700739463, states[0] = 12.968696, states[40]= 0.006033
Saving checkpoint... 
Iteration: 1712675146, states[0] = -95.285269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725025594, states[0] = 18.899989, states[40]= 0.007842
Saving checkpoint... 
Iteration: 1736313306, states[0] = -95.209907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747793047, states[0] = -95.299163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759493531, states[0] = -95.299501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771600730, states[0] = -38.070482, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1783369223, states[0] = -95.114620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795492125, states[0] = -95.298490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807033156, states[0] = 17.137737, states[40]= 0.005459
Saving checkpoint... 
Iteration: 1819628436, states[0] = -48.775552, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1831788341, states[0] = -94.964357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844244575, states[0] = -94.905738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855801584, states[0] = -94.960886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868340911, states[0] = -94.982159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880396902, states[0] = -95.002451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892936650, states[0] = -95.010770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904707191, states[0] = -94.825048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917245624, states[0] = -94.889064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929168347, states[0] = -93.833582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941470732, states[0] = -95.013444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953665015, states[0] = -92.345461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966157973, states[0] = -83.636569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978336414, states[0] = -94.970067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990811148, states[0] = -94.953840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002468459, states[0] = -95.012075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015040421, states[0] = 15.373058, states[40]= 0.005141
Saving checkpoint... 
Iteration: 2027282861, states[0] = -94.930082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039364943, states[0] = -94.983695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050995184, states[0] = -95.015708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062421248, states[0] = -95.002279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073927496, states[0] = -95.003787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084897700, states[0] = -94.995630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096371715, states[0] = -94.986400, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892105
 - CaMKt in component CaMK (millimolar): 0.007103
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.609657
 - nass in component intracellular_ions (millimolar): 6.609717
 - ki in component intracellular_ions (millimolar): 145.366037
 - kss in component intracellular_ions (millimolar): 145.366017
 - cansr in component intracellular_ions (millimolar): 1.318793
 - cajsr in component intracellular_ions (millimolar): 1.280570
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879832
 - hs in component INa (dimensionless): 0.879827
 - j in component INa (dimensionless): 0.879797
 - hsp in component INa (dimensionless): 0.725511
 - jp in component INa (dimensionless): 0.879777
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709290
 - hLp in component INaL (dimensionless): 0.450601
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619819
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694431
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934659
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330069
 - xs1 in component IKs (dimensionless): 0.243384
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:56:23 (23356): called boinc_finish(0)

</stderr_txt>
]]>


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