𝕏

Task 55983043

Name HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_323_0
Workunit 26586275
Created 3 Jul 2024, 20:40:50 UTC
Sent 3 Jul 2024, 22:19:55 UTC
Report deadline 7 Jul 2024, 7:55:55 UTC
Received 5 Jul 2024, 23:56:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217971
Run time 1 hours 18 min 20 sec
CPU time 52 min 1 sec
Validate state Valid
Credit 60.16
Device peak FLOPS 5.38 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.19 MB
Peak swap size 5.26 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_323.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_323_0_r173811314_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_323_0_r173811314_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.604088
     * GNaL_b in INaL: 0.005673
     * Gto_b in Ito: 0.086584
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032056
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.160717
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.174157
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032579
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11924653, states[0] = -95.074275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24372729, states[0] = -95.023753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36530262, states[0] = 18.018580, states[40]= 0.005907
Saving checkpoint... 
Iteration: 48844451, states[0] = -94.978641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61332927, states[0] = -94.963913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73755259, states[0] = -94.891065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85924180, states[0] = -94.989264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98118064, states[0] = -37.213164, states[40]= 0.000192
Saving checkpoint... 
Iteration: 110142115, states[0] = -62.702170, states[40]= 0.000003
Saving checkpoint... 
Iteration: 122416021, states[0] = -94.981497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134262602, states[0] = -94.889348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146398930, states[0] = -94.975179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158491473, states[0] = -94.993659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170810171, states[0] = -94.931779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182722598, states[0] = -94.830377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194910311, states[0] = -94.977360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207082459, states[0] = -4.439929, states[40]= 0.003492
Saving checkpoint... 
Iteration: 219579152, states[0] = -2.226348, states[40]= 0.003897
Saving checkpoint... 
Iteration: 231847262, states[0] = -94.953456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244136475, states[0] = -55.986635, states[40]= 0.000010
Saving checkpoint... 
Iteration: 256034920, states[0] = 16.987248, states[40]= 0.005470
Saving checkpoint... 
Iteration: 268390110, states[0] = -94.970902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280473345, states[0] = -94.990076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292201633, states[0] = -94.790094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304128750, states[0] = -47.662912, states[40]= 0.000040
Saving checkpoint... 
Iteration: 316404073, states[0] = -94.975185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328627658, states[0] = -46.516125, states[40]= 0.000048
Saving checkpoint... 
Iteration: 338754907, states[0] = -94.877828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349409846, states[0] = -94.976794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360458240, states[0] = -94.987528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371431655, states[0] = -94.982222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382602013, states[0] = -21.570600, states[40]= 0.000869
Saving checkpoint... 
Iteration: 393431486, states[0] = -94.982168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404351541, states[0] = -94.955320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415253200, states[0] = -94.875605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426558875, states[0] = 7.943402, states[40]= 0.004819
Saving checkpoint... 
Iteration: 437609673, states[0] = -28.818158, states[40]= 0.000521
Saving checkpoint... 
Iteration: 448477509, states[0] = -94.990559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459147819, states[0] = -69.534660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470573708, states[0] = 0.964707, states[40]= 0.004347
Saving checkpoint... 
Iteration: 481704010, states[0] = -94.794783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492960769, states[0] = -94.987876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503904553, states[0] = -94.975191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514984046, states[0] = -94.991442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525808097, states[0] = -94.929343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536937932, states[0] = -94.983483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547814842, states[0] = -94.934109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559062506, states[0] = 6.386247, states[40]= 0.004759
Saving checkpoint... 
Iteration: 569397246, states[0] = -94.972956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580358218, states[0] = -94.958300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591248122, states[0] = -94.868811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602049420, states[0] = 11.732192, states[40]= 0.004934
Saving checkpoint... 
Iteration: 612789444, states[0] = -94.914253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623875201, states[0] = -94.965314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634983871, states[0] = -94.991339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646256672, states[0] = -94.879821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656951552, states[0] = -94.986118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668232332, states[0] = -94.845672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679284928, states[0] = -94.910124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690552189, states[0] = 10.654712, states[40]= 0.004899
Saving checkpoint... 
Iteration: 701633571, states[0] = -52.812520, states[40]= 0.000017
Saving checkpoint... 
Iteration: 712887179, states[0] = -94.969583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723886923, states[0] = -94.969488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735160328, states[0] = -89.027257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746256474, states[0] = -94.879509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757702578, states[0] = -94.791696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768447913, states[0] = -94.985353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779733530, states[0] = -94.847479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790586774, states[0] = -7.693555, states[40]= 0.002811
Saving checkpoint... 
Iteration: 801588889, states[0] = -9.449428, states[40]= 0.002439
Saving checkpoint... 
Iteration: 812449674, states[0] = -94.985661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823880528, states[0] = -94.967167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834536165, states[0] = 16.571229, states[40]= 0.005382
Saving checkpoint... 
Iteration: 845744133, states[0] = -94.863150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856943431, states[0] = -94.984409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868412515, states[0] = -94.977175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879324624, states[0] = -94.940278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890684884, states[0] = -94.750218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901358600, states[0] = -94.958259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912542558, states[0] = 14.311489, states[40]= 0.005083
Saving checkpoint... 
Iteration: 923391760, states[0] = -94.970974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935899022, states[0] = -94.973260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947353521, states[0] = -94.955900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959969794, states[0] = -94.989051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971818965, states[0] = -94.936596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984590913, states[0] = -11.212681, states[40]= 0.002086
Saving checkpoint... 
Iteration: 996521678, states[0] = 20.676152, states[40]= 0.008319
Saving checkpoint... 
Iteration: 1008946476, states[0] = -94.984914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020853598, states[0] = -94.955887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033289508, states[0] = -94.914031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045108271, states[0] = -27.488655, states[40]= 0.000585
Saving checkpoint... 
Iteration: 1057475277, states[0] = -94.989827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069478795, states[0] = -94.990336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081785070, states[0] = -94.909988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093612554, states[0] = -31.557372, states[40]= 0.000394
Saving checkpoint... 
Iteration: 1106228008, states[0] = -94.838405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118068237, states[0] = 3.755956, states[40]= 0.004606
Saving checkpoint... 
Iteration: 1130354680, states[0] = -94.956320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141867308, states[0] = -94.961840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154085951, states[0] = -7.037081, states[40]= 0.002952
Saving checkpoint... 
Iteration: 1165611375, states[0] = -30.434603, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1177456037, states[0] = -94.986595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189905651, states[0] = -94.975055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202082109, states[0] = -4.185399, states[40]= 0.003542
Saving checkpoint... 
Iteration: 1213972235, states[0] = -94.989263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226357744, states[0] = -94.957660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238193387, states[0] = -94.771953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250718176, states[0] = -94.821351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262855588, states[0] = -94.956653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275066932, states[0] = 4.377189, states[40]= 0.004649
Saving checkpoint... 
Iteration: 1287105135, states[0] = -24.521647, states[40]= 0.000724
Saving checkpoint... 
Iteration: 1299500863, states[0] = 45.867193, states[40]= 0.018025
Saving checkpoint... 
Iteration: 1311855040, states[0] = -94.956367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324048445, states[0] = 12.106478, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1335944844, states[0] = -94.984376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345852388, states[0] = -94.955101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357472750, states[0] = -94.989247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368903069, states[0] = -94.974187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380437937, states[0] = -94.982927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392491286, states[0] = -94.991825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404260334, states[0] = -94.883761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415994916, states[0] = -94.992267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427654837, states[0] = -80.355883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439419157, states[0] = -94.978531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450953732, states[0] = -94.985997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462721806, states[0] = -94.827649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474206724, states[0] = -94.799542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486269300, states[0] = -94.893905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497771084, states[0] = -94.895817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510101740, states[0] = -95.116077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522053152, states[0] = -94.923672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534542621, states[0] = 11.555744, states[40]= 0.005858
Saving checkpoint... 
Iteration: 1546308036, states[0] = -46.545056, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1558915100, states[0] = -55.413660, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1570934299, states[0] = -84.408496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583477870, states[0] = -13.845467, states[40]= 0.001843
Saving checkpoint... 
Iteration: 1594780325, states[0] = -95.261096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607236620, states[0] = -88.676676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619073072, states[0] = -95.257056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631300691, states[0] = -95.162342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642726709, states[0] = -95.205944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654919058, states[0] = -61.136231, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1666728722, states[0] = -95.209189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679070611, states[0] = -95.256260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690984307, states[0] = -95.128996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703304269, states[0] = -95.169995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715373751, states[0] = -95.259114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727202021, states[0] = -40.615473, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1738457349, states[0] = -95.243801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750093881, states[0] = -95.149806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761929743, states[0] = 17.096776, states[40]= 0.007009
Saving checkpoint... 
Iteration: 1774341128, states[0] = -93.147839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785828574, states[0] = -95.209215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798115169, states[0] = -95.188906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810151990, states[0] = -81.894276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822738266, states[0] = -94.890626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834494774, states[0] = -95.018129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846695862, states[0] = -94.795394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858746530, states[0] = -94.878729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871451912, states[0] = -94.994034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883225152, states[0] = -94.839350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895522158, states[0] = 20.532887, states[40]= 0.008047
Saving checkpoint... 
Iteration: 1907477254, states[0] = -94.992482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920145890, states[0] = -67.168088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1932038619, states[0] = 15.706202, states[40]= 0.005241
Saving checkpoint... 
Iteration: 1944215740, states[0] = -94.817423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956252012, states[0] = -94.873708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968878897, states[0] = -94.966240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980719720, states[0] = -94.823920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993109496, states[0] = -28.662697, states[40]= 0.000529
Saving checkpoint... 
Iteration: 2005046114, states[0] = 12.988170, states[40]= 0.004991
Saving checkpoint... 
Iteration: 2017727294, states[0] = -94.836676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029528466, states[0] = 18.980527, states[40]= 0.006197
Saving checkpoint... 
Iteration: 2041614558, states[0] = -33.475090, states[40]= 0.000314
Saving checkpoint... 
Iteration: 2053058726, states[0] = 8.005494, states[40]= 0.004821
Saving checkpoint... 
Iteration: 2064544478, states[0] = 13.602290, states[40]= 0.005029
Saving checkpoint... 
Iteration: 2074938756, states[0] = -94.982604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086860011, states[0] = -94.958059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098278169, states[0] = -94.902658, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.868257
 - CaMKt in component CaMK (millimolar): 0.007010
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.568580
 - nass in component intracellular_ions (millimolar): 6.568640
 - ki in component intracellular_ions (millimolar): 145.408476
 - kss in component intracellular_ions (millimolar): 145.408457
 - cansr in component intracellular_ions (millimolar): 1.313254
 - cajsr in component intracellular_ions (millimolar): 1.275230
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003631
 - hf in component INa (dimensionless): 0.879417
 - hs in component INa (dimensionless): 0.879412
 - j in component INa (dimensionless): 0.879382
 - hsp in component INa (dimensionless): 0.724730
 - jp in component INa (dimensionless): 0.879362
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708980
 - hLp in component INaL (dimensionless): 0.450841
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621070
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695940
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935899
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001604
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328412
 - xs1 in component IKs (dimensionless): 0.240821
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997346
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:56:37 (24684): called boinc_finish(0)

</stderr_txt>
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