𝕏

Task 55983009

Name HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114_0
Workunit 26586258
Created 3 Jul 2024, 20:40:49 UTC
Sent 3 Jul 2024, 21:46:02 UTC
Report deadline 7 Jul 2024, 7:22:02 UTC
Received 4 Jul 2024, 2:18:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237332
Run time 3 hours 27 min 42 sec
CPU time 3 hours 17 min 48 sec
Validate state Valid
Credit 61.40
Device peak FLOPS 4.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.04 MB
Peak swap size 32.63 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114_0_r2137179703_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114_0_r2137179703_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.187108
     * GNaL_b in INaL: 0.005631
     * Gto_b in Ito: 0.081299
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031710
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.167785
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.706006
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030134
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14510741, states[0] = 22.711854, states[40]= 0.043838
Saving checkpoint... 
Iteration: 29448659, states[0] = -95.081752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43782188, states[0] = -94.990844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58343299, states[0] = -95.021517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73404806, states[0] = -95.037812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88231746, states[0] = -94.909557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102957264, states[0] = -95.042490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117498750, states[0] = -95.046647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132989616, states[0] = -95.044382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148225061, states[0] = -94.892707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163301621, states[0] = -94.978401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177983880, states[0] = -95.042147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192941041, states[0] = -95.034951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207558501, states[0] = 8.090707, states[40]= 0.004893
Saving checkpoint... 
Iteration: 222370752, states[0] = -95.015092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237101678, states[0] = -21.488044, states[40]= 0.000880
Saving checkpoint... 
Iteration: 251853827, states[0] = -95.007992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266423293, states[0] = -95.030779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280983371, states[0] = -95.041507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295652620, states[0] = -78.186207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310772927, states[0] = -94.952706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325516744, states[0] = 22.051158, states[40]= 0.014056
Saving checkpoint... 
Iteration: 339909810, states[0] = -95.027344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354631182, states[0] = -50.618839, states[40]= 0.000025
Saving checkpoint... 
Iteration: 369042082, states[0] = 14.604151, states[40]= 0.005208
Saving checkpoint... 
Iteration: 384475966, states[0] = -95.040394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398747664, states[0] = -94.923937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412893992, states[0] = -95.022784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427689651, states[0] = -94.824609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442452937, states[0] = -95.036680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457076355, states[0] = -0.633674, states[40]= 0.004183
Saving checkpoint... 
Iteration: 471863278, states[0] = -95.011836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486686065, states[0] = -94.816206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501548007, states[0] = 12.343810, states[40]= 0.005050
Saving checkpoint... 
Iteration: 515919834, states[0] = -95.029760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530953330, states[0] = -95.036693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545492082, states[0] = -95.042428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560001272, states[0] = 48.440668, states[40]= 0.047420
Saving checkpoint... 
Iteration: 574149441, states[0] = -72.961528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588928900, states[0] = -95.031810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603451109, states[0] = -95.036250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618025568, states[0] = 20.060199, states[40]= 0.006991
Saving checkpoint... 
Iteration: 633124596, states[0] = -43.660365, states[40]= 0.000075
Saving checkpoint... 
Iteration: 647850775, states[0] = -95.006292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662815494, states[0] = -94.986908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677567163, states[0] = 4.210998, states[40]= 0.004693
Saving checkpoint... 
Iteration: 691950522, states[0] = -95.036087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707097086, states[0] = -17.131894, states[40]= 0.001215
Saving checkpoint... 
Iteration: 721688299, states[0] = -94.821384, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114_0_r2137179703_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703224041842062_ORdGradInc_k_26-Pueyo_APDR-conf_114_0_r2137179703_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.187108
     * GNaL_b in INaL: 0.005631
     * Gto_b in Ito: 0.081299
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031710
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.167785
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.706006
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030134
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 721688299
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.821384 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 735990353, states[0] = -95.042093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751018086, states[0] = 21.797455, states[40]= 0.011829
Saving checkpoint... 
Iteration: 765565718, states[0] = 4.893536, states[40]= 0.004738
Saving checkpoint... 
Iteration: 780209350, states[0] = -94.863765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795074105, states[0] = 0.651021, states[40]= 0.004354
Saving checkpoint... 
Iteration: 809954304, states[0] = -95.036686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824624465, states[0] = -43.525575, states[40]= 0.000077
Saving checkpoint... 
Iteration: 839011035, states[0] = 23.167267, states[40]= 0.041155
Saving checkpoint... 
Iteration: 853113202, states[0] = -32.427048, states[40]= 0.000359
Saving checkpoint... 
Iteration: 867521209, states[0] = 21.142249, states[40]= 0.008830
Saving checkpoint... 
Iteration: 882585101, states[0] = -6.545976, states[40]= 0.003083
Saving checkpoint... 
Iteration: 897529467, states[0] = 18.938849, states[40]= 0.006205
Saving checkpoint... 
Iteration: 912204098, states[0] = -94.853752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926685343, states[0] = -94.814072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941219941, states[0] = -94.882430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956146326, states[0] = -68.432448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971124762, states[0] = -43.830990, states[40]= 0.000073
Saving checkpoint... 
Iteration: 985689295, states[0] = -94.823461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000170840, states[0] = -94.609945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014348676, states[0] = -95.005081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029242997, states[0] = -94.917371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043775979, states[0] = -94.955217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058474976, states[0] = -95.039821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073143134, states[0] = -64.264547, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1087920671, states[0] = -95.029596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101864421, states[0] = -95.011899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116422993, states[0] = -95.030127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130630838, states[0] = -50.246333, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1144713758, states[0] = -94.871549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158936007, states[0] = -95.032971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173095672, states[0] = -15.798592, states[40]= 0.001368
Saving checkpoint... 
Iteration: 1187583405, states[0] = -5.266327, states[40]= 0.003354
Saving checkpoint... 
Iteration: 1202174557, states[0] = -94.740017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216935927, states[0] = -95.032917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231683403, states[0] = -94.808391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246375872, states[0] = -95.016199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261033520, states[0] = 17.645206, states[40]= 0.005725
Saving checkpoint... 
Iteration: 1275475218, states[0] = -95.039717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289787871, states[0] = -94.965871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303942742, states[0] = -95.034234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318729740, states[0] = -94.898025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333498242, states[0] = -95.042661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347969602, states[0] = -95.038840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362391033, states[0] = -95.021259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376932859, states[0] = -95.032169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391361905, states[0] = -95.010684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405961968, states[0] = -95.037602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420509051, states[0] = 23.865355, states[40]= 0.065255
Saving checkpoint... 
Iteration: 1435501198, states[0] = 48.421573, states[40]= 0.042308
Saving checkpoint... 
Iteration: 1449765338, states[0] = -94.944109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463969560, states[0] = -95.038760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478476620, states[0] = -95.039789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492737200, states[0] = -94.909005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507489832, states[0] = -95.257037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522086777, states[0] = -95.141287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536456836, states[0] = -95.067471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550566012, states[0] = -95.111660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564654279, states[0] = -95.063513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579140400, states[0] = -95.255323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593461945, states[0] = -95.110597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608334123, states[0] = 15.422617, states[40]= 0.006594
Saving checkpoint... 
Iteration: 1622133389, states[0] = 15.744505, states[40]= 0.006673
Saving checkpoint... 
Iteration: 1636218072, states[0] = 21.600005, states[40]= 0.013314
Saving checkpoint... 
Iteration: 1649624203, states[0] = -95.239501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663862297, states[0] = -0.046995, states[40]= 0.004807
Saving checkpoint... 
Iteration: 1678575372, states[0] = -11.375021, states[40]= 0.002345
Saving checkpoint... 
Iteration: 1692735683, states[0] = -88.522506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707240948, states[0] = -95.261403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721599314, states[0] = -95.199664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735860870, states[0] = 0.917097, states[40]= 0.004948
Saving checkpoint... 
Iteration: 1750153493, states[0] = -95.275100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764297202, states[0] = -95.310504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777705692, states[0] = -95.211068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791423963, states[0] = -68.151675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1805644541, states[0] = -71.797758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1819365155, states[0] = -95.048194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832474417, states[0] = -95.064544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846612647, states[0] = -32.963563, states[40]= 0.000336
Saving checkpoint... 
Iteration: 1860891236, states[0] = -95.031919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875265239, states[0] = -94.950946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889651224, states[0] = -76.419611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904011585, states[0] = 23.008259, states[40]= 0.036356
Saving checkpoint... 
Iteration: 1918388771, states[0] = -95.022136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932434212, states[0] = -95.033373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946395858, states[0] = -95.023198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960191774, states[0] = -94.828761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973993879, states[0] = -95.042072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988398813, states[0] = -95.023425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002435128, states[0] = -95.032364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016412467, states[0] = -95.027021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030376469, states[0] = -95.015934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044454552, states[0] = -95.035936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058711533, states[0] = -94.866928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073390897, states[0] = -95.020727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087705927, states[0] = -94.856456, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.918204
 - CaMKt in component CaMK (millimolar): 0.006972
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.567955
 - nass in component intracellular_ions (millimolar): 6.568015
 - ki in component intracellular_ions (millimolar): 145.409366
 - kss in component intracellular_ions (millimolar): 145.409347
 - cansr in component intracellular_ions (millimolar): 1.313100
 - cajsr in component intracellular_ions (millimolar): 1.275193
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880284
 - hs in component INa (dimensionless): 0.880280
 - j in component INa (dimensionless): 0.880251
 - hsp in component INa (dimensionless): 0.726365
 - jp in component INa (dimensionless): 0.880232
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710541
 - hLp in component INaL (dimensionless): 0.453080
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621980
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696993
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935358
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001609
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330169
 - xs1 in component IKs (dimensionless): 0.240641
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:17:42 (69800): called boinc_finish(0)

</stderr_txt>
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