𝕏

Task 55980660

Name HuVeMOp_20240703223042594746_ORdGradInc_k_26-Pueyo_APDR-conf_359_0
Workunit 26585108
Created 3 Jul 2024, 20:31:02 UTC
Sent 3 Jul 2024, 21:29:08 UTC
Report deadline 7 Jul 2024, 7:05:08 UTC
Received 5 Jul 2024, 15:16:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232933
Run time 2 hours 2 min 56 sec
CPU time 1 hours 49 min 13 sec
Validate state Valid
Credit 63.08
Device peak FLOPS 3.46 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.28 MB
Peak swap size 5.16 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703223042594746_ORdGradInc_k_26-Pueyo_APDR-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703223042594746_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r1147711630_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703223042594746_ORdGradInc_k_26-Pueyo_APDR-conf_359_0_r1147711630_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.732678
     * GNaL_b in INaL: 0.005925
     * Gto_b in Ito: 0.085549
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031515
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.160626
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.336158
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9895701, states[0] = -95.079309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22575758, states[0] = -1.275141, states[40]= 0.004077
Saving checkpoint... 
Iteration: 35397218, states[0] = -95.025180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48603055, states[0] = -22.868531, states[40]= 0.000812
Saving checkpoint... 
Iteration: 61460858, states[0] = -95.020004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70598182, states[0] = -17.685573, states[40]= 0.001157
Saving checkpoint... 
Iteration: 83372905, states[0] = -94.988825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96279637, states[0] = -94.926874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109428560, states[0] = -95.001204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122005281, states[0] = 27.502632, states[40]= 0.144729
Saving checkpoint... 
Iteration: 134848389, states[0] = -94.971399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147668866, states[0] = -93.923386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160780789, states[0] = -94.922983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173475920, states[0] = -95.006721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186571085, states[0] = 2.690053, states[40]= 0.004532
Saving checkpoint... 
Iteration: 199456744, states[0] = -95.003254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212163268, states[0] = -90.763318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225155429, states[0] = -78.957124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237773205, states[0] = -94.914527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250504391, states[0] = 30.063578, states[40]= 0.156580
Saving checkpoint... 
Iteration: 263548963, states[0] = 12.139992, states[40]= 0.004968
Saving checkpoint... 
Iteration: 276191260, states[0] = -94.783395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288963444, states[0] = -95.004092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301994282, states[0] = -95.008559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314558533, states[0] = 8.355012, states[40]= 0.004850
Saving checkpoint... 
Iteration: 327638409, states[0] = -56.545512, states[40]= 0.000009
Saving checkpoint... 
Iteration: 340448127, states[0] = -95.001283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353108021, states[0] = -26.184590, states[40]= 0.000660
Saving checkpoint... 
Iteration: 366029723, states[0] = 18.806758, states[40]= 0.006054
Saving checkpoint... 
Iteration: 378626279, states[0] = -43.683569, states[40]= 0.000076
Saving checkpoint... 
Iteration: 391333685, states[0] = -94.961557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403983633, states[0] = -95.007077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416888356, states[0] = -94.985758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429567262, states[0] = 4.542557, states[40]= 0.004673
Saving checkpoint... 
Iteration: 441718442, states[0] = -94.837972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454076710, states[0] = -0.300445, states[40]= 0.004196
Saving checkpoint... 
Iteration: 465542467, states[0] = 14.560301, states[40]= 0.005117
Saving checkpoint... 
Iteration: 476436639, states[0] = -94.998845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487771910, states[0] = -94.912909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497756954, states[0] = -94.895812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510360777, states[0] = -94.975052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522960924, states[0] = -95.003491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534727057, states[0] = -94.852787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548147348, states[0] = -67.016339, states[40]= 0.000002
Saving checkpoint... 
Iteration: 561105151, states[0] = -23.512258, states[40]= 0.000783
Saving checkpoint... 
Iteration: 573986265, states[0] = -95.007325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586920344, states[0] = -94.994985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599547694, states[0] = 12.621908, states[40]= 0.004989
Saving checkpoint... 
Iteration: 612565599, states[0] = 5.305976, states[40]= 0.004719
Saving checkpoint... 
Iteration: 623521238, states[0] = 20.953357, states[40]= 0.008663
Saving checkpoint... 
Iteration: 636548259, states[0] = 12.408210, states[40]= 0.004980
Saving checkpoint... 
Iteration: 649214730, states[0] = -94.831068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661866484, states[0] = -94.977390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674493205, states[0] = -95.008165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687041657, states[0] = 14.853627, states[40]= 0.005145
Saving checkpoint... 
Iteration: 699878819, states[0] = -94.982201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712268473, states[0] = -94.909062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725062603, states[0] = 6.633450, states[40]= 0.004785
Saving checkpoint... 
Iteration: 737834874, states[0] = -94.962002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750427049, states[0] = -94.996507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763294418, states[0] = -94.933993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775907834, states[0] = -94.991537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788534850, states[0] = 17.208658, states[40]= 0.005514
Saving checkpoint... 
Iteration: 801622507, states[0] = -39.918295, states[40]= 0.000133
Saving checkpoint... 
Iteration: 814177388, states[0] = -94.692143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827164912, states[0] = -92.131685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839460525, states[0] = -95.003216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852382877, states[0] = -94.983573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865103944, states[0] = -22.388535, states[40]= 0.000837
Saving checkpoint... 
Iteration: 878116928, states[0] = -34.542231, states[40]= 0.000280
Saving checkpoint... 
Iteration: 891092898, states[0] = -12.180049, states[40]= 0.001908
Saving checkpoint... 
Iteration: 903885255, states[0] = -94.984375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916838000, states[0] = -94.963618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929651610, states[0] = -72.878733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941891967, states[0] = -94.986613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954517601, states[0] = 21.640400, states[40]= 0.012401
Saving checkpoint... 
Iteration: 967434558, states[0] = -94.998071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980183495, states[0] = -94.757757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992900257, states[0] = -94.989185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005017425, states[0] = 21.670209, states[40]= 0.012685
Saving checkpoint... 
Iteration: 1017796335, states[0] = -94.935423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030352067, states[0] = -94.970727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039200091, states[0] = -94.802124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049027026, states[0] = 19.565349, states[40]= 0.006518
Saving checkpoint... 
Iteration: 1066030392, states[0] = 18.609255, states[40]= 0.005964
Saving checkpoint... 
Iteration: 1083414661, states[0] = -94.993198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100784012, states[0] = -94.924543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117834494, states[0] = -94.961538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135120078, states[0] = -37.554527, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1152135442, states[0] = -53.308900, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1169369772, states[0] = -94.978402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186756005, states[0] = -94.894184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204160144, states[0] = -86.790475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222075038, states[0] = 0.635217, states[40]= 0.004317
Saving checkpoint... 
Iteration: 1239370875, states[0] = -94.978798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255743596, states[0] = -94.877677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273231058, states[0] = -94.858815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290645952, states[0] = -65.258362, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1308242447, states[0] = -94.876011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325800400, states[0] = -94.938506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342414769, states[0] = -94.993057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358935452, states[0] = -94.998011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376019840, states[0] = 21.234448, states[40]= 0.009720
Saving checkpoint... 
Iteration: 1392780676, states[0] = -94.921180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410068122, states[0] = 4.139657, states[40]= 0.004646
Saving checkpoint... 
Iteration: 1427084348, states[0] = -5.208429, states[40]= 0.003340
Saving checkpoint... 
Iteration: 1444085339, states[0] = -5.936274, states[40]= 0.003189
Saving checkpoint... 
Iteration: 1461898278, states[0] = -94.988274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478528784, states[0] = 19.078252, states[40]= 0.006196
Saving checkpoint... 
Iteration: 1495646952, states[0] = -66.509991, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1513366999, states[0] = -95.055160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530658132, states[0] = 3.572703, states[40]= 0.005202
Saving checkpoint... 
Iteration: 1548408028, states[0] = -45.282885, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1565808153, states[0] = -45.856605, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1579217821, states[0] = 21.498935, states[40]= 0.013568
Saving checkpoint... 
Iteration: 1597822209, states[0] = 20.121306, states[40]= 0.009351
Saving checkpoint... 
Iteration: 1615932761, states[0] = -80.132037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634219017, states[0] = -59.562536, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1651948721, states[0] = -94.790786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670509781, states[0] = -48.329256, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1689512406, states[0] = -95.199052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707573463, states[0] = -95.273631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726176680, states[0] = -95.276367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743498040, states[0] = -95.172986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756166104, states[0] = -95.267105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760957298, states[0] = -95.258531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781166059, states[0] = -2.433590, states[40]= 0.004368
Saving checkpoint... 
Iteration: 1801060900, states[0] = 5.774451, states[40]= 0.004899
Saving checkpoint... 
Iteration: 1814717999, states[0] = -94.879884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827637052, states[0] = -57.482338, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1843540465, states[0] = 14.996962, states[40]= 0.005191
Saving checkpoint... 
Iteration: 1860631541, states[0] = -49.998241, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1879225751, states[0] = -94.856885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894747662, states[0] = -94.887378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911461052, states[0] = -95.005280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930368305, states[0] = -94.978825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942893631, states[0] = -94.987529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956928939, states[0] = -94.996822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977283942, states[0] = -94.924246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995568216, states[0] = 4.089938, states[40]= 0.004643
Saving checkpoint... 
Iteration: 2012633623, states[0] = -51.362932, states[40]= 0.000023
Saving checkpoint... 
Iteration: 2031235379, states[0] = -94.865102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047713289, states[0] = -94.827454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064807544, states[0] = -94.943452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083684202, states[0] = -94.760344, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883892
 - CaMKt in component CaMK (millimolar): 0.007046
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.608272
 - nass in component intracellular_ions (millimolar): 6.608332
 - ki in component intracellular_ions (millimolar): 145.368386
 - kss in component intracellular_ions (millimolar): 145.368367
 - cansr in component intracellular_ions (millimolar): 1.315440
 - cajsr in component intracellular_ions (millimolar): 1.277302
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879689
 - hs in component INa (dimensionless): 0.879684
 - j in component INa (dimensionless): 0.879654
 - hsp in component INa (dimensionless): 0.725242
 - jp in component INa (dimensionless): 0.879635
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709047
 - hLp in component INaL (dimensionless): 0.450279
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619694
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694279
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934791
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332053
 - xs1 in component IKs (dimensionless): 0.242998
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:16:18 (5676): called boinc_finish(0)

</stderr_txt>
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