𝕏

Task 55979633

Name HuVeMOp_20240703220139192716_ORdGradInc_k_26-Pueyo_APDR-conf_880_1
Workunit 26584705
Created 3 Jul 2024, 20:02:26 UTC
Sent 3 Jul 2024, 21:23:27 UTC
Report deadline 7 Jul 2024, 6:59:27 UTC
Received 4 Jul 2024, 3:27:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233905
Run time 3 hours 11 min 16 sec
CPU time 3 hours 3 min 50 sec
Validate state Valid
Credit 65.01
Device peak FLOPS 2.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.03 MB
Peak swap size 6.21 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703220139192716_ORdGradInc_k_26-Pueyo_APDR-conf_880.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703220139192716_ORdGradInc_k_26-Pueyo_APDR-conf_880_1_r1765797299_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703220139192716_ORdGradInc_k_26-Pueyo_APDR-conf_880_1_r1765797299_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.099697
     * GNaL_b in INaL: 0.005993
     * Gto_b in Ito: 0.082389
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031490
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.161873
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.335801
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13105579, states[0] = -28.316758, states[40]= 0.000520
Saving checkpoint... 
Iteration: 26354109, states[0] = -95.015502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39697447, states[0] = -94.830237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52769176, states[0] = -94.928304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65891404, states[0] = -94.995252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78997565, states[0] = -95.012000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92164252, states[0] = -92.659579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105497134, states[0] = -95.006783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118701297, states[0] = -94.808619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131894761, states[0] = -94.984219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145026406, states[0] = 19.829632, states[40]= 0.006888
Saving checkpoint... 
Iteration: 158278643, states[0] = -94.917457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170421625, states[0] = -94.990128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183017589, states[0] = 21.880022, states[40]= 0.012876
Saving checkpoint... 
Iteration: 195167257, states[0] = -93.740480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207665367, states[0] = -92.999305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219302665, states[0] = -94.936959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230958348, states[0] = -94.996973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242468322, states[0] = -94.998546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254291921, states[0] = -94.928356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266974984, states[0] = -94.999485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279354503, states[0] = -94.967113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290750799, states[0] = -94.885739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303179394, states[0] = -94.737013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315254572, states[0] = -94.890406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327632669, states[0] = -51.089939, states[40]= 0.000023
Saving checkpoint... 
Iteration: 339338598, states[0] = -94.959326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350759292, states[0] = -94.896000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362205115, states[0] = -94.812907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374975993, states[0] = -94.999528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386918256, states[0] = -94.988531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398981335, states[0] = -95.000259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410894203, states[0] = -94.981871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423126156, states[0] = -44.229250, states[40]= 0.000069
Saving checkpoint... 
Iteration: 435802598, states[0] = -94.936620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448310914, states[0] = -94.942581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459860999, states[0] = -94.969808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472132387, states[0] = -50.786037, states[40]= 0.000024
Saving checkpoint... 
Iteration: 484805559, states[0] = -94.938772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497323272, states[0] = -94.950557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509479124, states[0] = -94.999887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521082627, states[0] = -4.282383, states[40]= 0.003539
Saving checkpoint... 
Iteration: 533079024, states[0] = -1.915623, states[40]= 0.003970
Saving checkpoint... 
Iteration: 545412184, states[0] = -94.986894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558160908, states[0] = -89.172406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569423913, states[0] = -94.989776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580791300, states[0] = -94.927581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593200183, states[0] = -94.803100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604811905, states[0] = -94.943164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616537728, states[0] = 16.249861, states[40]= 0.005449
Saving checkpoint... 
Iteration: 628565832, states[0] = 5.039852, states[40]= 0.004737
Saving checkpoint... 
Iteration: 640079225, states[0] = -2.040683, states[40]= 0.003949
Saving checkpoint... 
Iteration: 651435105, states[0] = -94.992209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663774206, states[0] = -94.911881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675999315, states[0] = -95.002340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688077358, states[0] = -0.907134, states[40]= 0.004128
Saving checkpoint... 
Iteration: 699984308, states[0] = -95.000475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711431183, states[0] = -94.991332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723238707, states[0] = -94.869146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735066840, states[0] = 4.572660, states[40]= 0.004706
Saving checkpoint... 
Iteration: 746765108, states[0] = -94.902317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759506876, states[0] = 25.554503, states[40]= 0.107025
Saving checkpoint... 
Iteration: 771500261, states[0] = -62.892062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782409493, states[0] = -94.986039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794370950, states[0] = -94.973615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805716988, states[0] = -94.834507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817257079, states[0] = -94.893109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828261646, states[0] = -94.898408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838700319, states[0] = -94.803220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849607776, states[0] = -26.460508, states[40]= 0.000640
Saving checkpoint... 
Iteration: 859928267, states[0] = -94.990596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871383188, states[0] = -94.978009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883007931, states[0] = 24.569489, states[40]= 0.085384
Saving checkpoint... 
Iteration: 893473143, states[0] = -94.998797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905188658, states[0] = -94.778214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915324959, states[0] = -94.951321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925267340, states[0] = -94.904625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936562672, states[0] = 6.459391, states[40]= 0.004816
Saving checkpoint... 
Iteration: 948358578, states[0] = -94.968476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958683096, states[0] = -94.760500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970443432, states[0] = -94.993701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980620111, states[0] = -38.186227, states[40]= 0.000168
Saving checkpoint... 
Iteration: 991111891, states[0] = -30.330370, states[40]= 0.000453
Saving checkpoint... 
Iteration: 1002976751, states[0] = -94.999253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012911475, states[0] = -94.986424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024017739, states[0] = 21.855548, states[40]= 0.012640
Saving checkpoint... 
Iteration: 1034444650, states[0] = -94.993898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045751187, states[0] = -94.885748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056402336, states[0] = -94.983893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067549295, states[0] = 11.944745, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1079031238, states[0] = 18.419435, states[40]= 0.006036
Saving checkpoint... 
Iteration: 1090121158, states[0] = -39.211005, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1101599436, states[0] = -18.642233, states[40]= 0.001071
Saving checkpoint... 
Iteration: 1113012422, states[0] = 22.841356, states[40]= 0.031010
Saving checkpoint... 
Iteration: 1124660340, states[0] = -88.428452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134783586, states[0] = -94.920517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145556854, states[0] = 8.929508, states[40]= 0.004918
Saving checkpoint... 
Iteration: 1156854678, states[0] = -94.966630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167368065, states[0] = -94.972264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177667651, states[0] = -93.843949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188977608, states[0] = -94.999261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199653491, states[0] = -77.195759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209824479, states[0] = -94.950854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220798112, states[0] = -94.932708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231892324, states[0] = -94.980786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243016238, states[0] = 22.133475, states[40]= 0.015508
Saving checkpoint... 
Iteration: 1254463106, states[0] = -94.997027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264725087, states[0] = -94.847951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275989026, states[0] = -95.000735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286925503, states[0] = -94.989708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297604832, states[0] = -23.701205, states[40]= 0.000769
Saving checkpoint... 
Iteration: 1308406320, states[0] = -94.984858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319932369, states[0] = -94.991219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331365692, states[0] = -94.971216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342070146, states[0] = 2.981963, states[40]= 0.004583
Saving checkpoint... 
Iteration: 1352722808, states[0] = -94.844135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362911674, states[0] = -94.986263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373880991, states[0] = -94.976943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383844407, states[0] = -94.961646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393763351, states[0] = -94.899980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403768004, states[0] = -94.905041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413931573, states[0] = -94.990989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424155614, states[0] = -80.789508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434236026, states[0] = -94.864819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445891689, states[0] = -94.980455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458483998, states[0] = -94.999972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471649801, states[0] = -71.488316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484888073, states[0] = -94.979269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498033544, states[0] = 17.677432, states[40]= 0.005779
Saving checkpoint... 
Iteration: 1511411578, states[0] = 23.932766, states[40]= 0.038626
Saving checkpoint... 
Iteration: 1524550826, states[0] = -95.210797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537517009, states[0] = 22.120103, states[40]= 0.015569
Saving checkpoint... 
Iteration: 1550646402, states[0] = -95.224533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563684635, states[0] = -20.356652, states[40]= 0.001017
Saving checkpoint... 
Iteration: 1576869928, states[0] = -5.517183, states[40]= 0.003705
Saving checkpoint... 
Iteration: 1589996533, states[0] = -95.278406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602311932, states[0] = 23.485426, states[40]= 0.035764
Saving checkpoint... 
Iteration: 1615378230, states[0] = -95.124526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628644427, states[0] = -95.236112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641749666, states[0] = -94.894539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655063741, states[0] = -95.256604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668031592, states[0] = 16.560141, states[40]= 0.006960
Saving checkpoint... 
Iteration: 1681118716, states[0] = -95.203181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694128769, states[0] = 17.752630, states[40]= 0.007430
Saving checkpoint... 
Iteration: 1707404676, states[0] = -42.774545, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1720457253, states[0] = -95.250811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733643648, states[0] = -95.236314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746912795, states[0] = 23.180237, states[40]= 0.030217
Saving checkpoint... 
Iteration: 1760112839, states[0] = 23.166225, states[40]= 0.029966
Saving checkpoint... 
Iteration: 1773498689, states[0] = -95.169349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786671743, states[0] = -95.110624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799570132, states[0] = -95.106533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812497389, states[0] = -95.048273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825799492, states[0] = -94.966232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839078643, states[0] = -2.431648, states[40]= 0.003906
Saving checkpoint... 
Iteration: 1852108876, states[0] = -28.391140, states[40]= 0.000546
Saving checkpoint... 
Iteration: 1865358564, states[0] = -94.978206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878388191, states[0] = -94.986053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891650205, states[0] = -72.597004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1904977122, states[0] = -95.001921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917973878, states[0] = -95.000427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931286670, states[0] = -94.924236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944520938, states[0] = 21.191036, states[40]= 0.009208
Saving checkpoint... 
Iteration: 1957704738, states[0] = -94.811849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970736317, states[0] = -94.865346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983568870, states[0] = 3.599690, states[40]= 0.004635
Saving checkpoint... 
Iteration: 1995969641, states[0] = -94.997774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009380934, states[0] = -94.976636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022409871, states[0] = -94.985436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035750093, states[0] = -94.883771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049003424, states[0] = 35.155922, states[40]= 0.141472
Saving checkpoint... 
Iteration: 2062348595, states[0] = -94.963246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075617171, states[0] = -35.346042, states[40]= 0.000248
Saving checkpoint... 
Iteration: 2088636783, states[0] = -55.571015, states[40]= 0.000011
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.877386
 - CaMKt in component CaMK (millimolar): 0.006907
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.612946
 - nass in component intracellular_ions (millimolar): 6.613005
 - ki in component intracellular_ions (millimolar): 145.365935
 - kss in component intracellular_ions (millimolar): 145.365916
 - cansr in component intracellular_ions (millimolar): 1.307390
 - cajsr in component intracellular_ions (millimolar): 1.269472
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003627
 - hf in component INa (dimensionless): 0.879576
 - hs in component INa (dimensionless): 0.879571
 - j in component INa (dimensionless): 0.879543
 - hsp in component INa (dimensionless): 0.725030
 - jp in component INa (dimensionless): 0.879523
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709120
 - hLp in component INaL (dimensionless): 0.450803
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620467
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695094
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934814
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335116
 - xs1 in component IKs (dimensionless): 0.242152
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:57:01 (2540): called boinc_finish(0)

</stderr_txt>
]]>


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