𝕏

Task 55976204

Name HuVeMOp_20240703214139931978_ORdGradInc_k_26-Pueyo_APDR-conf_278_0
Workunit 26583028
Created 3 Jul 2024, 19:42:25 UTC
Sent 3 Jul 2024, 21:02:26 UTC
Report deadline 7 Jul 2024, 6:38:26 UTC
Received 6 Jul 2024, 1:58:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234951
Run time 2 hours 33 min 48 sec
CPU time 2 hours 33 min 26 sec
Validate state Valid
Credit 63.47
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214139931978_ORdGradInc_k_26-Pueyo_APDR-conf_278.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214139931978_ORdGradInc_k_26-Pueyo_APDR-conf_278_0_r1926750136_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214139931978_ORdGradInc_k_26-Pueyo_APDR-conf_278_0_r1926750136_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.508272
     * GNaL_b in INaL: 0.005958
     * Gto_b in Ito: 0.082935
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031441
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.165585
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.831545
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029267
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13643215, states[0] = -69.762640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28114718, states[0] = -35.485323, states[40]= 0.000243
Saving checkpoint... 
Iteration: 42957982, states[0] = -95.071710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57618868, states[0] = -37.732945, states[40]= 0.000181
Saving checkpoint... 
Iteration: 71737758, states[0] = -94.924611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85590606, states[0] = -10.597276, states[40]= 0.002219
Saving checkpoint... 
Iteration: 99649711, states[0] = -71.505406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113808645, states[0] = -94.988662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127756615, states[0] = -94.938987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141715743, states[0] = -94.877662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155900907, states[0] = -95.029243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170159082, states[0] = -86.511081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184443816, states[0] = -95.039005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198955218, states[0] = -95.040969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212981585, states[0] = -95.045000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227094830, states[0] = -13.933240, states[40]= 0.001622
Saving checkpoint... 
Iteration: 242371549, states[0] = -95.018318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256432477, states[0] = -95.036206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270857190, states[0] = -95.012319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285441503, states[0] = -95.038051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299692014, states[0] = -94.829419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314129424, states[0] = -47.087765, states[40]= 0.000045
Saving checkpoint... 
Iteration: 328413102, states[0] = -95.031470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342373234, states[0] = -95.018822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357009505, states[0] = 23.628927, states[40]= 0.059503
Saving checkpoint... 
Iteration: 371186928, states[0] = -94.817217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385037964, states[0] = 16.268812, states[40]= 0.005404
Saving checkpoint... 
Iteration: 399570754, states[0] = 2.885836, states[40]= 0.004574
Saving checkpoint... 
Iteration: 413878318, states[0] = -95.020659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427781472, states[0] = -94.962683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442345400, states[0] = -95.006658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456300710, states[0] = -94.978939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470487287, states[0] = -95.045412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484934830, states[0] = -95.036518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499081644, states[0] = -3.323967, states[40]= 0.003724
Saving checkpoint... 
Iteration: 513471916, states[0] = -95.043216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528504559, states[0] = 30.128421, states[40]= 0.151163
Saving checkpoint... 
Iteration: 542363739, states[0] = -95.014921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557067854, states[0] = 4.289971, states[40]= 0.004685
Saving checkpoint... 
Iteration: 571061396, states[0] = 7.188454, states[40]= 0.004845
Saving checkpoint... 
Iteration: 585144949, states[0] = -64.515796, states[40]= 0.000002
Saving checkpoint... 
Iteration: 599121963, states[0] = -39.488906, states[40]= 0.000141
Saving checkpoint... 
Iteration: 613078565, states[0] = -1.375832, states[40]= 0.004057
Saving checkpoint... 
Iteration: 628546488, states[0] = 13.153197, states[40]= 0.005079
Saving checkpoint... 
Iteration: 643205988, states[0] = -94.857605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657236391, states[0] = -94.909275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671873450, states[0] = -95.018695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685954933, states[0] = -95.040318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700954725, states[0] = -95.040272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715195720, states[0] = -94.837034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729575512, states[0] = 0.389926, states[40]= 0.004307
Saving checkpoint... 
Iteration: 743538524, states[0] = 16.072467, states[40]= 0.005372
Saving checkpoint... 
Iteration: 757670306, states[0] = -94.402785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772767208, states[0] = -94.948176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786962386, states[0] = -95.041534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801412876, states[0] = -95.031110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815429514, states[0] = -95.035146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829426119, states[0] = -95.034361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843521857, states[0] = 21.029386, states[40]= 0.008528
Saving checkpoint... 
Iteration: 857726397, states[0] = -94.893707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872123273, states[0] = -40.785820, states[40]= 0.000117
Saving checkpoint... 
Iteration: 886007854, states[0] = 24.551856, states[40]= 0.087082
Saving checkpoint... 
Iteration: 899991437, states[0] = -95.045678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913727909, states[0] = -94.896105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927928087, states[0] = -95.034753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942124671, states[0] = -42.186706, states[40]= 0.000095
Saving checkpoint... 
Iteration: 956335943, states[0] = -95.001437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970178315, states[0] = -94.770817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984306170, states[0] = -94.982684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998594590, states[0] = -13.706355, states[40]= 0.001657
Saving checkpoint... 
Iteration: 1012972536, states[0] = -95.042998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027324162, states[0] = -94.994625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041409660, states[0] = -95.030104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056096737, states[0] = -15.682491, states[40]= 0.001378
Saving checkpoint... 
Iteration: 1069855927, states[0] = -95.011222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083748249, states[0] = -94.925461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097840577, states[0] = -95.003806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111855357, states[0] = -95.010940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125879455, states[0] = -95.020624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139801823, states[0] = -94.979361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153744897, states[0] = -94.920963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168241353, states[0] = -94.916078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182297345, states[0] = -94.975861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196957715, states[0] = -95.040488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211245174, states[0] = -94.921301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225683812, states[0] = -94.806884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240049798, states[0] = 11.888520, states[40]= 0.005014
Saving checkpoint... 
Iteration: 1254182760, states[0] = -94.802596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268872786, states[0] = -95.018070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283070190, states[0] = 3.165232, states[40]= 0.004598
Saving checkpoint... 
Iteration: 1296973094, states[0] = -95.042905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310945574, states[0] = -95.038192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324796091, states[0] = -94.974771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338858703, states[0] = -95.012281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353319145, states[0] = -94.991295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367695944, states[0] = -94.837089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381787909, states[0] = -94.967886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395847777, states[0] = -95.007226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410286897, states[0] = -94.966982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424200750, states[0] = -94.846835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438656955, states[0] = -82.807473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452760608, states[0] = -94.940400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467370216, states[0] = -95.016954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481434860, states[0] = -95.035903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496710505, states[0] = -94.865625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510736144, states[0] = -95.216321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524993357, states[0] = -28.081848, states[40]= 0.000556
Saving checkpoint... 
Iteration: 1538944518, states[0] = -95.251841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552936076, states[0] = -85.620792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567545994, states[0] = 9.919350, states[40]= 0.005793
Saving checkpoint... 
Iteration: 1582167684, states[0] = -95.290949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596191868, states[0] = -95.187907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610223840, states[0] = -66.039841, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1624256477, states[0] = 4.049104, states[40]= 0.005301
Saving checkpoint... 
Iteration: 1638158629, states[0] = -95.103189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652735955, states[0] = 14.691473, states[40]= 0.006433
Saving checkpoint... 
Iteration: 1666287188, states[0] = -23.211316, states[40]= 0.000820
Saving checkpoint... 
Iteration: 1680308015, states[0] = 25.420966, states[40]= 0.080749
Saving checkpoint... 
Iteration: 1694762461, states[0] = 0.244773, states[40]= 0.004842
Saving checkpoint... 
Iteration: 1708602990, states[0] = -40.421456, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1723005962, states[0] = -43.809008, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1737053009, states[0] = 6.017277, states[40]= 0.005478
Saving checkpoint... 
Iteration: 1751222673, states[0] = -64.579049, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1764931380, states[0] = 16.724672, states[40]= 0.006950
Saving checkpoint... 
Iteration: 1779643875, states[0] = 10.857501, states[40]= 0.005897
Saving checkpoint... 
Iteration: 1793438771, states[0] = 13.361341, states[40]= 0.006206
Saving checkpoint... 
Iteration: 1807517905, states[0] = 21.403626, states[40]= 0.011614
Saving checkpoint... 
Iteration: 1821560979, states[0] = 6.589381, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1836391923, states[0] = -95.047662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850078803, states[0] = -2.052699, states[40]= 0.003964
Saving checkpoint... 
Iteration: 1863922911, states[0] = -95.043223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878197642, states[0] = -94.847104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892714338, states[0] = -94.876864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906674042, states[0] = -94.685591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920734405, states[0] = -94.907450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934706266, states[0] = -94.858582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949304261, states[0] = -94.981465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963294768, states[0] = -94.973805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977401691, states[0] = -95.027595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991235546, states[0] = -94.907384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005061242, states[0] = 7.251380, states[40]= 0.004848
Saving checkpoint... 
Iteration: 2018951856, states[0] = -95.038986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033163757, states[0] = -92.031306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047552834, states[0] = 10.702380, states[40]= 0.004969
Saving checkpoint... 
Iteration: 2061761966, states[0] = -94.941549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076112850, states[0] = -30.752174, states[40]= 0.000439
Saving checkpoint... 
Iteration: 2090052145, states[0] = 10.974339, states[40]= 0.004979
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.921799
 - CaMKt in component CaMK (millimolar): 0.006970
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.563201
 - nass in component intracellular_ions (millimolar): 6.563261
 - ki in component intracellular_ions (millimolar): 145.414602
 - kss in component intracellular_ions (millimolar): 145.414583
 - cansr in component intracellular_ions (millimolar): 1.311645
 - cajsr in component intracellular_ions (millimolar): 1.273597
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880346
 - hs in component INa (dimensionless): 0.880342
 - j in component INa (dimensionless): 0.880313
 - hsp in component INa (dimensionless): 0.726482
 - jp in component INa (dimensionless): 0.880294
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710217
 - hLp in component INaL (dimensionless): 0.451929
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620300
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694961
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934371
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334337
 - xs1 in component IKs (dimensionless): 0.243202
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:58:05 (37505): called boinc_finish(0)

</stderr_txt>
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