𝕏

Task 55974388

Name HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0
Workunit 26582122
Created 3 Jul 2024, 19:41:22 UTC
Sent 3 Jul 2024, 20:45:57 UTC
Report deadline 6 Jul 2024, 20:45:57 UTC
Received 4 Jul 2024, 6:10:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238179
Run time 56 min 18 sec
CPU time 53 min 12 sec
Validate state Valid
Credit 39.94
Device peak FLOPS 5.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.61 MB
Peak swap size 6.19 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.001069
     * GNaL_b in INaL: 0.005697
     * Gto_b in Ito: 0.086545
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031301
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164248
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.239830
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037179
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14337078, states[0] = 26.907871, states[40]= 0.096812
Saving checkpoint... 
Iteration: 29018381, states[0] = 17.912291, states[40]= 0.010706
Saving checkpoint... 
Iteration: 43101412, states[0] = -81.925940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57757599, states[0] = -67.097923, states[40]= 0.000003
Saving checkpoint... 
Iteration: 72092913, states[0] = -73.083645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85947084, states[0] = -87.663464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100215454, states[0] = -13.181195, states[40]= 0.002432
Saving checkpoint... 
Iteration: 115008944, states[0] = 18.273604, states[40]= 0.011080
Saving checkpoint... 
Iteration: 129440721, states[0] = -87.621975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143782318, states[0] = -87.734030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158082481, states[0] = -70.013472, states[40]= 0.000002
Saving checkpoint... 
Iteration: 172372227, states[0] = -9.576000, states[40]= 0.003381


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.001069
     * GNaL_b in INaL: 0.005697
     * Gto_b in Ito: 0.086545
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031301
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164248
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.239830
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037179
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 172372227
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -9.576000 (After loading)
 - states[40]: 0.003381 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 185720813, states[0] = -32.650945, states[40]= 0.000392
Saving checkpoint... 
Iteration: 200404592, states[0] = -58.750248, states[40]= 0.000010
Saving checkpoint... 
Iteration: 214806595, states[0] = -87.846710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228887247, states[0] = -38.245788, states[40]= 0.000200
Saving checkpoint... 
Iteration: 243434610, states[0] = -87.704674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257942173, states[0] = -87.755698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272238827, states[0] = -71.933361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286550365, states[0] = -41.290809, states[40]= 0.000133
Saving checkpoint... 
Iteration: 300852412, states[0] = -1.443073, states[40]= 0.005661
Saving checkpoint... 
Iteration: 315554078, states[0] = -50.513673, states[40]= 0.000035
Saving checkpoint... 
Iteration: 329659072, states[0] = 15.815451, states[40]= 0.008944
Saving checkpoint... 
Iteration: 343970456, states[0] = 27.714174, states[40]= 0.118342
Saving checkpoint... 
Iteration: 359037197, states[0] = -33.179598, states[40]= 0.000370
Saving checkpoint... 
Iteration: 373260361, states[0] = -87.739019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387858263, states[0] = -20.116430, states[40]= 0.001245
Saving checkpoint... 
Iteration: 402173931, states[0] = 0.199217, states[40]= 0.006023
Saving checkpoint... 
Iteration: 416740811, states[0] = -87.375122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431134521, states[0] = 22.050031, states[40]= 0.038609
Saving checkpoint... 
Iteration: 445346370, states[0] = -11.511783, states[40]= 0.002848
Saving checkpoint... 
Iteration: 459656045, states[0] = 9.774498, states[40]= 0.007489
Saving checkpoint... 
Iteration: 474072184, states[0] = -87.599841, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.001069
     * GNaL_b in INaL: 0.005697
     * Gto_b in Ito: 0.086545
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031301
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164248
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.239830
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037179
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 474072184
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.599841 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 488593639, states[0] = -87.786184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502661448, states[0] = 2.398308, states[40]= 0.006436
Saving checkpoint... 
Iteration: 516602861, states[0] = -87.826254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531109872, states[0] = -87.850676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545421473, states[0] = -87.786869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559817446, states[0] = 6.389143, states[40]= 0.007030
Saving checkpoint... 
Iteration: 573826735, states[0] = -3.138989, states[40]= 0.005238
Saving checkpoint... 
Iteration: 586995390, states[0] = -6.970940, states[40]= 0.004147
Saving checkpoint... 
Iteration: 599829527, states[0] = -9.640235, states[40]= 0.003363
Saving checkpoint... 
Iteration: 613565362, states[0] = -87.713144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628038154, states[0] = -74.713200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642673783, states[0] = -30.822675, states[40]= 0.000476
Saving checkpoint... 
Iteration: 657446606, states[0] = 21.510328, states[40]= 0.029581
Saving checkpoint... 
Iteration: 671624510, states[0] = 16.008789, states[40]= 0.009040
Saving checkpoint... 
Iteration: 685793390, states[0] = 13.984534, states[40]= 0.008285
Saving checkpoint... 
Iteration: 699938108, states[0] = 23.536134, states[40]= 0.069500
Saving checkpoint... 
Iteration: 714323657, states[0] = -17.353607, states[40]= 0.001616
Saving checkpoint... 
Iteration: 728780658, states[0] = 18.377684, states[40]= 0.011248
Saving checkpoint... 
Iteration: 743163521, states[0] = -30.527436, states[40]= 0.000490
Saving checkpoint... 
Iteration: 757248196, states[0] = -87.834159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771848935, states[0] = -61.021937, states[40]= 0.000007
Saving checkpoint... 
Iteration: 786589146, states[0] = 41.605610, states[40]= 0.034899


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pieske_333-conf_177_0_r1102033254_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.001069
     * GNaL_b in INaL: 0.005697
     * Gto_b in Ito: 0.086545
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031301
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164248
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.239830
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037179
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 786589146
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 41.605610 (After loading)
 - states[40]: 0.034899 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 803077354, states[0] = -87.835293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817513950, states[0] = -65.655760, states[40]= 0.000003
Saving checkpoint... 
Iteration: 831837878, states[0] = -53.511383, states[40]= 0.000022
Saving checkpoint... 
Iteration: 845907803, states[0] = -87.839292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860244247, states[0] = -87.851910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874730849, states[0] = -87.816863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889009002, states[0] = -69.358951, states[40]= 0.000002
Saving checkpoint... 
Iteration: 903347346, states[0] = -80.317111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917866939, states[0] = -87.701835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932507255, states[0] = -73.916427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946476095, states[0] = -29.938628, states[40]= 0.000520
Saving checkpoint... 
Iteration: 960951563, states[0] = 0.027466, states[40]= 0.005987
Saving checkpoint... 
Iteration: 975522408, states[0] = -87.610986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989865120, states[0] = -87.736987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004000761, states[0] = -75.069858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018537648, states[0] = -87.774350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032806622, states[0] = -37.936247, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1047075999, states[0] = 20.883789, states[40]= 0.022105
Saving checkpoint... 
Iteration: 1061002146, states[0] = -84.756283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075728809, states[0] = 33.703099, states[40]= 0.113039
Saving checkpoint... 
Iteration: 1090589678, states[0] = 11.901896, states[40]= 0.007828
Saving checkpoint... 
Iteration: 1105017762, states[0] = -87.723042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123161845, states[0] = -84.123489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143237070, states[0] = 19.310757, states[40]= 0.013325
Saving checkpoint... 
Iteration: 1163048860, states[0] = -87.855781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180758166, states[0] = 4.184497, states[40]= 0.006720
Saving checkpoint... 
Iteration: 1194806086, states[0] = -60.182124, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1209098165, states[0] = -4.962814, states[40]= 0.004735
Saving checkpoint... 
Iteration: 1223597297, states[0] = -5.645123, states[40]= 0.004538
Saving checkpoint... 
Iteration: 1237646180, states[0] = -78.668959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251381446, states[0] = 24.887739, states[40]= 0.092980
Saving checkpoint... 
Iteration: 1266089507, states[0] = -1.741775, states[40]= 0.005590
Saving checkpoint... 
Iteration: 1280521984, states[0] = -87.811219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294827998, states[0] = -87.688933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308991189, states[0] = -87.659938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323185022, states[0] = -87.813244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337647907, states[0] = -87.284868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351728707, states[0] = 12.842960, states[40]= 0.008012
Saving checkpoint... 
Iteration: 1365804939, states[0] = -84.713934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380052686, states[0] = 16.519301, states[40]= 0.009332
Saving checkpoint... 
Iteration: 1394331411, states[0] = -87.766153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408541478, states[0] = 20.270731, states[40]= 0.017435
Saving checkpoint... 
Iteration: 1422950254, states[0] = -60.664770, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1437299238, states[0] = -85.689713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451538626, states[0] = 19.700194, states[40]= 0.014656
Saving checkpoint... 
Iteration: 1466222457, states[0] = 9.495737, states[40]= 0.007450
Saving checkpoint... 
Iteration: 1480638145, states[0] = -87.597148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497831797, states[0] = -87.804968, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.734775
 - CaMKt in component CaMK (millimolar): 0.041699
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 6.963325
 - nass in component intracellular_ions (millimolar): 6.963473
 - ki in component intracellular_ions (millimolar): 144.959448
 - kss in component intracellular_ions (millimolar): 144.959415
 - cansr in component intracellular_ions (millimolar): 1.609520
 - cajsr in component intracellular_ions (millimolar): 1.180894
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007450
 - hf in component INa (dimensionless): 0.693138
 - hs in component INa (dimensionless): 0.692903
 - j in component INa (dimensionless): 0.681972
 - hsp in component INa (dimensionless): 0.448125
 - jp in component INa (dimensionless): 0.654794
 - mL in component INaL (dimensionless): 0.000193
 - hL in component INaL (dimensionless): 0.291626
 - hLp in component INaL (dimensionless): 0.135394
 - a in component Ito (dimensionless): 0.001011
 - iF in component Ito (dimensionless): 0.999542
 - iS in component Ito (dimensionless): 0.174491
 - ap in component Ito (dimensionless): 0.000515
 - iFp in component Ito (dimensionless): 0.999542
 - iSp in component Ito (dimensionless): 0.210956
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.802641
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966399
 - jca in component ICaL (dimensionless): 0.947183
 - ffp in component ICaL (dimensionless): 0.999854
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009360
 - xrf in component IKr (dimensionless): 0.029293
 - xrs in component IKr (dimensionless): 0.788566
 - xs1 in component IKs (dimensionless): 0.461024
 - xs2 in component IKs (dimensionless): 0.001230
 - xk1 in component IK1 (dimensionless): 0.996802
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:02:02 (13416): called boinc_finish(0)

</stderr_txt>
]]>


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