𝕏

Task 55973266

Name HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pueyo_APDR-conf_904_0
Workunit 26581562
Created 3 Jul 2024, 19:40:45 UTC
Sent 3 Jul 2024, 20:36:21 UTC
Report deadline 7 Jul 2024, 6:12:21 UTC
Received 5 Jul 2024, 16:15:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240525
Run time 1 hours 53 min 25 sec
CPU time 1 hours 16 min 42 sec
Validate state Valid
Credit 64.54
Device peak FLOPS 7.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pueyo_APDR-conf_904.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pueyo_APDR-conf_904_0_r146587825_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703214042255581_ORdGradInc_k_26-Pueyo_APDR-conf_904_0_r146587825_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.623876
     * GNaL_b in INaL: 0.005935
     * Gto_b in Ito: 0.083652
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031776
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.161408
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.402979
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035809
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12435822, states[0] = -95.090065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22775098, states[0] = -94.981775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34741177, states[0] = -94.919591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48558752, states[0] = 7.740941, states[40]= 0.004860
Saving checkpoint... 
Iteration: 60117887, states[0] = -37.169896, states[40]= 0.000192
Saving checkpoint... 
Iteration: 71721436, states[0] = -94.858711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83565901, states[0] = 4.933619, states[40]= 0.004711
Saving checkpoint... 
Iteration: 96234654, states[0] = -94.872677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109813799, states[0] = -94.952446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122521620, states[0] = 21.013885, states[40]= 0.008618
Saving checkpoint... 
Iteration: 134468324, states[0] = -95.004547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147141072, states[0] = -60.577213, states[40]= 0.000005
Saving checkpoint... 
Iteration: 160784025, states[0] = -94.925541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172906871, states[0] = -94.990150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184573298, states[0] = 1.502288, states[40]= 0.004416
Saving checkpoint... 
Iteration: 195641438, states[0] = -60.913017, states[40]= 0.000004
Saving checkpoint... 
Iteration: 207805858, states[0] = -94.942657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221066832, states[0] = 4.711398, states[40]= 0.004688
Saving checkpoint... 
Iteration: 232871052, states[0] = -94.977757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245429013, states[0] = -94.995053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258627084, states[0] = -45.201979, states[40]= 0.000059
Saving checkpoint... 
Iteration: 272342661, states[0] = -94.964993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283805305, states[0] = -94.941988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297051692, states[0] = 11.117992, states[40]= 0.004955
Saving checkpoint... 
Iteration: 312220076, states[0] = -94.842300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325378115, states[0] = -94.980245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339759401, states[0] = -94.898905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353619396, states[0] = -37.462989, states[40]= 0.000185
Saving checkpoint... 
Iteration: 367480970, states[0] = -95.004169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379369299, states[0] = -94.976868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392389674, states[0] = -94.984173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405477857, states[0] = -95.003707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417591130, states[0] = -10.827849, states[40]= 0.002160
Saving checkpoint... 
Iteration: 431360608, states[0] = -94.973258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444618517, states[0] = -36.607005, states[40]= 0.000208
Saving checkpoint... 
Iteration: 457232881, states[0] = -94.863086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468662702, states[0] = -91.154750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481668956, states[0] = -94.139948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494084820, states[0] = -5.683454, states[40]= 0.003239
Saving checkpoint... 
Iteration: 506799363, states[0] = -94.937317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518771941, states[0] = -94.912608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529295245, states[0] = -94.934018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541183096, states[0] = -94.761957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555205420, states[0] = -94.815189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568817631, states[0] = -94.950325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579880310, states[0] = -94.980869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591234328, states[0] = -94.865206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603905253, states[0] = -94.988760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615856175, states[0] = -94.971202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626342144, states[0] = -94.964474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640970958, states[0] = -95.002546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652540663, states[0] = 15.282826, states[40]= 0.005234
Saving checkpoint... 
Iteration: 664633177, states[0] = -51.675600, states[40]= 0.000021
Saving checkpoint... 
Iteration: 676299990, states[0] = -94.937701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688050361, states[0] = 11.637951, states[40]= 0.004975
Saving checkpoint... 
Iteration: 702755221, states[0] = -94.893660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714531313, states[0] = 18.446997, states[40]= 0.005945
Saving checkpoint... 
Iteration: 725582156, states[0] = -3.784517, states[40]= 0.003620
Saving checkpoint... 
Iteration: 738153341, states[0] = -77.032603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750143616, states[0] = -63.461177, states[40]= 0.000003
Saving checkpoint... 
Iteration: 762278940, states[0] = -94.919432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775094302, states[0] = -13.687552, states[40]= 0.001652
Saving checkpoint... 
Iteration: 787310754, states[0] = -94.945555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800595811, states[0] = -15.085869, states[40]= 0.001448
Saving checkpoint... 
Iteration: 814101775, states[0] = -20.700525, states[40]= 0.000919
Saving checkpoint... 
Iteration: 824306948, states[0] = -94.942828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834467436, states[0] = -95.001882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845284710, states[0] = -94.924767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855322225, states[0] = -94.953072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864064487, states[0] = 5.786860, states[40]= 0.004752
Saving checkpoint... 
Iteration: 872938005, states[0] = -94.996530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883755819, states[0] = -94.894279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894415253, states[0] = -94.991266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905210773, states[0] = -94.825179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914562821, states[0] = 6.525896, states[40]= 0.004789
Saving checkpoint... 
Iteration: 924726906, states[0] = -94.853360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935578742, states[0] = -1.577777, states[40]= 0.004006
Saving checkpoint... 
Iteration: 945274559, states[0] = -94.915011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955067248, states[0] = 4.520922, states[40]= 0.004676
Saving checkpoint... 
Iteration: 964186560, states[0] = -94.773944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974742086, states[0] = -94.876265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984958285, states[0] = -95.000287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995672974, states[0] = -94.572924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006365878, states[0] = -94.975107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016710778, states[0] = -94.825119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027881609, states[0] = -94.981052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039117856, states[0] = -35.965932, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1049084412, states[0] = -5.381674, states[40]= 0.003302
Saving checkpoint... 
Iteration: 1059227394, states[0] = -94.854067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069335790, states[0] = -94.960843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079397909, states[0] = -94.986328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089192441, states[0] = -94.788300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099293786, states[0] = -94.932468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109578518, states[0] = -1.440961, states[40]= 0.004028
Saving checkpoint... 
Iteration: 1120452540, states[0] = -94.999193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130245362, states[0] = -94.880682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139643192, states[0] = -62.951176, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1150118800, states[0] = -36.881606, states[40]= 0.000200
Saving checkpoint... 
Iteration: 1159155580, states[0] = -80.810290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169754213, states[0] = -94.892129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180767302, states[0] = -94.907292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191438511, states[0] = -94.996438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201555834, states[0] = 9.466820, states[40]= 0.004900
Saving checkpoint... 
Iteration: 1211808054, states[0] = -94.943385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222353360, states[0] = -94.969551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231253222, states[0] = -94.890857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241839241, states[0] = -94.962586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251592856, states[0] = -12.367436, states[40]= 0.001873
Saving checkpoint... 
Iteration: 1261391495, states[0] = -94.984224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271196650, states[0] = -94.797149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281892054, states[0] = -94.984389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291670658, states[0] = -94.385687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302075989, states[0] = 0.043016, states[40]= 0.004241
Saving checkpoint... 
Iteration: 1311600744, states[0] = -19.726769, states[40]= 0.000983
Saving checkpoint... 
Iteration: 1321275031, states[0] = -94.915252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331411006, states[0] = -94.989886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342304404, states[0] = -94.940641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351708045, states[0] = -94.819749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360186295, states[0] = -94.772920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370739735, states[0] = -94.872687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379088761, states[0] = -8.796045, states[40]= 0.002575
Saving checkpoint... 
Iteration: 1389668661, states[0] = -94.082538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400694426, states[0] = -94.792398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410901130, states[0] = -94.987080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420577352, states[0] = -0.743422, states[40]= 0.004133
Saving checkpoint... 
Iteration: 1430208606, states[0] = -94.820769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439984023, states[0] = -95.003922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451476413, states[0] = -95.002855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462243969, states[0] = -94.878575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472757864, states[0] = -94.896379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482912562, states[0] = -94.990205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492604813, states[0] = -23.566306, states[40]= 0.000770
Saving checkpoint... 
Iteration: 1501831139, states[0] = 17.561091, states[40]= 0.007055
Saving checkpoint... 
Iteration: 1512009817, states[0] = 24.453712, states[40]= 0.054600
Saving checkpoint... 
Iteration: 1523051651, states[0] = -95.214559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535900921, states[0] = -95.153307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547915322, states[0] = -95.185842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560298988, states[0] = -95.278414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573027473, states[0] = -71.553423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1585449335, states[0] = -95.242595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598993870, states[0] = -95.282864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609949157, states[0] = -94.863949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623029328, states[0] = 17.576105, states[40]= 0.007234
Saving checkpoint... 
Iteration: 1637469554, states[0] = -5.264774, states[40]= 0.003756
Saving checkpoint... 
Iteration: 1648768620, states[0] = -95.265761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661483364, states[0] = -19.369144, states[40]= 0.001102
Saving checkpoint... 
Iteration: 1675444307, states[0] = -95.241484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688032598, states[0] = -95.227138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702207859, states[0] = 25.382282, states[40]= 0.082775
Saving checkpoint... 
Iteration: 1716110825, states[0] = -50.095571, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1730987969, states[0] = -95.281702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744727790, states[0] = -95.220747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757543434, states[0] = -93.946926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767734864, states[0] = -85.225868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780886285, states[0] = -22.579980, states[40]= 0.000851
Saving checkpoint... 
Iteration: 1793085499, states[0] = -95.279890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807215499, states[0] = -94.881563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820774150, states[0] = -94.951967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833132645, states[0] = -53.057901, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1846504240, states[0] = 30.890167, states[40]= 0.153965
Saving checkpoint... 
Iteration: 1861258673, states[0] = -94.908856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875487371, states[0] = -95.011640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889686789, states[0] = -94.779222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901898014, states[0] = -94.989267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915436998, states[0] = -94.997944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928355696, states[0] = -94.971710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940841080, states[0] = -94.964159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954689761, states[0] = -94.782340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967383836, states[0] = -94.981692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980568541, states[0] = 3.900162, states[40]= 0.004632
Saving checkpoint... 
Iteration: 1992647234, states[0] = -68.043098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2005839374, states[0] = -94.962291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017563445, states[0] = 6.248979, states[40]= 0.004776
Saving checkpoint... 
Iteration: 2028140088, states[0] = -59.336188, states[40]= 0.000006
Saving checkpoint... 
Iteration: 2038981403, states[0] = -95.003202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050101699, states[0] = -20.630487, states[40]= 0.000924
Saving checkpoint... 
Iteration: 2063673829, states[0] = -94.614727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077387257, states[0] = -94.982302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088045098, states[0] = 13.647261, states[40]= 0.005081
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.881336
 - CaMKt in component CaMK (millimolar): 0.006905
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.555208
 - nass in component intracellular_ions (millimolar): 6.555267
 - ki in component intracellular_ions (millimolar): 145.423897
 - kss in component intracellular_ions (millimolar): 145.423877
 - cansr in component intracellular_ions (millimolar): 1.305881
 - cajsr in component intracellular_ions (millimolar): 1.267913
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003626
 - hf in component INa (dimensionless): 0.879644
 - hs in component INa (dimensionless): 0.879640
 - j in component INa (dimensionless): 0.879611
 - hsp in component INa (dimensionless): 0.725159
 - jp in component INa (dimensionless): 0.879592
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709223
 - hLp in component INaL (dimensionless): 0.450920
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620481
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695105
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934677
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333010
 - xs1 in component IKs (dimensionless): 0.242652
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997343
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:14:40 (355555): called boinc_finish(0)

</stderr_txt>
]]>


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