𝕏

Task 55971983

Name HuVeMOp_20240703211647185001_ORdGradInc_k_26-Pueyo_APDR-conf_65_0
Workunit 26580971
Created 3 Jul 2024, 19:17:19 UTC
Sent 3 Jul 2024, 20:31:26 UTC
Report deadline 7 Jul 2024, 6:07:26 UTC
Received 4 Jul 2024, 5:08:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230595
Run time 2 hours 29 min 8 sec
CPU time 2 hours 27 min 47 sec
Validate state Valid
Credit 74.96
Device peak FLOPS 4.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211647185001_ORdGradInc_k_26-Pueyo_APDR-conf_65.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211647185001_ORdGradInc_k_26-Pueyo_APDR-conf_65_0_r979888902_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211647185001_ORdGradInc_k_26-Pueyo_APDR-conf_65_0_r979888902_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.252067
     * GNaL_b in INaL: 0.005998
     * Gto_b in Ito: 0.081301
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031693
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.160085
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.787534
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029655
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15147448, states[0] = -75.233229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30382720, states[0] = -95.013407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44747873, states[0] = -94.897635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59280720, states[0] = -94.924896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74257612, states[0] = -94.893089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88968850, states[0] = -94.997408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104463886, states[0] = -94.993858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119504130, states[0] = 31.678811, states[40]= 0.154713
Saving checkpoint... 
Iteration: 133997990, states[0] = -94.995995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148848567, states[0] = -94.955610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164072604, states[0] = 1.768534, states[40]= 0.004482
Saving checkpoint... 
Iteration: 178256300, states[0] = -94.880244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193748230, states[0] = -94.869575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209317543, states[0] = -94.936579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223796294, states[0] = -94.920646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238265521, states[0] = -94.890692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253678202, states[0] = -94.700881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269038662, states[0] = 16.030196, states[40]= 0.005370
Saving checkpoint... 
Iteration: 284052302, states[0] = 10.862090, states[40]= 0.004990
Saving checkpoint... 
Iteration: 298303823, states[0] = -94.926474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312668654, states[0] = -93.984525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326876487, states[0] = -94.966356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341775993, states[0] = -94.901775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356297063, states[0] = -94.921054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370786632, states[0] = -94.912008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385213718, states[0] = -94.813745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400390466, states[0] = -94.971275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415128472, states[0] = -46.572510, states[40]= 0.000049
Saving checkpoint... 
Iteration: 429748470, states[0] = -94.869397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444445874, states[0] = -94.985643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459343513, states[0] = -94.951562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475024170, states[0] = 20.555887, states[40]= 0.007445
Saving checkpoint... 
Iteration: 489962068, states[0] = -94.988596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504803439, states[0] = -94.926030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519948662, states[0] = -94.986141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534581517, states[0] = -3.478602, states[40]= 0.003709
Saving checkpoint... 
Iteration: 549113164, states[0] = -31.494683, states[40]= 0.000405
Saving checkpoint... 
Iteration: 563823394, states[0] = -94.939943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579265931, states[0] = -94.890842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594756826, states[0] = -94.880078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611071828, states[0] = 2.193926, states[40]= 0.004525
Saving checkpoint... 
Iteration: 626425518, states[0] = -94.981078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641297683, states[0] = -94.921377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656215712, states[0] = -94.817265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671417024, states[0] = -94.978928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686175585, states[0] = -94.645475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701139746, states[0] = -58.782760, states[40]= 0.000006
Saving checkpoint... 
Iteration: 716470144, states[0] = -94.989778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730940100, states[0] = -94.984283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746155012, states[0] = -79.399794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760902926, states[0] = -94.974959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776735165, states[0] = -94.850009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792573075, states[0] = 1.541774, states[40]= 0.004457
Saving checkpoint... 
Iteration: 808236545, states[0] = -94.852096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822913268, states[0] = -94.977839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838274687, states[0] = -94.900116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853690329, states[0] = -94.765293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869324647, states[0] = -94.940536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884415441, states[0] = -94.978379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899377411, states[0] = -94.966333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914214328, states[0] = -94.814542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928748808, states[0] = -94.869531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943480419, states[0] = -94.991182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958597509, states[0] = -16.801257, states[40]= 0.001251
Saving checkpoint... 
Iteration: 974474701, states[0] = -94.990319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989261545, states[0] = -94.885525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004695854, states[0] = -94.777637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019000908, states[0] = 46.723117, states[40]= 0.021261
Saving checkpoint... 
Iteration: 1034316145, states[0] = -94.934891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049401210, states[0] = -94.974263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064499814, states[0] = -94.993644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079443771, states[0] = -94.984817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094219604, states[0] = -94.824021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108710649, states[0] = -94.807476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123784578, states[0] = -94.909631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138135977, states[0] = -54.603291, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1152613180, states[0] = -31.509464, states[40]= 0.000405
Saving checkpoint... 
Iteration: 1167445937, states[0] = -94.985195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182137247, states[0] = -55.997703, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1196504182, states[0] = 31.493904, states[40]= 0.154261
Saving checkpoint... 
Iteration: 1211463447, states[0] = -94.988371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226559978, states[0] = 7.707448, states[40]= 0.004882
Saving checkpoint... 
Iteration: 1240885477, states[0] = -94.969039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255175292, states[0] = -94.636037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270306851, states[0] = -94.928127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285163077, states[0] = -91.182403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300344476, states[0] = -94.951525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314881504, states[0] = -94.967580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329367574, states[0] = -94.962180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344355586, states[0] = -94.956925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358462707, states[0] = -94.988153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373354211, states[0] = -94.956266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388597838, states[0] = -17.108786, states[40]= 0.001219
Saving checkpoint... 
Iteration: 1404092278, states[0] = -11.991009, states[40]= 0.001955
Saving checkpoint... 
Iteration: 1418904209, states[0] = -94.974918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433356478, states[0] = -94.957280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448200920, states[0] = -94.787962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463286930, states[0] = -94.911580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478283516, states[0] = -94.908410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493616020, states[0] = -34.204197, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1507713305, states[0] = -95.134773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522348011, states[0] = -94.399198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536854833, states[0] = -95.217851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552262461, states[0] = 0.474101, states[40]= 0.004879
Saving checkpoint... 
Iteration: 1566581522, states[0] = -95.256686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580861567, states[0] = -95.061575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595897866, states[0] = -95.154237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610877539, states[0] = -95.110959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625254288, states[0] = -95.008530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640194699, states[0] = -31.640720, states[40]= 0.000391
Saving checkpoint... 
Iteration: 1654922511, states[0] = -64.558361, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1669030524, states[0] = -76.828766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683422554, states[0] = -64.640307, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1697720095, states[0] = 21.052623, states[40]= 0.011041
Saving checkpoint... 
Iteration: 1711952273, states[0] = -94.968593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726959371, states[0] = -95.057551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741720439, states[0] = -95.197191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756887583, states[0] = -23.986163, states[40]= 0.000775
Saving checkpoint... 
Iteration: 1771656534, states[0] = -95.037840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786652312, states[0] = -94.969769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801043099, states[0] = 13.349724, states[40]= 0.005178
Saving checkpoint... 
Iteration: 1815327900, states[0] = -94.985799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830120394, states[0] = -40.275533, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1845268773, states[0] = -94.912370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859915543, states[0] = -94.990067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874205894, states[0] = -94.805927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889347929, states[0] = -94.958038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904011707, states[0] = 23.082630, states[40]= 0.035557
Saving checkpoint... 
Iteration: 1918513047, states[0] = 22.810302, states[40]= 0.026755
Saving checkpoint... 
Iteration: 1933260787, states[0] = -94.885419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948213330, states[0] = -94.812903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962367406, states[0] = -94.962262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977196265, states[0] = -94.778237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991811563, states[0] = -94.931299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006763482, states[0] = -94.887248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021638137, states[0] = -56.989853, states[40]= 0.000009
Saving checkpoint... 
Iteration: 2036411737, states[0] = -94.976667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050773739, states[0] = -94.898350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065055571, states[0] = 9.545652, states[40]= 0.004946
Saving checkpoint... 
Iteration: 2079464566, states[0] = -94.987970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094008208, states[0] = 24.442881, states[40]= 0.079703
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.868839
 - CaMKt in component CaMK (millimolar): 0.006998
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.597013
 - nass in component intracellular_ions (millimolar): 6.597073
 - ki in component intracellular_ions (millimolar): 145.380048
 - kss in component intracellular_ions (millimolar): 145.380029
 - cansr in component intracellular_ions (millimolar): 1.314521
 - cajsr in component intracellular_ions (millimolar): 1.276517
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003631
 - hf in component INa (dimensionless): 0.879427
 - hs in component INa (dimensionless): 0.879422
 - j in component INa (dimensionless): 0.879392
 - hsp in component INa (dimensionless): 0.724749
 - jp in component INa (dimensionless): 0.879372
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708817
 - hLp in component INaL (dimensionless): 0.450328
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620258
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694817
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934515
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333961
 - xs1 in component IKs (dimensionless): 0.242425
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997346
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:07:11 (160815): called boinc_finish(0)

</stderr_txt>
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